Nomascus leucogenys (northern white-cheeked gibbon): 100593288
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Entry
100593288 CDS
T03265
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521
EGFR tyrosine kinase inhibitor resistance
nle01522
Endocrine resistance
nle04010
MAPK signaling pathway
nle04014
Ras signaling pathway
nle04015
Rap1 signaling pathway
nle04066
HIF-1 signaling pathway
nle04068
FoxO signaling pathway
nle04114
Oocyte meiosis
nle04140
Autophagy - animal
nle04144
Endocytosis
nle04150
mTOR signaling pathway
nle04151
PI3K-Akt signaling pathway
nle04152
AMPK signaling pathway
nle04211
Longevity regulating pathway
nle04213
Longevity regulating pathway - multiple species
nle04510
Focal adhesion
nle04520
Adherens junction
nle04550
Signaling pathways regulating pluripotency of stem cells
nle04730
Long-term depression
nle04913
Ovarian steroidogenesis
nle04914
Progesterone-mediated oocyte maturation
nle05200
Pathways in cancer
nle05202
Transcriptional misregulation in cancer
nle05205
Proteoglycans in cancer
nle05214
Glioma
nle05215
Prostate cancer
nle05218
Melanoma
nle05224
Breast cancer
nle05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100593288 (IGF1R)
04014 Ras signaling pathway
100593288 (IGF1R)
04015 Rap1 signaling pathway
100593288 (IGF1R)
04066 HIF-1 signaling pathway
100593288 (IGF1R)
04068 FoxO signaling pathway
100593288 (IGF1R)
04151 PI3K-Akt signaling pathway
100593288 (IGF1R)
04152 AMPK signaling pathway
100593288 (IGF1R)
04150 mTOR signaling pathway
100593288 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100593288 (IGF1R)
04140 Autophagy - animal
100593288 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
100593288 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100593288 (IGF1R)
04520 Adherens junction
100593288 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
100593288 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100593288 (IGF1R)
04914 Progesterone-mediated oocyte maturation
100593288 (IGF1R)
09156 Nervous system
04730 Long-term depression
100593288 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
100593288 (IGF1R)
04213 Longevity regulating pathway - multiple species
100593288 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100593288 (IGF1R)
05202 Transcriptional misregulation in cancer
100593288 (IGF1R)
05205 Proteoglycans in cancer
100593288 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100593288 (IGF1R)
05214 Glioma
100593288 (IGF1R)
05218 Melanoma
100593288 (IGF1R)
05215 Prostate cancer
100593288 (IGF1R)
05224 Breast cancer
100593288 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100593288 (IGF1R)
01522 Endocrine resistance
100593288 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nle01001
]
100593288 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
nle04090
]
100593288 (IGF1R)
Enzymes [BR:
nle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100593288 (IGF1R)
Protein kinases [BR:
nle01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100593288 (IGF1R)
CD molecules [BR:
nle04090
]
Proteins
100593288 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
DUF4476
Motif
Other DBs
NCBI-GeneID:
100593288
NCBI-ProteinID:
XP_030670930
LinkDB
All DBs
Position
6:117288671..117607780
Genome browser
AA seq
1367 aa
AA seq
DB search
MKAGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDIMQVANSTTSSRSRNTTATDAYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaaggctggctccggaggagggtccccgacctcgctgtgggggctcctgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggctgaggactaccgcagctaccgcttccccaagctcacggtc
attaccgagtacttgctgctgttccgagtggctggcctcgagagccttggagacctcttc
cccaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttc
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccactgtggactggtccctgatc
ctggatgcggtgtccaataactacattgtggggaataagcccccaaaggaatgtggggac
ctgtgtccagggaccatggaggagaagccgatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagcgcgtgtggg
aagcgggcatgcaccgagaacaacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgcgtagcttgccgccactactactacgccggtgtctgc
gtgcctgcctgcccgcccaacacctacaggtttgagggctggcgctgcgtggaccgtgac
ttctgcgccaacatcctcagcgccgagagcagcgactctgagggatttgtgatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttg
ctcatcaacatccgccgggggaataacattgcttcagaactggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccattctcacgccttggtctccttgtcc
ttcctaaaaaaccttcgcctcatcttaggagaggagcagctagaagggaattactccttc
tatgtcctcgacaaccagaacttgcagcaactgtgggactgggaccaccgcaacctgacc
atcaaagcagggaaaatgtactttgctttcaatcccaaattatgtgtttccgaaatttac
cgcatggaggaagtgacggggactaaagggcgccaaagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgacgtcctgcatttcacctccaccaccacg
tggaagaatcgcatcatcataacctggcaccggtaccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccctttaagaatgtcacggagtatgatggg
caggacgcctgcggctccaacagctggaacatggtggacgtggaccttccgcccaacaag
gacgtggagcccggcatcttactgcatgggctgaagccctggactcagtacgccgtttat
gtcaaggctgtgaccctcaccatggtggagaacgaccacatccgtggggccaagagtgag
atcttgtacattcgcaccaatgcttcagttccttccattcccttggacgttctttcagca
tcgaactcctcttctcagttaattgtgaagtggaaccctccttctctgcccaacggcaac
ctgagttactacattgtgcgctggcagcggcagcctcaggacggctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccatcgacatt
gaggaggtcacagagaaccccaagactgaggtgtgtggtggagagaaaggaccttgctgc
gcctgtcccaaaaccgaagccgagaagcaggccgagaaggaggaggctgagtaccgcaaa
gtctttgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcggaga
gacatcatgcaagtggccaacagcaccacgtccagccgcagcaggaacaccacggccacc
gacgcctacaacatcaccgacccggaggagctggagacagagtaccctttctttgagagc
agagtggataacaaggagagaactgtcatttccaaccttcggcctttcacattgtaccgc
atcgatatccacagctgcaaccacgaagctgagaagctgggctgcagcgcctccaacttc
gtctttgcaaggactatgcccgcggaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgaaaactccatctttttaaagtggccggaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtg
tccagacaggaatacaggaagtatggaggggccaagctaaaccggctaaacccggggaac
tacacagcccggattcaggccacatctctctctgggaatgggtcgtggacagatcctgtg
ttcttctatgtccaggccaaaacaggatatgaaaacttcatccatctgatcatcgctctg
cccgtcgctgtcctgttgattgtgggagggttggtgattatgctgtacgtcttccataga
aagagaaataacagcaggctggggaatggagtgctgtatgcctctgtgaacccggagtac
ttcagcgctgcggatgtgtacgttcctgatgagtgggaggtggctcgggagaagatcacc
atgagccgggaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggt
gtggtgaaagacgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcaagc
atgcgtgaaaggatcgagtttctcaacgaagcttctgtgatgaaggagttcaattgtcac
catgtggtgcgattgctgggtgtggtgtcccaaggccagccaacactggtcatcatggaa
ctgatgacacggggcgatctcaaaagttatctccggtctctgaggccagaaatggagaat
aatccagtcctagcacctccaagcctaagcaagatgattcagatggccggagagattgca
gacggcatggcatacctcaacgccaacaaattcgtccacagagaccttgctgcccggaat
tgcatggtagccgaagatttcacagtcaaaatcggagattttggtatgacccgagatatc
tatgagacggactattaccggaaaggagggaaagggctgctgcctgtgcgctggatgtct
cctgagtccctcaaggatggagtcttcaccacttactcggacgtctggtcctttggggtc
gtcctctgggagatcgccacactggctgagcagccctaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctggacaagccagacaactgtcctgacatg
ctgtttgaactgatgcgtatgtgctggcagtataaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaagacgagatggagcctggcttccgggaggtctccttctac
tacagcgaggagaacaagctgcccgagccggaggagctggacctggagccagagaacatg
gagagcgtccccctggacccctcggcctcctcgtcctccctgccactgcccgacagacac
tcaggacacaaggccgagaatggccccggccctggagtgctggtcctccgcgccagcttc
gacgagagacagccttacgcacacatgaacgggggccgcaagaacgagcgggccttgccg
ctgccccagtcttcaacctgctga
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