Mycobacterium tuberculosis F11: TBFG_13010
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Entry
TBFG_13010 CDS
T00545
Name
(GenBank) 3-isopropylmalate dehydrogenase leuB
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
mtf
Mycobacterium tuberculosis F11
Pathway
mtf00290
Valine, leucine and isoleucine biosynthesis
mtf00660
C5-Branched dibasic acid metabolism
mtf01100
Metabolic pathways
mtf01110
Biosynthesis of secondary metabolites
mtf01210
2-Oxocarboxylic acid metabolism
mtf01230
Biosynthesis of amino acids
Module
mtf_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mtf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
TBFG_13010
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TBFG_13010
Enzymes [BR:
mtf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
TBFG_13010
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Motif
Pfam:
Iso_dh
IFRD
Motif
Other DBs
NCBI-ProteinID:
ABR07337
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Position
complement(3364167..3365177)
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AA seq
336 aa
AA seq
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MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN
VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
NT seq
1011 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcgcgatcattgccggtgacgggatcgggcccgaggtaaccgccgaggcggtc
aaagtgctcgacgcggttgtgccgggcgtccagaaaaccagctatgacctgggtgcgcgg
cgctttcatgccaccggcgaggtgctgccggactcggtggtggccgagctgcgcaaccac
gacgcgatcctgctcggggcgatcggtgacccgtcggtgccaagcggcgtcttggagcgc
ggtctgttgctgcgactgcgcttcgagctggatcaccacatcaacctgcgtccggcccgg
ctgtatccgggggtggccagcccgctgtccggcaatcccggcatcgacttcgtggtggtg
cgcgagggcaccgagggaccctacaccggcaacggcggggcgattcgcgtcggcacgccc
aacgaggtggccaccgaagtcagcgtgaacaccgcgttcggtgtgcggcgtgtggttgcc
gacgcgttcgagcgggctcgacggcgtcgcaagcatctgacattggtgcacaaaacgaac
gtgttgaccttcgccgggggattgtggttgcggaccgtcgacgaggtcggcgaatgctac
ccggacgtcgaggtggcctaccagcacgtcgacgccgccaccatccacatgatcaccgac
ccgggtcgcttcgacgtgatcgtcaccgacaacctgttcggcgacatcatcaccgatctg
gccgcggcggtatgtggcggtatcggcttggcggccagtgggaatatcgacgcgacccgg
gccaacccgtcgatgttcgagccggtgcatggcagcgcgccggacatcgccggtcagggc
atcgccgacccgacggcggcgatcatgtcggtggcgttattgctgtcccaccttggcgaa
cacgacgcggctgcccgggtggaccgggccgtcgaggcccatttggccacgcgtggcagc
gaacggcttgccaccagcgatgtcggcgaacggattgccgccgcgctctag
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