Oryctolagus cuniculus (rabbit): 100340389 Help Entry 100340389         CDS       T03373                                  Symbol MDM2 Name (RefSeq) MDM2 proto-oncogene   KO K06643   E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu01522   Endocrine resistance ocu01524   Platinum drug resistance ocu04068   FoxO signaling pathway ocu04110   Cell cycle ocu04115   p53 signaling pathway ocu04120   Ubiquitin mediated proteolysis ocu04144   Endocytosis ocu04151   PI3K-Akt signaling pathway ocu04218   Cellular senescence ocu04625   C-type lectin receptor signaling pathway ocu04919   Thyroid hormone signaling pathway ocu05163   Human cytomegalovirus infection ocu05165   Human papillomavirus infection ocu05169   Epstein-Barr virus infection ocu05200   Pathways in cancer ocu05202   Transcriptional misregulation in cancer ocu05203   Viral carcinogenesis ocu05205   Proteoglycans in cancer ocu05206   MicroRNAs in cancer ocu05214   Glioma ocu05215   Prostate cancer ocu05218   Melanoma ocu05219   Bladder cancer ocu05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:ocu00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     100340389 (MDM2)  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     100340389 (MDM2)    04151 PI3K-Akt signaling pathway     100340389 (MDM2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     100340389 (MDM2)   09143 Cell growth and death    04110 Cell cycle     100340389 (MDM2)    04115 p53 signaling pathway     100340389 (MDM2)    04218 Cellular senescence     100340389 (MDM2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100340389 (MDM2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     100340389 (MDM2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100340389 (MDM2)    05202 Transcriptional misregulation in cancer     100340389 (MDM2)    05206 MicroRNAs in cancer     100340389 (MDM2)    05205 Proteoglycans in cancer     100340389 (MDM2)    05203 Viral carcinogenesis     100340389 (MDM2)   09162 Cancer: specific types    05214 Glioma     100340389 (MDM2)    05220 Chronic myeloid leukemia     100340389 (MDM2)    05218 Melanoma     100340389 (MDM2)    05219 Bladder cancer     100340389 (MDM2)    05215 Prostate cancer     100340389 (MDM2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     100340389 (MDM2)    05169 Epstein-Barr virus infection     100340389 (MDM2)    05165 Human papillomavirus infection     100340389 (MDM2)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100340389 (MDM2)    01522 Endocrine resistance     100340389 (MDM2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ocu04131]     100340389 (MDM2)    04121 Ubiquitin system [BR:ocu04121]     100340389 (MDM2) Enzymes [BR:ocu01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      100340389 (MDM2) Membrane trafficking [BR:ocu04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     100340389 (MDM2) Ubiquitin system [BR:ocu04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    MDM2/MDM4 proteins     100340389 (MDM2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-C3HC4_3 SWIB zf-RanBP zf-RING_2 zf-FPG_IleRS Motif Other DBs NCBI-GeneID:  100340389 NCBI-ProteinID:  XP_017197461 LinkDB All DBs Position 4:47780978..47813244 Genome browser AA seq 490 aa AA seqDB search MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQEPSDSST SVSENRCHLEGGNDQKDPDQELQEEKPSSSSLVSRPSTSSRRRAISETEENSDELSERQR KRHKSDSISLSFDESLALCVIREICCERSSSSESTETPSNLDLDDGVSEHSGDWLDQDSV SDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLAD YWKCTSCNEMNPPLPPHCNRCWALRENWLPEDKGKDKGGIPEKAKLENSTHAEEGFDVPD CKKTTADDSQEACVEENDDKSTQASQSQESEDFSQPSTSNSIIYSSQEDVKEFEREETQD KEESTESNIPLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQP IQMIVLTYFN NT seq 1473 nt NT seq  +upstreamnt  +downstreamnt atgtgcaataccaacatgtctgtgtctactgacggtgctgtaagcacctcacagattcca gcttcggaacaagagaccctggttagaccaaagccattacttttgaagttgttaaagtct gttggtgcacaaaaagacacttataccatgaaagaggttatattttatcttggccagtac attatgactaaacgattgtatgatgagaagcaacaacatattgtgtattgttcaaatgat cttcttggagatttgtttggagtgccaagcttctctgtgaaagagcacaggaaaatatat acaatgatctacagaaacttggtagtagtcaatcagcaggaaccatcagattcaagtaca tctgtgagtgagaacaggtgtcaccttgaaggtgggaatgatcaaaaggaccctgatcag gagctgcaggaagagaaaccttcgtcttcaagtttggtttctagaccatctacctcatcc agaaggagagcaattagtgagacagaagaaaattcagatgaattatctgaacgccaaaga aagcgccacaaatcagatagtatttccctgtcctttgatgaaagcctggctctgtgtgta ataagggagatatgttgtgaaagaagcagtagcagtgaatcgacagagacgccatcaaac ctggatcttgatgatggtgtaagtgaacattcaggtgactggctggatcaggattcagtt tctgatcagtttagtgtagaatttgaagttgaatctctagattcagaagattatagcctt agtgaagaaggacaagaactctcagatgaagatgatgaggtatatcgagttactgtgtat caggcaggagagagtgatacagattcatttgaagaagatcctgaaatttccttagctgac tattggaagtgtacttcatgcaatgaaatgaatcctccccttccaccacattgcaacaga tgttgggccctccgtgagaattggcttcctgaagataagggaaaagacaaagggggaatc cctgagaaagccaaactagaaaactcgacacacgcggaagaaggctttgatgttcctgat tgtaaaaaaactacagcagatgattcccaagaagcctgtgttgaggaaaatgatgataaa agcacacaagcctctcaatcacaagaaagtgaggacttctctcagccatcaacttctaat agcattatttatagcagccaagaagatgtcaaagagtttgagagggaagaaacacaagac aaagaagaaagtacagaatctaatattccccttaatgccattgaaccttgtgtgatctgc cagggtcgacctaaaaatggttgcattgttcatggcaaaacaggacacctaatgtcatgt ttcacttgtgccaaaaaactaaagaaaaggaataagccctgcccagtatgtagacaacca attcaaatgattgtgctaacttatttcaactaa

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