Mustela nigripes (black-footed ferret): 132019988
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Entry
132019988 CDS
T09425
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04010
MAPK signaling pathway
mnp04020
Calcium signaling pathway
mnp04022
cGMP-PKG signaling pathway
mnp04024
cAMP signaling pathway
mnp04260
Cardiac muscle contraction
mnp04261
Adrenergic signaling in cardiomyocytes
mnp04270
Vascular smooth muscle contraction
mnp04713
Circadian entrainment
mnp04720
Long-term potentiation
mnp04723
Retrograde endocannabinoid signaling
mnp04724
Glutamatergic synapse
mnp04725
Cholinergic synapse
mnp04726
Serotonergic synapse
mnp04727
GABAergic synapse
mnp04728
Dopaminergic synapse
mnp04742
Taste transduction
mnp04911
Insulin secretion
mnp04912
GnRH signaling pathway
mnp04921
Oxytocin signaling pathway
mnp04924
Renin secretion
mnp04925
Aldosterone synthesis and secretion
mnp04927
Cortisol synthesis and secretion
mnp04929
GnRH secretion
mnp04930
Type II diabetes mellitus
mnp04934
Cushing syndrome
mnp04935
Growth hormone synthesis, secretion and action
mnp05010
Alzheimer disease
mnp05020
Prion disease
mnp05022
Pathways of neurodegeneration - multiple diseases
mnp05031
Amphetamine addiction
mnp05207
Chemical carcinogenesis - receptor activation
mnp05410
Hypertrophic cardiomyopathy
mnp05412
Arrhythmogenic right ventricular cardiomyopathy
mnp05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
132019988 (CACNA1C)
04020 Calcium signaling pathway
132019988 (CACNA1C)
04024 cAMP signaling pathway
132019988 (CACNA1C)
04022 cGMP-PKG signaling pathway
132019988 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
132019988 (CACNA1C)
04929 GnRH secretion
132019988 (CACNA1C)
04912 GnRH signaling pathway
132019988 (CACNA1C)
04921 Oxytocin signaling pathway
132019988 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
132019988 (CACNA1C)
04924 Renin secretion
132019988 (CACNA1C)
04925 Aldosterone synthesis and secretion
132019988 (CACNA1C)
04927 Cortisol synthesis and secretion
132019988 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
132019988 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
132019988 (CACNA1C)
04270 Vascular smooth muscle contraction
132019988 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
132019988 (CACNA1C)
04727 GABAergic synapse
132019988 (CACNA1C)
04725 Cholinergic synapse
132019988 (CACNA1C)
04728 Dopaminergic synapse
132019988 (CACNA1C)
04726 Serotonergic synapse
132019988 (CACNA1C)
04720 Long-term potentiation
132019988 (CACNA1C)
04723 Retrograde endocannabinoid signaling
132019988 (CACNA1C)
09157 Sensory system
04742 Taste transduction
132019988 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
132019988 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
132019988 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
132019988 (CACNA1C)
05020 Prion disease
132019988 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
132019988 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
132019988 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
132019988 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
132019988 (CACNA1C)
05414 Dilated cardiomyopathy
132019988 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
132019988 (CACNA1C)
04934 Cushing syndrome
132019988 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mnp04040
]
132019988 (CACNA1C)
Ion channels [BR:
mnp04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
132019988 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Etmic-2
Motif
Other DBs
NCBI-GeneID:
132019988
NCBI-ProteinID:
XP_059259884
LinkDB
All DBs
Position
6:106365862..107007496
Genome browser
AA seq
2191 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKYPLPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK
VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT
CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF
QCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKA
RGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTE
NVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLN
TLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVC
GGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLL
LFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM
AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKK
LARTASPEKKQEVVEKPAVEETKEEKIELKSITADGESPPTTKINMDDLQPNENEDKSPY
PNPENTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIV
NDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNAD
YVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKIL
RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYT
CSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGW
PELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEY
KNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLA
MQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIID
VILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFR
LFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALND
TTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPGNSTEGETPCGS
SFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAK
GRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTA
LRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFR
KFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSA
ASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAANSQGDTESPSHEKLV
DSTFTPSSYSSTGSNANINNANNTALGRFPRPAGYPSAVSTVEGHRPPLSPAVRVQEAAW
KLSSKRCHSRESQIAMVCQEEVSQDETYEVKLSEDTEYCSEPSLISTELLSYQDDENRQL
TPPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHHQA
LAVAGLSPLLQRSHSPSTFPRPCATPPATPGSQGWPPQPIPTLRLEGAESSEKLNSSFPT
IHCSSWSGEPAPCGGGSSALRRARPVSLTVPSQAGARGRPFYGSASSLVGAVLISEGLGQ
FAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRA
GGQEGESCTGARACRKSEEERQDSRAHAGSL
NT seq
6576 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgagaacacgaggatgtacattccagaggaaaatcatcaaggttccaactat
gggagcccgcgcccagctcacgccaacatgaatgccaatgctgctgcggggctcgcccct
gagcacatccctacgccgggggccgccttgtcctggcaggcagccattgatgcggcccgg
caggccaagctgatgggcagcgccggcaacgcgaccatctccacggtcagctccacgcag
cggaagcggcagcagtatgggaagcccaagaagcagggcagcacgacggccacgcgccca
ccccgcgccctgctctgcctgactctgaagaaccccatcaggagggcgtgcatcagcatc
gtcgaatggaaatatcctttaccatttgaaataattattttactgactatttttgccaat
tgtgtggccttagcgatctatattccctttccagaagacgactccaacgccaccaattct
aacctggaacgagtggaatatctctttctcataatttttactgtggaagcatttttaaaa
gtaatagcctatggacttctctttcaccccaacgcttacctccgcaatggttggaattta
ctagattttataattgtggttgtagggctttttagtgcaattttagaacaagcaaccaaa
gccgatggggcaaacgctctgggagggaaaggagctggatttgacgtgaaggcactgagg
gcattccgcgtgctgcgcccattgcgcctggtgtctggagtcccaagcctccaggtggtt
ctgaattccattatcaaggctatggtgcccctgctgcatattgccctgttagtgctgttt
gtcatcatcatctacgccatcatcggcctggagctcttcatggggaaaatgcataagacc
tgctacaaccaggaaggcatagcagatgttccagcagaagatgatccttccccttgtgct
ctggagacaggccatgggcggcagtgtcagaacggcactgtgtgcaagcccgggtgggac
gggcccaagcacggcatcaccaacttcgacaattttgccttcgccatgttgacagtgttc
cagtgcatcaccatggagggctggacagatgtgctgtactgggtcaatgatgccgtagga
agggactggccctggatctattttgttacactaatcatcatagggtcattttttgtactt
aacttggttctcggtgttcttagcggagagttttccaaagagagagagaaggccaaagct
cgaggagatttccagaagcttcgagagaagcagcagctagaagaggacctgaagggctac
ctggactggatcacccaggcagaggatattgaccccgagaatgaggatgaaggcatggat
gaagaaaagccccgaaacatgagcatgcccacaagcgagaccgagtctgtcaacactgaa
aacgtggctggaggtgacatcgagggagagaactgcggggccaggctggcccaccggatt
tccaaatcaaagttcagccgctactggcgccggtggaatcggttctgtagaagaaagtgt
cgtgctgcagtcaagtctaatgtcttctactggcttgtgatcttccttgtgttcctcaac
acactcaccattgcctcagaacactacaaccagccgcactggctcacggaggtccaagac
acggccaacaaggcactgctggcccttttcactgcagagatgctgctgaagatgtacagc
ctgggcctgcaggcctactttgtgtccctcttcaaccgtttcgactgcttcattgtgtgt
gggggcatcctggagaccatcctggtagagaccaagatcatgtctcccttgggcatctct
gtgctgagatgtgtccggctactgcggatatttaaaatcacaaggtactggaactcctta
agcaacctggtggcatccttgctgaattctgtacgctccattgcctctctgctgctgctc
ctcttcctcttcatcatcatcttctccctcctggggatgcagctctttggaggaaagttc
aactttgatgaaatgcagacccggaggagcacatttgataactttccccagtcccttctc
accgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatg
gcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttc
atctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaacctggcg
gatgctgagagcctcacgtctgcccaaaaggaggaggaagaagagaaggagagaaagaag
ctggccaggactgccagcccagagaagaaacaagaggtggtggagaagccagcagtggaa
gagaccaaggaggagaaaattgaactgaaatctattactgctgatggagagtccccaccc
accaccaagatcaacatggatgacctccagcccaatgaaaatgaggataagagtccctac
cccaacccagaaaatacaggagaagaggatgaggaggagcctgagatgcctgtgggcccc
cgcccccgcccactctcggagctgcacctgaaggaaaaggcagtgcccatgccagaagcc
agtgcatttttcatcttcagccccaacaacagatttcgcctccagtgtcaccgcattgtc
aatgacacgatcttcaccaacctgatcctcttcttcattctgctcagcagcatttccctg
gcggctgaggaccccgtccagcacacctccttcaggaaccatattctgttttattttgac
attgttttcactaccattttcaccattgaaattgctctgaagatcctaggcaatgcagac
tatgtcttcactagtatctttacattagaaattatccttaagatgactgcttatggggct
ttcctacacaagggctctttttgccgaaactacttcaacatcttggacctgctggtggtc
agcgtgtccctcatttcctttgggatccagtccagtgcaatcaatgtggtgaagatcttg
cgagtcctgagagtcctcaggcccctgagggccatcaacagggccaaggggctaaagcac
gtggttcagtgcgtgttcgttgctatccggaccatcgggaacattgtgattgtcaccacg
ctgcttcagttcatgttcgcctgcatcggtgtgcagcttttcaagggaaagctctacacc
tgctcagatagttccaaacagactgaggcagaatgcaagggtaactacatcacatacaaa
gatggggaggtcgatcaccctatcatccaaccccgcagctgggagaacagcaagtttgac
tttgacaacgttctggcagccatgatggccctctttactgtctctacctttgagggatgg
ccagagctgctgtaccgctccatcgactcccacacagaagacaagggccccatctacaac
taccgtgtggagatctccatctttttcatcatctacatcatcatcattgccttcttcatg
atgaacatcttcgtgggtttcgtcatcgtcaccttccaggagcagggggagcaggaatac
aagaactgtgagctggacaagaaccagcgacaatgcgtggaatatgccctcaaggcccgg
cccctgcggaggtacatccccaagaaccagcaccagtacaaagtgtggtacgtggtcaac
tccacctactttgaatacctgatgttcgtcctcatccttctcaacaccatctgcttggcc
atgcagcactatggccagagctgcctcttcaaaattgccatgaacatcctcaacatgctc
ttcactggcctcttcaccgtggagatgattctgaagctcattgccttcaaacccaagggt
tactttagtgatccctggaatgtttttgacttcctcatcgtaattggcagcataattgac
gtcattctcagtgaaactaatcactatttctgtgatgcatggaatacatttgacgccttg
attgttgtgggtagcattgttgatatagcaatcaccgaggtaaacccagctgaacatacc
caatgctctccctttatgaacgcagaggagaactcccgcatctccatcaccttcttccgc
ctcttccgggtcatgcgcctggtcaaactgctgagccgaggggagggcatccggaccttg
ctgtggaccttcatcaagtccttccaggccctgccctatgtggctcttctgatagtgatg
ctgttcttcatctacgcagtgatcgggatgcaggtgtttgggaaaattgccctgaatgac
accacagagatcaaccggaacaacaacttccagacctttccccaagctgtgctgcttctc
ttcaggtgtgccacaggggaggcatggcaggatatcatgctggcctgcatgccaggaaag
aagtgtgcccccgagtcagagcccggcaacagcacagaaggtgaaactccctgtggcagc
agcttcgcggtcttctacttcatcagcttctacatgctctgtgccttcctgatcatcaac
ctctttgtagctgtcatcatggacaactttgactacctgacaagggactggtcaattctt
ggtccccatcatctggatgaatttaaaagaatctgggcagagtatgatcctgaagccaag
ggtcggatcaaacacctggatgtggtgaccctgctcaggcggattcagcccccactgggt
tttgggaagctatgccctcaccgcgtggcttgcaaacgcctggtctccatgaacatgcct
ctgaacagtgatgggacagtcatgttcaatgctaccctgtttgccctggtccggacagcc
ctgcggattaaaacagaagggaacctagaacaagccaatgaggaactgcgggccataatc
aagaagatctggaagcggaccagcatgaagctgctggaccaagtggtgcccccagcgggt
gatgacgaggtcacagttggcaagttttatgctactttcctgatccaagagtacttccgg
aaattcaagaagcgcaaagagcagggcctggtgggcaaaccctcccagaggaacgcccta
tccctgcaggctggcttgcgcacgctgcatgacatcgggcctgagatccgacgggccatt
tctggagatctgacggctgaggaggagttggacaaggccatgaaggaggctgtgtctgct
gcctctgaagatgacatcttccggagggccggtggcctgttcggcaaccacgtcagctac
taccaaagtgacggccggagcgccttcccccagaccttcaccacccagcgcccactgcac
atcaacaaggcggctaacagccaaggcgacaccgagtcgccatcccacgagaaactggtg
gactccactttcacccccagcagctactcatccactggctccaacgccaacatcaacaat
gccaacaacactgccctgggccgcttcccccgccccgctggctaccccagcgcagtcagc
accgtggagggccacaggccccccttgtctcctgccgtccgggtacaggaggccgcatgg
aagctcagctccaagaggtgccactcccgggagagccagatcgccatggtgtgtcaggag
gaggtctctcaggacgagacctatgaggtgaagctgagcgaggacacagagtactgcagc
gagcccagcctgatctctacagagctgctctcctatcaggatgatgaaaaccggcaatta
acaccgcctgaggaggacaagagagacatccggcaatctccaaagaggggtttcctccgc
tctgcctcactaggtcgaagggcctccttccacctggaatgtctgaagcgacagaagaat
caaggcggagacatctctcagaagacagtcctgcccttgcatctggttcatcatcaggca
ttggcagtggcgggcctgagccccctcctccagagaagccattcaccgagcacgttcccc
aggccgtgcgccacgcccccagccacacccggcagtcaaggctggcccccgcagcccatc
cccaccctgcggctggagggggccgagtccagcgagaaactcaacagcagcttcccgacc
atccactgcagctcctggtccggggagcccgcgccctgcggtgggggcagcagcgccctg
cggagagcccggccggtgtccctcactgtgcccagccaggctggggcccggggccggccg
ttctacggcagtgccagcagcctggtgggagcggtcttgatttcagaaggactggggcag
tttgctcaagatcccaagtttatcgaggtcacaacccaggagctggctgacgcatgtgac
atgaccatagaggagatggagaacgccgctgacaacatcctcagtgggggcgcccagcag
agccccaacggcaccctactaccttttgttaactgcagggacccagggcaggacagagcg
gggggccaagagggcgagagctgcactggggctcgggcgtgtcggaagagcgaggaggag
cgccaggacagcagagcccacgccggcagcctgtag
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integrated database retrieval system
