KEGG   Oryctolagus cuniculus (rabbit): 100339977
Entry
100339977         CDS       T03373                                 
Name
(RefSeq) retinoblastoma-like protein 2 isoform X1
  KO
K16332  retinoblastoma-like protein 2
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04068  FoxO signaling pathway
ocu04110  Cell cycle
ocu04151  PI3K-Akt signaling pathway
ocu04218  Cellular senescence
ocu05165  Human papillomavirus infection
ocu05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    100339977
   04151 PI3K-Akt signaling pathway
    100339977
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    100339977
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100339977
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ocu03000]
    100339977
Transcription factors [BR:ocu03000]
 Eukaryotic type
  Other transcription factors
   Pocket domain Rb
    100339977
SSDB
Motif
Pfam: RB_A RB_B DUF3452 TFIIB
Other DBs
NCBI-GeneID: 100339977
NCBI-ProteinID: XP_008255517
Ensembl: ENSOCUG00000006354
UniProt: G1SQV1
LinkDB
Position
5:9810669..9870402
AA seq 1140 aa
MPSGSDQSPPPPPVPPAAAASDEEEDEDGEAEETAQSAGSPTPQIQQRFDELCSRLNMDE
AARAEAWDSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTVEGNYVSLTRILRC
SEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEE
QPRQQRGRKQRRQPCTVSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNA
LQCSHRKELVNPNFKGLSEDFHAKDYKPSSDPPCVIEKLCSLHDGLVLEAKGIKEHFWKP
YIRKLYEKKLLKGKEENLTGFLDPGNFGESFKAINKAYEEYVLSVGNLDERVFLGEDAEE
EIGTLSRCLNAGSGTETAERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCVTPVS
TATHSLSRLHTMLTGLKNAPSEKLEQILRTCSRDPTQAIANRLKEMYEIYSQHSQPDEDF
NNCAKETASKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACCLEVV
TFSYKPPGNFPFITEIFDVPLYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWK
SDSPLWDRIRDNENRVPACEEVMPPQNLERADEICITGSPLTPRRVSEVRADTAGLGRSI
TSPTTLYDRYSSPTASTTRRRLFVDNDSPSDGGTPGRIPPQPLVNAVPVQNVSGEPVSVT
PVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQTVAGSLQPL
SAQALAGSLSSHQVTGTTLQVPGQVAIQQISPGGQPPKQGQPLTSSNIRPRKTSSLSLFF
RKVYHLAGVRLRDLCAKLDISDELRKKIWTCFEFSIIQCPELMMDRHLDQLLMCAIYVMA
KVTKDDRSFQNIMRCYRTQPQARSQVYRSVLIKGKRKRRNSGSSDSRSHQNSPTELNRDR
TSRDSSPVMRSSSTLPVPQPSSAPPTPTRLTGANSDMEEEERGDLIQFYNNVYIKQIKTF
AMKYSQANVMDAPPLSPYPFVRTGSPRRIQLSQNHPVYISPHKNETMLSPREKIFYYFSN
SPSKRLREINSMIRTGETPTKKRGILLEDGSESPAKRICPENHSALLRRLQDVANDRGSH
NT seq 3423 nt   +upstreamnt  +downstreamnt
atgccgtcgggaagcgaccagtcgccgccgcccccgcctgtgcccccggcggctgcggcc
tccgatgaggaggaggacgaggacggcgaggcggaggaaaccgcgcagtcggccggatcg
ccgaccccgcagatccagcagcggttcgacgagctgtgcagccgcctcaacatggacgag
gcggcgcgggccgaggcctgggacagctaccggagcatgagcgagagctacactttggag
ggaaatgatcttcactggttagcttgtgccttatatgtggcttgcagaaaatctgttcca
actgtaagcaaagggacagttgaaggaaactatgtatctttgactagaatcctgcgatgc
tcagagcagagcctaattgaattttttaacaagatgaagaagtgggaagacatggcaaat
ctaccgccacacttcagagaacgtactgagagattagaaaggaatttcactgtttctgcg
gtaatttttaagaaatatgaacccatttttcaggacatttttaaatatcctcaagaggag
caacctcgtcaacaaagaggaagaaaacagcggcgacagccctgtacggtgtctgaaatt
ttccatttttgttgggtgctttttatatatgcaaaaggtaatttccccatgattagtgat
gacttggtcaattcttaccatcttctgttatgtgctttggacttagtttatggcaatgcc
cttcagtgttcccatcgtaaagaacttgtgaacccaaattttaaaggcttatctgaagat
tttcatgctaaggattataaaccttcctccgacccaccttgtgtcattgagaaactctgt
tccttacacgatggcctggttttggaagcaaagggaataaaggaacatttttggaagcct
tatattaggaaactttatgaaaaaaagctacttaagggaaaagaagaaaatcttactggg
tttttagaccctgggaattttggcgagagctttaaagccatcaataaagcctatgaggag
tatgttctatctgttgggaatttagatgaacgtgtatttcttggagaggatgctgaggag
gaaattggaactctctcgaggtgtctgaacgctggttcaggaacagagactgctgaaagg
gtgcagatgaaaaacatattacagcaacattttgacaagtccaaagcacttagaatctct
acaccacttactggtgtgagatacattaaggagaacagtccttgtgtgaccccagtttct
acagcaacacacagcttgagtcgtctgcatacgatgctgacaggcctcaagaatgcacca
agtgagaaactggaacagattctgaggacatgttccagagatccaacccaggccattgct
aacaggttgaaagaaatgtatgaaatatattctcagcattcccagccagatgaggacttt
aataattgtgctaaagaaacggccagcaaacattttcgttttgcagaaatgctttactat
aaagtattagaatctgttattgaacaagaacaaaaaagactaggagacatggatttatct
ggtattctggaacaagatgcattccacagatcactcttggcctgctgccttgaggtcgtc
actttttcttataagcctcctgggaattttccatttattactgaaatatttgatgtgcca
ctttatcatttttataaggtgatagaagtattcattagagcagaagatggcctctgtaga
gaagtggtgaaacaccttaatcagattgaagaacaaatcttagatcatttggcgtggaaa
tcagactccccactctgggatagaattagagacaatgaaaacagagttcctgcatgtgaa
gaggtcatgccaccacagaatctggaaagagctgatgaaatttgtattactggttcccct
ttgactcccagaagggtgagtgaagttcgtgctgatactgcaggacttggaagaagcata
acctctccaactacattatatgaccggtacagctccccaacagccagcactaccagaaga
cggctatttgttgacaatgacagcccttctgatggagggacacctgggcgcattcctcca
cagcccctcgtcaatgctgtccccgtgcaaaatgtatctggggagccggtttctgtcaca
ccagttcctggacagaccttggtcaccatggcaacagccaccgtcacagccaacaatgga
caaacagtgaccattcctgtacaaggtattgccaatgaaaatggagggataacattcttc
ccagtccaagtcaacgttgggggacaggcacaaactgtggccggctctctccagcctctc
agtgctcaggccctggccggaagtctgagctctcaccaggtgacaggaacaactttgcaa
gttcctggccaggtggccattcagcaaatttccccaggtggacaacccccgaaacaaggc
cagcctttaaccagcagcaatattagacccaggaagaccagttctttatcacttttcttt
agaaaggtttatcatttagcaggtgtccgccttcgagatctttgtgctaaactagatatt
tcagatgaactgaggaaaaaaatctggacctgctttgaattctccataattcaatgtcct
gaacttatgatggacagacatctggaccagctgttaatgtgcgccatttatgtgatggcc
aaggtgacaaaagacgacaggtccttccagaatatcatgcgttgttacaggactcagcca
caggctcggagccaggtatatagaagtgttttgataaaagggaaaagaaaaagaagaaat
tctggcagcagtgatagcagaagccatcagaattccccaacagaactgaacagagacaga
accagtagagactcgagtcctgtcatgaggtcaagcagcacactgcctgtcccacagcct
agcagcgctccccctacacctacccgcctcaccggcgccaacagcgacatggaagaggag
gagaggggcgacctcatccagttctacaacaacgtctacataaagcagattaaaacattt
gccatgaaatactcacaggcaaacgtgatggatgctcctccactgtctccctacccgttt
gtaagaacaggctctcctcgccgaatacagttgtctcaaaatcatcctgtatacatttcc
ccacataaaaatgaaacgatgctttctcctcgagaaaagattttctactacttcagcaac
agcccatcaaagagactgagagaaattaacagtatgatacgaacaggagaaactccaact
aaaaagagaggtattcttctggaagatggaagtgaatcacctgcaaaacgaatttgccca
gaaaatcattctgccttattacgccgtctccaagatgtagctaacgaccgaggttcccac
tga

KEGG   Oryctolagus cuniculus (rabbit): 100342365
Entry
100342365         CDS       T03373                                 
Name
(RefSeq) retinoblastoma-like protein 1 isoform X1
  KO
K04681  retinoblastoma-like protein 1
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04110  Cell cycle
ocu04218  Cellular senescence
ocu04350  TGF-beta signaling pathway
ocu05165  Human papillomavirus infection
ocu05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    100342365
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    100342365
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100342365
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ocu03000]
    100342365
Transcription factors [BR:ocu03000]
 Eukaryotic type
  Other transcription factors
   Pocket domain Rb
    100342365
SSDB
Motif
Pfam: RB_A RB_B DUF3452 Rb_C TFIIB
Other DBs
NCBI-GeneID: 100342365
NCBI-ProteinID: XP_002710823
Ensembl: ENSOCUG00000005804
UniProt: G1SPQ3
LinkDB
Position
4:10699679..10776120
AA seq 1068 aa
MFEDEPHAEGAAVVAAAGAALQALCQELNLDEGSAAEALDDFATIRGNYSLEGEIMHWLA
CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLSQEFRE
RIERLERNFEVSTVIFKKFEPIFLDIFQNPYEELPKLPRSRKQRRIPCSVKDLFNFCWTL
FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRRDLLNPSFKGLPSAFHTADFQ
APEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK
AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTGDTPLGKLTAQANVECNLQQHFE
KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAASEQLTNIFESCI
RNPVENITKIVKGIGETFCQHYTQSTDEQPGSHIDFAINRLKLAEILYYKILETVMVQET
RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV
IRSEEGLSRDMVKHLNSIEEQILESLAWSHSSVLWEALQASANKVPTCEEVIFPNNFETG
NCGNVQGHLPMIPMSPIMHPRVKEVRTDSGNLRRDMQPLSPISVHERYSSPAAGSAKRRL
FGDDSPKEILMDKILTEGTKLKIAPSSSITAENISISPGQTLLTMATATGTGTIAHKVTI
PMHGIANDAGEITLIPISMNTTQESTVESPVSLTAQSLIGASPKQSHLTKAQEVPLAGMS
KPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMRDRHL
DQLLLCAFYVMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVTYHKNING
DFEMADGDLEDATKTPDCSSGPVKEERGDLIKFYNTVYVGRVKSFALKYDLSNKDHMMDV
PPLSPFPHIKQQPGSPRRVSQQHSIYVSPHKNGSGLTPRSALLYRFNGSPSKSLKDINNM
IRQGEQRTKKRAIAIDSEAESPAKRLCQENDDVLLKRLQDVVSERANH
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgttcgaggacgaaccccacgccgagggcgcggcggtggtcgccgcggccggggcggcg
ctgcaggccctgtgccaggagctgaacctggacgaggggagcgcggccgaagccctggac
gacttcgccaccatccggggcaactacagcttagagggagaaattatgcactggttggca
tgttcgctgtatgttgcctgccgcaaaagcattattcctacagttggaaagggtatcatg
gaaggaaactgtgtgtcacttaccagaatactgcgttcagctaaattaagcttaatacag
ttttttagtaaaatgaagaaatggatggacatgtcaaacctgtcacaagaatttcgtgaa
cgtatagaaaggctagagagaaattttgaagtgtctactgtaattttcaaaaaatttgag
ccaatttttttggatatatttcaaaatccatatgaagagctgccaaagttaccacgaagc
aggaaacagaggcggattccttgcagcgttaaggatctctttaatttctgttggacactc
tttgtttataccaagggtaattttcgtatgattggagatgatttagtaaactcttaccat
ttgcttctgtgctgcctggatctgatttttgctaatgccattatgtgcccaaatagacga
gacttgctaaatccatcgttcaaaggcttgccctctgcgttccacactgctgacttccag
gcccccgaggagcctccctgcatcatcgctgtcctgtgtgagctgcacgatggactgcta
gtggaagccaaaggaataaaggagcactactttaagccgtatatttcaaagctctttgat
aggaagattttaaaaggagaatgcctcctggacctttccagttttactgataacagcaaa
gcagttaacaaggaatatgaagagtatgttctaactgttggtgattttgatgagaggatc
tttctgggagcagatgcagaagaggaaattggaacacctcggaaattcactggtgacacc
ccgctagggaaactgacagcacaggctaatgtggagtgtaatcttcaacaacactttgaa
aaaaaaagatcatttgcaccttctaccccactgacaggacggcgatatttacgagaaaaa
gaagcagtcattactcctgttgcttctgctacccaaagtgtgagccgcttacagagcatt
gtagctggactgaaaaatgcagcaagtgaacaacttacaaatatttttgaatcttgtata
cgtaatcctgtggaaaacattacaaaaatagtgaaaggaataggagagactttctgccaa
cactatacccaatcaacagatgaacagccaggatctcacatagactttgctataaacaga
cttaagctggcagaaattttatattacaaaatattagagactgtaatggttcaggaaaca
cgaagacttcatggaatggatatgtctgttcttttagagcaagatatatttcatcgttcc
ttgatggcttgctgtttggaaatagtactgtttgcctatagctcacctcgtacttttcct
tggattattgaagttctcaatttgcagccattttatttttacaaggttattgaagtggtg
atacgctcagaggaagggctctcgagggacatggtaaaacacctgaacagcattgaagaa
cagattttggagagtttggcatggagtcacagttctgtgctgtgggaagctctccaggct
tctgcaaacaaagttcctacctgtgaagaagttatattcccaaataactttgaaacagga
aattgtggcaatgttcagggacatcttcccatgataccaatgtctcctataatgcatcca
agagtcaaggaggttcggactgatagtgggaatcttcgaagagatatgcaaccattgtct
ccgatttctgtccacgaacgctacagttctcctgctgcagggagtgctaagagacgactt
tttggagatgactccccaaaggaaatccttatggataagatcctaacagaaggaaccaaa
ctgaaaattgctccttcttcaagcattacagctgaaaacatatctatttccccgggacag
actcttctgacaatggccacagccacaggaacaggcacaatagcacataaagttacaatt
ccaatgcatggtattgcaaatgatgctggtgagatcacactgatacctatttccatgaac
acaactcaggagtccacagttgagagtcctgtgtcgcttactgctcagtcgttaattggt
gcttctccaaaacagagccatctaactaaagcccaagaagtgcctctggctggaatgagc
aagccaaagagaactgggtccttagcactgttttacagaaaggtctatcatctggcaagt
gtacgcttacgtgatttatgtttgaagctggatgtttcaaatgaattacgaaggaagata
tggacatgttttgaattcactttagttcactgccctgatctaatgagagacaggcatttg
gatcagctcctcctctgtgccttttacgtcatggcaaaggtaacaaaagaagaaagaact
tttcaggaaataatgaaaagttataggaatcagccccaagctaatagtcatgtatacaga
agtgttttgctgaaaagtattccaagagaagttgtgacatatcataaaaacataaatggt
gattttgaaatggcagatggtgacttggaagatgccacaaaaacacctgactgttccagt
ggacctgtgaaagaggaaagaggtgatcttatcaaattttacaataccgtgtatgtagga
agagtgaagtcatttgcactgaaatacgacttgtcaaataaagaccatatgatggatgtg
ccaccactctctccttttcctcatattaagcaacagccaggctcaccacgccgtgtttcc
cagcagcactctatttatgtttccccacacaagaatgggtctggcctcacgccaaggagc
gccctgctctacagattcaacggcagcccttctaagagtttgaaagatatcaacaacatg
ataaggcaaggtgaacagaggaccaagaagcgagcaatagccattgacagtgaggcagaa
tcacctgccaaacgcctctgtcaggaaaatgacgatgttttgcttaaacgactacaggat
gtcgtcagtgagagagcgaatcactga

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