Mycobacterium shinjukuense: MSHI_29270
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Entry
MSHI_29270 CDS
T07415
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mshj
Mycobacterium shinjukuense
Pathway
mshj00860
Porphyrin metabolism
mshj01100
Metabolic pathways
mshj01110
Biosynthesis of secondary metabolites
mshj01120
Microbial metabolism in diverse environments
mshj01240
Biosynthesis of cofactors
Module
mshj_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mshj_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mshj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MSHI_29270 (hemD)
Enzymes [BR:
mshj01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MSHI_29270 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MSHI_29270 (hemD)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBX75021
UniProt:
A0A7I7MS20
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All DBs
Position
complement(3199348..3201057)
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AA seq
569 aa
AA seq
DB search
MTRQPTMRVRKPRPGRITFVGSGPGDPGLLTTRAATVLANAALVFIDPCVPEPVLALIGK
DLPPVSGPAPAAPGSGNADGAIEGDDRGQHPPAVVSGGPDIRPALGDPVEVAKMLTTEAR
AGADVVRLVSGDPLTVDAVIAEVNAVARTHLHIEIVPGLAPSNAVPTYAGLPLGSSHTVA
DVRIDPENTDWEALAAAPGPLILQASAAQLADAARTLIDHQLAETTPCVVTAHGTTCQQR
SLETTLQGLTDPAVLGGADARLSPANGGEPFTGPLVVTIGKTVTNRAKLNWWESRALYGW
TVLVPRTKDQAGEMSERLTAYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFT
STNAVRAVWEKFGEFGLDARAFSGVKIACVGESTADRVRAFGISPELVPSGEQSSIGLLD
EFPPYDSVFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMI
KTGGFDAVCFTSSSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVG
PLVDALAEHAARLRAEGALPPPRKKSRRR
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
atgactcgccaaccgaccatgcgagtgcgcaagccgaggccgggccgcatcacgttcgtg
ggttccggtccgggcgacccgggactgctgaccacgcgggcggcgaccgtgttggcgaac
gcggccctggtgttcatcgacccgtgcgtgcccgagccggtgttggcgctgatcggcaag
gatttgccgccggtgtccggcccggcgccggccgctccgggctccgggaacgccgatggg
gccatcgaaggcgacgaccgcggccagcaccccccggccgtggtgtccggcggccccgat
atccggccggcactgggggatcccgtcgaggtcgccaagatgctgaccaccgaagcccgc
gcgggggccgacgtggtgcggctggtgtccggtgatccgctgaccgtggacgccgttatc
gccgaggtcaacgccgtcgcacgcacccacctgcacatcgagatcgtgcccggcctggcc
cccagcaacgcggtcccgacgtatgcggggctgccgctgggctcgtcgcacacggtcgcc
gacgtgcgtatcgaccccgaaaacaccgattgggaggcgctggccgccgcacccgggccg
ctgatcctgcaggccagcgcggcgcaactggccgatgccgcccgcaccctgatcgaccac
cagctcgccgagaccaccccgtgcgtggtgaccgcgcacggcaccacctgccagcaacgc
tcgctcgagaccacgttgcagggcttgaccgacccggcggtgctgggcggcgccgacgcc
aggctgtcccccgcgaacgggggagagccgttcaccggaccgctggtggtgaccatcggc
aagacggtgaccaaccgggccaagctgaactggtgggagagccgggcgctctacggctgg
accgtgttggtgccgcgcaccaaggatcaagccggcgagatgagtgagcggttgacggca
tacggagcgctgccggtggaggtgccgaccatcgccgtggaaccgccgcgcagccccgcg
cagatggaacgcgcggtcaagggcctggttgatggccgattccagtgggtggtgttcacc
tccaccaacgcggtgcgcgcggtgtgggagaagttcggtgagttcggtctggatgctcgc
gcgttctccggtgtgaagatcgcctgtgtcggcgagtcgacggccgaccgggtccgcgcc
ttcggaatcagccccgagctggtgccgtccggggagcagtcgtcgatcggcctgctggac
gaattcccgccttacgacagcgttttcgaccccgtgaaccgggttttgctgccgcgcgcc
gacatcgccaccgagacgttggccgagggcctgcgcgagcgtggttgggagatcgaggac
gttaccgcctatcggacggtgcgggccgccccgccgccggcggccactcgggaaatgatc
aaaacgggtggcttcgacgcggtgtgcttcacctccagctcgacggtgcgaaacctggtc
ggcattgccggcaagccgcacgcgcggaccatcatcgcctgcatcggccccaagaccgcc
gagaccgccgccgagtttgggcttcgggtggacgtccagccggagacggccgcggtgggc
ccgctggtggacgcgctggccgagcacgccgcccggctgcgtgccgagggcgcgctgccc
ccgccccgcaagaagagccgcaggcgctag
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