KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100602682
Entry
100602682         CDS       T03265                                 
Symbol
CACNA1A
Name
(RefSeq) voltage-dependent P/Q-type calcium channel subunit alpha-1A isoform X1
  KO
K04344  voltage-dependent calcium channel P/Q type alpha-1A
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04020  Calcium signaling pathway
nle04721  Synaptic vesicle cycle
nle04723  Retrograde endocannabinoid signaling
nle04724  Glutamatergic synapse
nle04725  Cholinergic synapse
nle04726  Serotonergic synapse
nle04727  GABAergic synapse
nle04728  Dopaminergic synapse
nle04730  Long-term depression
nle04742  Taste transduction
nle04930  Type II diabetes mellitus
nle05017  Spinocerebellar ataxia
nle05032  Morphine addiction
nle05033  Nicotine addiction
nle05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100602682 (CACNA1A)
   04020 Calcium signaling pathway
    100602682 (CACNA1A)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    100602682 (CACNA1A)
   04727 GABAergic synapse
    100602682 (CACNA1A)
   04725 Cholinergic synapse
    100602682 (CACNA1A)
   04728 Dopaminergic synapse
    100602682 (CACNA1A)
   04726 Serotonergic synapse
    100602682 (CACNA1A)
   04730 Long-term depression
    100602682 (CACNA1A)
   04723 Retrograde endocannabinoid signaling
    100602682 (CACNA1A)
   04721 Synaptic vesicle cycle
    100602682 (CACNA1A)
  09157 Sensory system
   04742 Taste transduction
    100602682 (CACNA1A)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100602682 (CACNA1A)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    100602682 (CACNA1A)
  09165 Substance dependence
   05032 Morphine addiction
    100602682 (CACNA1A)
   05033 Nicotine addiction
    100602682 (CACNA1A)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100602682 (CACNA1A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:nle04040]
    100602682 (CACNA1A)
Ion channels [BR:nle04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   100602682 (CACNA1A)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 100602682
NCBI-ProteinID: XP_030676501
Ensembl: ENSNLEG00000013041
LinkDB
Position
10:57551061..57850243
AA seq 2508 aa
MARFGDEMPARYGGGGSGAAAGVVVGAGGGRGAGGSRQGGQPGAQRMYKQSMAQRARTMA
LYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQH
LPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTG
ILATVGTEFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIF
AIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQ
FDNILFAVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLIIIGSFFMLNLVLGVLS
GEFAKERERVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDVG
ALRRTTIKKSKTDLLNPEEAEDQLADIASVGSPFARASIKSAKLENSTFFHKKERRMRFY
IRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYAEFIFLGLFMSEMFIKMY
GLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIFKVTKYWAS
LRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDEGTPPTNFDTFPAAIM
TVFQILTGEDWNEVMYDGIKSQGGVQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLAN
AQELTKDEQEEEEAANQKLALQKAKEVAEVSPLSAANMSIAVKEQQKNQKPAKSVWEQRT
SEMRKQNLLASREALYNEMDPDERWKAAYTRHLRPDMKTHLDRPLVVDPQENRNNNTNKS
RAAEPTVDQRLGQQRAEDFLRKQARYHDRARDPSGSAGLDARRPWAGSQEAELSREGPYG
RESDHHAREGSLEQPGFWEGEAERGKAGDPHRRHVHRQGGSRESRSGSPRTGADGEPRRH
RAHRRPGEEGPEDKAERRARHREGSRPARGGEGEGEVPDGCERRRRHRHGAPATYEGDAR
REDKERRHRRRKENQGSGVPVSGPNLSTTRPIQQDLGRQDPPLAEDIDNMKNNKLATAES
AGPHDSLGHAGLPQSPAKMGNSTDPGPTPAIPAMATNPQNAASRRTPNNPGNPSNPGPPK
TPENSLIVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKE
EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI
ALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNILDFI
VVSGALVAFAFTSSTRGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLK
NVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVKARDRE
WKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMSIFYVVYF
VVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHMPQNKQSF
QYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSLFSLECVL
KVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFGNPNNFINLSFLRLFRAARLIKLLR
QGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQI
TEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVS
FIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAAWGRMPYLDMY
QMLRHMSPPLGLGKKCPARVAYKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGG
ADKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKAKK
LQAMREEQDRTPLMFQRMEPPSPTQEGGPGQNALPSTQLDPGGALMAHESGLKESPSWVT
QRAQEMFQKTGTWSPERGPPTDMPNSQPNSQSVEMREMGRDGYSDSEHYLPMEGQGRAAS
MPRLPAENQRRRGRPRGNNLSTISDTSPMKRSASVLGPKARRLDDYSLERVPPEENQRHH
QRRRDRSHRASERSLGRYTDVDTGLGTDLSMTTQSGDLPSKERDQERGRPKDRKHRQHHH
HHHHHHPPPPDKDRYAQERPDHGRARARDQRWSRSPSEGREHMAHRQGSSSVSGSPAPST
SGTSTPRRGRRQLPQTPSTPRPHVSYSPVIRKAGGSGPPQQQQQQQQAVARPGRAATSGP
RRYPGPTAEPLAGDRPPTGGHSSGRSPRMERRVPGPTRSESPRACRHGGARWPASGPHAS
EGPPGPRHHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPARHASSGATGRSPRTPRAS
GPACASPSRHGRRLPNGYYPAHGLARPRGPGSRKGLHEPYSESDDDWC
NT seq 7527 nt   +upstreamnt  +downstreamnt
atggcccgcttcggagacgagatgccggcccgctacgggggaggaggctccggggcagcc
gccggggtggtcgtgggcgccggaggcgggcgaggagccgggggcagccggcagggcggg
cagcccggggcgcaaaggatgtacaagcagtcaatggcgcagagagcgcggaccatggca
ctctacaaccccatccccgtccgacagaactgcctcacggttaaccggtctctcttcctc
ttcagcgaagacaacgtggtgagaaaatacgccaaaaagatcaccgaatggcctcccttt
gaatatatgattttagccaccatcatagcgaattgcatcgtcctcgcactggagcagcat
ctgcctgatgatgacaagactccgatgtctgaacggctggatgacacagaaccatacttc
attggaattttttgtttcgaggctggaattaaaatcattgcccttgggtttgccttccac
aaaggctcctacttgaggaatggctggaacgtcatggactttgtggtggtgctaacgggc
atcttggcgacagttgggacggagtttgacctacggacgctgagggcagttcgagtgctg
cggccgctcaagctggtgtctggaatcccaagtttacaagtcgtcctgaagtcgatcatg
aaggcgatgatccctttgctgcagatcggcctcctcctattttttgcaatccttattttt
gcaatcatagggttagaattttatatgggaaaatttcataccacctgctttgaagagggg
acagatgacattcagggtgagtctccggctccatgtgggacagaagagcccgcccgcacc
tgccccaatgggaccaaatgtcagccctactgggaagggcccaacaatgggatcactcag
ttcgacaacatcctgtttgcagtgctgaccgttttccagtgcataaccatggaagggtgg
actgatctcctctacaatagcaacgatgcctcagggaacacttggaactggttgtacttc
atccccctcatcatcatcggctccttttttatgctgaaccttgtgctgggtgtgctgtca
ggggagtttgccaaagaaagggaacgggtggagaaccggcgggcttttctgaagctgagg
cggcaacaacagattgaacgtgagctcaatgggtacatggagtggatctcaaaagcagaa
gaggtgatcctcgccgaggatgaaactgacggggagcagaggcatccctttgatgttgga
gctctgcggagaaccaccataaagaaaagcaagacagatttgctcaaccccgaagaggct
gaggatcagctggctgatatagcctctgtgggttctcccttcgcccgagccagcattaaa
agtgccaagctggagaactcaaccttttttcacaaaaaggagaggaggatgcgtttctac
atccgccgcatggtcaaaactcaggccttctactggactgtactcagtttggtagctctc
aacacgctgtgtgttgctattgttcactacaaccagcccgagtggctctccgacttcctt
tactatgcagaattcattttcttaggactctttatgtccgaaatgtttataaaaatgtac
gggcttgggacgcggccttacttccactcttccttcaactgctttgactgtggggttatc
attgggagcatcttcgaggttatctgggccgtcataaaacctggcacatcctttggaatc
agcgtgttacgagccctcaggttattgcgtattttcaaagtcacaaagtactgggcatct
ctcagaaacctggtcgtctctctcctcaactccatgaagtccatcatcagcctgttgttt
ctccttttcctgttcattgtcgtcttcgcccttttgggaatgcaactcttcggcggccag
tttaattttgatgaagggactcctcccaccaacttcgatacttttccagcagcaataatg
acggtgtttcagatcctgaccggcgaagactggaatgaggtcatgtacgacgggatcaag
tctcaggggggcgtgcaaggcggcatggtattctccatctatttcattgtactgacgctc
ttcgggaactacaccctcctgaatgtgttcttggccatcgctgtggataatctggccaac
gcccaggagctcaccaaggacgagcaagaggaagaagaagcagccaaccagaaacttgcc
ctacagaaagccaaggaggtggcagaagtgagtcctctgtccgcggccaacatgtccata
gctgtgaaagagcaacagaagaatcaaaagccagccaagtccgtgtgggagcagaggacc
agtgagatgcgaaagcagaacttgctggccagccgggaggccctgtataacgaaatggac
ccggacgagcgctggaaggctgcctacacccggcacctgcggccagacatgaagacgcac
ttggaccggccgctggtggtggacccgcaggagaaccgcaacaacaacaccaacaagagc
cgggcggccgagcccaccgtggaccagcgcctcggccagcagcgcgccgaggacttcctc
aggaaacaggcccgctaccacgatcgggcccgggaccccagcggctcggcgggcctggac
gcacggaggccctgggcgggcagccaggaggccgagctgagccgggagggaccctacggc
cgcgagtcggaccaccacgcccgggagggcagcctggagcagcccgggttctgggagggc
gaggccgagagaggcaaggccggggacccccaccggaggcacgtgcaccggcaggggggc
agcagggagagccgcagcgggtccccgcgcacgggcgcggacggagagccccgacgtcat
cgcgcgcaccgcaggcccggggaggagggcccggaggacaaggcagagcggagggcacgg
caccgcgagggcagccggccggcccggggcggcgagggcgagggcgaggttcccgacggc
tgcgagcgcaggaggcggcaccggcacggcgctccagccacttacgagggggacgcgcgg
agggaggacaaggagcggaggcatcggaggaggaaagagaaccagggctccggggtccct
gtgtcgggccccaacctgtcaaccacccggccaatccagcaggacctgggccgccaagac
ccacccctggcagaggacattgacaacatgaagaacaacaagctggccaccgcggagtcg
gccggtccccacgacagcctcggccacgccggcctgccccagagcccagccaagatggga
aacagcaccgaccccggccccacgccagccatccctgccatggccaccaacccccagaac
gccgccagccgccggacgcccaacaacccggggaacccgtccaatcccggcccccccaag
acccccgagaacagccttatcgtcaccaaccccagcggcacccagaccaattcagctaag
actgccaggaaacccgaccacaccacagtggacatcccgccagcctgcccgccccccctc
aaccacaccgttgtgcaagtgaacaaaaacgccaacccagacccactgccaaaaaaagag
gaagagaagaaggaggaggaggaagacgaccgtggggaagacggccctaagccaatgcct
ccctatagctccatgttcatcctgtccacgaccaacccccttcgccgcctgtgccattac
atcctgaacctgcgctactttgagatgtgcatcctcatggtcattgccatgagcagcatc
gccctggccgccgaggaccctgtgcagcccaacgcacctcggaacaacgtgctgcgatat
tttgactacgtttttacaggcgtctttacctttgagatggtgatcaagatgattgacctg
gggctcgtcctgcatcagggtgcctacttccgtgacctctggaatattcttgacttcata
gtggtcagtggggccctggtagcctttgccttcacgagcagtacacgtggcaatagcaaa
ggaaaagacatcaacacgattaaatccctccgagtcctccgggtgctacgacctcttaaa
accatcaagcggctgccaaagctcaaggctgtgtttgactgtgtggtgaactcgcttaaa
aacgtcttcaacatcctcatcgtctacatgctattcatgttcatcttcgccgtggtggct
gtgcagctcttcaaggggaaattcttccactgcactgacgagtccaaggagtttgagaaa
gattgtcgaggcaaatacctcctctacgagaagaatgaggtgaaggcgcgagatcgggag
tggaagaagtatgaattccattatgacaatgtgctgtgggctctgctgaccctcttcacc
gtgtccacaggagaaggctggccacaggtcctcaagcactcagtggacgccaccttcgag
aaccagggccccagccccgggtaccgcatggagatgtccattttctacgtcgtctacttt
gtggtgttccccttcttctttgtcaatatctttgtggccttgatcatcatcaccttccag
gagcaaggggacaagatgatggaggaatacagcctggagaaaaatgagagggcctgcatc
gatttcgccatcagcgccaagccgctgacccgacacatgcctcagaacaagcagagcttc
cagtaccgcatgtggcagttcgtggtgtctccgcctttcgagtacacgatcatggccatg
atcgccctcaacaccatcgtgcttatgatgaagttctatggggcttctgttgcttatgaa
aacgccctgagggtgttcaacatcgtcttcacctctctcttctctctggaatgtgtgctg
aaagtcatggcttttgggattctgaattatttccgcgatgcctggaacatcttcgacttt
gtgactgttctgggcagcatcaccgatatcctcgtgactgagtttgggaatccgaataac
ttcatcaacctgagctttctccgcctcttccgagctgcccggctcatcaaacttctccgt
cagggttacaccatccgcattcttctctggacctttgtgcagtccttcaaggccctgcct
tatgtctgtctgctgatcgccatgctcttcttcatctatgccatcattgggatgcaggtt
tttggtaacattggcatcgacgtggaggacgaggacagtgatgaagatgagttccaaatc
actgagcacaataacttccggaccttcttccaggccctcatgcttctcttccggagtgcc
accggggaagcttggcacaacatcatgctttcctgcctcagcgggaaaccgtgtgataag
aactctggcatcctgactcgagagtgtggcaatgaatttgcttatttttacttcgtttcc
ttcatcttcctctgctcgtttctgatgctgaatctctttgtcgccgtcatcatggacaac
tttgagtacctcacccgagactcctccatcctgggcccccaccacctggatgagtacgtg
cgtgtctgggccgagtatgaccccgcagcttggggccgcatgccttacctggacatgtat
cagatgctgagacacatgtctccgcccctgggtctggggaagaagtgtccggccagagtg
gcttacaagcggcttctgcggatggacctgcccgtcgcagatgacaacaccgtccacttc
aattccaccctcatggctctgatccgcacagccctggacatcaagattgccaagggagga
gccgacaagcagcagatggacgctgagctgcggaaggagatgatggcgatttggcccaac
ctgtcccagaagacgctagacctgctggtcacacctcacaagtccacggacctcaccgtg
gggaagatctacgcagccatgatgatcatggagtactaccggcagagcaaggccaagaag
ctgcaggccatgcgcgaggagcaggaccggacacccctcatgttccagcgcatggagcct
ccgtccccaacgcaggaaggaggacctggccagaacgccctcccctccacccagctggac
ccaggaggagccttgatggctcacgaaagcggcctcaaagagagcccctcctgggtgacc
cagcgtgcccaggagatgttccagaagacaggcacgtggagtccggaacgaggcccccct
accgacatgcccaacagccagcctaactctcagtccgtggagatgcgagagatgggcaga
gatggctactccgacagcgagcactacctccccatggaaggccagggccgggctgcctcc
atgccccgcctccctgcagagaaccagaggagaaggggccggccacgtgggaataacctc
agtaccatctcagacaccagccccatgaagcgttcagcctctgtgctgggccccaaggcg
cgacgcctggatgattactcgctggagcgggtcccgcccgaggagaaccagcggcaccac
cagcggcgccgcgaccgcagccaccgcgcctctgagcgctccctgggccgctacaccgac
gtggacacaggcttggggacagacctgagcatgaccacccaatccggggacctgccgtca
aaggagagggaccaggagcggggccggcccaaggatcggaagcatcgacagcaccaccac
caccaccaccaccaccaccccccgccccccgacaaggaccgctacgcccaggaacggccg
gaccacggccgggcacgggctcgggaccagcgctggtcccgctcgcccagcgagggccga
gagcacatggcgcaccggcagggcagtagttccgtaagtggaagcccagccccctcaaca
tctggtaccagcactccgcggcggggccgccgccagctcccccagaccccctccaccccc
cggccacacgtgtcctattcccctgtgatccgtaaggccggcggctcggggcccccgcag
cagcagcagcagcagcagcaggcggtggccaggccgggccgggcggccaccagcggccct
cggaggtacccaggccccacggccgagcctctggccggagatcggccgcccacggggggc
cacagcagcggccgctcgcccaggatggagcggcgggtcccaggcccgacccggagcgag
tcccccagggcctgtcgccacggcggggcccggtggccggcatctggcccgcacgcgtcc
gaggggcccccgggtccccggcaccacggctactaccggggctccgactacgacgaggct
gatggcccgggcagcgggggcggcgaggaggccatggccggggcctacgacgcgccaccc
cccgcacgacatgcgtcctcgggcgccaccgggcgctcgcccaggactccccgggcctcg
ggcccggcctgcgcctcgccttctcggcacggccggcgactccccaacggctactacccg
gcgcacggactggccaggccccgggggccgggctccaggaagggcctgcacgaaccctac
agcgagagcgacgatgattggtgctaa

DBGET integrated database retrieval system