Nomascus leucogenys (northern white-cheeked gibbon): 100602214
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Entry
100602214 CDS
T03265
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521
EGFR tyrosine kinase inhibitor resistance
nle01522
Endocrine resistance
nle04012
ErbB signaling pathway
nle04015
Rap1 signaling pathway
nle04062
Chemokine signaling pathway
nle04137
Mitophagy - animal
nle04144
Endocytosis
nle04360
Axon guidance
nle04370
VEGF signaling pathway
nle04510
Focal adhesion
nle04520
Adherens junction
nle04530
Tight junction
nle04540
Gap junction
nle04611
Platelet activation
nle04613
Neutrophil extracellular trap formation
nle04625
C-type lectin receptor signaling pathway
nle04727
GABAergic synapse
nle04750
Inflammatory mediator regulation of TRP channels
nle04810
Regulation of actin cytoskeleton
nle04912
GnRH signaling pathway
nle04915
Estrogen signaling pathway
nle04917
Prolactin signaling pathway
nle04919
Thyroid hormone signaling pathway
nle04921
Oxytocin signaling pathway
nle04926
Relaxin signaling pathway
nle05100
Bacterial invasion of epithelial cells
nle05135
Yersinia infection
nle05152
Tuberculosis
nle05161
Hepatitis B
nle05163
Human cytomegalovirus infection
nle05167
Kaposi sarcoma-associated herpesvirus infection
nle05168
Herpes simplex virus 1 infection
nle05203
Viral carcinogenesis
nle05205
Proteoglycans in cancer
nle05207
Chemical carcinogenesis - receptor activation
nle05208
Chemical carcinogenesis - reactive oxygen species
nle05219
Bladder cancer
nle05417
Lipid and atherosclerosis
nle05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100602214 (SRC)
04015 Rap1 signaling pathway
100602214 (SRC)
04370 VEGF signaling pathway
100602214 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100602214 (SRC)
04137 Mitophagy - animal
100602214 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100602214 (SRC)
04520 Adherens junction
100602214 (SRC)
04530 Tight junction
100602214 (SRC)
04540 Gap junction
100602214 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100602214 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100602214 (SRC)
04613 Neutrophil extracellular trap formation
100602214 (SRC)
04625 C-type lectin receptor signaling pathway
100602214 (SRC)
04062 Chemokine signaling pathway
100602214 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
100602214 (SRC)
04915 Estrogen signaling pathway
100602214 (SRC)
04917 Prolactin signaling pathway
100602214 (SRC)
04921 Oxytocin signaling pathway
100602214 (SRC)
04926 Relaxin signaling pathway
100602214 (SRC)
04919 Thyroid hormone signaling pathway
100602214 (SRC)
09156 Nervous system
04727 GABAergic synapse
100602214 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100602214 (SRC)
09158 Development and regeneration
04360 Axon guidance
100602214 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100602214 (SRC)
05207 Chemical carcinogenesis - receptor activation
100602214 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
100602214 (SRC)
05203 Viral carcinogenesis
100602214 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
100602214 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
100602214 (SRC)
05168 Herpes simplex virus 1 infection
100602214 (SRC)
05163 Human cytomegalovirus infection
100602214 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
100602214 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
100602214 (SRC)
05152 Tuberculosis
100602214 (SRC)
05100 Bacterial invasion of epithelial cells
100602214 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100602214 (SRC)
05418 Fluid shear stress and atherosclerosis
100602214 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100602214 (SRC)
01522 Endocrine resistance
100602214 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nle01001
]
100602214 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nle04131
]
100602214 (SRC)
Enzymes [BR:
nle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100602214 (SRC)
Protein kinases [BR:
nle01001
]
Non-receptor tyrosine kinases
SRC family
100602214 (SRC)
Membrane trafficking [BR:
nle04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
100602214 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
100602214 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
100602214 (SRC)
Macropinocytosis
Kinases
100602214 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
100602214
NCBI-ProteinID:
XP_030682132
Ensembl:
ENSNLEG00000006271
LinkDB
All DBs
Position
13:complement(26634551..26695905)
Genome browser
AA seq
553 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPTENVHGAGGGAFPASQTPSKPASAEGHRGPGAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggacgccagccagcggcgccgcagtctggagccc
accgagaacgtgcacggcgctggcgggggcgctttccctgcctcgcagacccccagcaag
ccagcctcggccgaaggccaccgcggccccggcgcggccttcgcccccgcggccgccgag
cccaagctgttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcgggc
ccgctggccggtggagtgaccacctttgtggccctctatgactatgagtccaggacggag
acagacctgtccttcaagaaaggcgagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcccactcgctcagcacgggacagacaggctacatccccagcaactacgtggcgccctcc
gactccatccaggccgaggagtggtattttggcaagatcaccagacgggagtccgagcgg
ttactgctcaacgcggagaacccgagagggaccttcctcgtgcgagaaagtgagaccacg
aaaggtgcctactgcctctcagtgtcggacttcgacaacgccaagggcctcaacgtgaag
cactacaagatccgcaagctggacagcggcggcttctacatcacctcccgcacccagttc
aacagcctgcagcagctggtggcctactactccaaacacgccgatggcctgtgccaccgc
cttaccaccgtatgccccacgtccaagccgcagacgcagggcctggccaaggatgcctgg
gagatccctcgggagtcgctgcggctggaggtcaagctgggccagggctgctttggcgag
gtgtggatggggacctggaatggcaccaccagggtggccatcaaaaccctgaagcctggc
acgatgtctccagaggccttcctgcaggaggcccaagtcatgaagaagctgaggcatgag
aagctggtgcagttgtatgctgtggtttcggaggagcccatttacatcgtcacggagtac
atgagcaaggggagtttgctggactttctcaagggggagacgggcaagtacctgcggctg
cctcagctggtggacatggctgctcagatcgcctcgggcatggcgtacgtggagcggatg
aactatgtccaccgggaccttcgtgcagccaacatcctggtgggagagaacctggtgtgc
aaagtggccgacttcgggctggctcggctcattgaagacaatgagtacacggcgcggcaa
ggtgccaaattccccatcaagtggacggctccggaagctgccctctatggccgcttcacc
atcaagtcggacgtgtggtccttcgggatactgctgactgagctcaccacaaagggacgg
gtgccctaccctgggatggtgaaccgcgaggtgctggaccaggtggagcggggctaccgg
atgccctgcccgccggagtgtcctgagtccctgcacgacctcatgtgccagtgctggcgg
aaggagcctgaggagcggcccacctttgagtacctgcaggccttcctggaggactacttc
acgtccaccgagccccagtaccagcccggggagaacctctag
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