Neomonachus schauinslandi (Hawaiian monk seal): 110571840
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Entry
110571840 CDS
T08474
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01521
EGFR tyrosine kinase inhibitor resistance
nsu04151
PI3K-Akt signaling pathway
nsu04217
Necroptosis
nsu04380
Osteoclast differentiation
nsu04550
Signaling pathways regulating pluripotency of stem cells
nsu04620
Toll-like receptor signaling pathway
nsu04621
NOD-like receptor signaling pathway
nsu04630
JAK-STAT signaling pathway
nsu04658
Th1 and Th2 cell differentiation
nsu04659
Th17 cell differentiation
nsu05140
Leishmaniasis
nsu05145
Toxoplasmosis
nsu05152
Tuberculosis
nsu05160
Hepatitis C
nsu05161
Hepatitis B
nsu05162
Measles
nsu05163
Human cytomegalovirus infection
nsu05164
Influenza A
nsu05165
Human papillomavirus infection
nsu05166
Human T-cell leukemia virus 1 infection
nsu05167
Kaposi sarcoma-associated herpesvirus infection
nsu05168
Herpes simplex virus 1 infection
nsu05169
Epstein-Barr virus infection
nsu05171
Coronavirus disease - COVID-19
nsu05200
Pathways in cancer
nsu05203
Viral carcinogenesis
nsu05212
Pancreatic cancer
nsu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
110571840 (JAK1)
04151 PI3K-Akt signaling pathway
110571840 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
110571840 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
110571840 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
110571840 (JAK1)
04621 NOD-like receptor signaling pathway
110571840 (JAK1)
04658 Th1 and Th2 cell differentiation
110571840 (JAK1)
04659 Th17 cell differentiation
110571840 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
110571840 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110571840 (JAK1)
05203 Viral carcinogenesis
110571840 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110571840 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
110571840 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110571840 (JAK1)
05161 Hepatitis B
110571840 (JAK1)
05160 Hepatitis C
110571840 (JAK1)
05171 Coronavirus disease - COVID-19
110571840 (JAK1)
05164 Influenza A
110571840 (JAK1)
05162 Measles
110571840 (JAK1)
05168 Herpes simplex virus 1 infection
110571840 (JAK1)
05163 Human cytomegalovirus infection
110571840 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
110571840 (JAK1)
05169 Epstein-Barr virus infection
110571840 (JAK1)
05165 Human papillomavirus infection
110571840 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
110571840 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110571840 (JAK1)
05140 Leishmaniasis
110571840 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110571840 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110571840 (JAK1)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
110571840 (JAK1)
Protein kinases [BR:
nsu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
110571840 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
110571840
NCBI-ProteinID:
XP_021535674
EnsemblRapid:
ENSNSCG00000008737
UniProt:
A0A2Y9GDB3
LinkDB
All DBs
Position
4:complement(52020799..52177834)
Genome browser
AA seq
1156 aa
AA seq
DB search
MQYLNIKEDCSAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLADREPLRLGSGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHPNDSGNILYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLESKHKKDEEKNKIR
EEWSNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT
LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLMKQAFFEAASMMRQVSHKHIVYLYGVCV
RDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTK
NLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWS
FGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFF
RAIMRDINKLEEQNPDIVSERKPAIEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEG
DNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEF
LPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVK
IGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYC
DSDYSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPRHCPDEVYQLMRKCWEFQPSN
RTTFQNLIEGFEALLK
NT seq
3471 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcagtgccatggctttctgtgctaaaatgagg
agctccaagaagaccgaggtgaatctggaggcccccgagccaggggtggaagtgctcttc
tatcttgctgatagggagcccctcaggctgggcagcggagagtacacggcggaggagctg
tgcatcagggccgcacaggaatgctgtatctctcctctgtgtcacaacctctttgccctg
tatgatgagaacaccaagctctggtatgccccgaatcgcaccatcactgttgatgacaag
acatcactccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat
gataatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa
aaaaaagtcccagatgcaacccctctccttgacgccagctctctggaatatctgtttgct
cagggacaatatgatttggtcaaatgcctggctcccattcgagaccccaagaccgagcag
gatgggcatgatattgagaacgaatgtctgggaatggctgtcctggccatctcccactac
gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcctgaaggaatttaacaataagactatttgtgacagcagt
gtatctactcatgacctaaaggtgaaatacctggccaccttggaaactttgacaaaacat
tatggcgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat
tggtttcatccgaatgatagtggaaatattctctactatgaagtgatggtaactggaaat
cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa
ctgaaacggaaaaaactggaaagtaaacacaagaaggatgaggagaaaaacaaaatccgg
gaagagtggagcaatttttcttacttccctgaaatcacccacattgtaataaaggagtct
gtggtcagcatcaataagcaggacaacaaaaaaatggaattgaagctctcgtcccacgaa
gaggccttatcctttgtgtcgctggtcgacggctacttccggctcacggcagatgcccat
cattacctctgcaccgatgtggctcccccactgatcgtccacaacatacagaatggttgt
cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggag
gggatgtatgtgctgaggtggagctgtaccgactttgacaatatcctcatgactgtcacc
tgctttgaaaaatctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag
gtgcagaagggccgctatagcctgcacggctcagaccgcagcttccccagcctgggggac
ctgatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaag
cgctgctgccagcccaagccccgagagatctccaatctgctggtggctactaagaaagct
caggagtggcagcctgtctaccccatgagccagctgagttttgaccggatccttaagaaa
gatattgtgcaaggcgagcaccttgggagaggcacacggacgcacatctactccggtacc
ctggtggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctgatgaagcaggccttctttgaagca
gccagcatgatgaggcaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtc
cgagacgtggagaatatcatggtggaggagtttgtggaaggcgggcccctggatctcttc
atgcaccggaaaagcgatgtcctcaccacaccatggaaattcaaagttgccaaacagctg
gccagcgccctgagttacttggaggataaagacctggtccatggaaacgtgtgcacaaaa
aaccttctcctggcccgcgagggtattgacagcgagtgcggcccgttcatcaagctcagt
gaccctggcatccccatcacagtgctgtccaggcaggagtgcatagaacgaatcccatgg
attgctcccgagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagc
tttggaaccacactctgggagatctgctacaatggcgagatccctctgaaagacaagacc
ctgattgagaaagagagattctacgaaagccggtgccggccagtgacaccatcttgtaag
gagctggctgaccttatgacccgctgcatgaactatgaccccaaccagagacccttcttc
cgagccatcatgagagacatcaataaactggaagagcagaatccagacattgtttccgaa
agaaagccggcaatcgaagtagatcccacacattttgaaaagcggttcttgaagaggatc
cgtgacttgggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggg
gacaataccggggagcaggtggcggtcaaatccctgaagcccgagagtggaggcaaccac
atagctgacctgaagaaggaaattgaaatcctaaggaacctctatcatgagaacattgtg
aagtacaaaggcatctgtacagaagacggaggaaatggtattaagctcatcatggaattt
ctgccttcaggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaa
cagcaattaaaatacgccgttcagatttgtaaggggatggactatttgggttctcggcag
tacgttcaccgggacttggcagcaagaaatgtcctcgttgagagtgagcaccaagtgaaa
attggagactttggtttgaccaaagcaattgaaactgacaaggagtactacacagtcaag
gatgatcgggacagccctgtgttttggtatgctcctgaatgtttaattcagtgtaaattt
tatatcgcctctgacgtctggtcgtttggagtgactctgcatgagctgcttacttactgt
gactcagattacagccccatggcgttgttcctgaaaatgataggcccaactcatggccag
atgacagtcacaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacgt
cactgtccagatgaggtttatcaacttatgagaaaatgctgggaattccaaccatccaat
cggacaacttttcagaaccttattgaaggatttgaagcacttttaaaataa
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integrated database retrieval system
