KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100602214
Entry
100602214         CDS       T03265                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521  EGFR tyrosine kinase inhibitor resistance
nle01522  Endocrine resistance
nle04012  ErbB signaling pathway
nle04015  Rap1 signaling pathway
nle04062  Chemokine signaling pathway
nle04137  Mitophagy - animal
nle04144  Endocytosis
nle04360  Axon guidance
nle04370  VEGF signaling pathway
nle04510  Focal adhesion
nle04520  Adherens junction
nle04530  Tight junction
nle04540  Gap junction
nle04611  Platelet activation
nle04613  Neutrophil extracellular trap formation
nle04625  C-type lectin receptor signaling pathway
nle04727  GABAergic synapse
nle04750  Inflammatory mediator regulation of TRP channels
nle04810  Regulation of actin cytoskeleton
nle04912  GnRH signaling pathway
nle04915  Estrogen signaling pathway
nle04917  Prolactin signaling pathway
nle04919  Thyroid hormone signaling pathway
nle04921  Oxytocin signaling pathway
nle04926  Relaxin signaling pathway
nle05100  Bacterial invasion of epithelial cells
nle05135  Yersinia infection
nle05152  Tuberculosis
nle05161  Hepatitis B
nle05163  Human cytomegalovirus infection
nle05167  Kaposi sarcoma-associated herpesvirus infection
nle05168  Herpes simplex virus 1 infection
nle05203  Viral carcinogenesis
nle05205  Proteoglycans in cancer
nle05207  Chemical carcinogenesis - receptor activation
nle05208  Chemical carcinogenesis - reactive oxygen species
nle05219  Bladder cancer
nle05417  Lipid and atherosclerosis
nle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100602214 (SRC)
   04015 Rap1 signaling pathway
    100602214 (SRC)
   04370 VEGF signaling pathway
    100602214 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100602214 (SRC)
   04137 Mitophagy - animal
    100602214 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100602214 (SRC)
   04520 Adherens junction
    100602214 (SRC)
   04530 Tight junction
    100602214 (SRC)
   04540 Gap junction
    100602214 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100602214 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100602214 (SRC)
   04613 Neutrophil extracellular trap formation
    100602214 (SRC)
   04625 C-type lectin receptor signaling pathway
    100602214 (SRC)
   04062 Chemokine signaling pathway
    100602214 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100602214 (SRC)
   04915 Estrogen signaling pathway
    100602214 (SRC)
   04917 Prolactin signaling pathway
    100602214 (SRC)
   04921 Oxytocin signaling pathway
    100602214 (SRC)
   04926 Relaxin signaling pathway
    100602214 (SRC)
   04919 Thyroid hormone signaling pathway
    100602214 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    100602214 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100602214 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    100602214 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100602214 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    100602214 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    100602214 (SRC)
   05203 Viral carcinogenesis
    100602214 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    100602214 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100602214 (SRC)
   05168 Herpes simplex virus 1 infection
    100602214 (SRC)
   05163 Human cytomegalovirus infection
    100602214 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100602214 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100602214 (SRC)
   05152 Tuberculosis
    100602214 (SRC)
   05100 Bacterial invasion of epithelial cells
    100602214 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100602214 (SRC)
   05418 Fluid shear stress and atherosclerosis
    100602214 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100602214 (SRC)
   01522 Endocrine resistance
    100602214 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nle01001]
    100602214 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:nle04131]
    100602214 (SRC)
Enzymes [BR:nle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100602214 (SRC)
Protein kinases [BR:nle01001]
 Non-receptor tyrosine kinases
  SRC family
   100602214 (SRC)
Membrane trafficking [BR:nle04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100602214 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    100602214 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    100602214 (SRC)
  Macropinocytosis
   Kinases
    100602214 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 100602214
NCBI-ProteinID: XP_030682132
Ensembl: ENSNLEG00000006271
LinkDB
Position
13:complement(26634551..26695905)
AA seq 553 aa
MGSNKSKPKDASQRRRSLEPTENVHGAGGGAFPASQTPSKPASAEGHRGPGAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggacgccagccagcggcgccgcagtctggagccc
accgagaacgtgcacggcgctggcgggggcgctttccctgcctcgcagacccccagcaag
ccagcctcggccgaaggccaccgcggccccggcgcggccttcgcccccgcggccgccgag
cccaagctgttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcgggc
ccgctggccggtggagtgaccacctttgtggccctctatgactatgagtccaggacggag
acagacctgtccttcaagaaaggcgagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcccactcgctcagcacgggacagacaggctacatccccagcaactacgtggcgccctcc
gactccatccaggccgaggagtggtattttggcaagatcaccagacgggagtccgagcgg
ttactgctcaacgcggagaacccgagagggaccttcctcgtgcgagaaagtgagaccacg
aaaggtgcctactgcctctcagtgtcggacttcgacaacgccaagggcctcaacgtgaag
cactacaagatccgcaagctggacagcggcggcttctacatcacctcccgcacccagttc
aacagcctgcagcagctggtggcctactactccaaacacgccgatggcctgtgccaccgc
cttaccaccgtatgccccacgtccaagccgcagacgcagggcctggccaaggatgcctgg
gagatccctcgggagtcgctgcggctggaggtcaagctgggccagggctgctttggcgag
gtgtggatggggacctggaatggcaccaccagggtggccatcaaaaccctgaagcctggc
acgatgtctccagaggccttcctgcaggaggcccaagtcatgaagaagctgaggcatgag
aagctggtgcagttgtatgctgtggtttcggaggagcccatttacatcgtcacggagtac
atgagcaaggggagtttgctggactttctcaagggggagacgggcaagtacctgcggctg
cctcagctggtggacatggctgctcagatcgcctcgggcatggcgtacgtggagcggatg
aactatgtccaccgggaccttcgtgcagccaacatcctggtgggagagaacctggtgtgc
aaagtggccgacttcgggctggctcggctcattgaagacaatgagtacacggcgcggcaa
ggtgccaaattccccatcaagtggacggctccggaagctgccctctatggccgcttcacc
atcaagtcggacgtgtggtccttcgggatactgctgactgagctcaccacaaagggacgg
gtgccctaccctgggatggtgaaccgcgaggtgctggaccaggtggagcggggctaccgg
atgccctgcccgccggagtgtcctgagtccctgcacgacctcatgtgccagtgctggcgg
aaggagcctgaggagcggcccacctttgagtacctgcaggccttcctggaggactacttc
acgtccaccgagccccagtaccagcccggggagaacctctag

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