Nematolebias whitei (Rio pearlfish): 119418603 Help Entry 119418603         CDS       T08042                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism nwh  Nematolebias whitei (Rio pearlfish) Pathway nwh04020   Calcium signaling pathway nwh04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:nwh00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     119418603 (ryr3)    04020 Calcium signaling pathway     119418603 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:nwh04040]     119418603 (ryr3) Ion channels [BR:nwh04040]  Voltage-gated cation channels   Ryanodine receptor    119418603 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 Med16_bridge Motif Other DBs NCBI-GeneID:  119418603 NCBI-ProteinID:  XP_037541849 LinkDB All DBs Position 12:complement(41856474..42011553) Genome browser AA seq 4853 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSVATIQKEHRKFCLAAEGLGNRLCYLEPTSEAKYVPP DMCICNFVLEQSLSVRALQEMLANTGQSSEGSADHEKWAGQGGGHRTLLYGHAILLRHSF SGMYLTCLKTSRSLTDKLSFDVGLQEDSIGESCWWTIHPASKQRSEGEKVRIGDDLILVS VSTERYLHLSISISNIQVDASFMQTLWNVQPTCSSSNMAVGYLIGGHVMRLCHGHDESLT IPGADRSEEEQRIVNYEAGKGASKARSLWRLEPLRVSWSGSHIRWGQPFRLRHLSTGRYL ALTEDRGLVLEDREKSDTKATAFCFKPSKEKGDSGLKRDIDGMGAPEIKYGDSVCFVMHV ATGLWLSYLAPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESRAARIIRNTTFLF KNFIKALDSAAEGESNAVAGYVEEVLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQD LFKEEGMLSLLSICIDRMNLYNSAAHFGEMAGEEAGAAWKDILNLLYELLAALIRGNRNN CTQFSRKLDWLVNKLERLESSSGILEVLHCILVESPEALNIIQRGHIKSIISLLYKHGRN HKILDVLCSLCVCNGVAVRTNQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGIAEGS AQYKKWYFELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSF DGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGF FFPVVSFSAGVKARFLLGGRHGDFKFLPPASYSPCYEALLPKEKMHVEPVKEYKRDHDGV RDLLGTTQFLSQASFIPTPVDTSQIVLPPHLENIRDKLAENIHELWGMNKIELGWTYGKI RDDNKRQHPCLVDFTKLPETERSYNLQMSSETLKTLLALGCHVAQINVHAEDDLKKIKLP KDYLMSNGYKPAPLELSDVKLTAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSR RNPRLVPYALLDERTKKSNRDSLREAIRTIVGYGYEIDPPDQEVVHALDGQSIETIRFFR VEQTYAVKTGKWYFEFEVLTGGDMRVGWARPGCRPDVELGADDQAYVFDGYRGRRMHAGS RYFGQPWKKGDVVGCMINMEDKSMIFTLNGEILITSKGSELCFADFETEDGFIPVCSLGM SQIGHMNLGKNASTFKYYTMCGLQEGFEPFAVNTNREITMWFSKRLPTFFNVPQDHMHIE VTRIDGTVDNPPCLKVTHKTFGTQNSNNDMVYCRLSMPVEFYSADRVLDESLKLSHPPKE DGSIDYGTIHTYYHSVRVFAGQDPASVWVGWVTPDYHYYNKNFGLSKTQTVTVTLGDERG RVHESVQRSNCYMVCAADAVSPSSSSHSNSDLEIGCLIDLATGFVSFTANGTELPTVYQV EPNTKLFPAVFVRPTSSNLFQFEFVKIKDAMPLSSAIFRSEQRNPVPQCPPRLDVQTIVA VLWSRMPNTFLNVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDILELSEHEDLRKF HYHTLKLYSALCALGNNRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLISIHLET AKEARLMMNNEFIIPVTDETRSIKLFPDESKQHSLPGVGLSTSLTPRVNFSPVGIINTKR HQFLYSPQIPLGILKEKAISMLTEAVQGGGSHIRDPVGGSLEYQFVPILKLIGTLLIMGV LTSDEVRLILLLIEPNVFGEVKEGEEAKGDEVAGVREKEEVSKNEEKAVEAGEEETKESK PPAKSLLEKSLPESVKRQMCELLHYFCDCELKHRIESIVSFSDRFVSKLQFNQKFRYNEL MLALNMSAAVTAKKTKEFRSPPHEQINILLNFDAGEDCPCPEEVQDELKSFHEELRLHCG IPVDEEEEEQDTSIKGRLLALLYKIKGPPQKTEEEPKETEQAAPTNLKELISQTITSWAQ ESHIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAINLLASLGQIRSLLS VRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPK MVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNN GLALALEEPDLEKVVTYLAGCGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFVVFCNGE SVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPALDLPKAPTGAAPG LGEEEGEVIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTSDLV GIISIPLNMPVINKDGSVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLQMLEVGFL PDLKASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFANTEHYAQLVDSTLETIY RLSKGRSLTKAQRDAIEECLLAICRHLRPSMMQQLLRRLVFDVPMLAEYCKMPLRLLTNH YEQNWKYYCLPSGMAGFGMASEEELLLTKKLFWGIFDSLSQKKYDSELFKMAKSCLCAIA GALPPDFIDTSSGALEKQESVDAQGNFEPKPINTANISLPEKLEYVANKYAEHSHDKWAS EKMSAGWKHGDGVDEQGKTHPLLKPYKSLSEKERETYRWPVRESLKSMLAMNWNIERTKE GEAMFQQRESEKQRKLSLTQTNGFSPAPMDLDNITLSRELQGMMEVVAENYHNIWAKKKK SELFSKGEGLAHPLLVPYDTLTAKEKYRDKEKAQELFKFLQISGYAITRGLKDMEQDSSS MEKRFAYKFVKRLLKCVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLIDQTF KNHCLYFLSTPSKNLSSCGCASNKEKEMVTSLFCKMAALVRHRISLFGSDSANMVSCLHI LSHSLDTRTVMKSGAELVKAGFKSFFENAAEDLEKLVEMLKLGKFMQSRAQMKSVTQSIN YVTVALLPILTALFEHITTHEFGVDLLLDDVQLSCYRILMCFYSLGTGKNVFVERHLPAL GESLATLVGAVPVAFLEPHLNAYNPLSVFNTKTPRERAILSMPDTVEEMCPEMPRLDKLL KDVNDVSESGARYSDMPQVIEVVLPMLCNYLSYWWEKGPENSPPDADCCTMVTSEHLSII LGNILKILNNNLGIEDAPWMKRIAVYSQPIICKAGAGLLRSHFLPTLKKLKKKTVKVVSE EELLKADSKGDNQEAELLILDEFAILCRDLYAFYPMLIRYVDNNRSRWLKEPNADSTELF RMVAEIFILWCKSNNFKREEQNFVIQNEINNLGFLTGEGKTQMSKSGGDQERKHKRRRGE YYSIQTSLIVAALKKLLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKEFLLQNLHIQE KSDDPAVYWQLNLYKDVVVTSEGPADSERTVDRIQSISAAVFHLEQVEQPLRNKKCVGQK LLSKQRKRAVVACFRMAPLYNLPRHRAINLFIPAYERLWIEAEEYSFEEKLVQDLAKTPM KIVEEEEEETAEIRPDPLHQLILHFSHNALTERSHLEEDPLYIAYADMMAKSCAEDEEEE EEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGSMVTCTLKLGISI LNGGNVQVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGS IHTKRGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTMTVNIIISTVDYLLR LQESISDFYWYYSGKDIIDETGKLNFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRL WDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMV DTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPEFKGIISKKEFQKSMESQKQYSQ SEIEFLLSCAEADENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLATFLD LAESVLSYFEPYLGRIEILGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEG GESEKMEMFVNFCEDTIFEMQLASQISEPDIVEQPEEEEEEEGHSLLEELSEAEAQESLS AFSAACRSVKNKIAAVRQIFTVKNVRKQFKKIKKLSIRELITGFFSFFWMLFIGFFKGIF SLIFGFFHLIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVEGDKVEAIETSGS LDKTMTPTGDSSDMDVMLEMLTAPKKEGGKHVEPGLGDVSEQSADSSTADQKKKAAAKPT EAPDSEQEKADTENQEKEDKPKEEAAKEPAAEEKPRTKSSQPKEASPAFMSTIFAVLDVY LNKMLNYLARNFYNLRFLALFVCFAINFILLFYKVTGETDEEADEDDENTWGDEGDDENT LFDMDEFVLQESTGYMLPTLRFLAIFHTVISLLCLVGYYCLKVPLVVFKREKEIARKLEF DGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFIKRKVINKYGDMYGAERIAELLGL DKSALDFDPTVETVEKEASLLSWLSSIDTKYHIWKMGVVLTDNYFLYLIWYTTMSVFGHF NNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYN KSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDITFFFFV IVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHN LANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14562 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaggatgagatccaattcctgagaactgatgatgaagtg gtgctacagagtgtggccaccatccagaaggagcatcgcaagttttgcctggctgcagag ggactcggaaaccgcctgtgttacttggaacccacctctgaagctaagtatgttcctcca gacatgtgtatttgtaactttgtgctggagcagtccctgtcggtccgagccctgcaggaa atgctggctaacaccgggcaaagcagcgaagggagtgctgaccatgaaaaatgggcgggt caggggggtggacaccggaccctgctctacggtcacgccatcctcttacgccactccttc agtggcatgtacttgacctgtttgaagacatcaaggtcactgacagacaagctgtcattt gatgtcggactacaagaagactcgataggagagtcctgctggtggacgattcaccctgcg tccaagcagcggtccgaaggagagaaagttcgtattggagacgatctgattcttgttagc gtgtcgactgagagatacctgcatctctccatttctatcagcaacatccaggtggatgcc tccttcatgcagactctgtggaacgtgcagccgacctgctcatccagcaacatggccgta gggtatttgatcggtgggcatgtaatgcgtctgtgtcacggtcatgatgagagtctgacc attcctggagctgacaggagtgaagaagagcaaagaatagtgaattatgaggcaggaaag ggagcttcaaaagcccgctcactgtggagactggagcctcttcgggtcagctggagcggg agccatattcgatggggccagcctttccgtctacgtcatctctccactggtcgttatctg gcgttgactgaagaccgcggcctggtcctggaggacagagagaagtccgacaccaaggcc actgctttctgctttaagccatctaaggaaaagggtgactctggcctaaagagggacatc gatgggatgggagccccagagatcaagtacggagactccgtctgctttgtcatgcatgtg gcaactgggctgtggctttcttatctggcgcctgatgccaaatcatctcgcctcggtccc ctgaaaagaagggcctgccttcactctgagggccacatggatgatggcctcatcctccag cgctgccagcatgaagagtctcgagctgctcgcatcatccgaaacaccacattcctcttc aaaaacttcatcaaagctttggacagcgccgcagagggtgaaagcaacgcggtggccggg tacgtggaagaggtgctgcagaccctgaacgatctgatcgagtacttcaagcagcccgac tctgagctcgagcacgaggagaaacagtgtctgctccgttcgctcatcaaacgtcaagac ctcttcaaggaggagggcatgctgagcctcctgtccatttgcatcgaccggatgaacctg tacaacagtgcagcccattttggagagatggccggggaggaagctggtgcagcgtggaag gacattctcaacctcctttatgaactcttggctgctctgattcgtggaaacaggaacaac tgcacccagttctcccggaaattggactggctggtcaacaaactggagaggctggaatca tcatcgggaatcctggaagtcctccactgcatcttggtagaaagcccggaggctctgaac atcattcagagaggacatattaaatccatcatctctctgctctacaagcacggccgcaac cacaagattctggatgtcctgtgttctctctgtgtttgcaatggcgtggcagtgagaacc aatcagaacctgatctgcgacaaccttcttcctaagagggacctgctgcttcagacccga ctggttaatgatgttcaaagtatgagacccaacattttcctgggcatcgctgaaggttca gctcaatataagaagtggtacttcgagctggtcatcgatcaggtggaccactttgtgact ggcgagccgactcacctgcgtgtaggctgggccaacactaaaggctacgctccgtaccct ggtggaggagaggggtggggaggcaacggcgtgggtgatgacctgtactcctacagcttt gatggacttcatctctggtcaggtcgaatcccccgggctgttgcttccattaaccagcac ctgctgaactctgatgacgtggtcagctgctgtctggacttgggcgctcccagcatgtcc tttaggatcaatggtcagcctgtgcagggcatgttcgaggacttcaacacggatggattc ttcttccccgtcgtcagcttctctgcaggtgtaaaagctcgtttcctgttgggcggacgc cacggagatttcaagttcctgccacctgccagttactctccgtgctacgaagccctcctg ccaaaggagaagatgcacgtagagcctgtgaaggagtacaaacgggaccacgatggggtc cgcgatcttctgggaactacccagttcctctctcaggcctccttcattcccactcctgtt gacaccagccagattgttcttcctcctcatctggagaacatccgtgacaagctggcagaa aacatccatgaactttgggggatgaacaagattgaactgggctggacttatggcaagatc cgggatgacaacaagaggcagcacccttgccttgtggatttcaccaaactgcctgaaact gaacggagctacaatctgcagatgtccagcgaaacactcaagaccctgttggcactcggc tgccatgttgcccagattaatgttcatgctgaagatgatcttaagaaaatcaaattgcct aaagactacttgatgtctaacggttacaagcctgcgccactagaactctctgatgtgaaa ctgactgcgggtcaagaggttctagttgataaactggctgaaaacgcacacaacgtttgg gccaaagacagaataaaacaaggatggacctatggtatccagcaggatttgaagagcagg cgtaatcctcgcctggtgccatatgctttactggatgaacgcactaagaagtctaacaga gacagtctgagagaagccattaggaccattgttggatatggatatgaaatcgatcctcca gaccaggaggttgtgcatgcgttagatggtcagagcatcgagaccatccgcttcttccgt gtggagcaaacgtatgccgtgaagacggggaagtggtattttgagtttgaggtcctaact ggaggggacatgagggtcggctgggccagaccaggatgcagacccgacgtggagctgggc gcagatgaccaagcctacgtctttgatggatacaggggtcgacgaatgcacgccggcagc cgctactttgggcagccttggaaaaagggtgacgtggttggttgcatgatcaatatggag gacaaatccatgattttcaccctgaatggagagatcctgatcaccagcaagggttcagag ctttgcttcgccgactttgaaacagaggatggttttatcccagtctgcagcctcggcatg tcccagatcggccacatgaacctgggcaaaaacgcgagcacctttaagtactacaccatg tgtggtcttcaggagggttttgagccctttgctgtcaacacgaaccgagagattacaatg tggttcagcaagcgcttgcccacttttttcaacgtacctcaggaccacatgcacattgag gtgacgcggatcgatggaactgttgacaacccaccctgcctgaaggtcactcataagaca tttggaacccagaacagcaacaatgacatggtttactgcaggctgagcatgcctgtggag ttttactctgcagacagggtactggacgagtcactaaaactcagccatcctccaaaagaa gatggaagtattgactacgggaccatccatacttactaccactcggtgagagtgtttgcc ggacaggaccctgcctctgtgtgggtgggctgggtcacacccgattaccattactacaac aagaacttcggtctcagcaagactcaaaccgtcaccgtcaccctgggagacgagaggggc cgggtccacgagagcgttcagaggagtaactgctacatggtgtgcgcggccgacgccgtc agcccgtcctcctctagccattccaactcagacctggaaatcggctgtctgatcgacctg gccacgggcttcgtctccttcacagccaacggcaccgaattgcccacagtctatcaggtg gagccgaacaccaagctctttccagctgtttttgtacgccccaccagctcaaacctcttc cagtttgaatttgtcaagatcaaggatgccatgccgctgtcgtctgccatcttcagaagc gagcagaggaacccggttcctcagtgtccaccgagactggatgtgcagaccatcgtggcc gtgctctggagtcgaatgccgaacaccttcctgaatgtggagacggctcgggtcagtgaa cggcacggctgggtggtccaatgtctggagcccctgcagatgatggctgtgcacatacct gaagagaacaggtgtttggacatcctagagttatcagagcatgaggacctgaggaaattt cactaccacactctgaagttgtacagcgctctctgtgctctgggaaacaatcgtgtcgct cacgctctctgcagccatttagaccagtcgcagctcctctacaccatcgacaaccagtac ctgtcaggcatgctcagagagggcttctataatgtcctcatcagcattcatctcgagaca gcgaaggaggcgcgcctgatgatgaacaatgagttcattatccctgtgacagatgagact cgttccatcaaactcttcccagatgagtccaagcaacactcgctgcccggcgtgggcctc agcacctcccttacacctcgggtcaacttctcccccgtcggcatcatcaacaccaaacgc caccagttcctctacagcccccagatcccactgggcatcttgaaggagaaagccattagc atgctgacggaagccgtgcagggagggggctcgcacatccgagaccccgtgggcgggagt ttggagtatcagtttgttcccatcctgaagctcatcggaacgctgctcatcatgggggtc ctgaccagtgacgaggtgaggctgatcctcctcctgatcgagcccaacgtgttcggggag gtcaaggagggtgaggaggcgaagggggatgaggtggctggggtaagggagaaggaggag gtgagcaagaatgaggagaaggctgtggaggcgggggaggaggagaccaaggagagtaaa ccacctgctaaaagtctgctggagaagtcgctgccggagtccgtcaaacggcagatgtgc gagctgctgcattacttctgcgactgcgagctgaagcatcgcatcgaatccatcgtctcg ttctccgacagatttgtttccaagctgcagtttaatcagaagtttcgctacaacgagctg atgctggctctcaacatgtccgccgccgtcacggccaagaagaccaaggagttccgctcg ccgcctcacgagcagatcaatattctcctgaactttgacgcaggggaggactgtccctgt ccagaggaggtccaggatgagctcaagtccttccatgaagaattacgactccactgtgga atcccagtggatgaggaggaggaagagcaggacacgtctataaaaggccgtctgctggct ttgctctacaagattaaaggtccacctcagaagacagaagaagaacccaaagagacggag caggcggctccaaccaacctgaaggagctgatttctcagaccataaccagctgggctcag gagtcgcacatccaggacccagagctggtcagagtgatgttcagcctgctgaggaggcag tacgacggcatcggggaactgctgcgggccatgaagaaatcctacaccatcagcgccgca tccgtgcaggatgctattaacctgctggcctccctgggtcaaatcaggtctctgctttca gtgcgaatgggcaaagaggaggagaagctcatgatagatggactcggggacatcatgaac aataaagttttttaccaacatcccaacctgatgagagttctgggcatgcacgagaccgtc atggaggtcatggtcaatgttctgggaggagacaagtcccaggaaattgccttcccaaaa atggtggccagctgctgtcgattcttgtgctacttctgtcgtatcagccgtcagaaccag aaagccatgtttgaccaccttagctacctgctggagaacagcagcgttggactggcgtct gaggcgatgcggggctccactcctctggatgttgcagcatcttcggtgatggacaacaac ggcctggccctggctctggaggaacctgatctggagaaggtggtgacatacctggcagga tgcggtctgcagagctgtgccatgcttgttgccaagggttaccctgacctgggctggaac cccatagaaggagagcgctacctgtccttcctgagatttgtcgtcttctgcaatggtgag agtgtggaggaaaacgccaacgtggtggtgaagctgctgatccgacgccccgagtgtttt ggtcccgccctgaggggagagggaggacagggtctgctggccgccatgaaggaggcaatc aagatctctgaggatccagctctggacctgccgaaggcccccactggagccgctccaggg cttggagaggaggagggagaagttattcacatgggaaacgccatcatgtccttctactcg gccctcatcgacctgctggggcgctgcgctccagagatgcatcttatcaacgcaggtaaa ggtgaggcgctgcgtatcagagccatcctgcgctctctggttcccacgtcagacctggtg ggcatcatcagcatccccctcaacatgcccgtgattaataaagatggctcggtgacggaa ccggacatgtcggcttgtttctgtccggaccacaaggcccccatggtgctctttctggac agagtttacggcatcgaggaccagagcttcctgcttcagatgttggaggtcggcttcctg cctgacctcaaagcctcagcgtctttggacacggaagtgctgagcaccacggagacggca ttggccatgaaccgctacatcggctcagctctgctgcctctgctgacccgctgcgccgct ctgttcgccaacacggagcactacgctcagctggtcgactccacgctggagaccatctac cggctgtccaaaggtcgctcgctcaccaaagcccaacgggacgccatcgaggagtgtctg ctcgctatctgcaggcacctgcggccctctatgatgcagcagctgctcagacggctggtg ttcgatgtcccgatgctcgctgaatactgcaagatgcctctgcggctgctgaccaaccat tacgagcagaactggaagtactactgccttccttcagggatggccgggttcgggatggcc tcggaggaggaacttcttctcactaagaaactcttctggggaatcttcgactccctttct cagaagaagtatgattctgaacttttcaaaatggccaagtcctgcctgtgtgccatcgct ggagctctgcctccggacttcatagacaccagctcaggggccctggagaaacaggaatca gtggacgcgcagggcaactttgaacccaaacccatcaacactgccaatatttcccttcct gaaaaactcgagtacgttgctaacaagtatgccgagcattcccacgacaagtgggcctca gagaagatgtcagctggttggaaacacggagacggtgtggatgaacagggcaaaactcat ccactgctgaagccgtacaaatctttgagcgagaaggagagagaaacgtaccgctggcct gtgagggagtctttgaagagcatgttggccatgaactggaacatcgagagaaccaaagag ggcgaggccatgttccaacagcgcgagagcgaaaaacaacgaaagctctcgctgactcag actaacggcttcagcccggctccaatggacctcgacaacatcactttgtctcgagagtta cagggcatgatggaggtggttgcagaaaattaccacaacatctgggctaagaagaagaaa tccgagctgtttagcaaaggagaaggactggctcacccgctgctcgttccctacgacacc ctgactgccaaagagaagtacagagacaaagagaaagcccaggagctcttcaagttcctg cagataagtggctacgccatcacaaggggtttgaaggacatggagcaggactcgtcttcc atggaaaaacgttttgcctacaagttcgtcaagaggctgctgaaatgcgtcgactcggct caggagttcatcgctcatctcgaggccatggccaccagtggaaagactgataaatcacct cacgaccaggaaatcaagttctttgccaaggtgttgctaccattgattgatcaaacgttt aagaaccactgcctctacttcctgtccacacctagtaagaacctgagtagctgtggctgc gcctccaacaaggagaaggagatggtcaccagcctgttctgtaagatggcagctcttgtt agacacaggatttctctctttggaagtgattctgcaaatatggtgagctgtctgcacatc ctctcccactcactggacaccagaacagtgatgaagtctggagcagagctggtcaaagcc ggcttcaagtcattctttgagaatgcagccgaggacctggagaagctggtggagatgctg aagctggggaagttcatgcagtcacgtgcgcagatgaagagcgtcactcagagcatcaac tatgtgaccgtggctctgctgcccatcctcactgccctgtttgaacacatcaccactcac gaatttggagtggacctgcttttggatgatgtgcagctgtcgtgctaccgaatcctgatg tgtttctactctctgggaactggaaagaatgtctttgtggaaaggcatctgccggcgttg ggggagagtctggccaccctggtgggagctgtgcctgtggcattcctggagccccatctg aacgcttacaacccactttcagtcttcaacaccaagaccccccgagagagagccatcctg agcatgcccgacacggtggaggagatgtgtccagagatgcctcggctcgacaaactgctc aaagacgtcaacgatgtctcggagtccggcgctcgctacagcgacatgccacaggtcata gaggtggtcctgcccatgctgtgcaactacctgtcctactggtgggagaaaggtccggag aactcgcctcctgatgccgactgctgcaccatggtgacttctgaacacctcagcatcatt ctgggaaatattctcaagatcctcaacaacaacctcggcattgaagacgccccctggatg aagaggatcgcagtctactcacagccaatcatctgcaaagcaggagctggtttgttgaga tcccacttcctgccaacgctgaagaaactaaagaagaagacggtgaaggtggtgtctgag gaggagctgctgaaggccgacagcaaaggtgacaatcaggaggccgagctgctcatcctg gatgagtttgccattctctgcagggatctctatgctttttaccccatgctcatccgttac gtggacaacaacaggtccaggtggttgaaggagccgaacgcagactccactgagctcttc aggatggtggctgagatcttcatcctctggtgcaagtccaacaacttcaagcgtgaggag caaaactttgtgatccagaacgagatcaacaacctgggcttcttaaccggggagggcaag acacagatgtccaagtctggtggggatcaagagaggaaacacaaacgccgccgtggagaa tattactccattcagacgtctttgattgtagcggccctcaagaagctgctgcctatcggc ctgaacatgtgcaccccaggagaccaggagctcatctctctggccaagatacgctacagt ctgaaagacacagacgatgaggtgaaggagttcttgcttcagaatctccacattcaggaa aagtctgacgatccagcagtttactggcagctgaacctttacaaagacgtggtggtgacg agtgagggaccagcagactccgagcgcacagtggacagaatccagagcatctctgcagca gtcttccatctggagcaggttgagcaacctctgaggaacaagaagtgcgtgggccagaag ctgctgtccaaacagcgtaaacgggccgtggtggcttgtttccgcatggctccactttac aacctgcccaggcatcgtgctatcaacctcttcatcccggcctatgagagactttggata gaggcagaggagtactcctttgaggagaagctagttcaggatctggcaaaaacgccgatg aagatagtggaggaagaggaggaggagacggctgagatccggcctgaccctctgcaccaa ctcatcctccacttcagccacaacgctctgacggagaggagccacttggaagaagatcct ttatatatcgcatatgcagacatgatggcaaagagctgtgcagaggatgaggaagaagag gaagaagaagggaaggaaaaaacatttgaggaaaaggagatggagaagcagaaaatcctg tatcagcaggcgaggctgcacgctcgtggagccgctgaaatggtgctgcagatgatcagt gctagtaaaggtcgtttgggctccatggtgacctgcactctcaaactgggcatctccatc ctaaacggaggcaatgtgcaagttcagcagaaaatgctcgattacttgaaagagaaacga gacgcaggcttcttcaagagtctgtcaggactgatgcagtcttgcagtgtcctggatttg aacgcatttgagaggcaaaacaaagcagaaggacttggcatggtgacagaggaaggttca atccacactaagcggggctccaaggtgctccagaatgacgagttcaccaaagatctgttc cggtttttgcaacttctctgtgaggggcacaacggagatttccagaatttcctgagaacc caaactggaaatacaatgacggtcaacatcatcatcagcacggttgactatctgcttcgt cttcaggaatcaatcagtgacttttactggtattattctgggaaagatatcattgatgaa actgggaaacttaacttctccaaagctttgtctgtagccaagcagatcttcaactcactg actgagtacattcaggggccctgtattggaaaccagcagagtttagctcatagcagactg tgggacgcagttgtgggctttttgcacgtgtttgcaaacatgcagatgaagctgtcgcag gattccagtcaaattgagctgctgaaggagcttatggacttacagaaagacatggtcgtc atgttgctctctctccttgagggtaatgtggtgaacggaacaataggaaagcagatggtc gacactctggtggagtcttcgagtaacgtggagatgatcctgaagttctttgacatgttc ctcaagctgaaggatctcacaacgtccgacaacttcaaggagtacgacccggagttcaag ggcatcatttccaagaaggagttccagaagtcgatggagagccagaagcagtacagccag tcggagatcgaattcctgctctcgtgcgctgaggccgacgagaacgacatgtttaattac aaagaatttgtcgagcgcttccatgagccggccaaagatatcggcttcaacgtggcggtg ctgctgaccaacctctctgaacacatgccccacgactcccgactggccaccttcttagac ttggctgaaagcgtgctcagctacttcgagccttacctgggtcgtatcgaaatcttgggc agcgccaagcgcatcgagagggtttacttcgagatcagcgagtcgagccgtgagcagtgg gaaaagccgcaggtgaaggaatccaagcgtcagttcatcttcgacgtggtaaacgaggga ggagagagcgaaaagatggagatgtttgtgaatttctgcgaggacaccatctttgagatg cagctggcctcgcagatctccgaaccggacatcgtcgaacagcctgaagaggaggaggag gaggaaggacacagcctccttgaggagctttctgaagcggaggcgcaggagtcgctctcg gctttcagcgcggcgtgtcgctccgtcaagaacaagatcgcagcagtccggcagattttt accgttaaaaacgtacgcaagcagttcaagaaaatcaaaaagctgagcatcagggagctt atcacgggcttcttctctttcttctggatgcttttcatcggctttttcaaaggaattttc agcctcatctttggtttcttccaccttatctggtcctccatgttcggcggaggacttgtt gagggagccaagaacatgaaggtgacggacatcctcgggaacatgcccgaccccactcag tttggcatccatggcgacgtagaaggagataaagtggaagctatagagacatcgggaagc ttggacaaaactatgacaccaaccggagactcatcggatatggacgtcatgttggagatg ctaacggcgcccaaaaaggaaggaggcaaacacgtggagcctggcctgggtgacgtttct gagcagagcgccgattcctccactgcagaccaaaagaagaaagctgctgccaagcccact gaagccccggacagcgaacaagaaaaagccgacacagagaaccaggagaaggaggataaa ccgaaggaggaggcggctaaggagccagcggcagaggagaaacccaggaccaaatcaagt cagcctaaagaagcatctcctgccttcatgtccaccatatttgctgttcttgacgtctac ctgaacaagatgctgaactacctggctcgtaacttctacaacctccgtttcctggctctc ttcgtgtgctttgccatcaacttcatcctgctcttttacaaggttactggtgagacggat gaagaggctgatgaggatgatgaaaatacctggggggatgagggggatgatgagaacacg ctgtttgacatggacgagttcgtccttcaggagagcaccgggtacatgttacccacgctg cgcttcctggccatattccacacggttatctccctcctctgtctggtcgggtactactgt ctgaaggttcctttagtggttttcaagagggagaaggagatcgccaggaagcttgagttt gacggtttgtacatcactgagcagccgtcggacgacgacatcaaaggccagtgggatcgc ctcgtcatcaacacgccgtcgttcccgaacaactactgggacaaattcattaaacgcaag gtgatcaacaaatacggtgacatgtacggagctgaacgcatcgctgagcttctgggtctg gacaaaagtgctctggactttgaccccacggtggagactgtcgagaaggaagcttccctg ctttcatggttgagctctattgacacaaagtaccacatctggaaaatgggagtggttctg actgacaactacttcctgtatctgatctggtacaccaccatgtccgtctttggacacttc aacaactttttctttgctgctcatctgctggacatcgccatgggcttcaagactctccgc accatcctgtcttctgtcactcacaacgggaagcagctcgtgctgaccgtgggtctgctg gccgtggtcgtctacctctacaccgtggtggccttcaacttcttcagaaagttctacaat aagagcgaagacgaagacgagcccgacatgaagtgtgacgatatgatgacgtgctacttg ttccacatgtatgtgggcgtgagagctggaggtggtattggagacgagctggaggaccca gctggagatccttacgaactctaccgcatcctgtttgacatcactttcttcttctttgtc atcgtcatcctgctggccatcattcagggtttgattattgatgcctttggtgagctcaga gaccagcaggagcaggtgaaggaggacatggagaccaaatgcttcatttgtggcattggg aatgactactttgaccgaacgcctcacgggtttgaaacccacaccttacaagagcacaac cttgctaactacctgttcttcctcatgtacctgatcaacaaagatgaaactgaacacacg ggtcaggagtcgtacgtgtggaagatgtaccaggagagatgctgggacttcttccccaca ggagactgcttccgtaagcaatatgaggaccagctgggttag

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