KEGG   Oryctolagus cuniculus (rabbit): 100008645
Entry
100008645         CDS       T03373                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein
  KO
K13375  transforming growth factor beta-1
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04060  Cytokine-cytokine receptor interaction
ocu04068  FoxO signaling pathway
ocu04110  Cell cycle
ocu04148  Efferocytosis
ocu04218  Cellular senescence
ocu04350  TGF-beta signaling pathway
ocu04380  Osteoclast differentiation
ocu04390  Hippo signaling pathway
ocu04659  Th17 cell differentiation
ocu04672  Intestinal immune network for IgA production
ocu04926  Relaxin signaling pathway
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu05140  Leishmaniasis
ocu05142  Chagas disease
ocu05144  Malaria
ocu05145  Toxoplasmosis
ocu05146  Amoebiasis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05205  Proteoglycans in cancer
ocu05210  Colorectal cancer
ocu05211  Renal cell carcinoma
ocu05212  Pancreatic cancer
ocu05220  Chronic myeloid leukemia
ocu05225  Hepatocellular carcinoma
ocu05226  Gastric cancer
ocu05321  Inflammatory bowel disease
ocu05323  Rheumatoid arthritis
ocu05410  Hypertrophic cardiomyopathy
ocu05414  Dilated cardiomyopathy
ocu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    100008645 (TGFB1)
   04390 Hippo signaling pathway
    100008645 (TGFB1)
   04068 FoxO signaling pathway
    100008645 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100008645 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100008645 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100008645 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100008645 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100008645 (TGFB1)
   05205 Proteoglycans in cancer
    100008645 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100008645 (TGFB1)
   05212 Pancreatic cancer
    100008645 (TGFB1)
   05225 Hepatocellular carcinoma
    100008645 (TGFB1)
   05226 Gastric cancer
    100008645 (TGFB1)
   05220 Chronic myeloid leukemia
    100008645 (TGFB1)
   05211 Renal cell carcinoma
    100008645 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100008645 (TGFB1)
   05161 Hepatitis B
    100008645 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100008645 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100008645 (TGFB1)
   05144 Malaria
    100008645 (TGFB1)
   05145 Toxoplasmosis
    100008645 (TGFB1)
   05140 Leishmaniasis
    100008645 (TGFB1)
   05142 Chagas disease
    100008645 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100008645 (TGFB1)
   05321 Inflammatory bowel disease
    100008645 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100008645 (TGFB1)
   05414 Dilated cardiomyopathy
    100008645 (TGFB1)
   05415 Diabetic cardiomyopathy
    100008645 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100008645 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100008645 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ocu03110]
    100008645 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ocu04052]
    100008645 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:ocu00536]
    100008645 (TGFB1)
Chaperones and folding catalysts [BR:ocu03110]
 Intramolecular chaperones
  Others
   100008645 (TGFB1)
Cytokines and neuropeptides [BR:ocu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   100008645 (TGFB1)
Glycosaminoglycan binding proteins [BR:ocu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100008645 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 100008645
NCBI-ProteinID: XP_051692327
LinkDB
Position
Unknown
AA seq 387 aa
MLPSGMRLLLPLLWLLVLSPARPAVGTLSRNNTHMELLRQQHIQAVGALILAKLGLSSPP
SDDEVPTGPVPEDILALYNRTRDQVSGERAKQKPQPDSGFFGKEITSVPMLDSNHEIYQK
YKESRHSVYMFFNTSELRQAVPKPVLLSHAELRLQVLKLQQEQQVELYQKCSNDSWRYHR
RRKLTPSDTDEWLSFTVTWIVRQWLRGGEEIEGFRLSAHCSCDNKDNVLQVDINGISSGR
RGDLATIHSMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFR
KDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEP
LPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1164 nt   +upstreamnt  +downstreamnt
atgctgccctccgggatgcgactgctgctgcctctgctgtggctcctggtgctgtcaccc
gcccgcccagccgtgggaacgctcagccgcaacaacacccacatggagctgctcagacaa
cagcacatccaggccgtcggcgccctgatcctggccaagctggggctctccagcccccca
agtgatgatgaggtgccgacgggtccggtgcccgaggacatactcgccctgtacaacaga
acccgcgatcaggtgtccggggagagagctaaacagaagccccaacccgactcaggcttc
tttggcaaggagatcaccagtgtgccaatgctggacagcaaccacgaaatctaccaaaaa
tacaaagaaagtcggcacagcgtctatatgttcttcaacacgtcagagctccggcaagca
gtgcccaagccggtgttgctgtcccatgcagagctgcgcctgcaagtgctcaagttacag
caggagcagcaggtggagctgtaccagaaatgcagcaacgattcctggcgctaccacagg
aggcgtaagctgacacccagtgacacagatgagtggttgtcatttaccgtcacctggatt
gtgcggcagtggctgagaggtggagaggaaatagagggcttccgcctcagcgcccactgt
tcctgtgacaacaaagataatgtcctccaagtggacatcaacgggatcagttccggccgt
cgaggtgacctggccaccattcacagcatgaaccgacccttcctgctcctcatggccacc
cctctggaacgggctcaacatctacacagttcccggcaccgccgagccctggacaccaac
tactgcttcagctccacagagaagaactgctgtgtgcggcagctgtacattgacttccgc
aaggacctgggctggaagtggatccacgagcccaagggctaccacgccaacttctgcctg
ggaccctgcccctacatctggagcctggacacccagtacagcaaggtcctggccctgtac
aaccagcacaacccgggcgcgtcggcagcgccgtgctgtgtgccacaggcgctggagcca
ctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctgtccaacatgatc
gtgcgctcctgcaagtgcagctga

KEGG   Oryctolagus cuniculus (rabbit): 100009371
Entry
100009371         CDS       T03373                                 
Symbol
TGFB2
Name
(RefSeq) transforming growth factor beta-2 proprotein precursor
  KO
K13376  transforming growth factor beta-2
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04060  Cytokine-cytokine receptor interaction
ocu04068  FoxO signaling pathway
ocu04110  Cell cycle
ocu04218  Cellular senescence
ocu04350  TGF-beta signaling pathway
ocu04380  Osteoclast differentiation
ocu04390  Hippo signaling pathway
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu05140  Leishmaniasis
ocu05142  Chagas disease
ocu05144  Malaria
ocu05145  Toxoplasmosis
ocu05146  Amoebiasis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05205  Proteoglycans in cancer
ocu05206  MicroRNAs in cancer
ocu05210  Colorectal cancer
ocu05211  Renal cell carcinoma
ocu05212  Pancreatic cancer
ocu05220  Chronic myeloid leukemia
ocu05225  Hepatocellular carcinoma
ocu05226  Gastric cancer
ocu05321  Inflammatory bowel disease
ocu05323  Rheumatoid arthritis
ocu05410  Hypertrophic cardiomyopathy
ocu05414  Dilated cardiomyopathy
ocu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    100009371 (TGFB2)
   04390 Hippo signaling pathway
    100009371 (TGFB2)
   04068 FoxO signaling pathway
    100009371 (TGFB2)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100009371 (TGFB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100009371 (TGFB2)
   05206 MicroRNAs in cancer
    100009371 (TGFB2)
   05205 Proteoglycans in cancer
    100009371 (TGFB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100009371 (TGFB2)
   05212 Pancreatic cancer
    100009371 (TGFB2)
   05225 Hepatocellular carcinoma
    100009371 (TGFB2)
   05226 Gastric cancer
    100009371 (TGFB2)
   05220 Chronic myeloid leukemia
    100009371 (TGFB2)
   05211 Renal cell carcinoma
    100009371 (TGFB2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100009371 (TGFB2)
   05161 Hepatitis B
    100009371 (TGFB2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100009371 (TGFB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100009371 (TGFB2)
   05144 Malaria
    100009371 (TGFB2)
   05145 Toxoplasmosis
    100009371 (TGFB2)
   05140 Leishmaniasis
    100009371 (TGFB2)
   05142 Chagas disease
    100009371 (TGFB2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100009371 (TGFB2)
   05321 Inflammatory bowel disease
    100009371 (TGFB2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100009371 (TGFB2)
   05414 Dilated cardiomyopathy
    100009371 (TGFB2)
   05415 Diabetic cardiomyopathy
    100009371 (TGFB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100009371 (TGFB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ocu04052]
    100009371 (TGFB2)
   00536 Glycosaminoglycan binding proteins [BR:ocu00536]
    100009371 (TGFB2)
Cytokines and neuropeptides [BR:ocu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   100009371 (TGFB2)
Glycosaminoglycan binding proteins [BR:ocu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100009371 (TGFB2)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta DUF7594 Beta-prop_RIG_2nd RNase_H_2 SPEG_u2
Other DBs
NCBI-GeneID: 100009371
NCBI-ProteinID: NP_001076129
Ensembl: ENSOCUG00000005279
UniProt: Q6T7C3
LinkDB
Position
16:30643490..30735045
AA seq 442 aa
MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEP
EEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSYFPSETVCPV
VTTPSGSVGSLCARQSQVLCGYLDAIPPTFYRPYFRIVRFDVSTMEKNASNLVKAEFRVF
RLQNPKARVAEQHIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLH
HKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRK
KNSGKTPHLLLMLLPSYRLESQQSNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW
KWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILY
YIGKTPKIEQLSNMIVKSCKCS
NT seq 1329 nt   +upstreamnt  +downstreamnt
atgcactactgtgtgctgagcgcttttctgatcctgcatctggtcacggtggcgctcagc
ctgtctacctgcagcacactcgatatggaccagttcatgcgcaagaggatcgaggcgatc
cgcgggcagatcctaagcaagctgaagctcaccagccccccagaagactatcccgagccc
gaggaagtgcccccggaggtgatctccatctacaacagcaccagggacttgctccaggag
aaggcgagccggagggcggccgcctgcgagcgcgagaggagcgacgaggagtactacgcc
aaggaggtctacaagatagacatgccgtcctacttcccctccgaaactgtctgcccagtt
gttacaacaccctctggctcagtgggcagcttgtgcgccagacagtcccaggtgctctgt
gggtaccttgatgccatcccacccaccttctacagaccctacttcagaattgtccgattt
gatgtttcaacaatggagaagaatgcttccaatctggtgaaagcagagttcagagtcttt
cgtttgcagaacccaaaagccagagtggctgaacaacacatagaactgtatcagattctc
aaatccaaggatttaacatctccaacccagcgctacatcgacagcaaagtcgtgaaaaca
agagcagaaggcgaatggctctccttcgatgtaactgatgctgttcatgaatggcttcac
cataaagacaggaatctgggattcaaaataagtttacattgtccctgctgcacctttgta
ccttctaataattacatcatcccgaataaaagtgaagaactagaagcaagatttgcaggt
attgatggcacctctacatataccagtggggatcagaaaactataaagtccactaggaaa
aaaaacagtggaaagaccccacatctcctgctaatgttattgccctcctacagacttgag
tcacaacagtccaaccggcggaagaagcgtgcattggatgcagcctattgctttagaaat
gtgcaggataattgctgcctgcgtccactctacattgatttcaagagggatcttgggtgg
aaatggatacatgaacctaaagggtataatgccaacttctgtgctggggcatgcccgtat
ttatggagttcagacactcagcacagtagggtcctcagcttatataacaccataaatcca
gaagcatccgcttctccttgctgtgtgtcccaggatttagaacccctaacaattctctac
tatattggcaaaacacccaagattgaacagctttctaatatgatcgtaaagtcttgcaaa
tgcagctaa

KEGG   Oryctolagus cuniculus (rabbit): 100352301
Entry
100352301         CDS       T03373                                 
Name
(RefSeq) LOW QUALITY PROTEIN: transforming growth factor beta-1 proprotein
  KO
K13375  transforming growth factor beta-1
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04060  Cytokine-cytokine receptor interaction
ocu04068  FoxO signaling pathway
ocu04110  Cell cycle
ocu04148  Efferocytosis
ocu04218  Cellular senescence
ocu04350  TGF-beta signaling pathway
ocu04380  Osteoclast differentiation
ocu04390  Hippo signaling pathway
ocu04659  Th17 cell differentiation
ocu04672  Intestinal immune network for IgA production
ocu04926  Relaxin signaling pathway
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu05140  Leishmaniasis
ocu05142  Chagas disease
ocu05144  Malaria
ocu05145  Toxoplasmosis
ocu05146  Amoebiasis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05205  Proteoglycans in cancer
ocu05210  Colorectal cancer
ocu05211  Renal cell carcinoma
ocu05212  Pancreatic cancer
ocu05220  Chronic myeloid leukemia
ocu05225  Hepatocellular carcinoma
ocu05226  Gastric cancer
ocu05321  Inflammatory bowel disease
ocu05323  Rheumatoid arthritis
ocu05410  Hypertrophic cardiomyopathy
ocu05414  Dilated cardiomyopathy
ocu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    100352301
   04390 Hippo signaling pathway
    100352301
   04068 FoxO signaling pathway
    100352301
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100352301
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100352301
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100352301
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100352301
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100352301
   05205 Proteoglycans in cancer
    100352301
  09162 Cancer: specific types
   05210 Colorectal cancer
    100352301
   05212 Pancreatic cancer
    100352301
   05225 Hepatocellular carcinoma
    100352301
   05226 Gastric cancer
    100352301
   05220 Chronic myeloid leukemia
    100352301
   05211 Renal cell carcinoma
    100352301
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100352301
   05161 Hepatitis B
    100352301
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100352301
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100352301
   05144 Malaria
    100352301
   05145 Toxoplasmosis
    100352301
   05140 Leishmaniasis
    100352301
   05142 Chagas disease
    100352301
  09163 Immune disease
   05323 Rheumatoid arthritis
    100352301
   05321 Inflammatory bowel disease
    100352301
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100352301
   05414 Dilated cardiomyopathy
    100352301
   05415 Diabetic cardiomyopathy
    100352301
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100352301
   04933 AGE-RAGE signaling pathway in diabetic complications
    100352301
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ocu03110]
    100352301
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ocu04052]
    100352301
   00536 Glycosaminoglycan binding proteins [BR:ocu00536]
    100352301
Chaperones and folding catalysts [BR:ocu03110]
 Intramolecular chaperones
  Others
   100352301
Cytokines and neuropeptides [BR:ocu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   100352301
Glycosaminoglycan binding proteins [BR:ocu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100352301
SSDB
Motif
Pfam: TGFb_propeptide
Other DBs
NCBI-GeneID: 100352301
NCBI-ProteinID: XP_051692408
Ensembl: ENSOCUG00000030402
LinkDB
Position
Unknown
AA seq 273 aa
MAPSGMRLLLPLLWLSVLAPGRPAAEMPGRNATDLELQQRQHLEAFRALLLSKLKTPSPE
EEPTIPEPDDVDHSTREQNEEGLELLPRYFRKEVTRVPMLDSNHEIYKKYKDCGHSVYML
FNMSELRQAVPEPVLLSRAELRMQVLKLQQEQHVELYQKDSSDSWQYIKSRNLAPSDTDE
WLSIVVTRVVRTWLSRGEETEGFRLSTHCSCDSTDDVLQVDINGISSGRRGNHAAAHSMN
RPFLLLVATPLERALQLNGAWHHXALDTNYCFR
NT seq 822 nt   +upstreamnt  +downstreamnt
atggcgccctccgggatgcgactgctgctgccgctgctgtggctctcagtgttggcgccc
ggccgcccggccgcggaaatgcccggccgcaacgccaccgacctggagctgcagcaaagg
cagcacctggaggccttccgtgccctgctcctgtccaagctgaagacccccagcccggag
gaggaaccaaccattccggagcctgacgacgtggaccacagcacccgcgaacagaacgag
gagggccttgagctgttgccccgctacttccgcaaggaggtcacccgcgtgccaatgctg
gacagcaaccacgaaatttacaaaaaatacaaagattgcgggcacagcgtctatatgctc
ttcaacatgtcagagctccggcaagcagtgcctgagccggtgttgctgtccagggcagag
ctgcgcatgcaagtgctcaagttacagcaggagcagcacgtggagctgtaccagaaagac
agcagcgattcctggcaatacatcaagagccggaatctggcacccagtgacacagatgag
tggttgtccattgttgtcaccagagttgtgcggacgtggctgagccgtggagaggaaaca
gagggcttccgcctcagcacccactgctcctgtgacagcacagatgatgtcctccaagtg
gacatcaacgggatcagttccggccgccgaggtaaccatgccgccgctcatagcatgaac
cggcccttcctgctccttgtggctactcccctagagagggcactgcagctaaatggcgcc
tggcaccactgagccctggacaccaactactgcttcaggtga

KEGG   Oryctolagus cuniculus (rabbit): 100358982
Entry
100358982         CDS       T03373                                 
Name
(RefSeq) transforming growth factor beta-3 proprotein
  KO
K13377  transforming growth factor beta-3
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04060  Cytokine-cytokine receptor interaction
ocu04068  FoxO signaling pathway
ocu04110  Cell cycle
ocu04218  Cellular senescence
ocu04350  TGF-beta signaling pathway
ocu04390  Hippo signaling pathway
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu05140  Leishmaniasis
ocu05142  Chagas disease
ocu05144  Malaria
ocu05145  Toxoplasmosis
ocu05146  Amoebiasis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05210  Colorectal cancer
ocu05211  Renal cell carcinoma
ocu05212  Pancreatic cancer
ocu05220  Chronic myeloid leukemia
ocu05225  Hepatocellular carcinoma
ocu05226  Gastric cancer
ocu05321  Inflammatory bowel disease
ocu05323  Rheumatoid arthritis
ocu05410  Hypertrophic cardiomyopathy
ocu05414  Dilated cardiomyopathy
ocu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    100358982
   04390 Hippo signaling pathway
    100358982
   04068 FoxO signaling pathway
    100358982
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100358982
  09162 Cancer: specific types
   05210 Colorectal cancer
    100358982
   05212 Pancreatic cancer
    100358982
   05225 Hepatocellular carcinoma
    100358982
   05226 Gastric cancer
    100358982
   05220 Chronic myeloid leukemia
    100358982
   05211 Renal cell carcinoma
    100358982
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100358982
   05161 Hepatitis B
    100358982
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100358982
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100358982
   05144 Malaria
    100358982
   05145 Toxoplasmosis
    100358982
   05140 Leishmaniasis
    100358982
   05142 Chagas disease
    100358982
  09163 Immune disease
   05323 Rheumatoid arthritis
    100358982
   05321 Inflammatory bowel disease
    100358982
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100358982
   05414 Dilated cardiomyopathy
    100358982
   05415 Diabetic cardiomyopathy
    100358982
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100358982
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ocu04052]
    100358982
Cytokines and neuropeptides [BR:ocu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   100358982
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 100358982
NCBI-ProteinID: XP_002719681
Ensembl: ENSOCUG00000011415
UniProt: G1T192
LinkDB
Position
20:28840383..28865005
AA seq 458 aa
MHLLAKPQSLGSGEAAWFPSLLLHVCRGLLLSRPRRPPWPLSPARPMKMHLQRALVVLAL
LNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPSVMTHVPYQVLALYN
STRELLEELQAEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRF
NVSSVEKNGTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTR
GTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVD
NEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLGSPGQGAQRKKRALDTNYCFRNLEEN
CCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASA
SPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
NT seq 1377 nt   +upstreamnt  +downstreamnt
atgcaccttcttgccaagcctcagtctttgggatctggggaggccgcctggtttccctcc
ctccttctgcacgtctgccggggtctcctcctctccaggccgcgccgccccccctggcct
ctctccccggctcgccccatgaagatgcacttgcaaagggctctggtggtcctggccctg
ctgaactttgccacggtcagcctctctctgtccacttgcaccaccttggacttcggccac
atcaaaaagaagagagtggaagccattaggggacagatcttgagcaagctcaggctcacc
agcccccctgagccgtcggtgatgacccacgtcccctaccaggtcctggccctttataac
agcactcgggagctgctggaggagctgcaggcagagagggaggaaggctgcactcaggaa
aacaccgagtcggaatactatgccaaagagatccataaattcgacatgatccagggactg
gcggagcacaacgagctggccgtgtgtcccaaaggaatcacctccaaggttttccgcttc
aacgtgtcctcagtggagaagaacggaaccaacctgttccgggcagaattccgggtcttg
cgtgtgcccaaccccagctccaagcgcaacgagcagaggattgagctcttccagatcctc
cggccggatgagcacatcgccaagcagcgctacatcggcggcaagaatctgcccacgcgg
ggcaccgccgagtggctgtcctttgacgtcacggacaccgtgcgcgagtggctgctgcga
agagagtccaacttgggtctggagatcagcattcattgtccgtgccacacctttcagccc
aacggagacatcctggaaaacattcacgaggtgatggaaataaaattcaaaggcgtggac
aacgaggacgaccacggccgtggcgatctagggcggctcaagaagcagaaggatcaccac
aaccctcacctcatcctcatgatgattccaccgcaccggctcggcagcccgggccagggc
gcacagaggaagaagcgggccctggacaccaattactgcttccgcaacttggaggagaac
tgctgtgtgcgtccactctacattgacttccgccaggatctgggctggaaatgggtccac
gaacccaagggctactacgccaacttctgctctggcccgtgcccatacctccgcagtgca
gacaccacccacagcacggtgctgggactctacaacaccctgaacccggaagcctcggcc
tcgccctgctgcgtccctcaggacttggagcccctgaccatcctgtactacgtcgggagg
acccccaaggtggagcagctctccaacatggtggtgaagtcctgcaagtgcagctga

KEGG   Oryctolagus cuniculus (rabbit): 103345448
Entry
103345448         CDS       T03373                                 
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X9
  KO
K13375  transforming growth factor beta-1
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04060  Cytokine-cytokine receptor interaction
ocu04068  FoxO signaling pathway
ocu04110  Cell cycle
ocu04148  Efferocytosis
ocu04218  Cellular senescence
ocu04350  TGF-beta signaling pathway
ocu04380  Osteoclast differentiation
ocu04390  Hippo signaling pathway
ocu04659  Th17 cell differentiation
ocu04672  Intestinal immune network for IgA production
ocu04926  Relaxin signaling pathway
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu05140  Leishmaniasis
ocu05142  Chagas disease
ocu05144  Malaria
ocu05145  Toxoplasmosis
ocu05146  Amoebiasis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05205  Proteoglycans in cancer
ocu05210  Colorectal cancer
ocu05211  Renal cell carcinoma
ocu05212  Pancreatic cancer
ocu05220  Chronic myeloid leukemia
ocu05225  Hepatocellular carcinoma
ocu05226  Gastric cancer
ocu05321  Inflammatory bowel disease
ocu05323  Rheumatoid arthritis
ocu05410  Hypertrophic cardiomyopathy
ocu05414  Dilated cardiomyopathy
ocu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    103345448
   04390 Hippo signaling pathway
    103345448
   04068 FoxO signaling pathway
    103345448
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103345448
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    103345448
  09152 Endocrine system
   04926 Relaxin signaling pathway
    103345448
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103345448
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103345448
   05205 Proteoglycans in cancer
    103345448
  09162 Cancer: specific types
   05210 Colorectal cancer
    103345448
   05212 Pancreatic cancer
    103345448
   05225 Hepatocellular carcinoma
    103345448
   05226 Gastric cancer
    103345448
   05220 Chronic myeloid leukemia
    103345448
   05211 Renal cell carcinoma
    103345448
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103345448
   05161 Hepatitis B
    103345448
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    103345448
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103345448
   05144 Malaria
    103345448
   05145 Toxoplasmosis
    103345448
   05140 Leishmaniasis
    103345448
   05142 Chagas disease
    103345448
  09163 Immune disease
   05323 Rheumatoid arthritis
    103345448
   05321 Inflammatory bowel disease
    103345448
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    103345448
   05414 Dilated cardiomyopathy
    103345448
   05415 Diabetic cardiomyopathy
    103345448
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    103345448
   04933 AGE-RAGE signaling pathway in diabetic complications
    103345448
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ocu03110]
    103345448
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ocu04052]
    103345448
   00536 Glycosaminoglycan binding proteins [BR:ocu00536]
    103345448
Chaperones and folding catalysts [BR:ocu03110]
 Intramolecular chaperones
  Others
   103345448
Cytokines and neuropeptides [BR:ocu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   103345448
Glycosaminoglycan binding proteins [BR:ocu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   103345448
SSDB
Motif
Pfam: TGFb_propeptide
Other DBs
NCBI-GeneID: 103345448
NCBI-ProteinID: XP_017193743
LinkDB
Position
Unknown
AA seq 267 aa
MLPCGMRLLLPLLWLLVLSPARPAAGMPSRNTTEVELLRQQHIEAVHSTIQSPPSEEEVP
EDVLTLNSRTHDQGSGESNKQEPKPKLNFSAGKELTGVPMLESDHESYQKFNVSRHSVYM
LFNMSELREVMPEPWLLSGAELHLQVLKLQQEQHMELYQKDSNDSWRYLSNRLLAPSNTA
EWLSFDVTGVVQQWLSHGGEDEEIEGFRLSARRSSDNTDDVLHVKINGISSSGQGDNANV
QKSYRPYLLLIVNPLDRIVPPDPSELI
NT seq 804 nt   +upstreamnt  +downstreamnt
atgctgccctgcgggatgcgactgctgctgcctctgctgtggctcctggtgttgtcaccc
gcccgcccagccgcaggaatgcccagccgcaacaccaccgaggtggagctgctcagacaa
cagcacatcgaggccgttcactccacgatccagagccccccgagcgaggaggaagtgccc
gaagacgtgctcaccctgaacagcagaacccatgaccaggggtctggagagagcaataag
caagagcccaaacccaagttaaacttctctgcaggcaaggagctcaccggcgtgccaatg
ctggagagcgaccacgaaagctatcaaaaattcaacgtaagccggcacagcgtctatatg
ctcttcaacatgtcagagctccgggaagtaatgccagagccatggttgctgtctggggca
gagctgcacctgcaagtgctcaagttacagcaggagcagcacatggagctgtaccagaaa
gacagcaatgattcctggcgctacctcagcaaccggctgctggccccaagcaacacagca
gagtggttgtccttcgatgtcactggagttgtgcagcagtggctgagccacggaggtgaa
gatgaggaaatagagggcttccgcctcagcgcccggaggtccagtgacaacacagatgat
gtcctccatgtgaaaatcaatgggatcagttccagtggccagggtgacaatgccaacgtt
cagaaatcctaccggccctatctgctcctcatcgtcaacccactggaccgcattgtgccc
ccagacccctcggagctgatctga

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