Oryctolagus cuniculus (rabbit): 100009201 Help Entry 100009201         CDS       T03373                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04020   Calcium signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04727   GABAergic synapse ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04922   Glucagon signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05032   Morphine addiction ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100009201 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100009201 (ADCY2)    04371 Apelin signaling pathway     100009201 (ADCY2)    04020 Calcium signaling pathway     100009201 (ADCY2)    04072 Phospholipase D signaling pathway     100009201 (ADCY2)    04024 cAMP signaling pathway     100009201 (ADCY2)    04022 cGMP-PKG signaling pathway     100009201 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100009201 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     100009201 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100009201 (ADCY2)    04062 Chemokine signaling pathway     100009201 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     100009201 (ADCY2)    04922 Glucagon signaling pathway     100009201 (ADCY2)    04923 Regulation of lipolysis in adipocytes     100009201 (ADCY2)    04912 GnRH signaling pathway     100009201 (ADCY2)    04913 Ovarian steroidogenesis     100009201 (ADCY2)    04915 Estrogen signaling pathway     100009201 (ADCY2)    04914 Progesterone-mediated oocyte maturation     100009201 (ADCY2)    04921 Oxytocin signaling pathway     100009201 (ADCY2)    04926 Relaxin signaling pathway     100009201 (ADCY2)    04935 Growth hormone synthesis, secretion and action     100009201 (ADCY2)    04918 Thyroid hormone synthesis     100009201 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     100009201 (ADCY2)    04916 Melanogenesis     100009201 (ADCY2)    04925 Aldosterone synthesis and secretion     100009201 (ADCY2)    04927 Cortisol synthesis and secretion     100009201 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100009201 (ADCY2)    04270 Vascular smooth muscle contraction     100009201 (ADCY2)   09154 Digestive system    04970 Salivary secretion     100009201 (ADCY2)    04971 Gastric acid secretion     100009201 (ADCY2)    04972 Pancreatic secretion     100009201 (ADCY2)    04976 Bile secretion     100009201 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     100009201 (ADCY2)    04727 GABAergic synapse     100009201 (ADCY2)    04725 Cholinergic synapse     100009201 (ADCY2)    04723 Retrograde endocannabinoid signaling     100009201 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100009201 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     100009201 (ADCY2)    04213 Longevity regulating pathway - multiple species     100009201 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     100009201 (ADCY2)    04714 Thermogenesis     100009201 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100009201 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     100009201 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100009201 (ADCY2)    05163 Human cytomegalovirus infection     100009201 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     100009201 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100009201 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100009201 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100009201 (ADCY2) Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100009201 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  100009201 NCBI-ProteinID:  XP_008247060 Ensembl:  ENSOCUG00000008557 LinkDB All DBs Position Un Genome browser AA seq 1101 aa AA seqDB search MGAGSRWTAAAAPAPAGAPGATAAGTAAAAAGGGEGLQRSRDWLYESYYCMSQQHPLIVF LLLIVMAACLALLAVFFALSLEVEDHVAFLITVPTALAIFFAIFILVCVEAVFKKLLRLF SLVIWICLVAMGFLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSH TIVLSICLSASPGAKEHLVWQILANVIIFICGNLAGAYHKQLMELALQQTYRDTCNCIKS RIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGHMENTNNFHNLYVKRHTNV SILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPI SLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHD VTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGE RRSPHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPM GQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEK EYRATALPAFKYYVTCACLIFFCIFLVQILVLPKTSILGISFGAAFLSLAFILFVCFAGQ LLQCSKKASASLMWLLKSSGIIANRPWPRISLTVITTAIILTMAVFNMFFLSDSEEAILP TANTSNTSFPASSNQAAILRAQSLFFLPYFIYCCILGLISCSVFLRINYELKMLIMMVAL VAYNILLLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLSIFFVTLLVLGRQNEYYCRL DFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMF ASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATG LSAVPSQEHAQEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGV IGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGD LKTYFVNTEMSRSLSQSNVAS NT seq 3306 nt NT seq  +upstreamnt  +downstreamnt atgggggctgggagccgatggacagcggcggcggccccagccccggcgggggcccccggg gcgacggcggcggggacggcggcggcggcggcgggcggcggcgaggggctgcagcggtcc cgggactggctgtacgagtcctactactgcatgagccagcagcacccgctcatcgtcttc ctgctgctcatcgtcatggcggcctgcctcgccctgctcgccgtcttcttcgccctgtct ttggaagtggaggaccatgtggcatttttaatcacagtccccaccgccctggcgattttc tttgccatattcatcctggtgtgcgttgaggccgtgtttaagaagctgctccgcctcttc tccttggtgatatggatctgcctggtagccatggggttcctgttcatgtgctttggaggc actgtctctccctgggaccaggtgtctttcttcctcttcatcatcttcgtggtgtacacc atgctgcccttcaacatgcgagacgccatcatcgccagcgtcctcacctcctcttcccac accatcgtgctgagcatctgcctgtctgcatcgccaggggccaaggagcatctggtctgg cagatcctggccaacgtgatcatcttcatctgcgggaacctggcaggagcctaccacaag cagctcatggagctggcgctgcagcagacctaccgagacacctgcaactgcatcaagtcc cggatcaagctggaattcgagaagcgtcagcaggagcggctgctgctctccttgctgcca gctcacatcgccatggaaatgaaggcggagatcatccagagactgcaaggccccaaggcg ggccacatggaaaacacgaacaacttccacaacctgtacgtgaagcggcacaccaacgtc agcatcttatacgccgacatcgtgggctttacccggctggcgagtgactgctccccagga gaactggtccatatgctgaatgagctctttggaaagtttgatcagattgcaaaggagaat gaatgcatgagaattaaaatcttaggagactgctattactgtgtgtccggactccccata tctctccccaaccatgccaagaattgtgtgaaaatgggactggatatgtgtgaagccata aagaaagtcagggatgccactggagttgacatcaacatgcgtgtgggagtgcattctggg aacgtgctgtgtggcgtgattggtctgcagaaatggcagtacgacgtgtggtcacatgat gtcaccttggccaatcacatggaggctggcggagtccctggacgtgtccacatttcttca gtcaccctggagcacctgaatggcgcctacaaggtggaggagggagatggtgacatcagg gacccatatttgaaacagcacctggtgaaaacctacttcgtcatcaacccaaagggagag cggcggagtccccatctcttcagacctcgccacaccctcgatggagccaagatgagggcg tctgtgcgcatgacccggtacctggagtcctggggtgcagccaagccctttgcgcacctg catcacagagacagcatgaccaccgagaatggcaagatcagcaccacggatgtgccaatg ggtcagcataattttcagaatcgcaccttaagaaccaagtcacaaaagaaaaggtttgaa gaagaattgaatgaaaggatgattcaagcaattgatggaatcaatgcacaaaagcaatgg ctcaaatctgaagatatccaaagaatctcactgcttttctataacaaaatactcgaaaaa gaataccgagccactgcactgccggcattcaagtactatgtgacttgtgcgtgtctcata ttcttctgcatctttctcgtgcagattctcgtattgccaaaaacgtccatccttgggatt tcctttggagctgcatttctctcgcttgcctttatccttttcgtctgctttgctggacag cttttgcaatgcagcaaaaaagcctctgcgtctctcatgtggcttttgaagtcctcaggc atcattgccaaccgcccctggccgcgcatctccctcacggtcatcaccacggccatcatc ttgaccatggctgtgttcaacatgttcttcctgagtgactcagaggaagcaatccttcca actgccaatacttcaaacacaagtttccccgcctcaagcaatcaggcagcgattctgcgc gcacaaagcttatttttcctcccgtatttcatctactgctgcattctgggcttgatctcc tgttcggttttcctgcggataaattatgagttgaaaatgttgatcatgatggtggccttg gtggcctacaacatcctcctactccacacccacgcccacgtcctggacgactacagccag gtcttgtttgagaggccaggcatttggaaagacctgaagaccatgggctcagtgtctctc tctatatttttcgtcactctgctggtcctgggaagacagaatgaatattactgtaggttg gacttcctgtggaagaacaagttcaaaaaagagcgggaggagatagaaaccatggagaac ctgaaccgtgtgctgctggagaacgtgcttccggcccacgtggctgagcacttcctggcc cgcagcctgaagaacgaggagttgtaccaccagtcctacgactgtgtctgcgtcatgttt gcctccatcccggatttcaaagaattctacaccgagtcggatgtgaacaaggaaggcctg gaatgcctgcggctcctgaacgagatcatcgctgactttgatgatctgctgtccaagcca aaattcagtggcgttgaaaagatcaagaccatcggcagcacgtacatggcagcgacgggt ctgagtgccgtgcccagccaggagcacgcccaggagcccgagcggcagtacatgcacatt ggcacgatggtggagtttgcttttgccctggtggccaaactggatgccatcaacaagcac tccttcaacgacttcaagctgcgagtgggcattaaccacggacctgtgatcgctggtgtc atcggagcccagaagccccagtacgacatctggggcaacacagtcaacgtggccagcagg atggacagcaccggagtcctggacaagatacaggtgaccgaggagaccagcctcatcctg cagacgcttgggtacacgtgcacctgccgagggatcatcaacgtgaagggcaagggggac ctgaagacgtactttgtcaacacagaaatgtcaaggtccctgtcccagagcaacgtggcc tcctga

Oryctolagus cuniculus (rabbit): 100009315 Help Entry 100009315         CDS       T03373                                  Symbol ADCY5, RUT Name (RefSeq) adenylate cyclase 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04726   Serotonergic synapse ocu04727   GABAergic synapse ocu04728   Dopaminergic synapse ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04924   Renin secretion ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05012   Parkinson disease ocu05030   Cocaine addiction ocu05031   Amphetamine addiction ocu05032   Morphine addiction ocu05034   Alcoholism ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100009315 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100009315 (ADCY5)    04371 Apelin signaling pathway     100009315 (ADCY5)    04072 Phospholipase D signaling pathway     100009315 (ADCY5)    04024 cAMP signaling pathway     100009315 (ADCY5)    04022 cGMP-PKG signaling pathway     100009315 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100009315 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     100009315 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100009315 (ADCY5)    04062 Chemokine signaling pathway     100009315 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     100009315 (ADCY5)    04923 Regulation of lipolysis in adipocytes     100009315 (ADCY5)    04912 GnRH signaling pathway     100009315 (ADCY5)    04913 Ovarian steroidogenesis     100009315 (ADCY5)    04915 Estrogen signaling pathway     100009315 (ADCY5)    04914 Progesterone-mediated oocyte maturation     100009315 (ADCY5)    04921 Oxytocin signaling pathway     100009315 (ADCY5)    04926 Relaxin signaling pathway     100009315 (ADCY5)    04935 Growth hormone synthesis, secretion and action     100009315 (ADCY5)    04918 Thyroid hormone synthesis     100009315 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     100009315 (ADCY5)    04916 Melanogenesis     100009315 (ADCY5)    04924 Renin secretion     100009315 (ADCY5)    04925 Aldosterone synthesis and secretion     100009315 (ADCY5)    04927 Cortisol synthesis and secretion     100009315 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100009315 (ADCY5)    04270 Vascular smooth muscle contraction     100009315 (ADCY5)   09154 Digestive system    04970 Salivary secretion     100009315 (ADCY5)    04971 Gastric acid secretion     100009315 (ADCY5)    04972 Pancreatic secretion     100009315 (ADCY5)    04976 Bile secretion     100009315 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     100009315 (ADCY5)    04727 GABAergic synapse     100009315 (ADCY5)    04725 Cholinergic synapse     100009315 (ADCY5)    04728 Dopaminergic synapse     100009315 (ADCY5)    04726 Serotonergic synapse     100009315 (ADCY5)    04723 Retrograde endocannabinoid signaling     100009315 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100009315 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     100009315 (ADCY5)    04213 Longevity regulating pathway - multiple species     100009315 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     100009315 (ADCY5)    04714 Thermogenesis     100009315 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100009315 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     100009315 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100009315 (ADCY5)    05163 Human cytomegalovirus infection     100009315 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     100009315 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     100009315 (ADCY5)    05031 Amphetamine addiction     100009315 (ADCY5)    05032 Morphine addiction     100009315 (ADCY5)    05034 Alcoholism     100009315 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100009315 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100009315 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100009315 (ADCY5) Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100009315 (ADCY5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom HNOBA TBK1_ULD DUF2339 GBR2_CC Motif Other DBs NCBI-GeneID:  100009315 NCBI-ProteinID:  NP_001076097 Ensembl:  ENSOCUG00000015141 UniProt:  P40144 LinkDB All DBs Position 14:95675819..95837536 Genome browser AA seq 1264 aa AA seqDB search MSGSKGVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA VTPQQQQQQQRLASRWRGDDDDEPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRR QRRGAAGGGSTRAPPAGGGCGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRAVDELEA GAVEGGEGAEDGGSSADSSNGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRL NQSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDH MGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLL STLHLAIALRTNAQDRFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQA RLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEG FTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCC VEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEA GGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIA KMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESTNPEDEVD EFLGRAIDARSIDRLRSEHVRRFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICC VQITIVPHSMFMLSFYLACFLLLTLVVFVSMIYSCVKLFPRPLQSLSRKIVRSKMNSTLV GVFTITLVFLSAFVNMFMCNSKDLLDCLAAEHNISVIHVNACHVVESAFNYSLGNEQGFC GNSRPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELTYVLIVEVPRVTLFDN ADLLVTANAIDISSNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFL WKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASI ANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLND STYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYD IWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGG PPLS NT seq 3795 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaggcgtgagccctccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggccccgaacatcgctcagcttggggggaggccgactctcgtgccaat ggctacccccacgcccccgggggttctgctcgcggctccaccaagaaaccagggggggcg gtgaccccacagcagcagcaacagcagcagcgcctggccagccgctggcgcggcgacgac gacgacgagccgccgttgagcggcgacgatcccttggccgggggcttcggctttagcttc cgctccaagtccgcctggcaggagcgcggcggcgacgactgcggtcgcggcagccggcgg cagcggcggggcgcggccggcgggggcagcactcgggcgccccctgcgggcggcggctgc ggcggcggctcggcggcagcggccgctgcggcgggcgggacggaggtgcgcccccgttcg gtggagctgggcctggaggagcggcgaggcaagggccgcgcggtggacgagctggaggcc ggtgccgtcgagggcggtgaaggggcagaggatggcggcagctccgcggactccagcaac gggcccggcgcggtgctgtcgctgggcgcctgctgcctggcgttgctgcagattttccgc tccaagaagttcccgtccgacaagctggagcggctgtaccagcgctacttcttccgcctg aaccagagcagcctcaccatgctcatggccgtgctggtgctcgtgtgcctcgtcatgctg gccttccacgcggcgcgccccccactccagctgccctacctggcggtgctggcggccgcc gtgggcgtgatcctcgtcatggccgtgctgtgcaaccgcgcagccttccaccaggaccac atgggcctggcctgctatgcgctcatcgccgtggtgctggctgtccaggtggtgggcctg ctgctgccccagccgcgcagtgcctccgagggcatctggtggaccgtgttcttcatctac accatctacacgctgctgcctgtgcgcatgcgggctgcggtcctcagcggggtgctcctg tccaccctgcacctggccatcgccctgcgcaccaacgcccaggaccggttcctgctcaag cagctggtctccaacgtcctcatcttctcctgcaccaacattgtgggcgtctgcacccac tatccggccgaggtctcccagaggcaggccttccaggagacccgcgagtgcatccaggca cggctccactcgcagcgggagaaccagcaacaggagcggctcctgctgtccgtccttccc cgccacgttgccatggagatgaaagcagacatcaatgccaagcaggaggatatgatgttc cataagatctacatccagaaacatgacaacgtgagcatcctgttcgctgacattgagggc ttcaccagcctggcgtcccagtgcaccgcccaggagctggtcatgaccctcaacgagctc ttcgcccgcttcgacaagctggctgcggagaatcactgtttacgcattaagatcctgggg gattgctactactgcgtgtcggggctgcccgaagccagggccgaccacgcccactgctgc gtggagatgggcatggacatgatcgaggccatctcgttggtccgggaggtgacgggcgtg aacgtgaacatgcgcgtgggaattcacagcggccgagtgcactgcggtgtccttggcctg aggaagtggcagttcgacgtatggtctaatgacgtcacgctggccaaccacatggaggcc ggcggcaaggcaggacgcatccacatcaccaaggccaccctcaactacctgaacggcgac tacgaggtggagccaggctgcgggggcgagcgcaacgcctacctcaaggagcacagcatc gagaccttcctcatcctgcgctgcacccagaagcggaaagaagagaaggccatgatcgcc aagatgaaccgccagcgaaccaactccatcgggcacaacccgccacactggggggccgag cgccccttctacaaccacctgggtggcaaccaggtctccaaggagatgaagcggatgggc tttgaagaccccaaggacaagaacgcccaggagagtacgaaccccgaggatgaagtggat gagtttctgggccgggcaatcgacgccaggagcatcgacaggctgcggtccgagcacgtc cgcaggttcctcttgaccttcagggagcctgacttagagaagaagtactccaagcaggtg gacgaccgctttggtgcctacgtggcgtgtgcctcgctcgtcttcctcttcatctgctgt gtccagatcaccatcgtgccccactccatgttcatgctgagtttctacctggcctgcttc ctgctgctgaccttggtggtgtttgtgtccatgatctactcctgcgtgaagctcttcccg cgcccgctgcagagcctgtccaggaagatcgtgcgctccaagatgaacagcaccctggtc ggagtgttcaccatcaccctggtgttcctgtcggctttcgtcaacatgttcatgtgcaac tccaaggatctgctggactgcctggcggcggagcacaacatcagcgtgatccatgtcaac gcgtgccacgtggtggagtcggccttcaactacagcctgggcaacgagcagggcttctgt ggcaactccaggcccaactgcaacttccccgagtacttcacctacagcgtgctgctcagc ctgctggcctgctccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctg gccatcgagctcacctacgtgctcatcgtcgaggtgccccgggtcacgctctttgacaat gccgacctgctggtcaccgccaacgccatagacatcagcagcaacgggacctcccagtgc ccggagcacgcgaccaaggtggcgctgaaggtggtgacgcccatcataatctccgtcttt gtgctggccctgtacctgcacgcccagcaggtggagtccaccgcccgcctggacttcctc tggaaactgcaggccacggaggagaaggaggagatggaggagctgcaggcctacaaccgg cggctgctgcacaacatcctgcccaaggacgtggccgcccacttcctggcccgcgagcgg cgcaatgacgagctgtactaccagtcctgcgagtgcgtggccgtcatgttcgcctccatc gccaacttctccgagttctacgtggagctagaggccaacaacgagggcgtcgagtgcctg cggctgctgaacgagatcatcgccgactttgacgagatcatcagtgaggatcggttcagg cagctggagaagattaagaccatcggcagcacctacatggccgcctcgggcctcaacgac tccacctacgacaaggtgggcaagacacacatcaaagcgctggccgacttcgccatgaag ctgatggaccaaatgaaatacatcaacgagcactccttcaacaacttccagatgaagatc ggactcaacattggccccgtggtggctggggtgatcggggcacgtaagccccagtacgac atctggggcaacacagtgaacgtggccagccgtatggacagcaccggcgtgcccgaccgc atccaggtcaccacggacatgtaccaggtgctggccgccaacacataccagctggagtgc cggggtgtggtcaaggtcaagggcaaaggcgagatgatgacgtacttcctcaacggcggg cccccgctcagttag

Oryctolagus cuniculus (rabbit): 100337882 Help Entry 100337882         CDS       T03373                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04020   Calcium signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04720   Long-term potentiation ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04727   GABAergic synapse ocu04742   Taste transduction ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05032   Morphine addiction ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100337882 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100337882 (ADCY8)    04371 Apelin signaling pathway     100337882 (ADCY8)    04020 Calcium signaling pathway     100337882 (ADCY8)    04072 Phospholipase D signaling pathway     100337882 (ADCY8)    04024 cAMP signaling pathway     100337882 (ADCY8)    04022 cGMP-PKG signaling pathway     100337882 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100337882 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     100337882 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100337882 (ADCY8)    04062 Chemokine signaling pathway     100337882 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     100337882 (ADCY8)    04923 Regulation of lipolysis in adipocytes     100337882 (ADCY8)    04912 GnRH signaling pathway     100337882 (ADCY8)    04913 Ovarian steroidogenesis     100337882 (ADCY8)    04915 Estrogen signaling pathway     100337882 (ADCY8)    04914 Progesterone-mediated oocyte maturation     100337882 (ADCY8)    04921 Oxytocin signaling pathway     100337882 (ADCY8)    04926 Relaxin signaling pathway     100337882 (ADCY8)    04935 Growth hormone synthesis, secretion and action     100337882 (ADCY8)    04918 Thyroid hormone synthesis     100337882 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     100337882 (ADCY8)    04916 Melanogenesis     100337882 (ADCY8)    04925 Aldosterone synthesis and secretion     100337882 (ADCY8)    04927 Cortisol synthesis and secretion     100337882 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100337882 (ADCY8)    04270 Vascular smooth muscle contraction     100337882 (ADCY8)   09154 Digestive system    04970 Salivary secretion     100337882 (ADCY8)    04971 Gastric acid secretion     100337882 (ADCY8)    04972 Pancreatic secretion     100337882 (ADCY8)    04976 Bile secretion     100337882 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     100337882 (ADCY8)    04727 GABAergic synapse     100337882 (ADCY8)    04725 Cholinergic synapse     100337882 (ADCY8)    04720 Long-term potentiation     100337882 (ADCY8)    04723 Retrograde endocannabinoid signaling     100337882 (ADCY8)   09157 Sensory system    04742 Taste transduction     100337882 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     100337882 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     100337882 (ADCY8)    04213 Longevity regulating pathway - multiple species     100337882 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     100337882 (ADCY8)    04714 Thermogenesis     100337882 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100337882 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     100337882 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100337882 (ADCY8)    05163 Human cytomegalovirus infection     100337882 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     100337882 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100337882 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100337882 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100337882 (ADCY8) Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100337882 (ADCY8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  100337882 NCBI-ProteinID:  XP_002710595 Ensembl:  ENSOCUG00000002685 UniProt:  G1SI32 LinkDB All DBs Position 3:complement(146490149..146740431) Genome browser AA seq 1251 aa AA seqDB search MELSDVRFLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGG GSGGSGKGSNPAGCGSNHHAPQLSGESALPLYSLGPGERAHSTGGSKVFPERSGSGSASG SGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHT YLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTS LLQVVLQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEAR LRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADV KGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAH CCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKL ESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPED IVKESVSPSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHV QSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAF IVLLFITTIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINE NYLARNVIIFASILINFLGAVLNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTG VLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEA SLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVA RHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDE LLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKH SFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLIL KDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLV QSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPTGPEPGAQAEGTDKSDLP NT seq 3756 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgcttccttagcggcagcgaggaactctacaccatccacccg acgcccccggccggcgacggcgggagcggctcccggccgcagcggctgctgtggcagacg gcggtgcggcacatcaccgagcagcgtttcattcatgggcaccggggcggcggcggcggc gggagcggaggctccgggaaaggctcgaaccctgcgggctgcggctccaaccaccacgca cctcagctgtccggcgagtccgcgctgccgctctactcgctgggccccggggagcgggcg cacagcaccggtggctccaaagtcttcccggaacgcagcgggagcggcagcgccagtggc agcgggggtgggggtgacctgggcttcctgcaccttgactgcgccccgagcaactccgat ttctttctcaatgggggctatagctatcgaggggtcattttccccaccttgcgcaactcc ttcaagtcccgggatctggaacgcctgtaccagcgctatttcctgggccaaaggcgcaag tcggaggtggtgatgaacgtgctggatgtgctgaccaaactcaccctcctggtcctgcac ttgagcctggcctcagcacccatggacccgctcaaaggcatcctgttgggcttcttcact ggcatcgaggtggtgatctgtgccctggtggtggtcaggaaggacaccacctcgcacacg tacctgcagtacagcggcgtggtcacctgggtggccatgaccacccagatcctggcagca ggtctcggctacgggcttctaggtgatggcataggctacgtgctcttcacgctcttcgcc acgtacagcatgctgccgctgccgcttacctgggccattctggctggcctgggcacctcg ctgctgcaggtggtcctccaagtagtcatccctcggctggcagtcatttccatcaaccag gttgtggcccaggcagtgctattcatgtgtatgaacacggctggaatcttcatcagttac ctctcagaccgggcccagcgtcaagccttcctggaaacgcggaggtgtgtggaggccagg ctacgcctggagacagagaatcaaagacaggagcggctcgtgctgtctgtgctaccccga tttgttgtcctggaaatgatcaacgacatgaccaatgtggaagatgagcacctgcagcac cagttccatcgaatctacatccatcgttatgagaacgtcagtattctttttgcagatgtt aaaggatttaccaacctctccacgaccttgtccgctcaggagctggtcaggatgctcaac gagctctttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaaatc ctgggagactgctactactgtgtttccggactgcctgagccccgccaggaccatgcccac tgctgtgttgaaatgggcctcagcatgatcaaaaccatcaggtatgtccggtcgaggaca aagcatgatgtggatatgaggattggaatccactcgggctccgtgctatgtggtgtgctg ggcctgaggaagtggcagtttgatgtctggtcttgggatgtggacattgcaaataaactg gaatctggaggaatccctgggagaattcacatttccaaagccaccctggactgcctcaat ggtgactataatgtggaagaaggccatggaaaagaacgaaatgagttcttgaggaagcat aatatagagacctatttaattaagcagcctgaggagagtctgctctccctgccggaagac atcgtcaaggaatcggtgagcccctctgacaggagaaacagtggggcaacattcactgaa ggatcctggagccccgaactgccctttgataacattgtggggaagcagaatactctggct gccctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttgcatgtc cagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggc gataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctg gagcacaagtattctcaaatgagggatgaagtattcaagtcaaacttagtctgtgcattt attgttcttctatttatcacgacaatacaaagtttgcttccttcttcaagagtgatgcca atgaccatccagttctccattctgattatgctgcactcagctctggtcctgatcaccaca gcagaggattataagtgtttgcccctggtcctgaggaaaacttgctgttggattaacgag aactacttggcccggaacgtcatcatctttgcctccatcttgattaatttcctgggagcc gtcctaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttc aattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcaccgga gtgttggccatggtgacctgtgcagtgttcctccgacttaactctgtcctgaagctagct gtgctgctaatcatgatcgccatctatgccctgctgacagagaccatctacgctggcctc tttctgcgttatgacaacttgaaccacagtggcgaagatttcctggggaccaaagaagca tcactgttgctaatggccatgttcctccttgctgtattctaccacggacagcagctggag tacacagcccgcctggacttcctctggcgagtacaggccaaggaggagatcaatgaaatg aaggagctgagggaacacaatgagaacatgctccggaatatcttacccagccacgtggcc cgacatttcctggagaaagaccgagacaatgaggaactgtactctcaatcctatgatgcc gttggggtgatgtttgcctccatcccaggatttgcagacttttactctcagactgaaatg aataaccagggagtggaatgcctacggttgctgaatgagatcattgctgacttcgatgag ttgcttggtgaagaccggttccaggacattgaaaagatcaaaaccattggcagcacttac atggccgtgtcaggcctgtcaccagaaaaacagcaatgtgaagacaagtggggacatttg tgtgccctggccgacttctctctcgccctcactgaaagcatacaggagatcaacaagcat tccttcaacaattttgaactccggatcggcatcagccatggctcagtggttgctggtgtg attggcgctaagaaacctcaatatgacatttggggcaaaaccgtgaacctggccagccga atggacagcacaggggtgagcggacggatccaagtgccagaggagacctatctcatcctc aaggaccagggctttgcctttgactaccgaggggagatctacgtgaaaggcatcagtgaa caggaagggaaaatcaaaacgtactttctcctgggaagagtccaacccaacccattcatc ttgcccccaagaagactacccgggcagtactccttggctgcagtcgttctgggccttgtc cagtccctcaaccggcaaaggcagaagcagctactcaatgagaacaacaacacggggatc atcaaaggccattacaaccgacggactttgctgactcccactgggccggagcctggggcc caagctgaaggcactgacaaatccgatttgccataa

Oryctolagus cuniculus (rabbit): 100340877 Help Entry 100340877         CDS       T03373                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04020   Calcium signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04727   GABAergic synapse ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04961   Endocrine and other factor-regulated calcium reabsorption ocu04962   Vasopressin-regulated water reabsorption ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05032   Morphine addiction ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100340877 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100340877 (ADCY9)    04371 Apelin signaling pathway     100340877 (ADCY9)    04020 Calcium signaling pathway     100340877 (ADCY9)    04072 Phospholipase D signaling pathway     100340877 (ADCY9)    04024 cAMP signaling pathway     100340877 (ADCY9)    04022 cGMP-PKG signaling pathway     100340877 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100340877 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     100340877 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100340877 (ADCY9)    04062 Chemokine signaling pathway     100340877 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     100340877 (ADCY9)    04923 Regulation of lipolysis in adipocytes     100340877 (ADCY9)    04912 GnRH signaling pathway     100340877 (ADCY9)    04913 Ovarian steroidogenesis     100340877 (ADCY9)    04915 Estrogen signaling pathway     100340877 (ADCY9)    04914 Progesterone-mediated oocyte maturation     100340877 (ADCY9)    04921 Oxytocin signaling pathway     100340877 (ADCY9)    04926 Relaxin signaling pathway     100340877 (ADCY9)    04935 Growth hormone synthesis, secretion and action     100340877 (ADCY9)    04918 Thyroid hormone synthesis     100340877 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     100340877 (ADCY9)    04916 Melanogenesis     100340877 (ADCY9)    04925 Aldosterone synthesis and secretion     100340877 (ADCY9)    04927 Cortisol synthesis and secretion     100340877 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100340877 (ADCY9)    04270 Vascular smooth muscle contraction     100340877 (ADCY9)   09154 Digestive system    04970 Salivary secretion     100340877 (ADCY9)    04971 Gastric acid secretion     100340877 (ADCY9)    04972 Pancreatic secretion     100340877 (ADCY9)    04976 Bile secretion     100340877 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     100340877 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     100340877 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     100340877 (ADCY9)    04727 GABAergic synapse     100340877 (ADCY9)    04725 Cholinergic synapse     100340877 (ADCY9)    04723 Retrograde endocannabinoid signaling     100340877 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100340877 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     100340877 (ADCY9)    04213 Longevity regulating pathway - multiple species     100340877 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     100340877 (ADCY9)    04714 Thermogenesis     100340877 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100340877 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     100340877 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100340877 (ADCY9)    05163 Human cytomegalovirus infection     100340877 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     100340877 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100340877 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100340877 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100340877 (ADCY9) Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100340877 (ADCY9) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom DUF512 zf-C2HC_2 AC_N Motif Other DBs NCBI-GeneID:  100340877 NCBI-ProteinID:  XP_017193707 Ensembl:  ENSOCUG00000007904 LinkDB All DBs Position Un Genome browser AA seq 1352 aa AA seqDB search MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSCSSHPKHCKYSISSSCSSSGDS AGAPRRLGGGARLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL FYVGFACLLWSVYFAVHTRSKLIVMVAPALCFLAACVGFFLFTFTKLYARHYAWTSLVLT LLVFALTLAAQFQALTPLAGRADSSNHTPAAQPADTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVAYSVLFETFGYHFRNEDCFPWPGAPVLHWELLSRALLHLCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVFERLGQSVVADQLKGLKTYLISGQRAKESQCSCAEALLSGFEVIDGSRVS SGPRGQGTASSGSVSDLAQTVKTFDNLKTCPSCGITFAPKAEAGAEGGTVQNGCQDEPQG GTKASGGPSSKAQNGLLSPPQQEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDPELERSYRTSYQEEVIKNSPVKTF ASATFSSLLDVFLSTTVFLVLSATCFLKYGAAATPPPPAALAVFGAALLLEVLSLVVSIR MVFFLEDVMACTKRLLEWIAGWLPRHCVGAVLVSLPALAVYSHVTSEFETNIHFPVVTGS AVLVAVVHYCNFCQLSSWMRSSLATIVGAGPLLLLYISLCPDSPIVVSPLDAVQNFSSGR SPCNSSLLQDSKRPASLVGEELILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTTQCQDSSHPQEHLQILFE FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDNGVVPQHQLSISP DIRVQVDGSIGRSPTDEIATLVPSVQYSDKTSLGCENAQARDAHPSSKRPWKEPIKAEER CRFGKAIEKDDCEDVGLEEANELTKLDVSKSV NT seq 4059 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcatcaccacagcaccgaggtgagctgtgac tccagcggcgacagcaacagcgtgcgggtcaagatcaaccccaagcagctgtcctgcagc agccaccccaagcactgcaagtacagcatctcctccagctgcagcagctcgggggactcc gcgggcgcgccccgcaggctgggcggcggggcccgcctgcgccggcagaagaagctgccg cagctgttcgagagggcctcgagccgctggtgggaccccaagttcgactcggtgaacctg gaggaggcctgcctggagcgctgcttcccgcagacccagcgccgcttccggtacgcgctc ttctacgtcggcttcgcctgcctgctctggagcgtctatttcgccgtccacacgagatcc aagctgattgtcatggtggcgccggcgctctgcttcctcgcggcgtgtgtgggctttttt ctgtttaccttcaccaagctgtacgcccggcattacgcctggacctcgctggttctcacc ctgctggtgttcgccctgaccctggctgcgcagtttcaggctttgacgcctctggcgggc cgtgctgacagctccaatcacactcccgcggcccagcccgcagacacctgcttatctcaa gtggggagcttctccatgtgcatcgaagtgctctttttgctctacaccgtcatgcactta cctctgtacttgagcttgtttctgggggtggcctattctgttctgtttgagaccttcggg tatcacttccggaacgaagactgcttcccctggcctggagcgccggtcctgcactgggag ctgctgagcagggccctgctccacctgtgcatccatgccatcgggatccacctgttcatc atgtcgcaggtgcggtcccggagcaccttcctgaaggtgggacagtccatcatgcacggc aaagacctggaagtagaaaaagccctcaaagagaggatgattcattccgtgatgccgaga atcatagcggacgacttgatgaagcagggggacgaggagagtgagaattctgtcaagagg cacgccacctcgagccccaagaacaggaagaagaagtcctccatccagaaggctcccata gcgttccgcccttttaagatgcagcagattgaggaagtcagcattttgtttgcagacatc gtgggcttcaccaagatgagcgccaacaagtccgctcacgccctggtgggcctcctgaat gatctgtttggccgcttcgaccggctgtgcgaggagaccaagtgtgagaagatcagcacc ctgggagactgttactactgcgtggcgggctgtcccgagccccgggcagaccatgcctac tgctgtatagagatgggcttgggcatgatcaaagccatcgagcagttctgccaggagaag aaagaaatggtaaacatgcgcgtcggggtccacacggggaccgtcctgtgtggcatcctg ggcatgaggaggtttaagttcgacgtgtggtccaatgatgtgaatttggccaatctcatg gagcagctgggagtggccggcaaagtccacatttccgaagccaccgcaaaatacctagac gaccggtacgaaatggaagacgggaaagtgtttgagcgcctgggccagagcgtggtggct gaccagttgaaaggtttgaagacatacctgatatcgggtcagagagccaaggagtctcag tgcagctgtgcagaggccttgctttctggctttgaggtcattgacggctcacgggtgtcc tcaggccctaggggacaggggacagcatcatcagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccttcatgtggaatcacctttgctcccaaa gctgaagccggcgcagaaggcggcactgtccagaatggctgccaagatgagcctcagggc ggcaccaaggcttctggaggacccagctccaaagctcagaatggactcctgagccctccc cagcaggagaagctgaccaacagtcagacctccttgtgtgagatcctgcaggagaaagga aggtgggcgggggtgagcttggaccagtcggctctgcttccgctgagattcaagaacatc cgcgagaagaccgatgcccattttgtggacgttatcaaagaagacagcctgatgaaggat tatttttttaagccacccatcaatcagttcagcctgaacttcctggacccggagctggag cgatcctacagaaccagctatcaggaggaggtcataaagaactcccccgtgaagaccttc gccagcgccaccttcagctcgctcctggacgtgttcttgtccacgacggtgttcctggtt ctctccgccacctgcttcctgaagtatggggccgcggccacgcctcctccaccggccgcc ctggcggtctttggggcagccctgctgctggaggtgctgtccctcgtggtgtccatcagg atggtgttcttcctggaggacgtcatggcctgcacgaagcgtctgctggaatggatcgca ggctggctgccgcgccactgcgtgggagccgtgctggtgtccctgcctgccctcgctgtc tactcccatgtcacctcggaatttgagacaaacatacatttcccggtggtcacgggctcg gcggtgctggtcgccgtggtgcactactgtaatttctgccagctcagctcctggatgagg tcctccctggccaccatcgtgggggctgggccactgcttctgctctacatctcactgtgc ccggacagtcccatagtagtgtcacccctggacgcagtacagaatttcagctccgggagg agtccgtgcaatagctcgctgctgcaggacagcaagagaccagccagcctcgtgggcgag gagctgatcctcgtcttcttcctcctgctcctgctggtctggttcctgaaccgagagttc gaagtcagctaccgccttcactaccacggggacgtggaagcggatctgcaccgcaccaag atccagagcatgcgggaccaggccgactggctgctgaggaacatcatcccctaccacgtg gcggagcagctgaaggtatcccagacctactccaagaaccacgacagcggaggggtcatc tttgccagcatcgtcaacttcagcgagttctacgaggagaactacgagggcggcaaggag tgctaccgggtcctcaacgagctcatcggggacttcgacgagctgctgagcaagccagac tacagcagcatcgagaagatcaagaccatcggggccacgtacatggcggcttcggggctg aacaccacgcagtgccaggacagcagccacccccaggagcacctgcagatcctgttcgag ttcgccaaggagatgatgcgtgtggtggacgacttcaacaacaacatgctatggttcaac ttcaagctcagagtcggctttaaccacgggcccctcacggcgggggtcatcggcaccact aagctgctgtatgacatctggggggacaccgtcaacatcgccagcaggatggacaccaca ggcgtcgagtgccgcatccaggtgagcgaagagagctaccgtgtcctgagcaagatgggc tatgacttcgactacagagggacggtgaacgtcaaggggaagggccagatgaagacctac ctttaccccaagtgcacggacaacggggtcgtgccgcaacaccagctgtccatctccccg gacatccgcgtccaggtggatggcagcatcggacggtctcccacggacgagatcgccacc ctggtgccttctgtccagtattcggacaagacgtccctgggctgcgagaacgcgcaggcc agggacgcgcacccatcttccaagaggccctggaaagagcccatcaaagccgaagaaagg tgtcggtttggcaaagccatagagaaagatgactgtgaagacgtggggctggaggaagcc aacgaactcaccaagcttgacgtttccaagagcgtgtga

Oryctolagus cuniculus (rabbit): 100343958 Help Entry 100343958         CDS       T03373                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04020   Calcium signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04727   GABAergic synapse ocu04740   Olfactory transduction ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04962   Vasopressin-regulated water reabsorption ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05032   Morphine addiction ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100343958 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100343958 (ADCY3)    04371 Apelin signaling pathway     100343958 (ADCY3)    04020 Calcium signaling pathway     100343958 (ADCY3)    04072 Phospholipase D signaling pathway     100343958 (ADCY3)    04024 cAMP signaling pathway     100343958 (ADCY3)    04022 cGMP-PKG signaling pathway     100343958 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100343958 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     100343958 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100343958 (ADCY3)    04062 Chemokine signaling pathway     100343958 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     100343958 (ADCY3)    04923 Regulation of lipolysis in adipocytes     100343958 (ADCY3)    04912 GnRH signaling pathway     100343958 (ADCY3)    04913 Ovarian steroidogenesis     100343958 (ADCY3)    04915 Estrogen signaling pathway     100343958 (ADCY3)    04914 Progesterone-mediated oocyte maturation     100343958 (ADCY3)    04921 Oxytocin signaling pathway     100343958 (ADCY3)    04926 Relaxin signaling pathway     100343958 (ADCY3)    04935 Growth hormone synthesis, secretion and action     100343958 (ADCY3)    04918 Thyroid hormone synthesis     100343958 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     100343958 (ADCY3)    04916 Melanogenesis     100343958 (ADCY3)    04925 Aldosterone synthesis and secretion     100343958 (ADCY3)    04927 Cortisol synthesis and secretion     100343958 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100343958 (ADCY3)    04270 Vascular smooth muscle contraction     100343958 (ADCY3)   09154 Digestive system    04970 Salivary secretion     100343958 (ADCY3)    04971 Gastric acid secretion     100343958 (ADCY3)    04972 Pancreatic secretion     100343958 (ADCY3)    04976 Bile secretion     100343958 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     100343958 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     100343958 (ADCY3)    04727 GABAergic synapse     100343958 (ADCY3)    04725 Cholinergic synapse     100343958 (ADCY3)    04723 Retrograde endocannabinoid signaling     100343958 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     100343958 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     100343958 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     100343958 (ADCY3)    04213 Longevity regulating pathway - multiple species     100343958 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     100343958 (ADCY3)    04714 Thermogenesis     100343958 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100343958 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     100343958 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100343958 (ADCY3)    05163 Human cytomegalovirus infection     100343958 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     100343958 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100343958 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100343958 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100343958 (ADCY3) Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100343958 (ADCY3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  100343958 NCBI-ProteinID:  XP_017196407 Ensembl:  ENSOCUG00000015443 LinkDB All DBs Position 2:complement(173931464..174007512) Genome browser AA seq 1144 aa AA seqDB search MPRNQGFSEPEYSAEYSAEYSVSLPSDADRGVGRTHEISVRNSGACLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVGFAALFDCYVVVMCAVVFSSDKLAPLVVAGIGLLLDLV LFVVCKKGLLPDRLTRKAVPYLLWLLITAQIFSYLGLNFAQAHAASDTVGWQAFFLFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELQGMQLLREILANIFLYLCVIIVG VMSYYMADRKQRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVXXXXXXXVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGEGGSRCD YLEEKGIETYLIIASQPAVKAAAQNGLHGSALPNGAPASSKPSSPALIETKEPVGGSQAG SSTWEEPEQQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQ VVKKRNTFLLSMRFMDPDLESRYSEEKEKQSGAAFSCSCVVLLCTALVQILIDPWLMTNY VTFVVGEVLLLILTVCSLAAIFPRAFPKKLVAFSTWIDQTRWARNTWAMLAIFILVMANV VDMLSCLQDYAGPGNGTAGQELGGGCLENPKYYSYVAVLSLVATIMLVQVSHMVKLTLML LVTGAVAAINLTAWSPVFDEYDHRRFQEHGFPLVALEKMQVVSAPGLNGTDRLPLMPSKY SMTAMMLVMMLSFYYFSRHVEKLARTLFLWKMEVHDQKERVNEMRRWNEALVTNMLPEHV ARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFD SLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSDKERWQHLADLADFA LAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVM GNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAYPNGSSVTLPHQV VDNP NT seq 3435 nt NT seq  +upstreamnt  +downstreamnt atgcccaggaaccagggcttctcggagcccgagtactcggccgagtactccgccgagtac tcggtcagcctgccgtcggatgcggaccgcggcgtgggccggacgcacgagatctccgtg cggaactcgggcgcctgcctgtgtctgccccgcttcatgcggctgaccttcgtgccggag tccttggagaacctctaccagacctacttcaagcggcagcgccacgagaccctgctggtg ctggtgggcttcgcggccctcttcgactgctacgtggtggtcatgtgcgccgtggtcttc tcgagcgacaagctggcgccgctcgtcgtggctggcatcgggctgctgttggacctcgtg ctcttcgtggtctgcaagaaggggctgctgcccgaccggctcacccggaaggcggtgccc tacctgctgtggctgctgataacagcccagatcttctcctacctgggcctgaacttcgcg caggcccacgcggccagcgacacggtgggctggcaggccttcttcctcttctccttcttc atcacgctgccactcagcctcagccccatcgtcatcatctctgtggtctcctgtgtggtg cacacgctcgtcctgggggtcactgtggcccagcagcagcaggacgagctgcaggggatg cagctgctcagggagatcctggccaacatcttcctctacctgtgcgtcatcatcgtgggc gtcatgtcctactacatggccgaccgcaagcagcgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaacctcatgctg tccatcctgcccaagcacgtggccgatgagatgttgaaggacatgaagaaggatgagagc cagaaagaccagcagcagttcaacaccatgtacatgtaccgccacgagaatgtnnnnnnn nnnnnnnnnnnnnnngtgggcttcactcagctctcctctgcctgcagcgcccaggagctc gtgaagctgctcaacgagctctttgcccgcttcgacaagctggcggccaaataccaccag ctgcggatcaagatcctgggcgactgctactactgcatctgcgggctgcccgactaccgg gaggaccacgccgtgtgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgggagaagacgaagactggcgtggacatgcgtgtgggggtgcacacaggcactgta ctggggggcgtcctgggccagaagcgctggcagtacgacgtgtggtccaccgacgtcacc gtggccaacaagatggaggccggcggcatccccgggcgcgtgcacatctcccagagcacc ctggactgcctgaagggagagttcgacgtggagcccggcgaggggggcagccgctgcgac tacctggaggagaagggcatcgagacctacctcatcatcgcctcccagcccgccgtgaag gccgccgcccagaacggcctccacggctcggccctgcccaacggagcgccagcttcctcc aagcccagctcgcctgccctcattgagaccaaggagcccgtggggggcagccaggccggc agttccacgtgggaggagcccgagcagcaggaggcgcaggcggacaacccctccttcccc aaccctcgccggaggctgcgcctgcaggacctggccgaccgcgtggtggacgcctccgag gacgagcacgagctcaaccagctgctcaacgaggccctgctggagcgcgagtccgcccag gtggtgaagaagaggaacaccttcctcctgtccatgcggttcatggaccccgacctggag tcccgctactcggaggagaaggagaagcagagcggggccgccttcagctgctcctgcgtc gtcctgctgtgcacggccctggtgcagatcctcatcgacccctggctgatgacaaactac gtgacctttgtggtcggggaggtcctgctcctgatcctgaccgtctgctcgctggctgcc atctttccccgggcctttcctaagaagctggtagccttctccacgtggatcgaccagacc cgctgggccaggaacacctgggccatgctggccatcttcatcctggtgatggcaaatgtc gtggacatgctcagctgtctgcaggactacgcgggaccgggcaatggcacggcggggcag gagctggggggcggctgcctggagaaccccaagtattacagctacgtggccgtgctgtcg ctcgtcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctcatgctg ctcgtcacgggcgccgtggccgccatcaacctcaccgcctggagccccgtcttcgacgag tacgaccacaggcgcttccaggagcacggcttccccctggtggccctggagaagatgcag gtcgtttccgcccctgggctcaacggtaccgacaggctgccgctgatgccatccaagtac tcgatgacagcgatgatgctggtcatgatgctgagcttttactacttctcgcgccacgtg gaaaagctggcacggaccctgttcctgtggaagatggaggtccacgatcagaaggagcgt gtcaatgagatgcggcgctggaacgaggccttggtcaccaacatgctgcctgagcacgtg gcacgccatttcctggggtccaagaagagagacgaggagctgtacagccagtcctatgat gagatcggagtcatgttcgcctccctgcccaacttcgccgacttctacaccgaggagagc atcaacaatgggggcatcgagtgcctgcgcttcctcaacgagatcatctccgactttgac tctctcctggacaatcccaaatttcgggtcatcacgaagatcaaaaccattggcagcacc tatatggcggcttcgggagtcaccccagatgtcaacaccaacggctttaccagctccaac aaggaagagaagtcagacaaggagcgctggcagcacctggccgacctggccgacttcgca ctcgccatgaaggacacgctgaccaacatcaacaatcagtccttcaacaacttcatgctg cgcataggcatgaacaaaggaggggttctggctggcgtcatcggagcccggaaaccacac tatgacatctggggcaacactgtcaatgtggccagcagaatggagtccacaggggtcatg ggcaacattcaggtggtggaggaaacgcaagtgatcctgagagagtacggcttccgcttc gtgaggcgcggccccatctttgtgaaaggaaagggggaactgctgaccttcttcctgaag gggcgggacaagcccgctgcctaccccaacggctcctcggtgaccctgccccaccaggtg gtcgacaacccctga

Oryctolagus cuniculus (rabbit): 100346742 Help Entry 100346742         CDS       T03373                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04020   Calcium signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04727   GABAergic synapse ocu04742   Taste transduction ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05032   Morphine addiction ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100346742 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100346742 (ADCY4)    04371 Apelin signaling pathway     100346742 (ADCY4)    04020 Calcium signaling pathway     100346742 (ADCY4)    04072 Phospholipase D signaling pathway     100346742 (ADCY4)    04024 cAMP signaling pathway     100346742 (ADCY4)    04022 cGMP-PKG signaling pathway     100346742 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100346742 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     100346742 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100346742 (ADCY4)    04062 Chemokine signaling pathway     100346742 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     100346742 (ADCY4)    04923 Regulation of lipolysis in adipocytes     100346742 (ADCY4)    04912 GnRH signaling pathway     100346742 (ADCY4)    04913 Ovarian steroidogenesis     100346742 (ADCY4)    04915 Estrogen signaling pathway     100346742 (ADCY4)    04914 Progesterone-mediated oocyte maturation     100346742 (ADCY4)    04921 Oxytocin signaling pathway     100346742 (ADCY4)    04926 Relaxin signaling pathway     100346742 (ADCY4)    04935 Growth hormone synthesis, secretion and action     100346742 (ADCY4)    04918 Thyroid hormone synthesis     100346742 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     100346742 (ADCY4)    04916 Melanogenesis     100346742 (ADCY4)    04925 Aldosterone synthesis and secretion     100346742 (ADCY4)    04927 Cortisol synthesis and secretion     100346742 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100346742 (ADCY4)    04270 Vascular smooth muscle contraction     100346742 (ADCY4)   09154 Digestive system    04970 Salivary secretion     100346742 (ADCY4)    04971 Gastric acid secretion     100346742 (ADCY4)    04972 Pancreatic secretion     100346742 (ADCY4)    04976 Bile secretion     100346742 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     100346742 (ADCY4)    04727 GABAergic synapse     100346742 (ADCY4)    04725 Cholinergic synapse     100346742 (ADCY4)    04723 Retrograde endocannabinoid signaling     100346742 (ADCY4)   09157 Sensory system    04742 Taste transduction     100346742 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     100346742 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     100346742 (ADCY4)    04213 Longevity regulating pathway - multiple species     100346742 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     100346742 (ADCY4)    04714 Thermogenesis     100346742 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100346742 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     100346742 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100346742 (ADCY4)    05163 Human cytomegalovirus infection     100346742 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     100346742 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100346742 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100346742 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100346742 (ADCY4) Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100346742 (ADCY4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  100346742 NCBI-ProteinID:  XP_008267668 Ensembl:  ENSOCUG00000002958 LinkDB All DBs Position 17:complement(44361239..44377008) Genome browser AA seq 1086 aa AA seqDB search MARLFSPRPPPSDDLFYETYYSLSQQYPLLLLLLGIVLCALVALLGVAWASGRELISDPS FLSTVLCALGGFSLLLGLASREQRLQRWTRALSGLVWAALLALGHGFLFTGGVVSAWNQV SFFLFVIFTAYAMLPLGMRDAVAAGLASSLSHLLVLGLYLGPQPDSQPALLPQLAANAVL FVCGNAVGAYHKALMERALRATFREALSSLQSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPVSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGHELLRPSLLMT RYLESWGAAKPFAHLSHIDSPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDDELDTGDA KFFQVIEQLNSQKQWRQSKDFSPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNF IIQMLVTDRPPALAITYSITFLLFFLLLFVCFSEHLTKCVLKGPKMLHWLPTLSGLVATR PGLRVALGTATILLVFIMAITSLFFLPASLDCPPWAPNVSSIAFNLSWQLPGSLPLLSVP YSMHCCVLGSLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLIARLYVGPLD SRPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETEMMENLTR LLLENVLPAHVAPQFIGQKRRNEDLYHQSYECVCVLFASIPDFKEFYSESNINHEGLECL RLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQVQQQAHCQDAER SCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTV NVASRMESTGVLGKIQVTEETAQALQSLGYTCCIRGIIKVKGKGQLRTYFLNTDLTRTGP PSATLG NT seq 3261 nt NT seq  +upstreamnt  +downstreamnt atggcgcgcctcttcagcccccggccgcctcccagcgacgacctcttttacgagacctac tacagcttgagccaacagtacccgctactgctgctgctgctggggatcgtgctgtgcgcg ctcgtggcgctgctcggcgtcgcctgggccagcggcagggagctgatctcagacccgagc ttcctaagcaccgtgctgtgcgcgctgggcggcttctcgctgctgctgggcctggcttcc cgcgagcagcgacttcagcgctggacgcgcgccctgtccggcctcgtgtgggccgcgctg ctagcgctcggccacggcttcctgttcacagggggcgtggtgagcgcctggaaccaggtg tcctttttcctcttcgtcatcttcacggcgtatgccatgctgcccttggggatgcgggac gcggtcgctgcaggcctggcctcttcactctcgcacctgctggtcctggggctgtacctt gggccacagcctgattcgcagccggcgctgctgccgcagcttgcagccaacgcagtgctg ttcgtgtgtgggaacgcggtgggggcgtaccacaaagcgctgatggagcgtgccctgcgc gccaccttccgcgaggcgctcagctccctgcagtcgcgccggcggctggacaccgagaag aagcaccaggaacacctgctgttgtccatccttcctgcctacctggccagggagatgaag gcagagatcatggctcggctgcaggctggacaggggtcccggccagagagcaccaacaac ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcaccaggctggccagcgagtgctcccccaaggagctggtgctcatgctcaacgag ctctttggaaaattcgaccagatcgccaaggagcacgaatgcatgcggatcaagatccta ggggactgctactactgtgtctccgggcttccagtctccctgccagaccatgccatcaac tgcgtacgcatggggctggacatgtgccgggccatcaggaaactgcgggcagccactggt gtagatatcaacatgcgtgtgggcgtgcactcgggcagcgtgctctgcggagtcatcggc ctgcagaagtggcagtacgatgtctggtcccatgacgtcacactggccaaccacatggag gcaggcggcgtgccaggacgagtgcacatcacgggggccacgctggctctgctggccggg gcttacgcagtggaggacgcagccatggaacaccgggacccgtaccttcgagagctaggg gagccgacctacctggtcattgatccccgggccgaggaggaggacgagaagggcacagca ggagggctgctgtcctctctcgagggccacgagctgctgcgtccgtctctgctgatgacc cgctacctggagtcgtggggtgcagccaagccttttgcccacctgagccacatagacagc cctgtgtccacctccacccctctcccggagaaggccttggcttccttcagcccccagtgg agcctggaccggagccgtaccccccggggcctagacgatgagctggacaccggggatgcc aagtttttccaggtcatcgaacagctcaactctcagaaacaatggaggcagtcgaaggac ttcagcccactgacgctctacttcagagagaaggagatggagaaggagtaccgtctctcc gcactccctgccttcaagtactatgcagcctgcaccttcctggtttttctctccaacttc atcatccagatgctggtgacagacaggcccccagctctggccatcacctacagcatcacc ttcctcctcttcttcctcctgctcttcgtctgcttctcagagcacctgacgaagtgtgtc ctgaagggccccaagatgctgcactggctgcccacactgtccggcctggtagccacacgc cctggactgcgagtggccctgggcactgccaccatcctcctcgtcttcatcatggccatt accagcctgttcttcctaccagcatcgctggactgtccaccctgggctcccaatgtgtcc tccattgctttcaacctctcctggcagctccctgggtccctgcccctcctcagtgtccca tactccatgcactgctgcgtgctgggctccctgtcctgctccctctttctgcacatgagc ttcgaactcaagctgctgctgctgctgctctggctcgtggcctcctgctccctcttcctg cactcccacgcctggctgtccgactgcctcatcgcccgcctctacgtgggacccttggac tccaggccgggcgtgctgaaggagcccaagctgatgggagccatctccttcttcatcttc ttcttcaccctccttgtcctggctcgacagaatgagtattactgccgcctggacttcctg tggaagaagaagctgaggcaagagcgcgaggagacagagatgatggagaatctgacccgg ctgctcttggagaacgtgctccctgcacacgtggccccccagttcattggccagaaacgg cgcaacgaggacctctaccaccagtcctacgagtgtgtttgtgtcctcttcgcctccatc ccagactttaaggagttctactcggaatccaacatcaaccacgaagggctcgagtgtttg cggctactcaatgagatcattgctgatttcgatgagctgctctccaagcccaagttcagc ggggtggagaagatcaaaaccatcggcagcacctacatggcagccacaggcttaaacgcc acctctggccaggatgcccaacaggtccagcaacaggcccactgccaggatgctgagcga agctgcagccaccttggcaccatggtggaatttgcagtggccctggggtccaagctagac gtcatcaacaagcactcgttcaacaacttccgcctgcgtgtggggctgaaccacggacca gtagtggctggagtcattggggcccagaagccacaatatgacatctggggcaacacggtg aatgtggccagccgcatggagagcaccggagtcctgggcaaaatccaggtgactgaggag acagcccaggccctgcagtcgctgggctacacctgctgcattcggggcatcatcaaggtc aaaggcaaagggcagctgcgcacctacttcctgaacacggacttgacgcgaactgggcct ccctcagccaccctgggctga

Oryctolagus cuniculus (rabbit): 100354934 Help Entry 100354934         CDS       T03373                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04727   GABAergic synapse ocu04742   Taste transduction ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04924   Renin secretion ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04961   Endocrine and other factor-regulated calcium reabsorption ocu04962   Vasopressin-regulated water reabsorption ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05032   Morphine addiction ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100354934 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100354934 (ADCY6)    04371 Apelin signaling pathway     100354934 (ADCY6)    04072 Phospholipase D signaling pathway     100354934 (ADCY6)    04024 cAMP signaling pathway     100354934 (ADCY6)    04022 cGMP-PKG signaling pathway     100354934 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100354934 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     100354934 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100354934 (ADCY6)    04062 Chemokine signaling pathway     100354934 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     100354934 (ADCY6)    04923 Regulation of lipolysis in adipocytes     100354934 (ADCY6)    04912 GnRH signaling pathway     100354934 (ADCY6)    04913 Ovarian steroidogenesis     100354934 (ADCY6)    04915 Estrogen signaling pathway     100354934 (ADCY6)    04914 Progesterone-mediated oocyte maturation     100354934 (ADCY6)    04921 Oxytocin signaling pathway     100354934 (ADCY6)    04926 Relaxin signaling pathway     100354934 (ADCY6)    04935 Growth hormone synthesis, secretion and action     100354934 (ADCY6)    04918 Thyroid hormone synthesis     100354934 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     100354934 (ADCY6)    04916 Melanogenesis     100354934 (ADCY6)    04924 Renin secretion     100354934 (ADCY6)    04925 Aldosterone synthesis and secretion     100354934 (ADCY6)    04927 Cortisol synthesis and secretion     100354934 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100354934 (ADCY6)    04270 Vascular smooth muscle contraction     100354934 (ADCY6)   09154 Digestive system    04970 Salivary secretion     100354934 (ADCY6)    04971 Gastric acid secretion     100354934 (ADCY6)    04972 Pancreatic secretion     100354934 (ADCY6)    04976 Bile secretion     100354934 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     100354934 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     100354934 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     100354934 (ADCY6)    04727 GABAergic synapse     100354934 (ADCY6)    04725 Cholinergic synapse     100354934 (ADCY6)    04723 Retrograde endocannabinoid signaling     100354934 (ADCY6)   09157 Sensory system    04742 Taste transduction     100354934 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     100354934 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     100354934 (ADCY6)    04213 Longevity regulating pathway - multiple species     100354934 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     100354934 (ADCY6)    04714 Thermogenesis     100354934 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100354934 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     100354934 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100354934 (ADCY6)    05163 Human cytomegalovirus infection     100354934 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     100354934 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100354934 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100354934 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100354934 (ADCY6) Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100354934 (ADCY6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  100354934 NCBI-ProteinID:  XP_017197314 Ensembl:  ENSOCUG00000007394 UniProt:  G1SSZ0 LinkDB All DBs Position 4:complement(33095161..33114188) Genome browser AA seq 1164 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQQRLRRGTRAAGFCAPRYMSCLQDAEPPSPTPAAPR RCPWQDEAFIRRGGPGPGKGVELGLRAVALGFEDAELTAATGVTEVAPRRGRSCWRRLAQ VFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLAFHAVPGSPQPAYVALL AGAATLFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPHSPSAGLWCPMF FVYITYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDALLWKQLGANVLLFLCTNLIGI CTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKED MMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIK ILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGV LGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKE QHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRTFSRTKDSKAFRQMGI DDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRK VDPRFGAYVACALLVFCFICFIQLLVFPHSTLMLGIYAGIFLFLLVTVLTCAVYSCGSRF PRVLQRLSRGIVRSRAHSTAVGIFSVLLVFTSAIANMFNCSHTPIRMCVAQMLNLTPSDV TACHLQQLNYSLDLDAPLCEGTTPPCSFPEYFVGNMLLSLLASSVFLHISSIGKLAMILV LGLIYLVLLLLGPPATIFDNYDLLLSVHGLASSNETLDGLDCPAAGRVALKYMTPVILLV FALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARE RRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEEQF RQLEKIKTIGSTYMAASGLNASTYDQVGRSHVTALADYAMRLMEQMKHINEHSFNNFQMK IGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLE CRGVVKVKGKGEMTTYFLNGGPSS NT seq 3495 nt NT seq  +upstreamnt  +downstreamnt atgtcctggtttagcggtctcctggttcccaaagtggatgagcggaaaacagcctggggc gaacgcaatgggcagcagcgcctgcgccgtgggactcgggccgccggcttctgcgcacct cgctatatgagctgcctccaggatgcagagccacccagccctaccccagccgctccccgg aggtgcccctggcaggatgaggccttcatccgcagggggggcccgggcccggggaagggc gtggagctggggctgcgggcagtggccctgggcttcgaggacgcggagctgacggcagcg acgggggtgactgaggtggcaccgcggcgcgggcgatcgtgctggcgccgcctggcgcag gtgttccagtccaagcagttccgctcggccaagctggagcgcctataccagcgctacttc ttccagatgaaccagagcagcctcacgctgctgatggcggtgctggtgctgctcatggct gtgctgctggctttccacgctgtgcctggcagccctcagcctgcctacgtggccctgttg gctggggccgccaccctgttcgtagcgctcatggtggtgtgtaatcggcatagcttccgc caggactccatgtgggtggtgagctacgtggtgctgggcatcctggctgccgtgcaggtc gggggcgccctggcagccgacccgcacagcccgtctgcgggcctctggtgccccatgttc ttcgtctacatcacctacaccctcctgcccatccgaatgcgggctgccgttctcagcggc cttggcctttccactctgcatttgatcttagcttggcaactcaaccgtggcgatgccttg ctttggaagcagcttggtgccaacgtgctgctgttcctctgcaccaacctcattggtatc tgcacacactacccagccgaggtgtctcagcgccaggcttttcaggagacccgtggttac atccaggcccggctgcacctgcagcacgagaaccggcagcaggagcggctgctgctgtcc gtgttgccccagcatgttgccatggagatgaaagaagacattaacacaaaaaaggaagac atgatgttccacaagatctacatccagaagcatgacaatgtcagcatcctgtttgccgac atcgagggctttaccagcctggcctcccagtgcaccgcacaggagctggtcatgactttg aatgagctctttgcccggtttgacaaactggccgcggagaatcactgcctgaggatcaag atcttaggggactgttactactgtgtgtcagggctgccagaggcccgggcagaccatgcc cactgctgtgtggagatgggggtggacatgatcgaggccatctcgctagtgcgtgaggtg acaggtgtgaatgtgaacatgcgcgtgggtatccacagtggtcgtgtgcactgcggtgtc cttggcctgcggaagtggcagttcgatgtgtggtccaacgacgtgaccctggccaaccac atggaggccgggggccgggccggccgcatccacatcactcgggccacactgcagtacctg aacggggactacgaggtggagcctggccgtggtggtgagcgcaatgcatacctcaaggag cagcacatagagaccttcctcatcctgggtgccagccagaaacggaaagaggaaaaggcc atgctggctaagctacagcggacgcgggccaattccatggagggtctgatgccacgctgg gtgcctgaccgcactttctcccgcaccaaggattccaaggccttccgccagatgggcatt gatgattccagcaaagacaaccggggtgcccaggatgctctgaaccctgaggatgaggta gatgaattcctgggccgtgccatcgatgcccgcagcatcgatcagctgcgcaaggaccac gtgcgccggttcctgctcaccttccagagagaggatctagagaagaagtactcgcggaag gtggacccccgctttggagcctacgtcgcctgtgccctgctcgtcttctgcttcatttgc ttcatccagctcctcgtcttcccccattcaaccctgatgctcgggatctatgccggtatc ttcctgttcctgctggtcactgtgctcacctgtgccgtgtactcctgtggttctcggttc cccagggtgctgcagcgcctgtctcgcggcattgtccgctcgcgggcacacagcacagca gttggcatcttttcagtcttgcttgtgtttacctccgccatcgccaacatgttcaactgc agccacacccccatacggatgtgcgtggcccagatgctgaatttaactccctccgacgtt actgcttgccacctgcagcagctcaattactctctggacctggatgcgcccctgtgtgag ggcaccacacccccctgcagcttccctgagtacttcgttgggaacatgctgctgagtctc ctggccagctctgtcttcctgcacatcagcagcatcgggaagctggccatgatcttagtc ttggggctcatctatctggtgctgcttcttctgggtcccccagccaccatctttgacaac tatgacctgctgcttagcgtccatggcttggcttcttctaatgagaccttggatgggctg gactgcccagctgcagggagggtggccctcaaatacatgacccctgtgatcctgctggtg tttgcgctggcactgtatctgcatgcccagcaggtggagtctacagctcgtctggacttc ctctggaaactgcaggcaacaggggagaaggaggagatggaggagctccaggcgtacaac cggcggctgctgcataacattctccccaaggatgtggctgcccacttcctggccagggag cgccggaatgatgagctctactaccagtcgtgtgagtgtgtggccgtgatgtttgcctcc atcgccaacttctctgagttctacgtggagctggaggccaacaatgagggcgtcgagtgc ctgcggctgctcaacgagatcatcgctgactttgacgagatcatcagcgaggagcagttc cggcagctggagaagatcaagactataggcagcacctacatggctgcctcggggctgaat gccagcacctatgaccaggtgggccgctcccacgtcaccgccctggctgactacgccatg cggctcatggagcagatgaagcacatcaatgagcactccttcaacaacttccagatgaag atcgggctgaacatgggcccagttgtggccggtgtcattggggcccggaagccgcagtat gacatctgggggaacacggtgaatgtctctagccgtatggacagcacaggggtccctgac cgaatccaggtgaccacggacctgtaccaggttctagctgccaagggctaccagctggag tgtcgaggggtggtcaaggtgaagggcaaaggggagatgaccacctacttcctcaatggg ggccctagcagttag

Oryctolagus cuniculus (rabbit): 100357357 Help Entry 100357357         CDS       T03373                                  Symbol ADCY7 Name (RefSeq) adenylate cyclase 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04020   Calcium signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04727   GABAergic synapse ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05032   Morphine addiction ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100357357 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100357357 (ADCY7)    04371 Apelin signaling pathway     100357357 (ADCY7)    04020 Calcium signaling pathway     100357357 (ADCY7)    04072 Phospholipase D signaling pathway     100357357 (ADCY7)    04024 cAMP signaling pathway     100357357 (ADCY7)    04022 cGMP-PKG signaling pathway     100357357 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100357357 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     100357357 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100357357 (ADCY7)    04062 Chemokine signaling pathway     100357357 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     100357357 (ADCY7)    04923 Regulation of lipolysis in adipocytes     100357357 (ADCY7)    04912 GnRH signaling pathway     100357357 (ADCY7)    04913 Ovarian steroidogenesis     100357357 (ADCY7)    04915 Estrogen signaling pathway     100357357 (ADCY7)    04914 Progesterone-mediated oocyte maturation     100357357 (ADCY7)    04921 Oxytocin signaling pathway     100357357 (ADCY7)    04926 Relaxin signaling pathway     100357357 (ADCY7)    04935 Growth hormone synthesis, secretion and action     100357357 (ADCY7)    04918 Thyroid hormone synthesis     100357357 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     100357357 (ADCY7)    04916 Melanogenesis     100357357 (ADCY7)    04925 Aldosterone synthesis and secretion     100357357 (ADCY7)    04927 Cortisol synthesis and secretion     100357357 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100357357 (ADCY7)    04270 Vascular smooth muscle contraction     100357357 (ADCY7)   09154 Digestive system    04970 Salivary secretion     100357357 (ADCY7)    04971 Gastric acid secretion     100357357 (ADCY7)    04972 Pancreatic secretion     100357357 (ADCY7)    04976 Bile secretion     100357357 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     100357357 (ADCY7)    04727 GABAergic synapse     100357357 (ADCY7)    04725 Cholinergic synapse     100357357 (ADCY7)    04723 Retrograde endocannabinoid signaling     100357357 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100357357 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     100357357 (ADCY7)    04213 Longevity regulating pathway - multiple species     100357357 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     100357357 (ADCY7)    04714 Thermogenesis     100357357 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100357357 (ADCY7)    05207 Chemical carcinogenesis - receptor activation     100357357 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100357357 (ADCY7)    05163 Human cytomegalovirus infection     100357357 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     100357357 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100357357 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100357357 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100357357 (ADCY7) Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100357357 (ADCY7) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  100357357 NCBI-ProteinID:  XP_008273270 Ensembl:  ENSOCUG00000003091 UniProt:  G1SJ05 LinkDB All DBs Position Un Genome browser AA seq 1080 aa AA seqDB search MPAKGRYFLNEGEEGPDQAALYEKYRLTSQHGPLLLTLLVAATAACCALIAIAFSHGDPS QHQAVLATAFLALAVFVAVYVLVYVECLVRRWLRAVALLTWACLLTLGYVLVFDSRTKQA CAWEQVPFFLFIIFVVYTLLPFSTQGAVAVGVVSTASHLLVIGAVMGVFTTPSAQVGLQL LANAVIFLCGNFTGAFHKHQLQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH ISMGMKLAIIERLKEHGDRRYLPDNNFHSLYVKRHRNVSILYADIVGFTRLASDCSPKEL VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCEAIKQ VREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT LSHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQQLPRPRGDAALKMRA SVRMTRYLESWGAARPFAHLNHRESVSSGETPVPSGRRPKAIPLRRHRTPDRSASPRGRA EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKDFEREYRLAPVPRARYDFACA GLIFVCILLVHLLVMPRTVALGVSFGLVACVLALVLGLCFATELLRGCLAPGTRRAISER VETQPLLRLTLAVLTIGSLLTVAVINLPLMPLPALGLPGGNETSPETLSGKDATLCAVLP YYTCTCILGFVACSVFLRMSLELKLVLLTVALVAYLLLFNLSPCWQWDCCGSGLGNLTTG NGTLSSTPTCSWRDLNTMINFYLVLFYGTLVMLSRQIDYYCRLDCLWKKKFKKEHEEFET MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVTPGHENQDLERQHTH IGVMVEFSMALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS RMESTGELGKIQVTEETCTILQALGYSCECRGLINVKGKGELRTYFVCTDTAKCQGLGLN NT seq 3243 nt NT seq  +upstreamnt  +downstreamnt atgccggccaaggggcgctacttcctcaacgagggcgaggagggcccggaccaggcggcg ctctatgagaagtaccggctcaccagccagcacgggccgctgctgctcaccctgctggtg gccgccaccgccgcctgctgcgccctcatcgccatcgccttcagccatggggacccctct cagcaccaggctgtgctggccacggcgttcctggcgctcgccgtgtttgtggctgtctac gtgctggtgtacgtcgagtgccttgttcggcgctggctcagggcggtggcgctgctcacc tgggcctgcctgctgacgctgggctatgtgctggtgttcgactcgcggacgaagcaggcc tgtgcgtgggagcaggtgcccttcttcttgttcatcatcttcgtggtgtacacgctgctg cccttcagcacgcagggagctgtggccgtgggggtcgtctccaccgcctcccacctgttg gtgatcggcgccgtgatgggggtcttcaccacgcccagcgcccaggtggggctacagctg ctggccaatgctgtcatcttcctgtgcggcaacttcacgggcgccttccacaagcaccag ctgcaggatgcctcccgcgacctcttcacctacacggtcaagtgcatccagatccgccgg aagctgcgcattgagaagcgtcagcaggagaacctgctgctgtctgtgctgccggcgcac atctccatgggcatgaagctggccatcatcgagcggctcaaggagcacggggaccgccgc tacctgcccgacaacaacttccacagcctctacgtcaagcggcaccggaacgtcagcatc ctctacgcggacatcgtgggcttcacgcgcctggccagcgactgctcccccaaggagctg gtggtggtgctcaacgagcttttcggcaagtttgaccagatcgccaaggccaacgagtgc atgcggatcaagatcctgggtgactgctactactgcgtgtcgggcttgcccgtgtccctg cctacccacgcccggaactgtgtgaagatggggctggacatgtgtgaggccattaagcag gtgcgggaggccacgggcgtggacatcagcatgcgtgtgggcatacactcggggaacgtg ctgtgtggcgtcatcgggctgcgcaagtggcagtacgacgtgtggtcccacgacgtgtcg ctggccaacaggatggaggcggctggagtccccggccgggtgcacatcacagaggcgacg ctgagccacctggacaaggcgtacgaggtggaggacgggcacgggcagcagcgtgacccc tacctgaaggagatgaacatccgcacctacctggtcattgacccccggagccagcagccg cccccacccagccaacagctgcccaggccccggggggatgcggccctgaagatgcgggcg tccgtgcgcatgacccgctacttggagtcctggggggcggcgcggcccttcgcacacctc aaccaccgcgagagcgtgagcagcggcgagacccccgtccccagtggccggaggcccaag gccattcccctacggcgccaccggacccctgacaggagcgcatcccccagggggcgggcg gaggacgactcctatgatgacgagatgctgtcagccatcgaggggctcagctccaccagg ccctgctgctccaagtctgacgacttctacacctttgggtccatcttcctggagaaggac tttgaacgagagtaccgcctggcgcctgtgccccgtgcccgctacgactttgcctgcgct ggcctcatctttgtctgcatcctgctagtccacctcctggtgatgcccaggacggtggcc ctgggtgtgtcctttgggctggtggcctgcgtgctggcgctggtgctaggcctgtgcttt gccacagagctcttgaggggctgcctggcccccgggacgcgccgggccatctcggagcgg gtggagacgcagcccctgctgaggctgaccctggccgtgctcaccatcggcagcctgctc actgtggccgtcatcaacctgcccctgatgcctctcccagccttggggctgcctggtggc aacgagacgagcccagagaccttgagcggcaaggatgcgaccctgtgtgcggtcctcccg tattacacctgcacttgcatcctgggcttcgtggcttgctcggtcttcctgcggatgagc ctggagctgaagttggtgctgctgacagtggccctggtggcctacctgctgctcttcaac ctctccccctgctggcagtgggactgctgcggctcgggcctgggcaacctcaccacgggc aatggcaccctcagcagcacccccacctgttcctggagggatctgaataccatgatcaac ttctacctggtcctgttttacggcaccctggtcatgctctccagacagatcgactactac tgccgcctggactgtctgtggaagaagaagttcaagaaggagcacgaggagtttgaaacc atggagaacgtgaaccgcctgctcctggagaacgtgctgccagcccacgtggccgcccac ttcattggggacaaactcaacgaggactggtaccatcagtcctacgactgcgtctgcgtc atgtttgcctccgtgccggacttcaaggtgttctacaccgagtgcgacgtcaacaaggag gggctggagtgtctgcggctgctcaacgagatcatcgccgacttcgatgagctgctgctg aagcccaagttcagcggcgtggagaagatcaagactatcggcagcacgtacatggcggct gcggggctcagcgtcaccccagggcacgagaaccaggacctggagcggcagcacacccac atcggcgtcatggtggagttcagcatggccctgatgagcaagctggatggcatcaaccgg cactccttcaactccttccgcctgcgagtcggcataaaccacgggccggtgattgctgga gtgattggggctcggaaacctcagtatgacatctggggaaacacagtcaatgttgccagc cgaatggagagcaccggagaactcggcaaaatccaggtgacagaagagacctgcaccatc ctccaggcactgggctactcctgcgaatgccggggactgatcaatgtcaaaggcaaaggc gaactgaggacttactttgtctgtacagacactgccaagtgtcaagggctggggctcaac tga

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