Nomascus leucogenys (northern white-cheeked gibbon): 100595586
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Entry
100595586 CDS
T03265
Symbol
HTT
Name
(RefSeq) huntingtin
KO
K04533
huntingtin
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle05016
Huntington disease
nle05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
100595586 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
100595586 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
nle03019
]
100595586 (HTT)
04131 Membrane trafficking [BR:
nle04131
]
100595586 (HTT)
03029 Mitochondrial biogenesis [BR:
nle03029
]
100595586 (HTT)
Messenger RNA biogenesis [BR:
nle03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
100595586 (HTT)
Membrane trafficking [BR:
nle04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
100595586 (HTT)
Mitochondrial biogenesis [BR:
nle03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
100595586 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_GCN1
HEAT_2
HEAT_EF3_N
Rad26-like_helical_rpts
Motif
Other DBs
NCBI-GeneID:
100595586
NCBI-ProteinID:
XP_030657254
Ensembl:
ENSNLEG00000000273
LinkDB
All DBs
Position
20:complement(80539516..80709037)
Genome browser
AA seq
3130 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQQQQPPPPPPPPPPQLPQPPPQAQPLLPQPQPPPPPP
PPPPGPAVAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSVRNSPEFQKLLGIAMELF
LLCSDDAESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAE
LAHLVRPQKCRPYLVNLLPCLTRTSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLL
KAFIANLKSSSPTIRRTAAGSAVSICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLIL
GVLLTLRYLVPLLQQQVKDTSLKGSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNV
VTGALELLQQLFRTPPPELLQTLTTVGGIGQLTAAKEQSGGRSRSGSIVELIAGGGSSCS
PVLSRKQKGKVLLGEEEALEDDSESRSDVSSSALAASVKDEISGELAASSGVSTPGSAGH
DIITEQPRSQHTLQADSVDLAGCDLTSSATDGDEEDILSHSSSQVSAVPSDPAMDLNDGT
QASSPISDSSQTTTEGPDSAITPSDSSEIVLDGTDNQYLGLQIGQPQDEDEEATGILPDE
ASEAFRNSSMALQQAQLLKNTSHSRQPSDSSVDKFVLRDEATELGDQENKPCRVKGDIGQ
STDDDSAPLVHCVRLLSASFLLTGGKNVLVPDRDVRVSVKALALSCVGAAVALHPESFFS
KLYKVPLDTTEYPEEQYVSDILNYIDHGDPQVRGATAILCGTLICSILSRSRFHVGDWMG
TIRTLTGNTFSLADCIPLLRKTLKDESSVTCKLACTAVRHCVMSLCSSSYSELGLQLIID
VLTLRNSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGLLKLQERVLNNVV
IHLLGDEDPRVRHVAAASLIRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHETQPP
SHFSVSTITRIYRGYNLLPSITDVTMENNLSRVIAAVSHELITSTTRALTFGCCEALCLL
STAFPVCIWSLGWHCGVPPLSASDESRKSCTVGMATMILTLLSSAWFPLDLSAHQDALIL
AGNLLAASAPKSLRSSWASEEEANPAATKQEEVWPALGDRALVPMVEQLFSHLLKVINIC
AHVLDDVAPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEQASVPLSPKKGSEASAASRQ
SDTSGPVITSKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALD
VLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTLFGTNLASQFDGLS
SNPSKSQGRAQRLGSSSVRPGLYHYCFMAPYTHFTQALADASLRNMVQAEQEHDTSGWFD
VLQKVSTQLKTNLTSVTKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQKQVLDLL
AQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHSK
QIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVV
SMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQIADIILPMLAKQQMHIDSHEALG
VLNTLFEILAPSSLRPVDMLLRSMFVTPNTMASVSTVQLWISGILAILRVLISQSTEDIV
LSRIQELSFSPYLISCPVINRLRDGDCNSVLEEHSEGKQMKNLPEETFSRFLLQLVGILL
EDIVTKQLKVEMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAATRLFRSDGCGGSF
YTLDSLNLRARSMITTHPALVLLWCQILLLVNHTDYRWWAEVQQTPKRHSLSSTKLLSPQ
MSGEEEDSDLAAKLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLISLSH
EPPVQDFISAVHRNSAASGLFIQAIQSRCENLSTPTTLKKTLQCLEGIHLSQSGAVLTLY
VDRLLCTPFRVLARMVDILACRRVEMLLAANLQSSMAQLPMEELNRIQEYLQSSGLAQRH
QRLYSLLDRFRLSTMQDSLSPSPPVSSHPLDGDGHVSLETVSPDKDWYIHLVKSQCWTRS
DSALLEGAELVNRIPAEDMSAFMMNSEFNLSLLAPCLSLGMSEISGGQKSPLFEAAREVT
LARVSGTVQQLPAVHHVFQPDLPAEPAAYWSKLNDLFGDAALYQSLPTLARALAQYLVVV
SKLPSHLHLPPEKEKDIVKFVVATLEALSWHLIREQIPLSLDLQAGLDCCCLALQLPGLW
SVVSSTEFVTHACSLIHCVHFILEAVAVQPGEQLLSPERRTNTPKAIREEEEEVDPNTQN
PKYITAACEMVAEMVESLQSVLALGHKRNSGVPAFLTSVLRNIIISLARLPLVNSYTRVP
PLVWKLGWSPKPGGDFGTAFPEIPVEFLQEKEVFKEFIYRINTLGWTSRTQFEETWATLL
GVLVTQPLVMEQEESPPEEDTERTQINVLAVQAITSLVLSAMTVPVAGNPAVSCLEQQPR
NKPLKALDTRFGRKLSIIRGIVEQEIQAMVSKRENIATHHLYQAWDPVPSLSPATTGALI
SHEKLLLQINPERELGSMSYKLGQVSIHSMWLGNSITPLREEEWDEEEEEEADAPAPSSP
PTSPVNSRKHRAGVDIHSCSQFLLELYSRWILPSSSARRTPAILISEVVRSLLVVSDLFT
ERNQFELMYVTLTELRRVHPSEDEILAQYLVPATCKAAAVLGMDKAVAEPVSRLLESTLR
SSHLPSRVGALHGVLYVLECDLLDDTAKQLIPVISDYLLSNLKGIAHCVNIHSQQHVLVM
CATAFYLIENYPLDVGPEFSASIIQMCGVMLSGSEESTPSIIYHCALRGLERLLLSEQLS
RLDAESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKVSPGRTSDPNSAAPDSESVI
VAMERVSVLFDRIRKGFPCEARVVARILPQFLDDFFPPQDIMNKVIGEFLSNQQPYPQFM
ATVVYKVFQTLHSTGQSSMVRDWVMLSLSNFTQRTPVAMATWSLSCFFVSASTSPWVAAI
LPHVISRMGKLEQVDVNLFCLVATDFYRHQIEEELDRRAFQSVFEVVAAPGSPYHRLLTC
LRNVHQVPTC
NT seq
9393 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccctggaaaagctgatgaaggccttcgagtccctcaagtccttccagcagcag
cagcagcagcagcagcaacagccgccaccgccgccgccgccgccgccgcctcagcttcct
cagccgccgccgcaggcacagccactgctgcctcagccgcagccgcccccgccgccgccc
ccgccgccacccggcccggctgtggctgaggagccgctgcaccgaccaaagaaagaactt
tcagctaccaagaaagaccgtgtgaatcattgtctgacaatatgtgaaaacatagtggca
cagtctgtcagaaattctccagaatttcagaaacttctgggcatcgctatggaacttttt
ctgctgtgcagtgatgacgcagagtcagatgtcaggatggtggctgacgaatgcctcaac
aaagttatcaaagctttgatggattctaatcttccaaggttacagctcgagctttataag
gaaattaaaaagaatggtgcccctcggagtttgcgtgctgccctgtggaggtttgctgag
ctggctcacctggttcggcctcagaaatgcaggccttacctggtgaaccttctgccgtgc
ctgactcgaacaagtaagagacccgaggaatcagtccaggagaccctggctgcagctgtt
cccaaaattatggcttctttcggcaattttgcaaatgacaatgaaattaaggttttgtta
aaggccttcatagcgaacctgaaatcaagctcccccaccattcggcggacagcggctgga
tcagcagtgagcatctgccagcactcaagaaggacacaatatttctatagctggctacta
aatgtgctcttaggcttactggttcctgtcgaggatgaacactccactctgttgattctt
ggtgtgctgctcaccctgaggtatttggtgcccttgctgcagcagcaggtcaaggacaca
agcctgaaaggcagcttcggagtgacacggaaagaaatggaagtctctccttctgcagag
cagcttgtccaggtttatgaactgacgttacatcatacacagcaccaagaccacaatgtt
gtgactggagccctggaactgttgcagcagctcttcagaacgcctccacccgagcttctg
caaaccctgaccacagtcgggggcattgggcagctcaccgctgctaaggagcagtctggt
ggccgaagccgtagtgggagtattgtggaacttatagctggagggggttcctcatgcagc
cctgtcctttcaagaaaacaaaaaggcaaagtgctcttaggagaagaagaagccttggag
gatgactctgaatcgagatcggatgtcagcagctctgccttagcagcctcagtgaaggat
gagatcagtggagagctggctgcttcttcaggggtttccactccagggtcagcaggtcac
gacatcatcacagagcagccacggtcacagcacacactgcaggcggactcagtggatctg
gccggctgtgacttgacaagctctgccactgatggggatgaggaggatatcttgagccac
agctccagccaggtcagcgctgtcccatctgaccctgccatggacctgaatgatgggacc
caggcctcctcgcccatcagcgacagctcccagaccaccaccgaagggcctgattcagct
atcaccccttcagacagttctgaaattgtgttagacggtaccgacaaccagtatttgggc
ctgcagattggacagccccaggatgaagatgaggaagccacaggtattcttcctgatgaa
gcctcggaggccttcaggaactcttccatggcccttcaacaggcacagttattgaaaaac
acgagtcacagcaggcagccttctgacagcagtgttgataaatttgtgttgagagatgaa
gctactgaactgggtgatcaagaaaacaagccttgccgcgtcaaaggtgacatcggacag
tccaccgatgatgactctgcacctcttgtccattgtgtccgccttttatctgcttcgttt
ttgctaacagggggaaaaaatgtgctggttccggacagggatgtgagggtcagcgtgaag
gccctggccctcagctgtgtgggagcagctgtggccctccacccggaatctttcttcagc
aaactctataaagttcctcttgacaccacggaataccctgaggaacagtatgtctcagac
atcttgaactacatcgatcatggagacccacaggttcgaggagccactgccattctctgt
gggaccctcatctgctccatcctcagcaggtcccgcttccacgtgggagattggatgggc
accattagaaccctcacaggaaatacattttctttggcggattgcattcctttgctgcgg
aaaacactgaaggatgagtcttctgttacttgcaagttagcttgtacggctgtgaggcat
tgtgtcatgagtctctgcagcagcagctacagtgagttaggactgcagctgatcatcgat
gtgctgactctgaggaacagttcctattggctggtgaggacagagcttctggaaaccctt
gcggagatcgacttcaggctggtgagctttttggaggcaaaagcagaaaacttacacaga
ggggctcatcattatacagggcttttaaaactgcaagaacgagtgctcaataatgttgtc
atccatttgcttggggatgaagaccccagggtgcgacatgttgccgcagcatcattaatt
aggcttgtcccaaagctgttttataaatgtgaccaaggacaagctgatccagtagtggcc
gtggcaagagatcaaagcagtgtttacctgaaacttctcatgcatgagacacagcctcca
tctcatttctccgtcagcacaataaccagaatatatagaggctataacctactaccaagc
ataacagatgtcactatggaaaataacctttcaagagttattgcagcagtttctcatgaa
ctaatcacatcaaccacgagagcactcacatttggatgctgtgaagctttgtgtcttctt
tccactgccttcccagtttgcatttggagtttaggttggcactgtggagtgcctccactg
agtgcctcagatgagtctaggaagagctgtaccgttgggatggccacaatgattctgacc
ctgctctcgtcagcttggttcccattggatctctcagcccatcaagatgctttgattttg
gctggaaacttgcttgcagccagtgctcccaaatctctgagaagttcatgggcctctgaa
gaagaagctaacccagcagccaccaagcaagaggaggtctggccagccttgggggaccgg
gccctggtgcccatggtggagcagctcttctcccacctgctgaaggtgattaacatttgt
gcccacgtcctagatgacgtggctcctggacccgcaataaaggcagccttgccttctcta
acaaacccgccttctctaagtcccatccgacgaaaggggaaggagaaagaaccaggagaa
caagcatctgtaccgttgagtcccaagaaaggcagtgaggccagtgcagcttctagacaa
tctgatacctcgggtcctgttataacaagtaaatcctcatcactggggagtttctatcat
cttccttcatacctcaaactgcatgatgtcctgaaagctacacatgctaactacaaggtc
accttggatcttcagaacagcacggaaaagtttggagggtttctccgctcagccttggat
gttctttctcagatactagagctggccacactgcaggacattgggaagtgtgttgaagag
atcctaggatacctgaaatcctgctttagtcgagaaccaatgatggcaactgtttgtgtt
caacaattgttgaagactctctttgggacaaacttggcctcccagtttgacggcttatct
tccaaccccagcaagtcacaaggccgagcacagcgccttggctcctccagtgtgaggcca
ggcttgtaccactactgcttcatggccccgtacacccacttcacccaggccctcgctgac
gccagcctgaggaacatggtgcaggcggagcaggagcacgacacctcgggatggtttgat
gtcctccagaaagtgtctacccagttgaagacaaacctcacgagtgtcacaaagaaccgt
gcagataagaatgctattcataatcacattcgtttgtttgaacctcttgttataaaagct
ttaaaacagtacacgacaacaacatctgtgcagttacagaagcaggttttagatttgctg
gcgcagctggttcagttacgggttaattactgtcttctggattcagatcaggtgtttatt
ggctttgtattgaaacagtttgaatatattgaagtgggccagttcagggaatcagaagca
atcattccaaacatctttttcttcttggtattactatcttatgaacgctatcattcaaaa
cagatcattggaattcctaaaatcattcagctctgtgatggcatcatggccagtggaagg
aaggctgtgacacacgccataccggctctgcagcccatagtccacgacctctttgtatta
agaggaacaaataaagctgatgcaggaaaagagcttgaaacccaaaaagaggtggtggtg
tcaatgttactgagactcatccagtaccatcaggtgttggagatgttcattcttgtcctg
cagcagtgccacaaggagaatgaagacaagtggaagcgactgtctcgacagatagctgac
atcatcctcccaatgttagccaaacagcagatgcacattgactctcatgaagctcttgga
gtgttaaatacattatttgagattttggccccttcctccctccgtccggtggacatgctt
ttacggagtatgttcgtcactccaaacacaatggcatccgtgagcactgttcagctgtgg
atatcgggaattctggccattttgagggttctgatttcccagtcaactgaagatattgtt
ctttctcgtattcaggagctctccttctctccgtatttaatctcctgtccagtaattaat
aggttaagagatggggactgtaattcagtgctagaagaacacagtgaagggaaacaaatg
aagaatttgccagaagaaacattttcaaggtttctattacaactggttggtattctttta
gaagacattgttacaaaacagctgaaggtggaaatgagtgagcagcaacatactttctat
tgccaagaactaggcacgctgctaatgtgcctgatccacatcttcaagtctggaatgttc
cggagaatcacagcagctgccactagactgttccgcagtgatggctgtggcggcagtttc
tacaccctggacagcttgaacttgcgggctcgttccatgatcaccacccacccggccctg
gtgctgctctggtgtcaaatcctgctgcttgtcaaccacaccgactaccgctggtgggca
gaagtgcaacagaccccaaaaagacacagtctgtccagcacaaagttacttagtccccag
atgtctggagaagaggaggattctgacttggcagccaaacttggaatgtgcaatagagaa
atagtacgaagaggggctctcattctcttctgtgattatgtctgtcagaacctccatgac
tccgagcacttaacatggctcattgtaaatcacattcaagatctgatcagcctttcccac
gagcctccagtacaggacttcatcagtgccgttcatcggaactctgctgccagcggcctg
ttcatccaggcaattcagtctcgttgtgaaaacctttcaactccaaccacgctgaagaaa
actcttcagtgcttggaggggatccatctcagccagtcgggagctgtgctcacgctgtat
gtggacaggcttctgtgcactcctttccgtgtgctggctcgcatggtcgacatccttgct
tgtcgccgggtagaaatgcttctggctgcaaatttacagagcagcatggcccagttgcca
atggaagaactcaacagaatccaggaataccttcagagcagcgggctcgctcagagacac
caaaggctctattccctgctggacaggtttcgtctctccaccatgcaagactcacttagt
ccctctcctccagtctcttcccacccgctggatggggatgggcacgtgtcactggaaaca
gtgagtccggacaaagactggtacattcatcttgtcaaatcccagtgttggaccaggtca
gattctgcactgctggaaggtgcagagctggtgaatcggattcctgctgaagatatgagt
gccttcatgatgaactcggagttcaacctaagcctgctagctccatgcttaagcctaggg
atgagtgaaatttctggtggccagaagagtcccctttttgaagcagcccgtgaggtgact
ctggcccgcgtgagcggcaccgtgcagcagctgcctgctgtccatcatgtcttccagcct
gacctgcctgcagagccggcggcctactggagcaagttgaatgatctatttggggatgct
gcactgtatcagtccctgcccactctagcccgggccctggcacagtacctggtggtggtc
tccaaactgcccagtcatttgcaccttcctcctgagaaagagaaggacatcgtgaaattc
gtggtggcaacccttgaggctctgtcctggcatttgatccgtgagcagatcccgctgagt
ctggatctccaggcagggctggactgctgctgcctggccctgcagctgcctggcctctgg
agcgtggtctcctccacagagtttgtgacccacgcctgctccctcatccactgtgtgcac
ttcatcctggaggccgttgcagtgcagcctggagagcagcttcttagtccagaaagaagg
acgaataccccaaaagccatcagagaggaggaggaggaagtagatccaaacacacagaat
cctaagtatatcaccgcagcctgtgagatggtggcagaaatggtggagtctctgcagtcg
gtgttggccttgggtcataaaaggaatagcggtgtgccggcgtttctcacgtcagtgctt
aggaacatcatcatcagcctggcccgcctgccacttgtcaacagctacacacgtgtgccc
ccactggtgtggaagcttggatggtcacccaaaccgggaggggattttggcacagcattc
cctgagatccccgtggagttcctccaggaaaaggaagtctttaaggagttcatctaccgc
atcaacacactaggctggaccagtcgtactcagtttgaagaaacttgggccaccctcctt
ggtgtcctggtgacgcagcccctcgtgatggagcaggaggagagcccaccagaagaagac
acagagaggacccagatcaacgtcctggccgtgcaggccatcacctcattggtgctcagt
gcaatgaccgtgcctgtggccggcaacccagctgtaagctgcttggagcagcagccccgg
aacaagcctctgaaagctctcgacaccaggtttgggaggaagctgagcattatcagaggg
attgtggagcaagagattcaagcaatggtttcaaagagagagaacattgccacccatcat
ttataccaggcgtgggatcctgtcccttctctgtctccggctactacaggtgccctcatc
agccacgagaagctgctgctgcagatcaaccccgagcgggagctggggagcatgagctac
aaactcggccaggtgtccatacactccatgtggctggggaacagcatcacacccctgagg
gaggaggagtgggacgaggaagaggaggaggaggccgacgcccccgcaccttcgtcacca
cccacgtctccagtcaactccaggaaacaccgggctggagttgacatccactcctgttcg
cagtttttgcttgagttgtacagccgttggatcctgccgtccagctcagccaggaggacc
ccggccatcctgatcagtgaggtggtccgatcccttctagtggtctcagacttgttcact
gagcgcaaccagtttgagctgatgtatgtgacgctgacagaactgcgaagggtgcaccct
tcagaagacgagatcctcgctcagtacctggtgcctgccacctgcaaggcagctgccgtc
cttgggatggacaaggccgtggcggagcctgtcagccgcctgctggagagcacactcagg
agcagccacctgcccagcagggtcggagccctgcacggcgtcctctatgtgctggagtgc
gacctgctggacgacactgcgaagcagctcatcccagtcatcagcgactatctcctctcc
aacctgaaagggatcgcccactgcgtgaacattcacagccagcagcacgtactggtcatg
tgtgccactgcgttttacctgattgagaactatcctctggacgtagggccggaattctca
gcatcaataatacagatgtgtggggtgatgctgtccggaagtgaggagtccaccccctcc
atcatttaccactgtgccctcagaggcctggagcgcctcctgctgtctgagcagctctcc
cgcctggatgcagaatcgctggtcaagctgagcgtggacagagtgaacgtgcacagcccg
caccgggccatggcggctctgggcctgatgctcacctgcatgtacacaggaaaggagaaa
gtcagtccgggtagaacttcagaccctaattctgcagccccagacagcgagtcagtgatt
gttgctatggagcgggtatctgttctttttgataggatcaggaaaggctttccttgtgaa
gccagagtggtggccaggatcctgccccagtttctagatgacttcttcccaccccaggac
atcatgaacaaagtcatcggagagtttctgtccaaccagcagccatacccccagttcatg
gccaccgtggtgtataaggtgtttcagactctgcacagcaccgggcagtcgtccatggtc
cgggactgggtcatgctgtccctctccaacttcacgcagaggaccccggtcgccatggcc
acgtggagcctctcctgcttcttcgtcagcgcatccaccagcccgtgggttgcggcgatc
ctcccacatgtcatcagcaggatgggcaagctggagcaggtggacgtgaaccttttctgc
ctggtcgccacagacttttacagacaccagatagaggaggagctcgaccgcagggccttc
cagtctgtgtttgaggtggttgcagccccaggaagcccatatcaccggctgctgacttgt
ttacgaaatgtccaccaggtccccacctgctga
DBGET
integrated database retrieval system
