KEGG   Ovis aries (sheep): 443130
Entry
443130            CDS       T03117                                 
Symbol
CAPN1
Name
(RefSeq) calpain-1 catalytic subunit
  KO
K01367  calpain-1 [EC:3.4.22.52]
Organism
oas  Ovis aries (sheep)
Pathway
oas04141  Protein processing in endoplasmic reticulum
oas04210  Apoptosis
oas04217  Necroptosis
oas04218  Cellular senescence
oas04382  Cornified envelope formation
oas05010  Alzheimer disease
oas05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:oas00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    443130 (CAPN1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    443130 (CAPN1)
   04217 Necroptosis
    443130 (CAPN1)
   04218 Cellular senescence
    443130 (CAPN1)
 09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    443130 (CAPN1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    443130 (CAPN1)
   05022 Pathways of neurodegeneration - multiple diseases
    443130 (CAPN1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:oas01002]
    443130 (CAPN1)
Enzymes [BR:oas01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.52  calpain-1
     443130 (CAPN1)
Peptidases and inhibitors [BR:oas01002]
 Cysteine peptidases
  Family C2: calpain family
   443130 (CAPN1)
SSDB
Motif
Pfam: Peptidase_C2 Calpain_III EF-hand_6 EF-hand_1 EF-hand_8 EF-hand_7 CAPN13-like_C_EFh
Other DBs
NCBI-GeneID: 443130
NCBI-ProteinID: NP_001120739
UniProt: B2ZA85
LinkDB
Position
21:39846271..39872811
AA seq 716 aa
MAEEFITPVYCTGVSAQVQKQRAKELGLGRHENAIKYLGQDYEQLRVHCLQRGALFRDEA
FPPVPQSLGFKELGPNSSKTYGIKWKRPTELFSNPQFIVDGATRTDICQGALGACWLLAA
IASLTLNDTLLHRVVPHGQSFQDGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHS
AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYNIILK
ALERGSLLGCSIDISSILDMEAVTFKKLVKGHAYSVTGAKQVNYQGQMVNLIRMRNPWGE
VEWTGAWSDGSSEWNGVDPYVREQLRIKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS
QRFRNWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEETDDPDPDDYGGRESGCS
FLLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFI
NLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTQELDDQVQANLPDEQVL
SEEEIDENFKSLFRQLAGEDMEISVKELRTILNRIISKHKDLRTTGFSVESCRSMVNLMD
RDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIEFAGFKLNKKLYEL
IITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
NT seq 2151 nt   +upstreamnt  +downstreamnt
atggccgaggagttcatcactccggtgtactgcaccggggtgtctgcacaagtgcagaag
cagcgggccaaggagctgggcctgggccgccatgaaaatgccatcaagtacctgggccag
gattacgagcagctgcgggttcactgcctgcaaaggggggcccttttccgtgatgaggct
ttccccccagtgccccagagcctgggcttcaaggagctgggccccaactcctccaaaacc
tatggcatcaagtggaagcgtcccacggagctgttctcaaacccccagttcatcgtggat
ggagccacccgcacagacatctgccagggcgcactgggggcatgttggcttctggctgcc
atcgcctcccttaccctcaatgacacgctcctgcaccgagtagttccacatggacaaagc
ttccaggatggctacgcgggcatcttccatttccagctgtggcagtttggtgagtgggtg
gatgtggtggtggatgacctgctgcccaccaaggacgggaagctggtgttcgtgcactct
gcccaaggcaacgagttctggagcgccctgctggagaaggcctatgccaaggtgaacggc
agctacgaggccctctcaggaggcagcacatctgagggctttgaggacttcaccggcgga
gtcaccgagtggtatgaactgcggaaggcgcccagcgacctctacaacatcatcctcaag
gccctggagcgcggctccctgctgggctgctccatcgatatctccagcattctggacatg
gaggctgtcaccttcaagaagctggtgaagggtcacgcctactctgtgactggggccaag
caggtgaactaccagggccagatggtgaacctgatccggatgcggaacccctggggcgag
gtggaatggacgggagcctggagtgacggctcctcggagtggaacggcgtggacccttac
gtgcgggagcagctccggatcaagatggaggatggggagttctggatgtcattccgagac
ttcatgcgtgaattcacccgcctggagatctgcaacctgacgcctgacgcactcaagagc
cagaggttccgcaactggaacaccaccctgtacgagggcacctggcggcgggggagcacc
gcggggggctgccgcaactacccagccactttctgggtgaacccccagttcaagatccgg
ctggaggagacggatgacccagaccccgacgactacgggggtcgcgagtcaggctgcagc
ttcttgctcgccctcatgcagaagcaccgccgtcgagagcgccgattcggccgtgacatg
gagaccataggtttcgctgtctacgaggtccctccggagctggtgggccagccggccgtg
catctgaagcgagacttcttcctggccaatgcctcccgggcccggtctgagcagttcatc
aacctgcgggaggtcagcacccgcttccgcctgccgcccggggagtacgtggtggtgccc
tctaccttcgagcccaacaaggaaggcgactttgtgctgcgtttcttctcagagaagagc
gcagggacccaagagctggatgaccaggtccaggccaatctccctgatgagcaagtgctc
tcagaagaggagattgatgagaacttcaagtctctcttcagacaactggcaggggaggac
atggagatcagcgtcaaggagctgcggaccatcctcaacaggatcatcagcaaacacaaa
gacctgcggaccacgggcttcagcgtggagtcctgccgcagcatggtcaacctcatggat
cgcgacggcaatggcaaactgggcctggtggagttcaacatcctatggaaccggatccgg
aattacctgtccatcttccggaagtttgacctggacaagtcgggcagcatgagtgcctac
gagatgcggatggccattgagtttgcaggcttcaagctcaacaagaagctgtacgagctc
attatcacccgctactcggagccagacctggccgtggacttcgacaactttgtgtgctgc
ctggtgcggctggagaccatgttccggtttttcaaaactctggacaccgatctggatgga
gtggtgacctttgacttgtttaagtggctacagctgaccatgtttgcatga

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