Methylobacterium radiotolerans: Mrad2831_2361
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Entry
Mrad2831_2361 CDS
T00674
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mrd
Methylobacterium radiotolerans
Pathway
mrd00300
Lysine biosynthesis
mrd00550
Peptidoglycan biosynthesis
mrd01100
Metabolic pathways
mrd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mrd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Mrad2831_2361
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Mrad2831_2361
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Mrad2831_2361
Enzymes [BR:
mrd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Mrad2831_2361
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ACB24356
UniProt:
B1LXZ9
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All DBs
Position
complement(2499495..2500943)
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AA seq
482 aa
AA seq
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MTALWTREELESATGGCLTGAERAISGASIDTRTLQPGDLFFAIRGDARDGHDFVPDALG
RGAGAAVVSAARAEALAAHGPVLAVPEGGADPVLTAMVRLGAAARARTSAQVVAVTGSVG
KTGTKEALRHVLSEQGETHASAASYNNHWGVPLTLTRMPRSARYGVFEIGMNHGAEIVPL
TAQVRPDIALITTIAPAHIEHFASLAAIADAKGEIFSGLRPGGVAILNRDAPHFDRLAAH
AQASRAGRVVTFGEHPDADVRALKIVLRPDLSVIDAAVMGQPVTYKLGTAGRHAALNSLG
VMAVVHSLGADLARAALSLGGLTPPAGRGERTALEIGGGTAYLVDESYNANPVAVRAALA
TLAGIETGPRGRRIAVLGDMLELGAAAPDLHRGLAEAIEAARVDLVFTAGPLMRNLFEAL
PVSRRGAVADTAADLLEPLARTLRSGDAVMVKGSNGSRMGRIVEALKARYAVDPARRTQA
AP
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcactctggacgcgggaggagctggaatccgcgacgggcggctgcctgaccggc
gccgagcgcgccatctcgggcgcctcgatcgacacccgcacgctccagcccggcgacctg
ttcttcgcgatccgcggcgatgcccgcgacggccacgacttcgtccccgacgccctgggg
cgcggggccggtgccgcggtggtgagcgccgcgcgcgccgaggcgctcgccgcccacggc
cccgtcctggcggtgcccgaggggggcgccgacccggtcctgaccgccatggtgcggctc
ggcgccgccgcccgggcccggacgtccgcgcaggtcgtggcggtcaccggctcggtcggc
aagaccgggaccaaggaagcgttgcgccacgtcctgtccgagcagggcgagactcacgcc
tcggcggcctcctacaacaaccactggggcgtgcccctgaccctgacgcggatgccgcgc
tccgcgcgctacggcgtgttcgagatcggcatgaaccacggcgccgagatcgtgccgctg
accgcccaggtccggccggacatcgcgctgatcaccacgatcgcgcccgcccatatcgag
cacttcgcctcgctcgccgcgatcgcggacgccaagggcgagatcttctccggcctccgg
cccggcggggtggcgatcctgaaccgcgacgccccgcatttcgaccggctggccgcccac
gcccaggcctcccgggcgggccgggtggtgaccttcggcgagcacccggatgccgatgtc
cgcgccctgaagatcgtgctccggcccgacctgtcggtgatcgacgcggcggtgatgggc
cagcccgtcacctacaagctcggcacggccggccggcacgcggcgctgaactcgctgggc
gtcatggcggtggtccacagcctcggggccgacctcgcccgcgcggccctgtcgctcggc
gggctgacgcctccggcggggcgcggcgagcgcaccgccctcgagatcggcggcggcacc
gcctacctcgtggacgagagctacaacgccaatcccgtcgcggtccgcgcggcgctggcg
accctggcggggatcgagaccgggccccgcggccgccggatcgcggtgctgggcgacatg
ctggagctcggcgccgccgcgcccgacctgcatcgcggcctggcggaggcgatcgaggcg
gcccgggtcgacctggtcttcacggccggtccgctcatgcgcaacctgttcgaggccctt
ccggtgagccgccgcggcgcggtggccgacaccgcggccgacctgctcgagccgctcgcc
cggaccctgcggtccggcgacgccgtcatggtgaagggatcgaacggcagccgcatgggc
cggattgtcgaggcgctgaaagcccgctacgcggtcgatccggcccggcggacccaggcc
gccccgtga
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