Oryctolagus cuniculus (rabbit): 100009089 Help Entry 100009089         CDS       T03373                                  Name (RefSeq) calpain-1 catalytic subunit   KO K01367   calpain-1 [EC:3.4.22.52] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu04141   Protein processing in endoplasmic reticulum ocu04210   Apoptosis ocu04217   Necroptosis ocu04218   Cellular senescence ocu05010   Alzheimer disease ocu05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:ocu00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     100009089  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100009089    05022 Pathways of neurodegeneration - multiple diseases     100009089  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ocu01002]     100009089 Enzymes [BR:ocu01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.52  calpain-1      100009089 Peptidases and inhibitors [BR:ocu01002]  Cysteine peptidases   Family C2: calpain family    100009089 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C2 Calpain_III EF-hand_1 EF-hand_6 EF-hand_7 EF-hand_8 CAPN13-like_C_EFh EF-hand_5 Motif Other DBs NCBI-GeneID:  100009089 NCBI-ProteinID:  XP_051687381 Ensembl:  ENSOCUG00000003122 LinkDB All DBs Position Unknown AA seq 714 aa AA seqDB search MAEEIITPVYCTGVSAQVQKQRAKELGLGRHENAIKYLGQDYEQLRMHCLQSGALFRDEA FPPVPQSLGYKELGPNSSKTYGIKWKRPTELLSNPRFIVDGATRTDICQGALGDCWLLAA IASLTLNDTLLHRVVPHGQSFQDGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHS AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILK ALERGSLLGCSIDISSVLDMEAVTFKKLVKGHAYSVTGAKQVNYQGQMVSLIRMRNPWGE VEWTGAWSDSSPEWNYVDPYEREQLRIKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS RTIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEEVDDEDDYGSRESGCSFV LALMQKHRRRERRFGRDMETIGFAVYEVPRELVGQPALHLKRDFFLANASRARSEQFINL REVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKRAGTQELDDQIQANLPDEQVLSA EEIDENFKALFRQLAGEDLEISVRELQTILNRIISKHKDLRTKGFSMESCRSMVNLMDRD GNGKLGLVEFNILWNRIRNYLAIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELII TRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA NT seq 2145 nt NT seq  +upstreamnt  +downstreamnt atggccgaagagatcatcacgccggtgtactgcaccggggtgtcggcccaagtgcagaag cagcgggccaaggagctgggcctgggccggcatgaaaacgccatcaagtacctgggccag gattacgagcagctacggatgcactgcctgcagagcggggccctcttccgcgacgaggcc ttccccccggtaccccagagcctgggctacaaggagctggggcccaactcctccaagacc tacggcatcaagtggaagcgccccacggagctgctgtcaaacccgcggttcatcgtggac ggagccacccgcacagacatctgccagggagcgctgggggactgctggctgctggctgcc atcgcctccctcaccctcaatgacaccctcctgcaccgagtggtcccacacggccagagc ttccaggacggctatgccggcatcttccacttccagctgtggcagttcggggagtgggtg gatgtggtcgtggacgacctgctgcccaccaaggacgggaagctggtgttcgtgcactcc gcccagggcaacgagttctggagcgccctgctggagaaggcctacgccaaggtgaacggc agctacgaggccctgtccgggggcagcacgtccgagggcttcgaggacttcacgggcggc gtcaccgagtggtacgagctgcgcaaggcccccagtgacctctaccagatcatcctcaag gcactggagcggggctcgctgctgggctgctccatcgacatctccagcgttctcgacatg gaggctgtcaccttcaagaagctggtaaagggccacgcctactctgtgaccggcgccaag caggtgaactaccagggccagatggtgagcctgatccggatgcggaacccttggggcgag gtggagtggacaggagcctggagtgacagctccccggagtggaactacgtggacccgtac gagcgggagcagctccggatcaagatggaggacggcgagttctggatgtccttccgcgac ttcatgcgggagttcacccgcctggagatctgtaacctgacgcccgacgcgctcaagagc cggaccatccgcaagtggaacaccacactctacgagggcacctggcggaggggcagcacc gcgggcggctgccgcaactacccagccaccttctgggtgaacccccagttcaagatccgg ctggaggaggtggatgacgaagacgactatggcagccgcgagtcgggctgcagcttcgtg ctggccctgatgcagaaacaccgccggcgcgagcgccgcttcggccgcgacatggagacc atcggcttcgcggtgtacgaggtccctcgggagctggtgggccagcccgccctgcacctg aagcgtgacttcttcctggccaacgcgtctcgggcgcgctcggagcagttcatcaacctg cgagaggtcagcacccgcttccgcctgccgcccggggagtacgtggtggtgccctcgacc ttcgagcccaacaaggagggcgacttcgtgctgcgcttcttctcggagaagagggcaggg acccaggagctggacgaccagattcaggccaatctccctgacgagcaagtgctctccgca gaagagatcgatgaaaacttcaaggctctcttcagacaactggcaggggaggacctggag atcagcgtcagggagctgcagaccatcctcaacaggatcatcagcaaacacaaagacctg cgtaccaagggcttcagcatggagtcgtgccgcagcatggtgaacctcatggaccgtgat ggtaacggcaagctgggcctggtggagttcaacatcctgtggaaccgcatccggaattac ctggccatcttccggaagtttgacctggacaagtcgggcagcatgagcgcctatgagatg cgcatggccatcgagtctgcaggcttcaagctcaacaagaagttgtatgagctcatcatc acccgctactcggagcccgacctggccgtggacttcgacaactttgtgtgctgcctggtg cgactggagaccatgttccgatttttcaaaactctggacaccgatctggatggagtcgtg acctttgacctattcaagtggctacagctgaccatgttcgcctga

Oryctolagus cuniculus (rabbit): 100009092 Help Entry 100009092         CDS       T03373                                  Symbol CAPN2 Name (RefSeq) calpain-2 catalytic subunit   KO K03853   calpain-2 [EC:3.4.22.53] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu04141   Protein processing in endoplasmic reticulum ocu04210   Apoptosis ocu04217   Necroptosis ocu04218   Cellular senescence ocu04510   Focal adhesion ocu05010   Alzheimer disease ocu05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:ocu00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     100009092 (CAPN2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100009092 (CAPN2)    05022 Pathways of neurodegeneration - multiple diseases     100009092 (CAPN2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ocu01002]     100009092 (CAPN2) Enzymes [BR:ocu01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.53  calpain-2      100009092 (CAPN2) Peptidases and inhibitors [BR:ocu01002]  Cysteine peptidases   Family C2: calpain family    100009092 (CAPN2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C2 Calpain_III EF-hand_6 EF-hand_1 EF-hand_8 EF-hand_7 Motif Other DBs NCBI-GeneID:  100009092 NCBI-ProteinID:  NP_001182651 Ensembl:  ENSOCUG00000004612 LinkDB All DBs Position 16:35938806..35985528 Genome browser AA seq 700 aa AA seqDB search MAGIAARLARDREAAEGLGSHERAVKYLNQDYEALRDACLEAGTLFQDPSFPAQPSSLGF KELGPYSSKTRGIEWKRPTELSPEPQFIVGGATRTDICQGALGDCWLLAAIASLTLNEEV LARVVPLDQSFQENYAGIFRFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKAPPDLFRIIQKALQKGSLLGC SIDITSAADSEAITLQKLVKGHAYSVTGAEEVESAGSLQKLIRIRNPWGEVEWTGRWNDN CPNWNTVDPEVRERLAERHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK MDGNWRRGSTAGGCRNYPNTFWMNPQYVIKLEEEDEDQEDGESGCTFLVGLIQKHRRRQR KMGEDMHTIGFGIYEVPEELRGQTNIHLGKNFFLTTRARERSDTFINLREVLNRFKLPPG EYILVPSTFEPNKNGDFCVRVFSEKKADYQAVDDEIEADLEEADVSEDDIDDGFRRLFAQ LAGEDAEISAFELQNILRRVLAKRQDIKTDGFSIETCKIMVDMLDSDGTGKLGLKEFYVL WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHEVIVARFADDQLIIDFD NFVRCLVRLETLFKIFKQLDPDNTGMIQLDLISWLCFSVL NT seq 2103 nt NT seq  +upstreamnt  +downstreamnt atggcgggcatcgcagccaggctggccagggaccgggaggcggccgaagggctgggctcg cacgagagggccgtcaagtacctgaaccaggactacgaagcgctgcgggacgcgtgcctg gaggccgggacgctcttccaggacccctccttcccggcccagccctcgtcgctgggcttc aaggagctggggccctactccagcaagactcggggcatcgagtggaagcggcccacggag ctgagccctgagccccagttcatcgttggaggagccacccgcacagacatctgccaggga gccctgggtgactgctggctgctggcggccatcgcctcgctgaccctcaatgaggaggtc ctggcccgagtcgtgcccctggaccagagcttccaggagaactacgcaggcatcttccgc ttccagttctggcagtatggcgagtgggtggaggtggtggtggacgaccggctgcccacc aaggacggggagctgctgttcgtgcactcggcagaggggagcgagttctggagcgccctg ctggagaaggcctacgccaagatcaacggatgctacgaggcgctctcggggggcgccacc accgagggcttcgaggacttcacggggggcatcgccgagtggtatgagctgaagaaggcc cctcccgacctgttcaggatcatccagaaggctctgcagaaaggctctctcctgggctgc tccatcgatatcaccagcgccgccgactcggaggccatcacgctgcagaagctggtgaag ggccacgcgtactcggtcaccggagccgaggaggttgaaagtgctgggagcctgcagaag ctgatccgcatccgcaacccctggggagaagtggagtggaccgggaggtggaacgacaac tgcccaaactggaacactgtggacccggaggtgagggagaggctggccgaacggcatgaa gacggcgagttctggatgtccttcagcgacttcctgaggcactactcccgcctggagatc tgcaacctgacgcccgacaccctcaccagcgacacctacaagaagtggaaactcaccaag atggacggcaactggcggcggggctccaccgcgggaggctgcaggaactacccgaacact ttctggatgaacccccagtacgtgatcaagctggaggaggaggacgaggaccaggaggac ggcgagagcggctgcaccttcctggtgggcctcatccagaagcaccggcggcgccagagg aagatgggcgaggacatgcacaccatcggcttcggcatctacgaggttccagaagagcta cgggggcagaccaacatccacctcggcaaaaacttcttcctgaccacgcgggcgagagag cggtcggacaccttcatcaacctgcgcgaggtgctcaaccgcttcaagctgccgccgggg gagtacatcctggtgccctccaccttcgagcccaacaagaatggcgacttctgcgtccgt gtcttttccgagaagaaggccgactaccaagctgtcgatgatgaaatcgaggccgacctg gaagaggccgacgtcagcgaggatgacattgacgatggattccggaggctgtttgcccag ctggcaggggaggatgcagagatttcggcctttgagttgcagaacatcctgagacgagtc ctggcgaagcgacaagatatcaagacagatggcttcagcattgagacctgcaaaatcatg gtggacatgctcgactcagatgggactggcaagctggggctgaaggagttctatgttctc tggacaaagattcagaaataccagaaaatttaccgggaaatcgacgtggacaggtctggc accatgaattcctatgagatgcggaaagccctagaagaagcaggcttcaagctgccctgc caactgcacgaggtcatcgtcgctcgcttcgccgacgaccagctcatcatcgacttcgac aacttcgttcgctgcctggtgcgactggagacgctcttcaagatatttaagcagctggac cccgacaacactggcatgatacagctcgacctcatctcttggctctgcttctccgttctc tga

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