Micropterus salmoides (largemouth bass): 119908509 Help Entry 119908509         CDS       T07309                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism msam  Micropterus salmoides (largemouth bass) Pathway msam04020   Calcium signaling pathway msam04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:msam00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     119908509 (ryr3)    04020 Calcium signaling pathway     119908509 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:msam04040]     119908509 (ryr3) Ion channels [BR:msam04040]  Voltage-gated cation channels   Ryanodine receptor    119908509 (ryr3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 Med16_bridge Motif Other DBs NCBI-GeneID:  119908509 NCBI-ProteinID:  XP_038582168 LinkDB All DBs Position Unknown AA seq 4847 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVATIQKEHRKFCLAAEGLGNRLCYLESTSEAKYVPP DLCICNFVLEQSLSVRALQEMLANTGQNSEGGQGGGHRTLLYGHAILLRHSFSNMYLTCL KTSRSLTDKLSFDVGLQEDSIGEACWWTIHPASKQRSEGEKVRIGDDMILVSVSTERYLH LSISNGNIQVDASFMQTLWNIQPTCSSGNMAVGFLIGGHVMRLCHGHDESLTIPGADKST EEQRIVNYEAGKGASKARSLWRLEPLRISWSGSHIRWGQAFRLRHLSTGHYLALTEDRGL ILQDREKSDTTATAFCFRPSKEKSDMGPKRDIDGMGVPEIKYGDSVCFIMHMATGLWLSY LAPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESRAARIIRNTTFLFANFIKALD RIAEGETTAVAGYVEEVLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQDLFKEEGML SLLSKCIDRMNVYNSAAHFGEMAGEEAGAAWKDILNLLYELLAALIRGNRNNCTQFSRNL DWLVSKLERLESSSGILEVLHCILVESPEALNIIQRAHIKSIISLLYKHGRNHKILDVLC SLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGVADGSAQYKKWYF ELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSFDGLHLWSG RIPRAVASINQHLLNSDDVISCCLDLGAPSMSFRINGQPVQGMFEDFNTDGFFFPVVSFS AGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVKEYKRDYEGVRDLLGTTQ FLSQASFIPTPVDTSQIVLPPHLDNVRDKLAENIHELWGMNKIELGWTYGKVRDDNKRQH PCLVDFTKLPETERNYNLQMSSETLKTLLALGCHVAQVNVHAEEDLKRIKLPKDYMMSNG YKPAPLELSDVKLTAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSRRNPRLVPY ALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEGAHMLDDQSIETTRLFRVEQTYAVK TGRWYFEFEAVTGGDMRVGWARPGCRPDVELGGDDQAFVFDGYRARRMHAGSRYFGLTWK KGDVVGCMINMEDKSMIFTLNGELLITNKGSELCFTDFETEDGFIPVCSLGMSQIGRMNL GKDASTLKYYTMCGLQEGFEPFAVNMNRDIIMWFSKRLPTFVNVPQDHMHIEVTRIDGTI DSPPCLKVTHKTFGTQNSNNDMVYCRLSMPVEFYSVDKLLDESLKLSHPPKEDGTVDYGS ITTYYHAVRVFAGQDPASVWVGWVTPDYHYHSKNFGLSKTRTVTVTLGDERGRVHESVQR SNCYMVCGADVAGLSSSSRSTSDLEIGCLVDLATGLVSFTANGKEMSTTYQVEPNTKLFP AVFVRPTSANLFQMEFVKIKDAMPLSSAIFKSEHRNPVPQCPPRLDVQTIVAVLWSRMPN TFLNVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDILELSEHEDLKKFHYHTLKLY CALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGLLREGFYNVLISIHLETAKEARLMM NNEFIIPVTDETRSIKLFPDESKRHSLPGVGLSTSLKPRVNFSPVGIINTKHHQYLYSPQ IPLGILKEKAISMLTEAVQGGGTHIRDPVGGSVEYQFVPILKLIGTLLIMGVLTSEEVRL ILLLIDPNVFGEAKEGEEVKGDEVAVGGEKEEVSKNEEKAVEAGEEETKECKPPVKGLLE KSLPESVKRQMCELLHYFCDCELKHRIEAIVSFSDSFVSKLQFNQKFRYNELMLAFNMSA AVTAKKTKEFRSPPQEQINILLNFSAGEDCPCPEEIQDELNSFHEELRLHCGIPVEEDEE EQDTSIKGRLLALLYKIKGPPHKTEEEPTEKEQAAPTNLKELISQTITSWAQESHIQDPE LVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAVNLLVSLGQIRSLLSVRMGKEEE KLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMQVMVNVLGGDKSQEIAFPKMVASCCRF LCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNNGLALALEE PDLEKVVTYLAGCGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFAVFCNGESVEENANV VVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPALDLPAGLPAGSGDEEGEIIHM GNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTTDLVGIISIPLKMPV VNKDGTVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLQMLEVGFLPDLQASASLDT EVLSTTETALAMNRYIGSALLPLLTRCAALFASTEHYAHLIDSTLHTIYRLSKGRSLTKA QRDAIEECLLAICKHLRPSMMQQLLRRLVFDVPMLSEYCIIPLRLLTNHYEQNWKYYCMP SGMGSFGMASEEELLLTKKLFWGIFDSLSHKKYDAELFKMAMSCLCAIAGALPPDFVDAS PGATLEKQAPMDAQGNFDPKPINTTNISLPEKLEYIANKYAEHSHDKWSSEKVSAGWKHG DSVDEQAKSHPLLKPYKALSEKERETYRWPVRESLKSMLAMGWNIERTKEGEAMFQQRES ENNERPLSLSRQTTYRPVNGFSPPMDLHNVTLSRELQGMVEVVAENYHNIWAKKKKTELV SKGGGTHALLVPYDTLTAKEKYRDKEKAQDLIKFLQISGYAITRGLKDMEQDSSSMEKRF CFKFLKRLLKYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPMTDQTLKNHCL YFLSTPSKNMSSCGCASNKEKEMVTSLFCKLAALVRHRISLFGSDSAIMVSCLHILTHSL DTRTVMKSGSELVKAGFRAFFENAAEDLEKLLEMLKLGKFMQSRAQMKSVTQSINYVTVA LLPILTALFEHIKTHEFGTDLLLDDVQLSCYRILTCFYSLGTGKNVFVERHLPALGESLA TLVGAMPVAFLEPDLNAHNPLSVFNTKTPRERAILSMPDTVEEMCPEMPRLDRLLKDVND VSESGARYSDVPQVIEVILPMLCNYLSYWWEKGPENWPPGTHCCTMVTSEHLSSILGNIL KILNNNLGIDDAPWMKRIAVYSQPIICKAGADLLRTHFLPTLDKLKKKTVKVVAEEELLK ADGKGDNQEAELLILDDFAVLCRDLYAFYPMLISYVDNNRSRWLKEPDADSTELFRMVAE IFILWCKSHNFKREEQNFVVQNEINNLGFLTGEGKTKMSKSGGDQERKHKRRRGEYYSIQ TSLIVAALKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKEHLRQNLHLQDKSDDP AVQWQLNLYKDVVVKSEEPANPEHTVDRVQSISAAVFHLEQVEQPLRNKKCVWHKLLSKQ RKRAVVACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEKLVQDLAKTPMKIVEE EEEEVAEVQPDPLHQLILHFSHNALTERSHLEEDPLYIAYADMMAKSCAEDEEEEEEEGK EKTFEEKEMEKQKTLYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKLGISILNGGN VQVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSSSKVL QNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYW YYSGKDVIDETGKVNFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHV FANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSNNV EMILKFFDMFLKLKDMTTSDNFREYDPDFKGIISKKEFQKSMESQKQYNQSEIEFLLSCA EADENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLATFLDLAESVLSYFE PYLGRIEIMGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEGGESEKMEMFV NFCEDTIFEMQLASQISEPDVTEQPEEEEEEEAHSILEELAGEEEGALESASAFTTACRS VKKKIGSVRQAFSVKNMRKQFKKIKKLSIKEIITGFFSFFWMLFIGFFKGIYGLIFGFFH VIWSSMFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDAIEVEKVEAIESSGSLDIAMTP AGDKGEVDMMLEMLTVPKREGGKHAEPGLGDVSELSAETSTTDHKKKAAAKPDETPENQP EKADTENQEKEDKPKEEEEAAKEPVTEEKPKTRSSQPKEAAPAFMSSIFALLDVYLTKML NYLARNFYNLRFLALFVCFAINFILLFYKVTGESEEEIDQENRWGGDEEDDVDTLFDMDE FVLQESSGYMLPTLRFLAIFHTVISLVCLFGYYCLKVPLVVFKREKEIARKLEFDGLYIT EQPSDDDIKGQWDRLVINTPSFPSNYWDKFIKRKVINKYGDLYGAERIAELLGLDKSALD FDPTVETVEKEASLLSWLSSIDTKYHIWKLGVVLTDNYFLYLIWYTTMSIFGHFNNFFFA AHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDED EPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDITFFFFVIVILLA IIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNLANYLF FLMYLINKDETEHTGQESFVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14544 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaagatgagatccagttcttgagaactgatgacgaggtg gtgctccagtgtgtggccaccatccagaaggagcatcgcaagttttgcctggccgctgag ggacttggaaaccgtctgtgttacctggaatccacatctgaagctaagtatgttcctcca gacctgtgtatttgtaactttgtgttggagcagtccctgtcagtgcgggccctgcaggag atgctggctaacactgggcagaacagcgaaggggggcaagggggtggacatcggaccctg ctctacggtcatgccatcctccttcgccactccttcagtaatatgtacctgacctgtttg aagacatcaaggtctctgacagacaagctgtcatttgatgtcgggctacaagaagattca ataggagaggcctgctggtggaccatacaccctgcatccaagcagagatctgagggagag aaagtccgcatcggagacgacatgattcttgtcagtgtgtcgacagagagatacctgcac ctctctatctccaatggcaacatccaggttgatgcctccttcatgcagaccctgtggaac atccagcctacctgctcttcaggcaacatggctgtagggtttttgattggtggacatgtg atgcgtctttgtcatgggcatgatgagagcttgaccatccctggagcagacaagagtaca gaggagcagaggatagtcaactatgaggcgggtaagggagcatcaaaggcccgctcactt tggagactggagcctctcaggatcagctggagcggtagccacattcgctggggtcaggcc ttccgactacgccacctctctactggccattacctggcactgactgaggaccgcggcctg atcctgcaggacagggagaagtccgacaccacagccactgccttctgcttcaggccatcc aaggaaaagagcgacatgggccctaagagggacattgacggcatgggagttccagagatc aagtacggagactctgtctgcttcatcatgcatatggcaacaggactgtggctgtcttac ctggcgcctgatgccaaatcgtctcgcctgggacccctgaaaagaagggcctgcctgcat tctgaaggccacatggatgatgggcttatcctgcagcgctgtcagcatgaggagtctcgt gctgctcgtatcatccgcaacaccacgttcctcttcgccaactttatcaaggctttggac agaattgctgagggtgagaccaccgcagtggctgggtatgttgaagaggtgctgcagacg ctgaacgacctgatcgagtacttcaaacagcccgattcagagctagagcacgaggagaaa cagtgtcttcttcgttcactcatcaaacgtcaagacctcttcaaggaggagggcatgttg agcctcctgtccaaatgcattgaccggatgaacgtgtacaacagtgctgcccattttgga gagatggctggggaggaagcaggcgcagcatggaaagacattctcaaccttctctatgaa ctcttggctgcactgattcgcgggaacagaaacaactgcacccagttctcccgcaacttg gactggttggtcagcaaactggagagactggaatcttcatcaggcatcctggaagtcctc cactgtatcttggtggaaagtccagaggccctgaacatcattcagagagctcacattaaa tccataatctctttgctctacaagcatggacgcaaccacaagattctggatgtcctgtgt tcactctgtgtttgtaatggagtagcagtgagagccaatcagaatctgatctgtgacaac ctgcttcccaagagggacctgctgcttcagactcgactggtcaatgatgttcaaagtatg aggccaaacatcttcctgggcgtggctgacggttcagctcagtataagaagtggtatttt gagctggtgattgatcaggtggaccactttgtaacgggagagccgacccacctgagggta ggctgggccaacactaaaggctacgctccgtaccccggtggaggagagggatgggggggc aacggtgtcggggatgacctgtactcttacagctttgatggacttcatctctggtcaggc cgaatcccgagggccgtggcctccattaaccagcacctgctgaactcagacgatgtgatt agctgctgtctggatttgggcgctcccagcatgtccttcaggatcaacggtcagcctgtc cagggcatgttcgaggacttcaacaccgatggattcttcttccccgtcgtcagcttctct gcaggtgtcaaggttcgttttctgttgggtggacgccatggagatttcaagttcctgcca cccgctggttactctccgtgctacgaggctctcttgcccaaagagaaaatgcatgtagag cctgtgaaggagtacaagagagactacgagggggtccgtgacctgctgggaaccacccag ttcctctctcaggcctcattcatccccactcctgttgacaccagccagattgttcttccc cctcacctggacaacgtccgagacaagctggcagaaaacatccacgaactgtgggggatg aacaagattgaactgggctggacctatggcaaggttcgtgatgacaacaagaggcagcac ccttgccttgtagatttcaccaagctgcccgaaactgaaaggaactacaacctgcagatg tccagtgaaactcttaagaccctgttggctcttggatgccatgttgcccaggtcaatgtt cacgctgaggaagatctgaagagaatcaaacttcccaaagactacatgatgtctaatggt tacaagcctgcgccactggagctctctgacgtgaaactgactgcaggtcaggaggttcta gttgataaactggccgagaatgcacacaatgtgtgggccaaagacagaattaaacaagga tggacctatggcatccagcaggatttgaagagcaggcgtaatcctcgcctggtgccatat gctttattggacgagcgcactaagaaatctaacagagacagtctcagagaggccatcagg accatggttggatatggatatgacatcgaccccccagaccaggagggcgcccatatgctg gatgatcagagcatcgagaccacccgcctcttccgcgtggagcagacatatgcagtgaag acgggaaggtggtactttgagtttgaggctgtgactggaggtgatatgagggttggctgg gccagaccaggctgcaggcccgatgtggaactgggaggggatgaccaggcctttgtcttc gatggatacagggctcgacgtatgcacgcaggcagccgctactttggacttacttggaaa aagggcgacgtggttggttgcatgatcaacatggaggacaaatccatgattttcaccttg aacggagagctcctgatcaccaacaagggctctgagctttgcttcaccgactttgagaca gaggatggtttcatccctgtgtgcagtctgggcatgtctcagatcggacgtatgaacctg ggcaaggacgccagcactttaaagtactacaccatgtgtggtctccaggaaggttttgaa ccctttgctgtcaacatgaacagagacatcatcatgtggttcagcaagcgccttcccaca tttgtcaacgtaccccaggaccacatgcatatcgaggtgacgaggattgatggaactata gacagccctccctgcctcaaggtcacacataagacttttggcacacagaacagcaacaat gacatggtctactgtagactgagcatgcctgtggagttctactctgtagacaagttactg gatgaatcactgaaactcagccatcctccaaaagaagatggaactgttgactacggaagc ataacaacttactaccatgcagtgagagtgtttgccgggcaggaccctgcgtcagtgtgg gtgggctgggtaactccggactatcattaccatagcaagaacttcggcctcagcaagaca cgaaccgtcacagtcaccctgggagatgaaaggggccgggtccatgagagcgtccaaagg agtaactgctacatggtgtgtggagcggatgttgccggcctgtcctcctccagccgctcc acctctgacctggagatcggctgtctggtcgacctggccactggccttgtctctttcact gccaatggcaaggagatgtccacaacatatcaggttgagccaaataccaagctcttccca gcggtgtttgtacgccccactagtgcaaacctcttccagatggaatttgtcaagatcaag gatgcaatgccgctctcgtctgccatatttaagagcgagcacaggaacccagtgccgcag tgcccgccacgactggatgtgcagactattgtggccgtgctgtggagccggatgccaaac accttcctcaatgtggagactgctcgggtcagcgagaggcacggctgggtggtccagtgt ctggaaccgctgcagatgatggccgtacatatccctgaggagaacaggtgtttggacatc ctggagttatctgagcatgaagacctgaaaaaattccactaccacacactgaagctgtac tgtgccctctgtgccctgggaaacacccgcgttgctcacgccctctgcagccacttggac cagtcacagctcctctacaccatcgacaaccagtacctgtctggcctgctgagagagggc ttctacaatgtcttgatcagcatccatcttgagacagcaaaggaggctcgcctgatgatg aacaacgagttcatcatccctgtgacggatgagactcgctccatcaagttgttccctgac gagtccaagcggcactcgctgcctggcgttggcctgagcacctcactcaaacctcgggtc aacttctcccccgtcggcatcatcaacacaaagcaccaccagtacctctacagcccccag atccctctgggcatccttaaagagaaagccatcagcatgctcactgaggctgtgcagggt ggaggcacgcacattcgagacccagtaggcggcagtgtggagtaccagttcgtccccatc ctgaagctgattggaacgctgttaatcatgggagtcctaaccagtgaagaggtgagactg attctcctcctgattgatcccaacgtgttcggagaggccaaggagggtgaagaggtcaag ggggatgaagtggctgtcggaggggagaaagaggaagtgagcaagaacgaggagaaagcc gtggaggcgggagaggaggagacaaaagaatgcaaaccgccagttaaaggtctgctggag aagtcactgcccgagtctgtcaaacgccagatgtgcgagctgctgcactacttctgcgac tgtgagctgaagcaccgcatcgaggccattgtctccttctccgacagcttcgtgtctaag ttgcagttcaaccagaagttccgctacaatgagctgatgctggcgttcaacatgtccgcc gccgtcaccgccaagaagactaaagagtttcgatcacccccacaggagcagatcaacatc ctgttgaatttcagtgcaggggaggactgcccctgtcccgaggagatccaggacgaactc aactccttccatgaagaactgcgactgcactgtggaattcccgtggaggaggacgaggaa gagcaggacacatcaataaaaggccgtcttctcgctttactctacaagatcaaaggtccg ccccataagacagaggaggaacccacagagaaggaacaggctgctccaaccaacctgaag gagctgatctcccagaccataaccagctgggctcaggagtctcacatccaggacccagag ctggttagagtgatgttcagcctgctaaggaggcagtatgacggcatcggcgagctgctc cgggctatgaagaaatcctacaccatcagtgccgcgtctgtgcaggatgctgttaacctg ttggtatctcttggtcagataaggtctctcctgtcagtacgcatgggcaaggaggaggag aaactcatgattgatggccttggtgacatcatgaacaacaaggttttctaccaacatccc aacctaatgagagtgctgggcatgcatgagactgtcatgcaggtcatggtcaacgtactg ggaggagacaagtcacaggagattgccttccccaagatggtggccagctgttgtcgtttc ttgtgctacttctgtcgcattagccgccagaaccagaaagccatgtttgaccacctgagc tacctgctggagaacagcagtgtcgggctggcctctgaagctatgcggggctccacccca ttggatgttgcagcatcttcagtgatggacaacaacggcctggctctggccctggaggaa cctgatctggagaaggtggtgacatacctggcaggctgcggtcttcagagttgtgccatg ctagttgcaaaaggttacccagaccttggctggaaccctatagaaggagagcgttacctg tccttcttgagattcgccgtcttctgcaatggtgagagtgtggaggaaaatgccaacgtg gtggtgaagctgctgatcagacgtccagagtgtttcggccccgccctgaggggagaggga ggtcaaggtctgctggccgccatgaaggaggccatcaagatctctgaggatcctgccctg gacctgcctgctggacttcctgctgggtctggtgatgaagaaggagaaattattcacatg ggtaacgccatcatgtccttctactcagctctcattgacctgctgggacgctgtgctcca gagatgcatctcatcaatgcaggcaaaggtgaggcgctacgtatccgggccatcttgcga tcgttggttcccactacagacctggtgggcatcatcagcatcccccttaaaatgcctgtg gttaataaagatggcacagtgacagagcccgacatgtcagcctgtttctgtccggaccac aaggcccccatggtgctcttcctggatcgagtctacggcatcgaggaccagagcttcctt ctccagatgttggaggtcggcttcctgcctgacctccaagcctctgcatctctggacaca gaggttttgagcaccactgagactgcactggccatgaacaggtacatcggctcggccctg ctgcctctgctgacccgctgtgcagctctgtttgccagcacagagcactacgcacacctg attgactccacgctgcacactatctaccggctgtctaaaggccgctcactcacaaaagcc caaagggacgccatcgaggagtgtctgctggctatctgcaagcatctgcgtccctctatg atgcagcagctgctcagacggctggtgttcgacgttcccatgctctcggaatactgcata attcctctccggcttctgaccaaccactatgagcagaactggaagtactactgcatgcct tctggtatgggcagctttggaatggcctccgaggaagagctcctcctaacaaagaaactc ttctggggaatcttcgactccctttctcacaagaagtatgatgccgaacttttcaaaatg gcaatgtcatgcttgtgtgccattgctggagccttgcctccagactttgtggatgccagt cctggagcaacactggagaaacaggcaccaatggacgcacagggcaactttgatcccaaa cccatcaacactaccaatatctcccttcctgaaaaacttgagtacatcgccaacaaatat gcagagcattcccatgacaagtggtcctcagagaaggtgtcagcaggctggaaacatgga gacagtgtggatgagcaggccaaatcccatccactgctgaagccttacaaagcgctgagt gagaaggagagagaaacataccgctggccagtgagggagtcattgaagagcatgctggct atgggctggaacattgagaggaccaaggagggagaagccatgttccaacaacgagagagc gaaaacaacgaaagacctctgagtctcagtaggcagactacttatcgccctgttaatgga ttcagtcctccaatggacttgcacaatgtcaccttgtctagagagttacagggcatggtg gaggtggttgcagaaaattaccacaacatctgggccaagaagaagaaaaccgagctcgtt agtaaaggaggagggacccatgcgctgctggttccctatgacaccctgacagctaaagag aagtacagagacaaggaaaaggcccaggatctcatcaagtttctgcagattagtggctat gccatcacaagaggcctgaaggacatggagcaagactcatcatccatggagaagcgtttt tgcttcaaattcctcaaaaggctgttgaaatatgttgactccgcccaggagttcatcgct catcttgaggctatggccaccagtgggaagacagacaaatcaccccatgaccaggaaatc aagttctttgcaaaggttttgcttcctatgacagatcaaactttaaagaaccactgtctc tacttcctgtccacccccagcaagaacatgagcagctgtggctgtgcctccaacaaagag aaggagatggtcaccagcttgttctgtaagctggcagctcttgtcagacacaggatttct ctctttggaagtgactctgcgattatggtgagctgtttgcacatcctcactcactcactt gacaccagaacggtgatgaagtctggctcagagctggtcaaagccggctttcgggctttc tttgagaacgcagcggaggacctagagaagctgctggagatgcttaaactggggaagttc atgcagtcccgtgcccagatgaagagtgtcacccagagcatcaactatgtgactgtggcg ctgctgcccatcctcactgccctgtttgagcacatcaagacgcatgagtttggaacggac ctgctgttggatgatgtgcagctttcctgctatcgaatcttgacctgtttctactctctg ggaacaggaaagaatgtctttgtggagaggcatcttccagctttgggggagagcctggcg accttagtgggagccatgcctgtggcattcctggagcctgacctaaacgctcacaacccg ctctctgtcttcaacaccaagacgccccgagagagagctatcctcagtatgcctgacacc gtggaggagatgtgtccagagatgcctcgtcttgacagactgctgaaagatgtcaatgat gtatcagagtctggcgctcgctacagtgacgtgcctcaggtcattgaggtgatccttccc atgctgtgtaactatctgtcgtactggtgggagaaaggtccagagaactggcctccgggt acccattgttgcactatggtgacctcagaacacctcagcagcatcctgggaaacatcctc aagatcctcaacaacaacctgggcatcgatgacgccccctggatgaagaggattgcagtc tattctcagccaatcatctgcaaggctggagctgatctgctgagaacccacttcctgccc acactggacaaactgaagaagaagacagtgaaggttgtggctgaagaggagctgctgaaa gccgatggtaaaggagacaaccaggaggccgagctgctcatcctggatgattttgctgtg ctctgcagagacctatatgctttctacccaatgctcatcagctatgttgacaacaacagg tccaggtggctgaaggagccggatgcggactccactgagctcttcaggatggtggctgag atcttcatcctctggtgcaagtcccataactttaagcgtgaggagcagaactttgtggtt cagaatgagatcaacaatttgggcttcctgactggagagggcaagacaaagatgtccaag tctgggggggaccaggagaggaaacacaagcgccgtcgaggcgagtactactccatccag acctctctcattgtagctgccctgaagaaaatgctgcctatcggcctcaacatgtgtacc ccaggagatcaggagctcatctcccttgccaagattcgctacagtctgaaagacacagat gatgaggtgaaggagcacttgcgtcagaatctccatctccaggacaaatctgatgaccca gcggtccagtggcagctgaacctgtacaaggacgtggtggtgaagagtgaggaacctgca aacccagaacacaccgtggaccgagtgcagagcatctctgctgcagtcttccacctggag caggtggagcagcctctgagaaataagaagtgtgtgtggcataagcttttgtccaaacag cgtaagcgtgctgtggtggcttgtttccgcatggctccactctacaatctacccaggcat cgcgctatcaacttcttcatcccagcctatcagagactttggatagaagcagaggagtac tcctttgaggagaagctagttcaggatctggcaaaaaccccgatgaaaattgtggaagag gaggaagaggaggtggctgaggtccagccagaccctctccaccaacttattctccacttc agccacaacgctctgacagagagaagtcacttggaagaagatcctttgtatattgcgtat gcagacatgatggcaaagagctgtgcagaggatgaggaggaagaagaggaggaagggaaa gaaaagactttcgaggaaaaggagatggaaaagcagaagaccctgtatcagcaggcgagg ctgcacgcccgtggggccgctgaaatggtgctgcagatgatcagcgccagtaaaggtcgc ctgggccccatggtgacctgcaccctcaaactgggaatctccatcctaaatggaggcaat gtgcaagttcagcagaaaatgcttgattacctaaaagagaaaagagatgcaggctttttc aagagtctctcagggctgatgcagtcttgcagtgtcttggacttgaacgcatttgagagg cagaacaaagcagaaggacttggcatggtgacagaggaaggttcaagttccaaggtgcta cagaatgatgagtttactaaagaccttttccggtttttgcaacttctgtgcgaggggcac aatggagatttccagaacttcttgagaacccaaactggaaacacaaccacagtcaacatc attatcagcactgtggactatctgctccgtcttcaggaatctatcagtgacttctactgg tactactctggaaaagatgtcattgatgagactggaaaagtcaacttctccaaagctcta tctgttgcgaagcagatattcaactcattgactgaatatattcagggcccgtgtattgga aaccagcagagtttagctcacagcagactgtgggatgcagttgtgggtttcttgcatgta tttgccaacatgcaaatgaagctgtctcaggacgccagtcagattgagttgttgaaggag ctgatggatttacagaaggacatggttgtcatgttgctgtctctgctagagggtaatgtg gtgaacggaacaattggaaagcagatggttgacaccctggtggagtcttctaacaatgtg gagatgatccttaagttcttcgatatgttcctcaaactgaaggacatgacgacctctgac aacttcagagagtatgaccctgattttaaaggcattatttcaaaaaaggagttccagaag tcaatggagagccagaagcagtacaaccagtctgagattgaattcctgctctcgtgtgca gaggccgatgagaatgacatgttcaattacaaggagtttgtggagcgattccacgagcct gctaaagatatcggcttcaacgtggcagtgcttctgaccaacctgtctgaacacatgcct cacgactccagacttgccaccttcttagacctggcagagagtgtacttagctactttgag ccttatctgggccgtattgaaatcatgggcagcgcaaagcggatcgagagggtgtacttt gaaatcagcgagtcgagccgcgagcagtgggagaagccgcaggtcaaggagtccaagcgt cagttcatctttgatgtggtcaatgagggtggagagagcgagaagatggagatgtttgtg aatttctgtgaggacaccatttttgaaatgcagctggcctcacagatctccgagccagat gtgactgaacaaccggaggaggaggaagaggaagaagcacacagtatcctggaggagttg gctggagaagaagagggcgccctggaatctgcttcagccttcaccaccgcatgccgctca gtcaagaagaagatcggcagtgttcgccaagccttttctgttaaaaacatgcgcaagcag ttcaagaaaatcaagaagttgagcatcaaggagattatcacaggcttcttctccttcttc tggatgctcttcatcggtttcttcaagggaatctacggcctcatatttgggttcttccat gtcatctggtcctccatgtttggcggcggcctggttgagggagccaaaaacataaaggtg acggacatccttggaaatatgcctgacccgacccagtttggtatccacggagatgcgatt gaagtagagaaagtggaggccatagagtcatcaggaagcttagatatagccatgacacca gcaggcgacaaaggggaggttgacatgatgttggagatgctgacggtgccaaaaagggaa ggaggaaaacatgcggagccaggcctgggtgatgtttctgagttgagtgcagagacctcc actactgatcacaagaagaaagctgccgccaagcccgatgaaacccccgagaaccaacca gagaaagcagacacagagaaccaggagaaggaggataagccaaaggaggaggaggaggcg gctaaggagcctgtgacagaggagaagcccaagaccagatcgagtcagcctaaagaggcg gcgcctgccttcatgtcaagtatctttgctcttctggatgtctatctgaccaagatgctg aactacctggctcgtaacttctacaacctgcgtttccttgctctgtttgtgtgttttgcc atcaactttattcttcttttctacaaggtcactggtgaatctgaagaagaaatagatcag gaaaaccgctggggtggcgatgaggaggatgacgtggacacactcttcgacatggatgaa tttgtcctgcaggagagcagcggctacatgttaccaaccctgcgtttcctggctattttc cacacggtcatctcactcgtctgtttgttcgggtactactgtctgaaggttcctttggtc gtattcaagagggagaaggagattgccaggaagcttgaatttgacggcctctacatcact gaacagccgtccgacgacgacatcaagggccagtgggatcgactcgtcatcaacaccccg tctttccccagcaactactgggacaagtttatcaagcgcaaggtgatcaacaaatatggt gacctgtatggagctgaacgcatcgctgagctcttgggcctggataagagtgccctggac tttgaccccacagtggagactgtagagaaggaagcttccctgctctcatggctgagctcc attgatacaaagtaccatatctggaaactgggcgttgttttgactgacaattacttcctg tatctgatctggtacaccaccatgtccatctttggacacttcaacaacttcttctttgct gctcatcttctggacatcgccatgggcttcaagacccttcgcactatcctgtcttcggtc actcataacggcaagcagcttgtgttgactgtgggtctgctggccgtggtcgtctatctc tacactgtggtggccttcaacttcttcaggaagttctacaataaaagcgaggatgaagac gagcccgacatgaagtgtgatgatatgatgacatgctatttgttccacatgtacgtgggt gtgagagctggaggtggtattggagacgagctggaggacccagctggagacccctatgag ctctaccgcattctgtttgacatcaccttcttcttctttgtcattgttatcctgctggcc atcattcagggtttgatcattgacgcctttggtgagctgagagaccagcaggagcaggtg aaggaggacatggagaccaaatgcttcatctgtggcattgggaatgactactttgatcgg acgcctcacggatttgaaacccacaccttacaagagcacaacctagctaactacctgttc ttcctgatgtacctgattaacaaggacgagactgaacacacgggtcaggagtcattcgtg tggaagatgtaccaggagagatgttgggacttcttccctactggagactgcttccgtaag caatatgaggaccagctgggttag

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