Mycolicibacterium thermoresistibile: 4412656_01880
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Entry
4412656_01880 CDS
T05542
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mthn
Mycolicibacterium thermoresistibile
Pathway
mthn00300
Lysine biosynthesis
mthn00550
Peptidoglycan biosynthesis
mthn01100
Metabolic pathways
mthn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mthn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
4412656_01880 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
4412656_01880 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
4412656_01880 (murF)
Enzymes [BR:
mthn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
4412656_01880 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
SNW18064
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Position
1:2001907..2003424
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AA seq
505 aa
AA seq
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MIELSIAEIADITGGRLSDITAEQAAATKVTGTVEFDSRKVTPGGLFLALPGARSDGHDH
AADAVAAGAVAVLAARPVGVPAIVVDPEPTDTSSGAGVLEHDTDGSGAAVLAALGRLARA
VADELVAGGLRIVGVTGSSGKTSTKDLLAAVLAPLGSVVAPPGSFNNELGHPWTVLRADR
DTDYLVLEMSARHRGNIAALAEIAPPSVGVVLNVGTAHLGEFGSRDAIAATKAELAEAVP
STGLVVLNADDPAVAAMAERTAARVVRVAQDPGERQVDVWAERVSLDELARPRFTLRTPD
GAVEVALTVHGEHQVSNALAAAAVALHCGATLEQVVAALAGAGPASPRRMQVSTRSDGVT
VINDAYNANPDSMRAALKSLVWMAKAGGRAGGPPRRSWAVLGEMAELGDDAITEHDNIGR
LAVRLDVSRLIVVGTGRAMSAMHHGAVMEGSWGAESTMVSDADAALRLLRSELQAGDVVL
VKASNAAGLGALADALAAESGDTGR
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagctgagcatcgccgagatcgccgacatcaccggcggccggctgtccgacatc
accgccgaacaggcggccgcgaccaaggtgaccggcaccgtcgaattcgactcccggaag
gtgacgccgggcgggctgttcctggcgttgcccggcgcccgctccgacggccacgaccac
gccgccgacgcggtggccgccggagccgtcgcggtgctggcggcccggccggtcggggtg
ccggccatcgtcgtcgaccccgagcccaccgacacctcgagcggggccggtgtgctcgaa
cacgacaccgacggttcgggcgcggcggtgctggcggcgctgggccggctggcccgcgcg
gtggccgacgaactcgtcgccggggggctgaggatcgtcggggtcaccggatcgtcgggc
aagacctccaccaaggatctgctggccgcggtgctggccccgctggggtcggtggtggct
ccgcccggctcgttcaacaacgaactgggccacccgtggacggtgctgcgggccgaccgc
gacaccgactacctggtgctggagatgtcggctcgccaccgcggcaacatcgcggcgctg
gccgagatcgcgccgccgtcggtgggtgtggtgctcaacgtcggcaccgcccacctcggt
gagttcggctcccgcgacgccatcgccgccaccaaggccgaactggccgaagccgttcca
tccaccggcctggtggtgctcaacgccgacgacccggcggtggccgcgatggccgagcgg
accgcggcccgggtggtgagggtggcgcaggacccgggggagcgtcaggtggacgtgtgg
gccgagcgggtgtcgctggacgaactggcccggccccggttcaccctgcgcacccccgac
ggcgcggtggaggtcgcgctgacggtgcacggtgagcatcaggtgtccaacgccctggcc
gcggccgcggtggccctgcactgtggggccaccctggagcaggtggtcgccgcgctggcg
ggcgcgggcccggcctcgccacgccggatgcaggtcagcacccgcagcgacggggtcacc
gtgatcaacgacgcctacaacgccaaccccgactcgatgcgggcggcgctgaaatcgctg
gtctggatggccaaggcgggcggacgcgcgggcgggccgccgcgccgcagctgggcggtg
ctgggggagatggccgagctcggcgacgacgcgataaccgaacacgacaacatcggccgg
ttggcggtgcgcttagatgtctctcgactcatcgtggttggaaccgggagggctatgagc
gcgatgcaccacggcgcggtcatggagggatcgtggggcgccgagtcgaccatggtctcc
gatgccgacgccgcactgcggctgctgcgatccgaactgcaggccggtgacgtcgtgctg
gtcaaggcctccaacgcggcggggctgggcgcgctggccgacgccctggccgcggaatcg
ggggacaccggtcgatga
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