Neisseria cinerea: NCTC10294_00333
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Entry
NCTC10294_00333 CDS
T06828
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ncz
Neisseria cinerea
Pathway
ncz00790
Folate biosynthesis
ncz01100
Metabolic pathways
ncz01240
Biosynthesis of cofactors
Module
ncz_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ncz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NCTC10294_00333 (folC)
Enzymes [BR:
ncz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NCTC10294_00333 (folC)
6.3.2.17 tetrahydrofolate synthase
NCTC10294_00333 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
SQF82905
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Position
1:complement(327197..328471)
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AA seq
424 aa
AA seq
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MKTLQDWLSHLETAHSGGLIDMGLERTSEVKKRMKLEPQCPVVVVAGTNGKGSVCAYLTQ
IYKQAGFKVGTLTSPHLLRYNERIAVNAEPVSDDTITASFERIETARGEISLTYFEFNAL
AAVDIFIREQVDVMILEVGLGGRLDAVNVFDCDCAVVTSVDLDHQAFLGDTVEQVGFEKA
GVFRSGKPAICGQNPAPESLVAHAEAIGAKLLMVQRDFDFSSLENIQWNYRFHPQHSDDP
ARNRNSLPFPALRGAYQLSNAACALTVLECLNDKLPVDIGAIKRGLLLVENPGRFQVLPG
RPLTVLDVGHNPHAARALRRSLINLAFAQKRTAVFSMLSDKDIDGVLEIVKDQFDEWYIA
PLDVPRGMTLESLQNKLHEHSIENIQTFATVREAYRAAASKAGENDRIVVFGSFHTVADV
MSVL
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacattacaagactggctctcgcatttagaaaccgcacacagcggcggcttaatc
gacatgggattggaacgcacgagcgaagtgaaaaaacgcatgaagctcgagccgcaatgc
cccgtcgtcgttgtcgcgggaacaaacggtaaaggttcggtctgcgcctacctgacacag
atttacaaacaggcaggcttcaaagtcggtacgctgaccagcccgcatttattgcgttac
aacgaacgcatcgctgtcaacgccgaaccggtttcagacgacacaatcaccgcttccttc
gaacgcatcgaaaccgcgcgcggtgaaatatcactgacttattttgaattcaatgcgttg
gcggctgtcgatatcttcatacgcgaacaagtcgatgtaatgatattggaagtcggcttg
ggcggacgtttggacgcggtcaacgtgttcgactgcgattgcgcggtggttactagcgta
gatttggaccatcaggcgtttttgggcgatacggtcgagcaggtcggctttgaaaaagca
ggcgtgttccgcagcggcaaacccgcaatctgcggtcaaaaccccgcgcccgaatcattg
gtcgcacacgccgaagccataggcgcgaaactgctgatggtgcagcgcgatttcgatttc
tcctcattggaaaacatccaatggaactaccgcttccatccacaacattcagacgacccc
gctcgcaaccgcaattccctgccgttccccgcattgcgcggcgcataccaactttccaat
gccgcctgcgcgctgaccgtgttggaatgtttgaacgacaaattgccggtggacatcggc
gccatcaagcgcggtttgttactggttgaaaaccccggccgcttccaagtcctgcccggc
cgtccgctgaccgttttggatgtcggacacaatccccacgctgcccgcgccctgcgccgc
agcctgattaatttggcgtttgcgcaaaaacgcaccgccgtgttcagcatgttatccgac
aaagacatagacggcgtgttggaaatcgttaaagaccagtttgacgaatggtatatcgcg
cctttggacgtgccgcgcggcatgacgctcgagagcctgcaaaacaaactgcacgaacac
agcatcgaaaacatacagacatttgccaccgtccgcgaagcataccgggcggcagcctca
aaagcgggcgaaaacgacagaatcgtcgtattcggctcatttcataccgttgccgatgtc
atgtcggtactgtaa
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