Mycobacterium tuberculosis H37Ra: MRA_1571
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Entry
MRA_1571 CDS
T00540
Symbol
ilvA
Name
(GenBank) threonine dehydratase
KO
K01754
threonine dehydratase [EC:
4.3.1.19
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00260
Glycine, serine and threonine metabolism
mra00290
Valine, leucine and isoleucine biosynthesis
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01200
Carbon metabolism
mra01230
Biosynthesis of amino acids
Module
mra_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MRA_1571 (ilvA)
00290 Valine, leucine and isoleucine biosynthesis
MRA_1571 (ilvA)
Enzymes [BR:
mra01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.19 threonine ammonia-lyase
MRA_1571 (ilvA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PALP
Thr_dehydrat_C
Motif
Other DBs
NCBI-ProteinID:
ABQ73316
UniProt:
A5U2R6
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All DBs
Position
1764945..1766234
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AA seq
429 aa
AA seq
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MSAELSQSPSSSPLFSLSGADIDRAAKRIAPVVTPTPLQPSDRLSAITGATVYLKREDLQ
TVRSYKLRGAYNLLVQLSDEELAAGVVCSSAGNHAQGFAYACRCLGVHGRVYVPAKTPKQ
KRDRIRYHGGEFIDLIVGGSTYDLAAAAALEDVERTGATLVPPFDDLRTIAGQGTIAVEV
LGQLEDEPDLVVVPVGGGGCIAGITTYLAERTTNTAVLGVEPAGAAAMMAALAAGEPVTL
DHVDQFVDGAAVNRAGTLTYAALAAAGDMVSLTTVDEGAVCTAMLDLYQNEGIIAEPAGA
LSVAGLLEADIEPGSTVVCLISGGNNDVSRYGEVLERSLVHLGLKHYFLVDFPQEPGALR
RFLDDVLGPNDDITLFEYVKRNNRETGEALVGIELGSAADLDGLLARMRATDIHVEALEP
GSPAYRYLL
NT seq
1290 nt
NT seq
+upstream
nt +downstream
nt
gtgtccgccgaactgagccagagcccgagcagctcgccgctgttttcactatctggggca
gacatcgaccgtgccgccaagcggatcgcaccggtagtcacgcccaccccgttgcaacct
agcgatcggttgtcggcgatcactggcgccacggtctacctcaagcgcgaagacttgcag
acggtgcgctcttataagctacgcggagcgtacaacctgttggtgcagttgtccgatgag
gaactggccgcgggcgtggtgtgttcttctgcgggcaaccacgcgcagggcttcgcgtat
gcgtgtcgctgtctgggtgtgcacggccgggtctacgtacctgccaaaacccccaagcag
aagcgtgaccggatccgctaccacggcggggagttcatcgacctgatcgtgggtgggtcg
acctatgatctggctgcggcggcggcccttgaggacgtggaacgcaccggggccacgctg
gtaccgccgtttgacgacctgcgcaccatcgccggccagggcacgatagccgtcgaagtg
cttggccagctcgaggacgagccggacctggtggtggtcccggtgggtggcggcggctgc
atcgcggggatcaccacctacctggccgagcggacgaccaacaccgcggtgctgggcgtc
gagccggctggtgcggccgccatgatggccgcgctcgcggcgggcgagccggtgacgctg
gaccatgtcgaccagttcgtcgacggcgccgcggtgaaccgggcgggcacgctgacctat
gccgcgctagccgccgccggcgacatggtttcgctcaccaccgtcgacgagggtgcggtg
tgcacggcgatgctcgatctgtatcagaacgagggcatcatcgccgaaccggccggtgcc
ctgtcggtcgccggtctgttggaagccgacatcgagcccgggtccaccgtggtgtgcctg
atttcgggcggcaacaacgacgtgtcccgttacggggaggtgttggagcgctcgctggtc
cacctgggcctcaagcactatttcctggtcgacttcccgcaggagcccggtgcgctgcgc
cggtttctcgacgacgtgctcggacccaacgacgacatcaccttgttcgagtacgtcaag
cgcaacaaccgggagaccggtgaggcgctggtgggtatcgagctgggatcggccgcggat
ctagacggtctgctggcccggatgcgggcgaccgacattcacgtcgaggcgttggaaccg
gggtcgccggcttaccgctatctgctgtag
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