KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110576035
Entry
110576035         CDS       T08474                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform X1
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu03015  mRNA surveillance pathway
nsu04022  cGMP-PKG signaling pathway
nsu04024  cAMP signaling pathway
nsu04114  Oocyte meiosis
nsu04218  Cellular senescence
nsu04261  Adrenergic signaling in cardiomyocytes
nsu04270  Vascular smooth muscle contraction
nsu04390  Hippo signaling pathway
nsu04510  Focal adhesion
nsu04611  Platelet activation
nsu04720  Long-term potentiation
nsu04728  Dopaminergic synapse
nsu04750  Inflammatory mediator regulation of TRP channels
nsu04810  Regulation of actin cytoskeleton
nsu04910  Insulin signaling pathway
nsu04921  Oxytocin signaling pathway
nsu04931  Insulin resistance
nsu05031  Amphetamine addiction
nsu05034  Alcoholism
nsu05168  Herpes simplex virus 1 infection
nsu05205  Proteoglycans in cancer
nsu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    110576035 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    110576035 (PPP1CA)
   04024 cAMP signaling pathway
    110576035 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    110576035 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    110576035 (PPP1CA)
   04218 Cellular senescence
    110576035 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    110576035 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110576035 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110576035 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    110576035 (PPP1CA)
   04921 Oxytocin signaling pathway
    110576035 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110576035 (PPP1CA)
   04270 Vascular smooth muscle contraction
    110576035 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    110576035 (PPP1CA)
   04720 Long-term potentiation
    110576035 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110576035 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    110576035 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    110576035 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    110576035 (PPP1CA)
   05034 Alcoholism
    110576035 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    110576035 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    110576035 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nsu01009]
    110576035 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:nsu03021]
    110576035 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:nsu03019]
    110576035 (PPP1CA)
   03041 Spliceosome [BR:nsu03041]
    110576035 (PPP1CA)
Enzymes [BR:nsu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     110576035 (PPP1CA)
Protein phosphatases and associated proteins [BR:nsu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     110576035 (PPP1CA)
Transcription machinery [BR:nsu03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     110576035 (PPP1CA)
Messenger RNA biogenesis [BR:nsu03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     110576035 (PPP1CA)
Spliceosome [BR:nsu03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    110576035 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 110576035
NCBI-ProteinID: XP_021540788
UniProt: A0A2Y9GNF4
LinkDB
Position
11:5357994..5361515
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggaaagaatgtacagctaacagagaacgagatccgtggtctgtgcctc
aaatcacgggagatcttcctgagccagcccattcttctggagctggaggcgcccctcaag
atctgcggtgacatccatggccagtactacgaccttctgcggctatttgagtacggcggc
ttccctccagagagcaactacctcttcctgggggactatgtggaccggggcaagcagtct
ttggagaccatctgcctgctgctggcctataagatcaagtaccccgagaactttttcctt
ctgcgtgggaaccacgagtgtgccagcatcaaccgcatctacggcttctatgatgagtgc
aagagacgctacaacattaaactgtggaaaacctttaccgactgcttcaactgcctgccc
attgctgccattgtggacgagaagatcttctgctgccatggaggcctgtccccagacttg
cagtccatggagcagattcggcgtatcatgcggcccacagacgtgcctgaccagggcctg
ctatgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaatgac
cgtggtgtctcctttacctttggggctgaggtagtggccaagttcctgcacaagcacgac
ttggacctcatctgccgggcgcaccaggtggtggaagatggctatgagttctttgccaag
cggcagctggtgacactcttctcggctcctaactactgtggcgagtttgacaacgcaggt
gccatgatgagtgtggatgagacgctaatgtgctccttccagatcctcaagcccgctgac
aagaacaaggggaaatacgggcagttcagtggcttgaaccctggaggccggcccatcacc
ccgccccgcaactccgccaaagccaagaaatag

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