KEGG   Maylandia zebra (zebra mbuna): 101487235
Entry
101487235         CDS       T02814                                 
Symbol
wnk2
Name
(RefSeq) serine/threonine-protein kinase WNK2 isoform X1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
mze  Maylandia zebra (zebra mbuna)
Brite
KEGG Orthology (KO) [BR:mze00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mze01001]
    101487235 (wnk2)
   01009 Protein phosphatases and associated proteins [BR:mze01009]
    101487235 (wnk2)
Enzymes [BR:mze01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101487235 (wnk2)
Protein kinases [BR:mze01001]
 Serine/threonine kinases: Other
  Wnk family
   101487235 (wnk2)
Protein phosphatases and associated proteins [BR:mze01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101487235 (wnk2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C
Other DBs
NCBI-GeneID: 101487235
NCBI-ProteinID: XP_004546198
LinkDB
Position
LG20:complement(17740027..17780708)
AA seq 2782 aa
MEPESKSGSGDHQDLRNSPVTKSQCEPGKNVREAMGDGPVSLVDSVVRGGSDPSAYPSSS
YQRIVHQRFIRRSLWFSDTDEQAFEAPECNNRSKILNINLRTIVDRSRGTSCGIQEGSST
ESQGGLKDSATESASADEDKEKGGDALNVTCSDGGKAAVKAASEENEEEAEMKAVSTSPG
GRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLSKMERQRFKEEAEMLKGLQH
PNIVRFYDFWESPLKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLHF
LHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKAASFAKSVIGTPEFMAPEMYEE
HYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGVKPASYNKVMDPEIKEIIG
ECICQKKEERYTIKDLLNHAFFAEDTGVRVELAEEDDGKKSSIALKLWVEDPKKLKGKYK
ESGAIEFTFDLEKEVPEVVAQEMVESGFFHESDAKTVGKSIRDRVALIKWRRERTVSAAA
AENQGEGGHGTQMTPSQGISAGVPHVGQPLVLEPEEPEADQYNRLHNLTASATSVTSDST
LDSGMGSTVYSDSHSSQHSVLYQSLLEPITMATQQCPSSSHFLTDRPQYCEQGEVWEATL
SPELRARLGAEGRRGSAPVIDIQRANHIARLHALIQSKRSVSPNPTVPERSELSSAELHS
ESYGGFSPQSAMPVIKVSPVSSPTDHRRLSDINIRSPSETLSLPVPTERRHSDLSSLLSL
TSHHNHHIAMHRGSACQACISMLHLRSQDWRHHCHSVVMPTHQCPCDFRHHPSPGGMMST
PGYGLLKASSDYSNFSQLQQSLFNIISRKAAPCPPTPAQASSLYSSAALSPTGSDGDCSL
KSQFQISSLVGDHEPLQECEDRCCAREQQVTRAVGVASSAGYQTQQSVQGLSSSSSTVHA
PPQYLQPGHSYPATLYAPQPCAPTPAPASLCSVNIQHATSAGSYSPPNVQQAQVAASIVP
SAVPQHVVQSYQAPVQQQQQVTAANSLTFPLQVQQTSQNSVAPPLQQAQSASGSVQQPTA
ATTLPAQQPTENCPSASAAPSMAPTVQGQPVQASSTLQQAQTTVKLPNQQHSQNSATPAL
YSQQISIQQEHQQSLSQNAQQNAGKACVQSQLQHGQETVYAMHQQMAQHPTQQSQSLHCS
TQQQVHTPNVQQHSQKTIQTAVPQQSQDVSQSQPQTTATQVLQVPAKHQSYSAAGPHDAA
SQSYAHSALQQTAPGQSQYLPAQSVCPQTYIAANQVLTSQSISTSSQQGQAEHTTQQNIS
AGQSISQLGQGGQGHGQNVSQPASSGPAQALSAQQSTAHQQQLQPLQISASLSPSHQPQF
PSQYPTVQVMAAVTDSESSFPHSCTAPPPSASTSLNHIFLSPGHTVPATPSVSPISPLHI
ENTLVSPISVSLIPSPSHALSKIEPTSPQPQHTARSEVSHASPAFISALTTHPTHTHTAR
CQNTHPSTIGSSQPLIQAPQQSQVSHPEPVPCAQSVQPSQLKQAAVFSSHVQNGAELGTA
SAAAQLDSVSPCQLPPQAQPQSQVQSQIPVLQSADSQRASSGSASSCWTQQKQLSNVTGA
AGQGPSEINMEDQAAEKHTGGQSYDSVNSDATSGKEMSDGYEGTHGGRCDGKVRKHHRRS
SRTRSRQEKLSRPKLSMLNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPEEIATYMVE
NDFILPLEKEVFIEQLKDIVDKAEDMLSEDTEGERNSDQGGSPKQSEGPGTLGTEASSPS
TPQLVYQQNVLHTGKRWFIICPVAETPMHDKENTSHAQESEKSGSSSVGANGNTAAVPTQ
VVSLSSQNPSSSSSLTTAAQTSVQPPDQITSKAHIQQTQPGVTKHALGSSAANHRSSLSV
EEPCISAVSMVTDMPCCAIVPPVSLDVNGIEKGTPGGLVSSQTNQPIQKASPTGEAPPQL
TSLQSVVMQQPYATPMQPGTVTSQPQSPAHQNSQSSSHQQCVGPGESDSEGPRRVEFVDR
TIKTLDEKLRNLLYQEHAPSQPSSLTSETQASSTEGVSSPPVSDGQSTEGALTKKKGEPL
PQIPERTDDVGTLSDSAVPGTNRGLKRSDVPASSGAHGYKSRFQIIPTPPDVICRLEKSK
TSCSSCSSPAPSSGSGGSYSQAQSMNKKERGCVAMSRSSVKPRDEDENAETSKSHRSSRY
SAPPNFYQATPSSSPDSTPCHIPRAQTIDASAHHHYRFPSHLCSDSADEDSSSVALPPAH
PAPPAHTLSEHSGSDLMKRAVAFLRRSGRSKSEQSSDSPSRQPVSMNGHTPSPSAGHAPS
SYVSSDNDSEFEDADMRKELQKLREKHMKEISELQAFQRSEIERLYKELGKTLPPNVSLL
HAAPPSGRRRKASKHKLKAGKLLNPMVQQLKNNLNTTSADRKGESAASSSGSPAKSSVLS
DGSAHSSGCSSSSNQPSTAPEHVHTQQPCSLKGSFSSDNIYAGLHGDGNPNHAGPGQGWT
VYHQTSERVTYKSSSKPRTRFLSGPVSLSIWSTLKRLCLGKERSSRSSLNTTTAQTASSQ
TQPSLSAATSSPSPQPFTRLAQVQTNNSNNKRGTFTDDLHKLVDDWTKETVAAASQARPS
LNQMKQQRRRQDLEGGAAPMGAVTREMKCHNGPGKFQLPLSCPPTAALGPRIPATLSSNS
STAPSPGYLIPAGSYAGMVPGPLYPQRWPSLPSPVGSVVPLGLLGAARMMPYGTMANPQI
QAYPLVIHSPENGPCPKTTRTT
NT seq 8349 nt   +upstreamnt  +downstreamnt
atggagccggagtctaaatcaggctccggggaccatcaagacctgagaaattcgcctgta
accaagtctcagtgtgaaccgggcaaaaatgtgcgcgaggccatgggtgatggacccgtc
agtcttgtggactctgtagtgagaggtgggagtgaccccagcgcatatccttcctccagt
tatcagaggattgtgcatcagagattcatcaggagaagtttatggttttcagacacagat
gagcaggcctttgaagcacctgaatgtaataacaggagtaagatcctaaacattaacctg
cgaacaattgtggacaggtcaagggggaccagctgtgggatacaggagggatccagcact
gaaagtcaaggtgggcttaaagacagtgcaacagagagcgccagcgccgatgaggacaag
gagaaaggtggagacgcgctaaatgttacatgcagtgatggtggtaaagctgctgtcaag
gcagccagtgaggagaatgaggaggaggcagagatgaaggcagtctccacgtctccaggg
ggaaggttccttaaatttgacatagagctggggagaggttccttcaagacagtctacaaa
ggcctggatactgagacctgggtggaggtggcctggtgtgagctgcaggatcgtaagctt
tctaaaatggaacgtcagcgctttaaagaggaagcagaaatgttgaaaggcctccagcat
cccaacattgtccgtttctacgacttctgggagtcaccgcttaaaggaaagaagtgcatt
gttttagtaacagagctcatgacgtcaggaacgctaaaaacctatctaaagcgtttcaag
gtaatgaagcccaaagtgttaaggagctggtgtagacagatccttaaaggcctccacttt
ctccacaccaggacgcctcccatcatccacagagatcttaaatgtgacaacatctttatt
actggacctacaggttcagtaaagataggggatttaggtctggcaacactcaaggcagct
tcttttgctaagagtgtcataggcactccagagttcatggccccagagatgtatgaggaa
cactatgacgaggctgtggatgtctatgcctttggcatgtgtatgctagaaatggccacc
tctgaatatccctattctgagtgtcagaatgctgctcaaatctaccgcaaagttaccagt
ggagtaaagccagccagctacaacaaggtcatggatcctgaaatcaaggagatcattgga
gagtgcatctgccaaaagaaagaggaacggtacacgatcaaagatctgttgaatcacgct
ttttttgccgaggacacaggtgtgagggtggagctagctgaggaggatgatggaaaaaag
tcctcaatagctctcaaactgtgggtggaggaccccaagaagttaaaagggaaatacaag
gagagtggggccattgagtttacatttgacctggagaaggaggtccctgaggttgtcgca
caagaaatggtggagtctggcttcttccatgagagtgatgctaagaccgtgggaaagtcg
atcagggaccgtgtggcactgatcaaatggagacgagagcgcacagtgtctgcagcggct
gcagagaatcagggtgaaggaggacacggcacccagatgacaccatctcagggcatctct
gctggggtgccacatgtagggcagccccttgtgctggaaccagaagagccagaggcagac
cagtacaacaggctgcataacctcacagccagtgccacctcagtaacatcagacagcaca
cttgacagtggcatgggctccacagtgtactcggactcccacagcagccagcacagtgtc
ctctaccagtccctgctcgagcctattactatggcaacacagcagtgcccgagcagtagc
cattttctgacagatcgaccccagtactgcgaacagggtgaagtgtgggaggcaacgctg
agcccagagctcagggctcgattgggagctgaaggccggaggggaagtgcccctgttatt
gacattcaaagggcaaaccacattgctcgactgcatgccctcattcagtctaagagatca
gtcagtcccaacccaacggtaccagaacggtcagaactcagctctgctgagctgcactca
gagtcttatggagggttttccccacagagtgctatgccagtaatcaaagtctcccccgtc
tcttcacctactgaccaccgccgacttagtgatatcaacatcagatcgccatcagagaca
ttatcacttcctgtgccaactgaacgaaggcactctgaccttagtagtcttctgagtctg
acctctcatcacaaccaccatattgcgatgcacaggggctctgcgtgccaggcatgtatt
tctatgcttcatttgaggtcacaagattggaggcaccactgtcattctgttgtcatgcca
acgcaccaatgtccatgtgactttagacaccacccatcacctggtggaatgatgagcact
cctggctatggactgctgaaggcttcaagtgattattccaatttctcacagctgcagcag
tccctctttaatataatcagtcgcaaagcagccccttgtccccccacacctgcccaagcc
tcatcactgtactcttcagctgctctcagtccaaccgggagtgatggagactgcagccta
aagagtcagttccagattagcagtcttgttggggaccacgaacctctccaggagtgtgaa
gacagatgctgtgccagagagcagcaagttaccagggctgtaggagtggccagttctgca
ggttaccagactcaacaatctgtccaaggtctgtcctcttccagctccacagtgcatgca
ccaccacagtacctccagcctggacacagctaccctgctactttgtatgctcctcagcct
tgtgcaccaacaccagctccagccagtctatgttcagtcaacatccaacatgcgaccagt
gctggtagctactcaccgccaaatgtgcaacaggctcaagttgcagcaagtattgtacca
tcagctgtgccacaacatgttgtacaaagctaccaagcaccagtccagcaacagcagcaa
gtaactgcagcgaactctttgacttttcccttacaagtgcagcaaacatctcagaactct
gtggccccacctttacaacaggctcagtctgcatcaggatcagttcagcagccaactgca
gcaaccactctgccagcacagcagccaactgaaaattgtcctagtgcatctgcagcccca
tctatggcacccacagttcagggtcaaccagtacaagcttccagcacactgcagcaggcc
caaaccacagtcaaactgcccaatcagcaacatagtcaaaactctgccacaccagcactt
tacagtcagcaaatatccattcaacaagagcaccaacagtctttatcacaaaatgcacag
caaaatgctgggaaggcctgtgttcagtctcaactccagcatggccaagaaactgtgtat
gccatgcaccagcaaatggcacaacatccaacccaacaatcacaaagtcttcactgttcg
acacagcaacaagtgcacactccaaatgtccagcagcacagtcaaaaaactatccaaaca
gcagttccacaacagagtcaggatgtatcccagtctcagccccaaaccaccgcaactcaa
gttctgcaggttccagccaaacatcagagttactcagctgcaggtccacatgatgctgcc
tctcagagctatgcacattctgcacttcaacaaacagctccgggtcaaagtcagtacctg
cctgcccaatcagtctgtccacagacttacatagcagctaaccaggtactgacttctcag
agcatttcaacctcttctcagcaaggccaggctgaacataccacccaacagaatatctct
gctggtcagagcatttcacagcttggacagggtggacagggccatgggcagaatgtcagc
cagccagcttccagtgggccagcacaggcactctctgctcagcagtcaactgctcaccaa
cagcaactccagcctctgcagatttctgcttcactgtcaccatcacaccaaccacagttt
ccttcacagtatcccacagtccaggtgatggcagctgtgactgattctgaatcttccttc
cctcactcttgcactgctcctcccccttcagcctcaacctctcttaatcacatcttcctt
tctcctgggcatactgtccctgcgactccttctgtctctcccatttctcctctgcacatt
gaaaacacattagtttcacccatctcagtatccctcataccgtccccgtcacatgcactg
agtaagatagagcccacatccccacaaccacaacacactgctagatctgaggtttctcat
gcatcacctgcatttatatcagccctaaccacccaccccacacacacacacactgcccgg
tgccagaacacacacccttccacaattggcagcagtcagccactaatacaggctcctcag
cagtcccaggttagccatcccgagcctgttccctgtgctcagtcagtccagccatctcag
ctcaaacaagctgcagtcttttcttcacatgtgcagaatggggcagaactgggaacagcc
tctgcggctgcccagctggacagtgtgagcccatgccagctccccccacaggcccagccc
cagagtcaggttcaaagccaaattcctgtgctgcagtctgcagactcccagagagcatca
tctgggtctgccagttcctgttggactcagcagaagcaactgagtaatgtcacaggagct
gcaggtcagggtccatcagagattaacatggaggaccaagctgcagagaaacacacagga
ggacagagctatgacagtgtcaactccgatgccacgtcaggaaaggagatgagtgatggt
tatgaagggacacatggaggtagatgcgatgggaaagtccgcaaacaccaccgcaggtcc
tcacgcactcgttctcggcaagaaaagctcagcagaccaaagcttagcatgctgaatgtg
tgtaacactggggataaaatggtcgagtgtcagctggagactcataaccataaaatggtc
actttcaaatttgacctggatggagatgcaccagaagagattgctacatacatggtggag
aacgattttattctacctttagaaaaagaggtcttcattgagcagctgaaggacatcgta
gacaaggctgaggacatgctgagtgaggacactgagggtgagaggaactcagaccaggga
ggcagccccaaacagagtgaaggacctggcacactgggaacagaggcttcatctcccagc
accccacagctagtgtaccaacaaaatgtcctgcacactggtaagcgttggtttataatc
tgccccgtggctgagactcccatgcacgacaaagagaatacatcacacgcccaggaatct
gaaaagtctggctcatcgtcagtcggggccaacggcaacacagctgcagtgcctactcag
gtcgtctctttgtcctcccaaaacccgtcctcatcttcctcactgaccaccgcagctcaa
acctcggtccagcctccggaccaaatcactagcaaagcccacatccagcagacccagccc
ggtgttactaaacatgccctaggttctagtgccgccaaccatcgcagctcactttctgtg
gaagaaccttgcatctctgctgtttctatggttactgatatgccatgctgcgctattgtg
ccccctgtctcgctggatgtaaatggcattgagaaaggaacacctggtggtttggtttca
tctcagactaatcaaccaatccagaaggccagccctactggagaagctcctcctcagctg
acttcccttcagtctgtggtcatgcagcaaccttatgcaacgcccatgcagcctgggact
gtgacctcacagcctcaaagtcctgcacatcagaactcccagtcttcaagccatcagcag
tgtgtggggccaggcgagtcagacagtgaggggccacgcagggtggagtttgttgaccgc
actatcaagactttggatgagaagctgagaaacctgttataccaagagcatgctccttcc
cagccctcgagccttacatctgaaacccaggcatccagcacagagggggtcagctcccct
ccagtctcagatggccaaagcactgaaggagcacttacaaagaagaagggggaacctctg
cctcagattcctgagcgcacggatgatgtgggtacattaagtgactctgcagtgccaggt
actaacaggggtttaaaaagaagtgatgtgcctgccagctctggtgcacatggctacaaa
agccgttttcaaatcatcccaactccgccggatgttatttgtcgcttggaaaaaagcaag
acaagctgcagctcctgcagttccccagctccttctagtggttctggtgggtcttacagc
caggctcagagcatgaacaagaaagagagaggatgtgtggctatgagcaggtcatcagtg
aaacctcgagatgaagatgagaatgcagaaacatctaaatctcaccgcagtagccgttac
tctgctccgccaaacttctaccaggctacaccttcttctagtcctgacagcaccccatgc
cacattccccgggcccagactattgacgcttcagcacatcaccactatcgcttcccctct
cacctctgctctgactcagcagatgaggacagcagcagcgtagctcttcctcctgcacat
ccagctcctccggctcataccctgtctgagcacagtggaagtgacctcatgaagagggca
gtcgccttcctgcggcgctctgggcgaagcaaaagtgaacagagctctgattcaccgagc
cgacagcccgtgtcaatgaatggtcacactccttcgccttcagcaggacatgcaccctca
tcctacgtcagcagtgacaatgactctgagtttgaggatgcagatatgagaaaagaacta
cagaaacttagagaaaaacacatgaaggagatctcagagctgcaggcatttcagaggagt
gagattgaacgtctgtacaaggagttgggaaaaactctgccccccaatgtcagcctgctt
catgctgcacctccaagtggccgtaggcgcaaagccagcaaacacaagctaaaggctgga
aaactgctcaatccaatggtgcagcagctcaaaaacaatcttaatacaaccagtgctgac
agaaaaggtgagagtgctgccagctcgtccggctccccggctaaaagttcagttctatca
gatggctcagcccactccagcggctgctccagctccagcaatcagccgagcactgcccca
gagcatgtccacacccagcagccctgttctttgaagggttctttctcctcagacaacatc
tacgctggactacatggtgatggaaatcccaaccatgctggccctggtcaaggctggacg
gtttaccaccaaacgtcagagagagtcacctataaatctagtagcaaaccacgcactaga
ttcctcagtggacctgtgtctctgtccatctggtccactctgaaacgactatgtctaggc
aaagaacgcagtagtaggtcctctctcaacaccaccactgctcagacagcctccagtcag
actcagccatcactctctgcagcaacatcctcgccctctcctcagccattcacacgtctc
gctcaggtccagaccaacaacagcaacaacaagagaggcacgtttactgatgatcttcac
aaactggttgatgactggacaaaggaaactgtagcagcggccagtcaagcacgaccttcc
ctgaaccagatgaaacagcagaggcgtcggcaagacctggaaggcggtgcagcaccgatg
ggagcagttactcgtgagatgaaatgtcataatggtcccggcaagttccagctgcctctt
tcatgccccccgactgctgctttaggccctcgtatacctgcaaccctatcgtcaaactca
tccacagcgccctctcctggttacctcattcccgcaggctcctatgctgggatggttccc
ggtcctctttatccccagagatggcccagcttgcccagtcctgtagggtctgtggtcccc
ttaggcttgcttggtgcagcaagaatgatgccctatggcacaatggcaaacccacagatt
caagcttaccctctggtcatccacagtcccgagaatggcccgtgtccaaaaaccacaagg
actacttga

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