KEGG   Oreochromis aureus (blue tilapia): 116325347
Entry
116325347         CDS       T07295                                 
Symbol
cad
Name
(RefSeq) CAD protein
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
oau  Oreochromis aureus (blue tilapia)
Pathway
oau00220  Arginine biosynthesis
oau00240  Pyrimidine metabolism
oau00250  Alanine, aspartate and glutamate metabolism
oau01100  Metabolic pathways
oau01240  Biosynthesis of cofactors
Module
oau_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:oau00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    116325347 (cad)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    116325347 (cad)
   00220 Arginine biosynthesis
    116325347 (cad)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:oau01002]
    116325347 (cad)
Enzymes [BR:oau01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     116325347 (cad)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     116325347 (cad)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     116325347 (cad)
Peptidases and inhibitors [BR:oau01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   116325347 (cad)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   116325347 (cad)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 MGS Dala_Dala_lig_C ATP-grasp DHOase ATPgrasp_Ter Amidohydro_1 RimK ATP-grasp_3 Peptidase_C26 GARS_A GSH-S_ATP
Other DBs
NCBI-GeneID: 116325347
NCBI-ProteinID: XP_039454606
Ensembl: ENSOABG00000018718
LinkDB
Position
LG15:complement(20598491..20623235)
AA seq 2234 aa
MAKMATLILEDGTTFRGRQFGASMSVSGEVVFQTGMVGYPEALTDPSYRCQLLTLTYPLV
GNYGVPKDEKGEFGLSKWFESYKIHAAALIIGELSESPSHWSSTKSLDQWLKEQGIPGLQ
GVDTRCLTKKIREKGTMLGKLIVDGTPEESIPFDNPDKRNLVQEVSMKEPNVFNPSGSFR
ITVVDCGIKYNQIRCLAQRGARVTVVPWNHPLDTADFDGLFVSNGPGDPQLCEATINNVR
KVVSVDQPKPVFGICLGHQLLSLVIGAKTYKMKYGNRGHNQPCIHNGTERCFITSQNHGF
AVDPDTLPKDWDVLFTNANDHTNEGIVHNTKPLFSVQFHPEHMAGPTDLVSLFDVFIETV
KDHKEGNTGKSVKQRLMDHLTFTGSPKAEGHVRPKKVLILGSGGLSIGQAGEFDYSGSQA
IKALKEENIQTVLINPNIATVQTSKDLADKVYFLPITAEYVTQVIKNERPDGVLLTFGGQ
TALNCGVELTKLGILEKYKVQVLGTPVSSIEMTEDRKIFVEKMEEINEHVAPSEAALSVE
QAVAAAERLGYPVLVRSAFALGGLGSGFANNREELTSLVTAAFTHTSQVLVDKSLKGWKE
IEYEVVRDAYDNCVTVCNMENIDPLGIHTGESIVVAPSQTLNDREYNMLRNTAIKVIRHL
GIVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLGLGIPLPLLK
NSVTNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTKIGSSMKSVGEVMAIGRSFEEAFQK
ALRMVDENCVGFDHTIKPVSEKELQTPTDKRIFVLAAAFKAGYTVEKLYELTKIDRWFLH
KMKNIADHELLLETYNQDESTMPPEVMLKAKQLGFSDKQIALAVQSTELAVRKLRHDWSI
LPVVKQIDTVAAEWPAYTNYLYLTYHGTEDDLSFNDQHVMVIGSGVYRIGSSVEFDWCAV
GCITELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYERENPEGVILSMG
GQLPNNIAMSLHRQQCHILGTSPEFIDSAENRFKFSRMLDTIGISQPQWKELSDTESAVK
FCETVGYPCLVRPSYVLSGAAMNVAYSDGDLEKYLSNAVAVSKEHPVVISKFIQEAKEID
VDAVACDGVVMGIAISEHVENAGVHSGDATLVTPPQDLNQKTIERIMQIVHAIGQELQVT
GPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATQYIMGEDVEPVGLMKGK
GIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNIL
LSIGSYKNKSELLPTVQALESLGYDLYASMGTADFYTEHGVKVTAIDWPFEEYDSDECAT
KEKQRSIMNYLEENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRMAIDYSVPLIIDIKCT
KLFVQALRQIGRTPPVKTHIDSMASQTLVRLPGLIDVHVHLREPGATYKEDFSSGTAAAL
AGGVTLVCAMPNTSPAIIDANNLALVQKLAKAGSRCDYALYVGAATDNAALLPPIASQTA
GLKMYLNDTYSTLKMDNVSLWMEHFEKWPKQMPIVAHAEKQTVAAILMVAQLYQRPVHIC
HVAKKEEILIIRAAKQKGIQVTCEVAPHHLFLCEDNVAQIGDGRAQVRPMLGTREDMEAL
WENLDIIDCFATDHAPHSVDEKNSERPPPGYPGLETMLPLLLTAVSDGRLTLDDIIRRLY
DNPRKIFNLPVQENTYVEVDLEQEWVIPQAMQFTKSKWTPFEGMKVKGKVRRVVLRGEVA
YIDGQVLVPPGYGEDVKTWPTSSTHPPEPVKETPMTPERRRPTPPRDGVRTRAASPRRIG
GESRYLLPPRIHRASDPGLPPEMVMLPPAAAVDGYSHPPPLSRLLSPQSGSGQVPPGQVS
HLQMSPLLHPLVGQHILSVRQFSKEQISHLFNVAHSLRLMVQKERSLEILKGKVMASMFY
EVSTRTSSSFAAAMQRLGGSVIHFSEATSSSQKGESLADSVQTMSCYTDVLVLRHPTPGA
VESASRHCRKPVINAGDGVGEHPTQALLDVFTIREELGTVNGMTITMVGDLKHGRTVHSL
AKLLTQYRITLRYVAPKNLHMPAEIISYVASKGIKQEEFDSIEEALPDTDVLYMTRIQKE
RFASEEEYKACFDQFVLTPHIMTGAKQKMVVMHPLPRVNEISVEVDTDPRAAYFRQAENG
MYIRMALLATVLGR
NT seq 6705 nt   +upstreamnt  +downstreamnt
atggcaaagatggcaaccttgattttggaggacgggacgacgttcagaggccgccaattt
ggtgcaagcatgtcggtatccggagaagttgtgtttcagacggggatggtgggatacccc
gaggctcttactgatccatcctaccgctgccagctgctgaccctcacttaccctctggtt
ggcaactacggtgtgccgaaggatgaaaagggagagtttgggctgagcaagtggtttgag
tcatacaagatccacgctgctgctttgattattggagaactgtctgaaagtcccagtcac
tggagttcaaccaagtcactggaccagtggctcaaagagcaaggcattcctggattacaa
ggtgttgacacccgctgcttgaccaaaaagatcagagagaaggggaccatgttggggaag
ctgatagtggatgggactcctgaggaaagtattcccttcgataatcccgacaagaggaac
ctggtccaagaggtctccatgaaggagccaaacgtgttcaatcctagcggcagctttcgt
atcacagtggtggactgtggcatcaagtacaaccagatccgctgcctggctcagagagga
gcccgcgttactgtagtgccctggaaccacccgctggacaccgccgattttgatggtttg
ttcgtcagtaatggtcccggggatccccagctctgtgaggccaccatcaacaacgtaagg
aaggtggtctctgtggaccaaccaaagccagtttttggcatctgtctcggacaccagctg
ctctctctggtcatcggagccaagacctacaagatgaagtatggtaaccgtggacacaac
caaccgtgcatccataatgggacagagcgctgcttcatcaccagtcagaatcacggcttc
gctgtcgaccctgatactttacccaaagactgggacgtgctcttcacaaatgctaacgac
cacaccaacgagggcatcgtacacaacacaaagcctctgttcagtgttcagttccaccca
gagcacatggctgggcctacagatctggtcagcctgtttgatgtcttcatagaaacggtg
aaagaccataaagagggcaacaccggaaaatctgtgaagcagcgtctgatggaccacctc
actttcactggttccccaaaggctgaagggcatgtcagacccaagaaagtcctcatccta
ggctcaggtggactgtccatcggccaggctggagagtttgattactccggctcgcaggct
attaaggctctgaaggaagagaatatccagactgtgttgatcaatcccaacattgccact
gtccagacctccaaagatctggctgacaaagtctactttctgccgattacagcagagtac
gtcactcaggtgataaaaaatgagcgcccggacggcgtcctgctgacttttggaggtcag
actgctctgaactgcggtgtagagctgaccaagctgggcatcctggagaagtataaggtg
caggttctgggaactcctgtttcctccattgagatgaccgaagacaggaaaatctttgtg
gagaaaatggaagagatcaatgagcatgtagctcccagtgaagcagctctgtcggtggaa
caggcggtggcggctgctgagcgtcttggctaccccgtcttggttcgttcagcgttcgct
ctcggaggcctcggctccggctttgccaacaacagagaggagctgacctctctggtaacg
gcagcattcactcacacctctcaggtactggtggacaaatccctgaaaggctggaaggag
attgagtacgaggtggtccgggatgcctatgacaactgtgtgactgtgtgtaatatggag
aacatcgaccccctcggtatccacactggggaatccattgtagtggctcccagtcagacg
cttaacgaccgcgagtacaacatgctgagaaacacggccattaaagtcatcagacatctt
ggcatcgtgggagagtgtaacatccagtacgctcttaaccccgaatctgaacagtactac
atcattgaggtgaatgcccgcctgtcacggagctccgctctggccagtaaagcgactggt
tatcctttggcctacgtagcagctaaacttggtctggggatcccgctgccgctgctcaaa
aactcagtcacaaactcgacgacggcaaactttgagccgagtttggactactgtgtggtg
aaggtgcctcgctgggatctcagcaagttcctcagggtttcgaccaagataggcagctcc
atgaagagtgttggggaggtgatggctattggtcgtagctttgaggaagccttccagaaa
gctctgaggatggtggatgagaactgtgttggcttcgaccacaccatcaagcctgtctct
gaaaaggagttgcagactcccacagataagcgtatctttgtgctggcggcagcgttcaaa
gctggctacactgtggaaaagctgtatgagctgaccaaaatcgaccgctggttcctgcac
aagatgaagaacatcgccgaccacgagctgctgctggagacctacaatcaggatgagagc
accatgcctccagaggtgatgcttaaggccaagcagctgggcttctcagacaagcagata
gcactggctgtacagagcacagagctggccgtcagaaagctgcgtcacgattggtccatc
ctgccagtggtgaagcaaattgacacagtggcggctgaatggccggcttacacaaactac
ctgtacctgacctaccacggcacagaggacgacctgagcttcaacgatcagcacgtcatg
gtgatcggctcgggcgtgtaccgcatcggcagcagcgtggagtttgattggtgcgctgtt
gggtgcatcacagagctcaggaagatgggctataagaccatcatggtgaactacaacccc
gagacagtcagcacagactacgacatgtgtgaccggctctacttcgacgagatctccttt
gaggtggtgatggacatctatgaaagggaaaacccagagggagtgatcctctctatggga
ggccagcttcccaacaacattgccatgtcgttgcaccgccagcagtgccacatcttgggg
acttcgcccgagttcatcgacagcgctgagaaccggttcaagttctcccgaatgctggac
accatcggcatcagccagccgcagtggaaggagctctcagacactgagtctgctgtgaag
ttttgcgagacggtcggttatccctgcctcgttcgcccctcgtatgttctgagcggcgcg
gccatgaacgtcgcctacagcgatggcgacctcgagaaatacctgagtaacgctgtagca
gtgtccaaggaacaccctgtggtcatctctaaattcattcaggaggctaaggagatagac
gtggacgctgtggcatgtgacggtgtagtgatgggcattgcgatttctgaacacgtggag
aacgctggagttcactctggtgacgccaccttggtgacaccgcctcaggacctcaatcag
aaaaccatagagaggatcatgcagatcgttcacgccatcggtcaggagctgcaagtcacc
gggccatttaacctgcagttaattgcaaaggatgaccagctcaaagtgatcgagtgcaac
gtccgagtttctcgctccttcccctttgtgtccaagacactgggagtggacttggtggct
ctggctacccagtacattatgggggaggacgtggagccagtgggcctgatgaaagggaaa
gggattgtgggcgtcaaggtccctcagttttctttctctcggctggccggagctgatgtg
gtgctcggggtggagatgaccagcaccggagaagtagcctgttttggggagaaccggtac
gaggcttacctcaaagccatgctctccacaggcttcaagatccccaagaagaacatcctg
ctctccatcggcagctataagaacaagagtgagctgctgcccaccgtgcaggccctggag
tctttgggatatgacctgtatgccagtatgggcacggctgacttctacacagagcatgga
gtcaaggtgactgcaatcgattggccgtttgaggagtacgacagcgatgaatgcgccacc
aaagagaagcagcgcagcatcatgaactacctggaggagaaccacttcgaccttgtcatt
aacctctccatgaggaacagcggaggtcgaaggctctcctcctttgtcaccaaaggctac
aggaccaggcgtatggctatcgactactccgtccccctcatcatcgatatcaagtgcacc
aagctctttgttcaggctcttcgtcagattggaaggactccaccagtgaaaactcatatt
gacagcatggcatcccagacactcgtccgtctgccgggtctgatcgatgtccacgttcac
ctacgggagcctggcgccacctataaggaggacttctcctcaggcacagcagctgctctg
gcaggaggagtgaccctggtgtgtgcgatgcccaacacttcccccgccatcattgatgct
aataatctggctctggtccagaagttagccaaagcaggaagccgctgcgactacgccctg
tatgtgggcgctgccacggacaatgctgctctcctgccgcccatcgccagccagaccgcc
ggtctgaagatgtacctgaatgacacgtactccaccctcaagatggacaacgtctccctg
tggatggagcactttgagaaatggcccaagcagatgcccatcgtggctcacgctgagaag
cagacggtggcggcgatcctcatggtggcccagctgtaccagcgacctgtccacatctgc
cacgtggccaagaaagaggagatcctgataatccgtgctgcgaagcagaagggcatccag
gtcacatgcgaggtcgcccctcaccacctcttcctgtgcgaggataatgtggcgcagatc
ggcgacggtcgagcgcaggttcgacccatgctgggaacacgcgaggacatggaggcactc
tgggaaaatctggacattatcgactgctttgctacagaccatgctcctcactctgtagac
gagaagaacagtgagcgtcctcctcctggttaccccggtctggaaacaatgctgcctctg
ctgctcaccgccgtcagtgatggacgtctgactctggatgatattatcagacgtctttat
gacaatccacgcaagatcttcaacctgcccgttcaggaaaacacctacgtggaggtggac
ctggagcaggagtgggttattcctcaggccatgcagttcactaagtctaagtggactccc
tttgaaggtatgaaggtgaaaggtaaagttcgccgcgtggtcctgcgaggagaggtggcc
tacatcgacggccaggtgctcgtgcctccaggttacggtgaggatgtgaagacttggccc
acttcttccacccatcctccagaacctgtcaaagaaactccaatgactcctgagcgtcgg
cgtccaactccaccccgggatggagtgcggactcgagctgcgagcccacgacgcattggt
ggagaaagccgctacctgctgccgccccgcatccaccgtgcctctgatcctggactgcca
ccagagatggtcatgctcccaccagccgctgctgttgacggttacagccatcctccccca
ctgtccaggctgctgtccccacagtctgggtcaggacaggtgcctcctggtcaggtgtca
cacctgcagatgtctcctctgcttcacccactggtgggacagcacatcttgtctgtcaga
cagttcagcaaggagcagatctcacacctgttcaatgttgctcactctttacgtttgatg
gttcagaaggaacgaagcctggaaatactcaagggtaaagtaatggcctccatgttctat
gaggtcagcactcgcaccagcagttccttcgcagcggccatgcagcgtttgggcggctcc
gtcatccatttcagcgaggccacttcctcctcgcagaagggagaatcgctggcggactct
gtccagaccatgagctgctacactgacgtcctcgtgctgcgtcacccaacacctggagct
gtagagagcgcgtcccgtcattgccgtaagccggtgatcaatgctggcgatggtgtcggg
gagcatcccactcaggccctgttggacgtcttcaccatcagagaggagctgggaacggtc
aacggcatgacgataacgatggttggagatctgaaacatggccgcacggttcattccctc
gccaaactgctgacccagtaccgcatcaccctgcgctacgtggctcccaaaaacctccac
atgccagcagagatcatcagctacgtagcctcaaagggcatcaaacaggaggagtttgac
agcatcgaggaggctctgcctgacaccgacgtcctctacatgacgaggatccagaaggag
aggtttgcgtctgaggaggaatacaaagcctgttttgatcagttcgtcctcactcctcac
atcatgactggagccaaacagaagatggtagtgatgcacccgctgcccagagtcaatgaa
atcagtgtggaggtggacacagacccgagggcggcatatttccgtcaggcggagaatggc
atgtacatccgaatggccctgctggccaccgtactgggccgataa

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