Mustela putorius furo (domestic ferret): 101694556
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Entry
101694556 CDS
T07239
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
mpuf
Mustela putorius furo (domestic ferret)
Pathway
mpuf00230
Purine metabolism
mpuf00670
One carbon pool by folate
mpuf01100
Metabolic pathways
mpuf01523
Antifolate resistance
Module
mpuf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mpuf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101694556 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101694556 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101694556 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mpuf04147
]
101694556 (ATIC)
Enzymes [BR:
mpuf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
101694556 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
101694556 (ATIC)
Exosome [BR:
mpuf04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
101694556 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
101694556
NCBI-ProteinID:
XP_004767060
Ensembl:
ENSMPUG00000007676
UniProt:
A0A8U0S280
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MAPSQLALFSVSDKTGLVEFARNLTSVGLHLIASGGTAKALREAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFSLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVSTEMQSSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEDEALKILSKKKNG
NYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKDLSESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVDKLSEVSLSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccagccagctcgccttatttagtgtctctgacaaaacgggcctcgtggaattt
gccagaaacctaacttctgttggtttgcatctgatcgcctctggagggactgcgaaagct
ctgagggaggcgggcctggcagtcagagatgtctctgagctgacgggatttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgccgtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgatttcagtcttataagagttgtcgtc
tgcaatctgtatccctttgtgaagacagtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggcggagtaaccctactgagagcagcagccaaaaaccatgct
cgggtgacagtagtatgtgaacccgaggactatgcagctgtgtccacagagatgcagagc
tctgacagcaaagacacttccttggagaccagacgtcagttagccttgaaggcctttact
catacggcacaatatgatgaagcaatttcagattacttcaggagacagtatagtaaagga
atatctcagatgcctttgaggtatggaatgaaccctcatcagactcctgcccagttatac
acgctgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcaaagaagctttaggcattcca
gctgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactcagt
gaagacgaggccaaagtctgcatggtctatgatctgtataaaacgcttacacccatatca
actgcatatgcaagagcaagaggggctgataggatgtcttcatttggtgactttgttgca
ttatctgatgtttgtgatgttcctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggatatgaagatgaagctttgaaaatactttctaaaaaaaaaaatgga
aactactgtgttcttcagatggatcagtcctacaatccagatgaaaacgaagttcgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaggtcattattt
agcaacgttgtgaccaagaataaagatttgtcagagtctgcgctcagagacctcattgta
gccaccattgctgtgaagtacacgcagtctaactccgtgtgctatgccaagaatggtcag
gttattggcattggagcaggacagcagtctcgaatacactgcacacgccttgcaggggat
aaagcaaattattggtggcttagacatcatccacaagtcctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccattggc
gaggatgaggatttgataaagtggaaggcattgtttgaagaagtgcctgaattattaact
gaagcagagaagaaggaatgggttgacaaacttagtgaagtttctctcagctctgatgcc
ttctttcctttcagggataatgtagacagagctaaaaggagcggtgtggcctacattgct
gctccttctggttctgctgctgacaaagttgtgattgaggcttgcgatgaattgggaata
atccttgctcatacgaatcttcggctctttcatcactga
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