Afipia carboxidovorans OM5 (Goettingen): OCA5_c15420
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Entry
OCA5_c15420 CDS
T01617
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ocg
Afipia carboxidovorans OM5 (Goettingen)
Pathway
ocg00290
Valine, leucine and isoleucine biosynthesis
ocg00620
Pyruvate metabolism
ocg01100
Metabolic pathways
ocg01110
Biosynthesis of secondary metabolites
ocg01210
2-Oxocarboxylic acid metabolism
ocg01230
Biosynthesis of amino acids
Module
ocg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ocg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
OCA5_c15420
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OCA5_c15420
Enzymes [BR:
ocg01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
OCA5_c15420
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
MAP1B_neuraxin
Motif
Other DBs
NCBI-ProteinID:
AEI06258
UniProt:
B6JHT5
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Position
1667814..1669412
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AA seq
532 aa
AA seq
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MSRERLYLFDTTLRDGAQTQGVGFSLHDKRIIAQMLDELGVDYIEGGYPGANPADSEFFS
ERPKFSHAKFVAFGMVRRSGRSVSNDPGLAAVLAAKTDAFCLVAKASAYQVRVALETTNE
ENLAAIRDSISAAVAKSGTAMLDCEHFFDGYKEDPAFALACAKAAYESGARWVVLCDTNG
GTLPHEVEAIVGEVTKHIPGSHLGIHAHDDTGQGVANSLAAVRAGVRQIQGTLNGLGERC
GNANLCSLIPTLKLKKPFCDTLEINVTDAKLATLTQVSRALDEILNRAPNKHAPYVGESA
FVTKTGIHASAVLKDPHTYEHIVPELVGNHRQVLVSDQAGRSNVLAALERAGIAFDKSDP
KVTRLVEEMKEREAGGYSYESAEASFELLARRTLGHVPDYFRVLQFDVNVEQRTNGQGRP
NTVALAVVKVDVAGEVLISAAEGNGPVNALDVALRKDIGKYQSYIDGLKLVDYRVRILNG
GTEAVTRVLVESEDENGARWTTIGVSSNVIDASFQALMDSLTYKLVKAGAPA
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgagccgcgaacgactctatctcttcgacaccacattgcgcgacggcgcccagacgcag
ggcgtcggcttttcgctgcacgacaagcgtatcattgcgcagatgctcgacgagcttggt
gtcgattacatcgagggcggctatccgggcgcgaacccggccgacagcgaattcttcagc
gagcggccgaagttttcgcacgccaagtttgtcgcgttcggcatggtgcgccggagcggg
cgttcggtgtcgaacgatcccggtcttgccgccgtgctggctgcaaagacggatgcgttc
tgtctggtcgcgaaggcgtcggcctatcaggtgcgcgtcgcgctcgaaaccaccaatgag
gagaacctcgccgcgatccgcgacagcatcagcgcggccgtcgccaagagcggcacggcg
atgctcgactgcgagcatttcttcgacggctacaaggaagacccggccttcgcgctggcc
tgtgccaaggcggcttatgaatccggtgcgcgctgggtggtgctgtgtgacaccaatggc
ggcacgttgcctcatgaggtcgaggcgatcgtcggcgaggtgacgaagcatatccccggc
agccatctcggcatccatgcccatgacgacaccgggcagggggtggcgaactcgctcgcc
gcggtgcgcgcgggcgtgcggcaaattcagggtacgctgaacggtctcggcgagcgttgc
ggcaacgccaatctctgctcgctgatcccgacactgaaattgaagaagccgttctgcgat
acgctcgaaatcaatgtcactgatgcgaagctagcgacgctgacgcaggtgtcgcgcgcg
ctcgacgaaatcctcaatcgtgcgccgaacaagcatgcgccctatgtcggcgagagtgcg
ttcgtcaccaagaccggcattcatgcttccgccgtgctgaaggacccgcacacctacgaa
catatcgtgccggagctggtcggcaatcaccgtcaggtgctggtatccgatcaggcaggc
cgctcgaacgtgctggccgcgctggagcgcgccggcatcgccttcgacaagagcgacccc
aaggtcacgcgcctcgttgaggagatgaaggagcgcgaggcgggcggttattcctacgag
tccgccgaggcctcgttcgagttgctggcgcggcgcacgctcggccatgtgccggattac
ttccgcgtcttgcagttcgacgtcaatgtcgagcagcgcaccaacggacagggccggccg
aacacggttgcgctcgcggtggtgaaggtcgacgtcgcgggcgaggtgctgatctcggcg
gcggaaggcaacggtccggtcaatgcgctcgacgtcgcgctacgcaaggatatcggcaag
tatcagagctatatcgacgggctcaagctcgtcgactatcgcgtccgtatcctcaacggc
ggcaccgaagcggtgacgcgcgtgctggtggagagcgaggacgagaacggtgcgcgctgg
accaccatcggcgtgtcgtcgaacgtcatcgacgcctcattccaggcgctgatggattcc
ctgacctacaagctggtgaaggccggcgccccggcgtga
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