KEGG   Mycobacterium saskatchewanense: MSAS_52440
Entry
MSAS_52440        CDS       T07413                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase subunit alpha
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
msak  Mycobacterium saskatchewanense
Pathway
msak00230  Purine metabolism
msak00240  Pyrimidine metabolism
msak01100  Metabolic pathways
msak01232  Nucleotide metabolism
Module
msak_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
msak_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:msak00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    MSAS_52440 (nrdE)
   00240 Pyrimidine metabolism
    MSAS_52440 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:msak03400]
    MSAS_52440 (nrdE)
Enzymes [BR:msak01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     MSAS_52440 (nrdE)
DNA repair and recombination proteins [BR:msak03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    MSAS_52440 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-ProteinID: BBX66070
LinkDB
Position
5541311..5543476
AA seq 721 aa
MPPTVAAEPVTSGAHALPGETDYHALNAMLNLYDADGKIQFDKDVLAAREYFLQHVNQNT
VFFHNYDEKLDYLIRENYYEREVLDQYSRNFVKSLVERAYAKKFRFPTFLGAFKYYTSYT
LKTFDGKRYLERFEDRVCMVALTLAAGDTGLAEKLVDEIIEGRFQPATPTFLNSGKKQRG
EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNIREHGAPIKNIENQSSGVIP
IMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIP
DITFELAKKNEDMYLFSPYDVERVYGVPFADISVTEKYYEMLDDARIRKTKIKAREFFQT
LAELQFESGYPYIMFEDTVNRANPIEGKITHSNLCSEILQVSTPSLFNEDLSYAKVGKDI
SCNLGSMNIAKTMDSPDFAHTIEVAIRGLTAVSDQTHISSVPSIEHGNNESHAIGLGQMN
LHGYLAREHIFYGSEEGIDFTNIYFYTVLYHALRASNRIAIERGTHFTGFEKSKYASGEF
FDKYTEQVWEPKTDKVRQLFADADIRIPTQDDWRRLKESVRAHGIYNQNLQAVPPTGSIS
YINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNENLEYYQDAYEIGYEKIIDTYAAA
TQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCM
L
NT seq 2166 nt   +upstreamnt  +downstreamnt
gtgccaccaaccgtcgctgcagagcctgtaacgtccggcgcccacgcgctgccgggggag
acggactaccacgcgctcaacgccatgctgaatctgtacgacgcggacggcaagattcag
ttcgacaaggacgtccttgccgcgcgcgagtacttcctgcagcacgtcaaccagaacacg
gtcttcttccacaactacgacgagaagctcgactatctcatccgcgaaaactattacgag
cgtgaggttctcgaccaatactcgcgcaacttcgtcaagtccctggtggaacgcgcctac
gccaagaagttccggttcccgacgttcctcggcgcgttcaagtactacacctcgtacacg
ctgaagaccttcgacggcaagcgctacctggagcggttcgaggaccgggtgtgcatggtc
gcgctgacgttggcggccggtgacaccgggctggccgagaagctggtcgacgagatcatc
gaggggcgattccagccggccaccccgacgtttctgaactcgggcaagaagcagcgcggc
gaaccggtgagctgctttttgcttcgcatcgaggacaacatggagtcgatcgggcggtcg
atcaactcagcgttgcagctgtccaagcgcggcgggggagttgcgttgctgctgagcaac
attcgggaacacggcgcccccatcaagaacatcgagaaccagtcttcgggagtcatcccg
atcatgaagctgctggaggactccttctcctacgcgaatcagctgggggcgcgccagggc
gccggcgcggtgtacctgcacgcccaccaccccgacatctaccgcttcctggacaccaag
cgggagaacgccgacgagaagatccggatcaagacgctgagcctcggcgtggtgattccc
gacatcaccttcgagctggcaaaaaagaacgaggacatgtacctgttctcgccgtacgac
gtcgagcgcgtgtacggcgtgccgttcgccgacatctcggtgaccgagaagtactacgag
atgctcgacgacgcccggatccgcaagaccaagatcaaggcgcgggagttcttccagacg
ttggccgagctgcagttcgagtccggctacccgtacatcatgttcgaggacacggtgaac
cgggctaatcccatcgaaggcaagatcacgcactcgaacctgtgctcggagatcctgcag
gtgtccacgccgtctctgttcaacgaagacctctcgtatgccaaggtgggcaaagacatt
tcgtgcaacctcgggtcgatgaacatcgccaagacgatggactcgccggacttcgcccac
acgatcgaggtggcgatccgggggctgaccgccgtcagcgaccagacgcacatctcatcc
gttccctcgatcgagcacggcaacaacgagtcccacgcgatcggactcggccagatgaac
ctgcatggctacctggcccgcgagcacatcttctacggctccgaagagggcatcgacttc
accaacatctacttctacaccgtgctctaccacgcgctgcgggcctccaaccgcatcgcg
atcgaacgcggcacgcatttcacgggtttcgagaagtccaaatacgcgtcgggggagttc
ttcgacaagtacaccgagcaggtgtgggagcccaagacagacaaggtgcgtcaactcttc
gccgacgccgacatccgcattccgacgcaggacgattggcgccggctcaaggaatcggtg
cgggcgcatggcatctacaaccagaacctgcaggccgtgccgccgaccgggtcgatctcc
tacatcaaccactcgaccagttcgatccaccccatcgtgtccaaggtcgagatccgcaag
gagggcaagatcgggcgggtctactacccggcgccctacatgaccaacgagaacctggag
tactaccaagacgcctacgagatcggctacgagaagatcatcgacacctacgccgcggcc
acacagcacgtggaccaggggctgagcctgacgctgttcttcaaggacaccgcgaccacc
cgcgacgtgaacaaggcgcagatctacgcctggcgcaagggaatcaagacgctgtactac
atccggctgcggcagatggcgctggaaggcaccgaggtcgagggctgcgtgtcctgcatg
ctgtga

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