KEGG   Mycobacterium tuberculosis H37Rv: RVBD_0570
Entry
RVBD_0570         CDS       T02178                                 
Name
(GenBank) ribonucleoside-diphosphate reductase NrdZ
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
mtv  Mycobacterium tuberculosis H37Rv
Pathway
mtv00230  Purine metabolism
mtv00240  Pyrimidine metabolism
mtv01100  Metabolic pathways
mtv01232  Nucleotide metabolism
Module
mtv_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
mtv_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mtv00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    RVBD_0570
   00240 Pyrimidine metabolism
    RVBD_0570
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mtv03400]
    RVBD_0570
Enzymes [BR:mtv01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     RVBD_0570
DNA repair and recombination proteins [BR:mtv03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    RVBD_0570
SSDB
Motif
Pfam: Ribonuc_red_lgC Ribonuc_red_lgN ATP-cone RNR-II_ins_dom
Other DBs
NCBI-ProteinID: AFN48432
LinkDB
Position
661298..663376
AA seq 692 aa
MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMPGTVAKAVADALGRGIAP
VEDIQDCVEARLGEAGLDDVARVYIIYRQRRAELRTAKALLGVRDELKLSLAAVTVLRER
YLLHDEQGRPAESTGELMDRSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTL
MNSGTDLGLLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVASTG
GTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAKAESPSELPHFNL
SVGVTDAFLRAVERNGLHRLVNPRTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTIN
RANPVPGRGRIEATNPCGEVPLLPYESCNLGSINLARMLADGRVDWDRLEEVAGVAVRFL
DDVIDVSRYPFPELGEAARATRKIGLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQ
AAHTASRRLAEERGAFPAFTDSRFARSGPRRNAQVTSVAPTGTISLIAGTTAGIEPMFAI
AFTRAIVGRHLLEVNPCFDRLARDRGFYRDELIAEIAQRGGVRGYPRLPAEVRAAFPTAA
EIAPQWHLRMQAAVQRHVEAAVSKTVNLPATATVDDVRAIYVAAWKAKVKGITVYRYGSR
EGQVLSYAAPKPLLAQADTEFSGGCAGRSCEF
NT seq 2079 nt   +upstreamnt  +downstreamnt
gtgggtgtcagctggccggcgaaagtccggcgccgggatggaacgctggtgccgttcgac
atcgcgcggatcgaagcagcggtgacgcgggcagcgcgcgaggtggcttgcgacgacccc
gatatgccgggcaccgtagcgaaagccgtcgccgacgcactcgggcgcggtatcgctccc
gttgaggacattcaggactgcgtggaggcccggctgggggaagccggtctggatgacgtg
gcccgtgtttacatcatctaccggcagcggcgcgccgagctgcggacggctaaggccttg
ctcggcgtgcgggacgagttaaagctgagcttggcggccgtgacggtactgcgcgagcgc
tatctgctgcacgacgagcagggccggccggccgagtcgaccggcgagctgatggaccga
tcggcgcgctgtgtcgcggcggccgaggaccagtatgagccgggctcgtcgaggcggtgg
gccgagcggttcgccacgctattacgcaacctggaattcctgccgaattcgcccacgttg
atgaactctggcaccgacctgggactgctcgccggctgttttgttctgccgattgaggat
tcgctgcaatcgatctttgcgacgctgggacaggccgccgagctgcagcgggctggaggc
ggcaccggatatgcgttcagccacctgcgacccgccggggatcgggtggcctccacgggc
ggcacggccagcggaccggtgtcgtttctacggctgtatgacagtgccgcgggtgtggtc
tccatgggcggtcgccggcgtggcgcctgtatggctgtgcttgatgtgtcgcacccggat
atctgtgatttcgtcaccgccaaggccgaatcccccagcgagctcccgcatttcaaccta
tcggttggtgtgaccgacgcgttcctgcgggccgtcgaacgcaacggcctacaccggctg
gtcaatccgcgaaccggcaagatcgtcgcgcggatgcccgccgccgagctgttcgacgcc
atctgcaaagccgcgcacgccggtggcgatcccgggctggtgtttctcgacacgatcaat
agggcaaacccggtgccggggagaggccgcatcgaggcgaccaacccgtgcggggaggtc
ccactgctgccttacgagtcatgtaatctcggctcgatcaacctcgcccggatgctcgcc
gacggtcgcgtcgactgggaccggctcgaggaggtcgccggtgtggcggtgcggttcctt
gatgacgtcatcgatgtcagccgctaccccttccccgaactgggtgaggcggcccgcgcc
acccgcaagatcgggctgggagtcatgggtttggcggaactgcttgccgcactgggtatt
ccgtacgacagtgaagaagccgtgcggttagccacccggctcatgcgtcgcatacagcag
gcggcgcacacggcatcgcggaggctggccgaagagcggggcgcattcccggcgttcacc
gatagccggttcgcgcggtcgggcccgaggcgcaacgcacaggtcacctccgtcgctccg
acgggcaccatctcactgatcgccggaaccaccgcgggcatcgagccgatgttcgctatc
gcgttcacccgcgccatcgtcggccggcatctgctggaggtcaatccgtgcttcgaccga
ctggcccgcgatcggggcttttatcgtgacgagctgatcgccgagatcgctcagcgtggc
ggagtccgtggctatccgcggctgcctgctgaggtgcgggccgcgttcccgaccgcggcg
gagatcgcgccgcagtggcatctgcgcatgcaggccgcggtgcagcgccacgtcgaggcc
gccgtgtccaagacggtcaacttgcccgccacggcgacggtcgatgacgtccgcgccatc
tatgtggccgcctggaaggcaaaggtcaagggcatcacggtgtatcgctacggcagccgg
gaaggacaggtactgtcctacgccgcgccgaaaccgctactggcgcaggctgacacggag
ttcagcggcggctgtgcgggccgctcctgcgagttctga

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