Mycobacterium tuberculosis KZN 4207: TBSG_00066
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Entry
TBSG_00066 CDS
T01690
Name
(GenBank) isocitrate dehydrogenase [NADP] icd2
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
mtk
Mycobacterium tuberculosis KZN 4207
Pathway
mtk00020
Citrate cycle (TCA cycle)
mtk00480
Glutathione metabolism
mtk01100
Metabolic pathways
mtk01110
Biosynthesis of secondary metabolites
mtk01120
Microbial metabolism in diverse environments
mtk01200
Carbon metabolism
mtk01210
2-Oxocarboxylic acid metabolism
mtk01230
Biosynthesis of amino acids
Module
mtk_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mtk_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
mtk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
TBSG_00066
09106 Metabolism of other amino acids
00480 Glutathione metabolism
TBSG_00066
Enzymes [BR:
mtk01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
TBSG_00066
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Gene cluster
GFIT
Motif
Pfam:
IDH
Motif
Other DBs
NCBI-ProteinID:
AEB02195
LinkDB
All DBs
Position
complement(72413..74650)
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AA seq
745 aa
AA seq
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MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE
EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ
EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH
GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE
QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS
DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR
AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE
EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA
RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD
TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN
HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR
GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA
PDSDMTTAVMRPSKTFNAALEAVQG
NT seq
2238 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgaacagccgaccatcatttacacgctgaccgacgaggcgccgctgctggcg
acctacgcctttctgccgattgtgcgtgcctttgccgaaccggcgggcatcaagatcgag
gccagcgacatctctgtagcggcacgcatcctggcggaattccccgattacctgaccgag
gagcagcgggtaccggataacctcgccgaactgggccggctgactcagctacccgacacc
aacatcatcaagctgccgaacatcagcgcctcggtgccacagctggtagccgccatcaag
gaactgcaagacaagggttacgcggtcccagactacccggcggacccgaagactgaccag
gagaaggccatcaaagagcgctacgccagatgcctgggcagcgcggtgaacccggtactg
cgccaaggcaattcggaccgtcgggcgcccaaagcggtgaaggagtacgcgcgcaagcac
ccgcacagcatgggcgagtggtcgatggcctcacgcacccacgtagcgcacatgcggcac
ggtgacttctacgccggcgagaagtcgatgacactggaccgcgcgcgcaacgtgaggatg
gaactgctggccaagagcggcaagacgatcgtgctcaagcccgaggtgccgctggatgac
ggcgacgtcatcgacagcatgttcatgagcaagaaagcgctgtgcgacttctacgaagag
cagatgcaggatgcgttcgagaccggcgtgatgttctccttgcacgtcaaggcgaccatg
atgaaggtcagccaccccatcgtcttcggccacgcggtcaggatcttctacaaggacgcc
ttcgccaagcaccaggagctgttcgacgacttgggcgtcaacgtcaacaatggcttgtcc
gatctgtacagcaagatcgagtcgctgccggcgtcgcaacgcgacgagatcatcgaggac
ctacaccgttgccacgaacaccgccccgagctcgcgatggtcgattcggccagaggtatc
tccaacttccactcgccgagcgatgtgatcgtggacgcctcgatgcccgcgatgattcgc
gcgggcggcaagatgtatggcgccgacggaaagctcaaggacaccaaggcggtcaacccg
gagtccaccttctcgcgcatctatcaggagatcatcaacttctgcaagacaaatggccag
ttcgatccgacgacgatgggcaccgtccccaatgtgggtctgatggcccagcaggccgag
gagtacggctcgcacgacaagacgttcgagattcccgaggacggcgtcgccaacatcgtc
gatgtcgccaccggcgaggtgctgctgaccgagaacgtggaagccggcgacatctggcgc
atgtgcatcgtcaaggacgcaccgatccgtgactgggtcaagctggctgtcacccgcgcg
cgcatctccgggatgccggtgctgttctggctggacccgtaccgcccgcacgagaacgag
ctgatcaagaaggtcaagacatacctgaaagatcacgacaccgaaggtctggacatccag
atcatgtcgcaagtgcgatccatgcgctacacgtgcgagcgcctggtccgtggactggac
accatcgccgcgaccggcaacatcctgcgcgactacctcaccgacctgttcccgatcctg
gagttaggcaccagcgccaagatgctgtccgtcgttccgctgatggccggcggcggaatg
tacgagacgggggcgggcggttcggcacccaagcacgtcaaacaattggtggaggagaat
cacctgcgctgggattctctgggtgagttcctcgcgctgggcgccggtttcgaggatatc
ggcatcaagaccggtaacgagcgggccaaactcttgggtaagaccctggatgccgccatc
ggcaagctgctggacaacgacaagagtccgtcgcgcaaaaccggtgaactcgacaaccgg
ggcagccagttctacctcgccatgtactgggcacaagagctggccgcgcagaccgacgac
cagcagctggccgaacacttcgcctcgctggcagatgtgttgaccaaaaacgaagacgtc
atcgtgcgagagctcaccgaggtacaaggcgaaccggtggacatcggcggctactacgcg
ccggacagcgacatgactacggcggtgatgcggcccagcaagacgttcaatgcagcgctg
gaggctgtccaaggctga
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