Mycolicibacterium poriferae: MPOR_24690
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Entry
MPOR_24690 CDS
T07158
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mpof
Mycolicibacterium poriferae
Pathway
mpof00290
Valine, leucine and isoleucine biosynthesis
mpof00660
C5-Branched dibasic acid metabolism
mpof01100
Metabolic pathways
mpof01110
Biosynthesis of secondary metabolites
mpof01210
2-Oxocarboxylic acid metabolism
mpof01230
Biosynthesis of amino acids
Module
mpof_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mpof00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MPOR_24690 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MPOR_24690 (leuC)
Enzymes [BR:
mpof01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MPOR_24690 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MPOR_24690 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BBX51443
UniProt:
A0A6N4VBE3
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All DBs
Position
2581280..2582725
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AA seq
481 aa
AA seq
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MALAHQPRTMAEKVWNDHVVVSGTGEGGARQPDLIYIDLHLVHEVTSPQAFDGLRLAGRP
VRRPDLTIATEDHNVPTVDIDKPIVDPVSRTQVETLRRNCDEFGIRLHPMGDAEQGIVHI
IGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNV
DGRLPAGVSAKDIILAVIAKIGTGGGQGHVIEYRGTAIESLSMEGRMTICNMSIEAGARA
GMVAPDETTFEFLRGRPHAPQGAAWDTAVEAWSQLRTDDGAAFDTEVYLDASTLSPFVTW
GTNPGQGVPLAGSVPDPELMLDEGERQSAEKALAYMDLRPGMAMRDITVDTVFVGSCTNG
RIEDLRVVADVLRGRRVADGVRMLVVPGSMRVRAQAEAEGLGEVFTAAGAEWRQAGCSMC
LGMNPDQLSPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLPAAPA
R
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atggccctcgcgcaccagccccgcaccatggccgaaaaggtgtggaacgaccacgtcgtc
gtttccggaaccggagagggcggggcacgtcaacccgacctcatctacatcgacctgcat
ctggttcacgaagtgaccagtccgcaggccttcgacgggctgcggctcgccggtcgtccc
gtacgcaggccggacctgacgatcgcgaccgaagaccacaatgtgccgaccgtcgacatc
gacaagccgatcgtggatccggtttctcgcacgcaggtcgagacgctgcgccgcaactgc
gacgagttcggcatccggctgcacccgatgggtgacgccgagcagggcatcgtgcacatc
atcgggccgcaactcgggttgacccagcccgggatgacggtggtctgtggtgacagccac
acctccacccatggcgccttcggtgcgctggccatgggcatcggcacatccgaggtcgag
cacgtgctcgcgacccagacgctgccgctgcggccgttcaagaccatggcggtcaacgtc
gacggccggcttccagcgggcgtcagcgccaaagacatcatcctggcggtcatcgccaag
atcggcaccggcggtgggcagggccacgtgatcgaataccgcggcaccgccatcgaatcg
ctgtcgatggaaggccggatgacgatctgcaacatgagcatcgaagccggcgcccgagcg
ggcatggtcgcccccgacgagaccaccttcgagttcctgcggggtcgaccccacgcgcct
cagggcgccgcctgggacaccgcggtcgaagcgtggagtcagctgcgtaccgacgacggc
gccgcattcgacaccgaggtctacctcgacgcgtcgacgctgagtcccttcgtgacgtgg
ggaacgaatcccggacagggcgtaccgctggcgggttcggtgccggacccggaactgatg
ctcgacgagggagagcggcagtctgccgagaaggcgttggcctacatggaccttcgcccg
ggaatggcgatgcgcgacatcaccgtcgacacggtgttcgtcgggtcctgcaccaacgga
cgcatcgaggatctgcgcgtcgtcgccgacgtcctgcggggccgccgtgtcgccgacggg
gttcggatgttggtggtgcccggatcgatgcgcgtgcgcgcccaagccgaagccgaaggg
ctgggcgaggtgttcaccgcggccggggccgagtggcggcaggcggggtgctcgatgtgc
ttgggaatgaaccccgatcagctctctccgggccagcgctgcgcgtccacgtcgaaccgg
aacttcgaaggccggcagggcaagggcggccgcacccacctggtttcgcctgcggtcgcg
gccgcgaccgcggtccgtggcaccttgtcctcgcctgccgatctgcccgcggccccggcc
cgctga
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