Oryctolagus cuniculus (rabbit): 100342852
Help
Entry
100342852 CDS
T03373
Name
(RefSeq) RAC-beta serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu01521
EGFR tyrosine kinase inhibitor resistance
ocu01522
Endocrine resistance
ocu01524
Platinum drug resistance
ocu04010
MAPK signaling pathway
ocu04012
ErbB signaling pathway
ocu04014
Ras signaling pathway
ocu04015
Rap1 signaling pathway
ocu04022
cGMP-PKG signaling pathway
ocu04024
cAMP signaling pathway
ocu04062
Chemokine signaling pathway
ocu04066
HIF-1 signaling pathway
ocu04068
FoxO signaling pathway
ocu04071
Sphingolipid signaling pathway
ocu04072
Phospholipase D signaling pathway
ocu04140
Autophagy - animal
ocu04150
mTOR signaling pathway
ocu04151
PI3K-Akt signaling pathway
ocu04152
AMPK signaling pathway
ocu04210
Apoptosis
ocu04211
Longevity regulating pathway
ocu04213
Longevity regulating pathway - multiple species
ocu04218
Cellular senescence
ocu04261
Adrenergic signaling in cardiomyocytes
ocu04370
VEGF signaling pathway
ocu04371
Apelin signaling pathway
ocu04380
Osteoclast differentiation
ocu04510
Focal adhesion
ocu04550
Signaling pathways regulating pluripotency of stem cells
ocu04611
Platelet activation
ocu04613
Neutrophil extracellular trap formation
ocu04620
Toll-like receptor signaling pathway
ocu04625
C-type lectin receptor signaling pathway
ocu04630
JAK-STAT signaling pathway
ocu04660
T cell receptor signaling pathway
ocu04662
B cell receptor signaling pathway
ocu04664
Fc epsilon RI signaling pathway
ocu04666
Fc gamma R-mediated phagocytosis
ocu04668
TNF signaling pathway
ocu04722
Neurotrophin signaling pathway
ocu04725
Cholinergic synapse
ocu04728
Dopaminergic synapse
ocu04810
Regulation of actin cytoskeleton
ocu04910
Insulin signaling pathway
ocu04914
Progesterone-mediated oocyte maturation
ocu04915
Estrogen signaling pathway
ocu04917
Prolactin signaling pathway
ocu04919
Thyroid hormone signaling pathway
ocu04920
Adipocytokine signaling pathway
ocu04922
Glucagon signaling pathway
ocu04923
Regulation of lipolysis in adipocytes
ocu04926
Relaxin signaling pathway
ocu04929
GnRH secretion
ocu04931
Insulin resistance
ocu04932
Non-alcoholic fatty liver disease
ocu04933
AGE-RAGE signaling pathway in diabetic complications
ocu04935
Growth hormone synthesis, secretion and action
ocu04936
Alcoholic liver disease
ocu04973
Carbohydrate digestion and absorption
ocu05010
Alzheimer disease
ocu05017
Spinocerebellar ataxia
ocu05132
Salmonella infection
ocu05135
Yersinia infection
ocu05142
Chagas disease
ocu05145
Toxoplasmosis
ocu05152
Tuberculosis
ocu05160
Hepatitis C
ocu05161
Hepatitis B
ocu05162
Measles
ocu05163
Human cytomegalovirus infection
ocu05164
Influenza A
ocu05165
Human papillomavirus infection
ocu05166
Human T-cell leukemia virus 1 infection
ocu05167
Kaposi sarcoma-associated herpesvirus infection
ocu05168
Herpes simplex virus 1 infection
ocu05169
Epstein-Barr virus infection
ocu05170
Human immunodeficiency virus 1 infection
ocu05200
Pathways in cancer
ocu05205
Proteoglycans in cancer
ocu05207
Chemical carcinogenesis - receptor activation
ocu05208
Chemical carcinogenesis - reactive oxygen species
ocu05210
Colorectal cancer
ocu05211
Renal cell carcinoma
ocu05212
Pancreatic cancer
ocu05213
Endometrial cancer
ocu05214
Glioma
ocu05215
Prostate cancer
ocu05218
Melanoma
ocu05220
Chronic myeloid leukemia
ocu05221
Acute myeloid leukemia
ocu05222
Small cell lung cancer
ocu05223
Non-small cell lung cancer
ocu05224
Breast cancer
ocu05225
Hepatocellular carcinoma
ocu05226
Gastric cancer
ocu05230
Central carbon metabolism in cancer
ocu05231
Choline metabolism in cancer
ocu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ocu05415
Diabetic cardiomyopathy
ocu05417
Lipid and atherosclerosis
ocu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100342852
04015 Rap1 signaling pathway
100342852
04630 JAK-STAT signaling pathway
100342852
04668 TNF signaling pathway
100342852
04066 HIF-1 signaling pathway
100342852
04068 FoxO signaling pathway
100342852
04072 Phospholipase D signaling pathway
100342852
04071 Sphingolipid signaling pathway
100342852
04024 cAMP signaling pathway
100342852
04022 cGMP-PKG signaling pathway
100342852
04151 PI3K-Akt signaling pathway
100342852
04152 AMPK signaling pathway
100342852
04150 mTOR signaling pathway
100342852
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100342852
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100342852
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100342852
04613 Neutrophil extracellular trap formation
100342852
04620 Toll-like receptor signaling pathway
100342852
04660 T cell receptor signaling pathway
100342852
04662 B cell receptor signaling pathway
100342852
04664 Fc epsilon RI signaling pathway
100342852
04666 Fc gamma R-mediated phagocytosis
100342852
04062 Chemokine signaling pathway
100342852
09152 Endocrine system
04922 Glucagon signaling pathway
100342852
04923 Regulation of lipolysis in adipocytes
100342852
04929 GnRH secretion
100342852
04915 Estrogen signaling pathway
100342852
04917 Prolactin signaling pathway
100342852
04926 Relaxin signaling pathway
100342852
04935 Growth hormone synthesis, secretion and action
100342852
04919 Thyroid hormone signaling pathway
100342852
09154 Digestive system
04973 Carbohydrate digestion and absorption
100342852
09156 Nervous system
04725 Cholinergic synapse
100342852
04728 Dopaminergic synapse
100342852
04722 Neurotrophin signaling pathway
100342852
09158 Development and regeneration
04380 Osteoclast differentiation
100342852
09149 Aging
04211 Longevity regulating pathway
100342852
04213 Longevity regulating pathway - multiple species
100342852
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100342852
05205 Proteoglycans in cancer
100342852
05207 Chemical carcinogenesis - receptor activation
100342852
05208 Chemical carcinogenesis - reactive oxygen species
100342852
05230 Central carbon metabolism in cancer
100342852
05231 Choline metabolism in cancer
100342852
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100342852
09162 Cancer: specific types
05210 Colorectal cancer
100342852
05212 Pancreatic cancer
100342852
05225 Hepatocellular carcinoma
100342852
05226 Gastric cancer
100342852
05214 Glioma
100342852
05221 Acute myeloid leukemia
100342852
05220 Chronic myeloid leukemia
100342852
05218 Melanoma
100342852
05211 Renal cell carcinoma
100342852
05215 Prostate cancer
100342852
05213 Endometrial cancer
100342852
05224 Breast cancer
100342852
05222 Small cell lung cancer
100342852
05223 Non-small cell lung cancer
100342852
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100342852
05170 Human immunodeficiency virus 1 infection
100342852
05161 Hepatitis B
100342852
05160 Hepatitis C
100342852
05164 Influenza A
100342852
05162 Measles
100342852
05163 Human cytomegalovirus infection
100342852
05167 Kaposi sarcoma-associated herpesvirus infection
100342852
05169 Epstein-Barr virus infection
100342852
05165 Human papillomavirus infection
100342852
09171 Infectious disease: bacterial
05135 Yersinia infection
100342852
05152 Tuberculosis
100342852
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100342852
05142 Chagas disease
100342852
09164 Neurodegenerative disease
05010 Alzheimer disease
100342852
05017 Spinocerebellar ataxia
100342852
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100342852
05418 Fluid shear stress and atherosclerosis
100342852
05415 Diabetic cardiomyopathy
100342852
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100342852
04932 Non-alcoholic fatty liver disease
100342852
04931 Insulin resistance
100342852
04933 AGE-RAGE signaling pathway in diabetic complications
100342852
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100342852
01524 Platinum drug resistance
100342852
01522 Endocrine resistance
100342852
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocu01001
]
100342852
Enzymes [BR:
ocu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100342852
Protein kinases [BR:
ocu01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100342852
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_20
PH_11
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
100342852
NCBI-ProteinID:
XP_051692350
LinkDB
All DBs
Position
Unknown
AA seq
481 aa
AA seq
DB search
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGEDPM
DYKCGSPSDSSAAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSVDWQDVVHR
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaacgaggtgtctgtcatcaaagaaggctggctccacaagcgcggtgaatacatcaag
acctggaggccccggtacttcctgctcaagagtgacggctccttcattgggtacaaggag
aggcccgaggcccccgaccagaccttaccccccttaaacaacttctccgtagcagaatgc
cagctgatgaagaccgagaggccacggcccaacaccttcgtcatccgctgcctgcagtgg
accacggtcattgagaggactttccacgtggactccccagacgagcgggaggagtggatg
cgggccatccagatggtcgccaacagcctcaagcagcggggcccgggcgaggaccccatg
gactacaagtgtggctcccccagcgactcctccgctgctgaggagatggaagtggcggtc
agcaaggctcgggccaaggtgaccatgaacgacttcgactatctcaaactcctgggcaag
ggcaccttcggcaaagtcatcctggtgcgggagaaggccaccggccgctactacgccatg
aagatcctgcggaaagaggtcatcatcgccaaggatgaagtcgcccacacggtgaccgag
agccgcgtcctccagaacaccaggcacccgttcctcacagcgctgaagtacgcattccag
acccatgaccgcctgtgtttcgtgatggagtacgccaatggcggagagctgttcttccac
ctgtcccgggagcgcgtcttcacggaggagcgggcgcggttctacggtgcggaaatcgtc
tcggctctcgagtacctgcactcgcgggatgtggtctaccgcgacatcaagctggaaaac
ctcatgctggacaaagacggccacatcaagatcactgacttcggcctgtgcaaagagggc
atcagcgacggggccaccatgaagaccttctgtgggacgccggagtacctggcacccgag
gtgctggaggacaacgactatggcagggccgtggactggtgggggctgggcgtggtcatg
tacgagatgatgtgcggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag
ctcatcctcatggaggagatccgcttcccgcgcacgctcagcccggaggccaagtccctg
ctcgccgggctgctcaagaaggaccccaagcagaggctcggtggggggcccagtgacgcc
aaggaggtcatggagcacaggttcttcctcagcgtcgactggcaggacgtggtgcacagg
aagctcctgccgcccttcaagccccaggtcacctccgaggtcgacacgcggtacttcgac
gacgagttcaccgcgcagtccatcacaatcacaccccccgaccgctatgacagcctgggc
tcgctggagctggaccagcggacgcacttcccccagttctcctactcggccagcatccgc
gagtga
Oryctolagus cuniculus (rabbit): 100353706
Help
Entry
100353706 CDS
T03373
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu01521
EGFR tyrosine kinase inhibitor resistance
ocu01522
Endocrine resistance
ocu01524
Platinum drug resistance
ocu04010
MAPK signaling pathway
ocu04012
ErbB signaling pathway
ocu04014
Ras signaling pathway
ocu04015
Rap1 signaling pathway
ocu04022
cGMP-PKG signaling pathway
ocu04024
cAMP signaling pathway
ocu04062
Chemokine signaling pathway
ocu04066
HIF-1 signaling pathway
ocu04068
FoxO signaling pathway
ocu04071
Sphingolipid signaling pathway
ocu04072
Phospholipase D signaling pathway
ocu04140
Autophagy - animal
ocu04150
mTOR signaling pathway
ocu04151
PI3K-Akt signaling pathway
ocu04152
AMPK signaling pathway
ocu04210
Apoptosis
ocu04211
Longevity regulating pathway
ocu04213
Longevity regulating pathway - multiple species
ocu04218
Cellular senescence
ocu04261
Adrenergic signaling in cardiomyocytes
ocu04370
VEGF signaling pathway
ocu04371
Apelin signaling pathway
ocu04380
Osteoclast differentiation
ocu04510
Focal adhesion
ocu04550
Signaling pathways regulating pluripotency of stem cells
ocu04611
Platelet activation
ocu04613
Neutrophil extracellular trap formation
ocu04620
Toll-like receptor signaling pathway
ocu04625
C-type lectin receptor signaling pathway
ocu04630
JAK-STAT signaling pathway
ocu04660
T cell receptor signaling pathway
ocu04662
B cell receptor signaling pathway
ocu04664
Fc epsilon RI signaling pathway
ocu04666
Fc gamma R-mediated phagocytosis
ocu04668
TNF signaling pathway
ocu04722
Neurotrophin signaling pathway
ocu04725
Cholinergic synapse
ocu04728
Dopaminergic synapse
ocu04810
Regulation of actin cytoskeleton
ocu04910
Insulin signaling pathway
ocu04914
Progesterone-mediated oocyte maturation
ocu04915
Estrogen signaling pathway
ocu04917
Prolactin signaling pathway
ocu04919
Thyroid hormone signaling pathway
ocu04920
Adipocytokine signaling pathway
ocu04922
Glucagon signaling pathway
ocu04923
Regulation of lipolysis in adipocytes
ocu04926
Relaxin signaling pathway
ocu04929
GnRH secretion
ocu04931
Insulin resistance
ocu04932
Non-alcoholic fatty liver disease
ocu04933
AGE-RAGE signaling pathway in diabetic complications
ocu04935
Growth hormone synthesis, secretion and action
ocu04936
Alcoholic liver disease
ocu04973
Carbohydrate digestion and absorption
ocu05010
Alzheimer disease
ocu05017
Spinocerebellar ataxia
ocu05132
Salmonella infection
ocu05135
Yersinia infection
ocu05142
Chagas disease
ocu05145
Toxoplasmosis
ocu05152
Tuberculosis
ocu05160
Hepatitis C
ocu05161
Hepatitis B
ocu05162
Measles
ocu05163
Human cytomegalovirus infection
ocu05164
Influenza A
ocu05165
Human papillomavirus infection
ocu05166
Human T-cell leukemia virus 1 infection
ocu05167
Kaposi sarcoma-associated herpesvirus infection
ocu05168
Herpes simplex virus 1 infection
ocu05169
Epstein-Barr virus infection
ocu05170
Human immunodeficiency virus 1 infection
ocu05200
Pathways in cancer
ocu05205
Proteoglycans in cancer
ocu05207
Chemical carcinogenesis - receptor activation
ocu05208
Chemical carcinogenesis - reactive oxygen species
ocu05210
Colorectal cancer
ocu05211
Renal cell carcinoma
ocu05212
Pancreatic cancer
ocu05213
Endometrial cancer
ocu05214
Glioma
ocu05215
Prostate cancer
ocu05218
Melanoma
ocu05220
Chronic myeloid leukemia
ocu05221
Acute myeloid leukemia
ocu05222
Small cell lung cancer
ocu05223
Non-small cell lung cancer
ocu05224
Breast cancer
ocu05225
Hepatocellular carcinoma
ocu05226
Gastric cancer
ocu05230
Central carbon metabolism in cancer
ocu05231
Choline metabolism in cancer
ocu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ocu05415
Diabetic cardiomyopathy
ocu05417
Lipid and atherosclerosis
ocu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100353706
04015 Rap1 signaling pathway
100353706
04630 JAK-STAT signaling pathway
100353706
04668 TNF signaling pathway
100353706
04066 HIF-1 signaling pathway
100353706
04068 FoxO signaling pathway
100353706
04072 Phospholipase D signaling pathway
100353706
04071 Sphingolipid signaling pathway
100353706
04024 cAMP signaling pathway
100353706
04022 cGMP-PKG signaling pathway
100353706
04151 PI3K-Akt signaling pathway
100353706
04152 AMPK signaling pathway
100353706
04150 mTOR signaling pathway
100353706
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100353706
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100353706
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100353706
04613 Neutrophil extracellular trap formation
100353706
04620 Toll-like receptor signaling pathway
100353706
04660 T cell receptor signaling pathway
100353706
04662 B cell receptor signaling pathway
100353706
04664 Fc epsilon RI signaling pathway
100353706
04666 Fc gamma R-mediated phagocytosis
100353706
04062 Chemokine signaling pathway
100353706
09152 Endocrine system
04922 Glucagon signaling pathway
100353706
04923 Regulation of lipolysis in adipocytes
100353706
04929 GnRH secretion
100353706
04915 Estrogen signaling pathway
100353706
04917 Prolactin signaling pathway
100353706
04926 Relaxin signaling pathway
100353706
04935 Growth hormone synthesis, secretion and action
100353706
04919 Thyroid hormone signaling pathway
100353706
09154 Digestive system
04973 Carbohydrate digestion and absorption
100353706
09156 Nervous system
04725 Cholinergic synapse
100353706
04728 Dopaminergic synapse
100353706
04722 Neurotrophin signaling pathway
100353706
09158 Development and regeneration
04380 Osteoclast differentiation
100353706
09149 Aging
04211 Longevity regulating pathway
100353706
04213 Longevity regulating pathway - multiple species
100353706
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100353706
05205 Proteoglycans in cancer
100353706
05207 Chemical carcinogenesis - receptor activation
100353706
05208 Chemical carcinogenesis - reactive oxygen species
100353706
05230 Central carbon metabolism in cancer
100353706
05231 Choline metabolism in cancer
100353706
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100353706
09162 Cancer: specific types
05210 Colorectal cancer
100353706
05212 Pancreatic cancer
100353706
05225 Hepatocellular carcinoma
100353706
05226 Gastric cancer
100353706
05214 Glioma
100353706
05221 Acute myeloid leukemia
100353706
05220 Chronic myeloid leukemia
100353706
05218 Melanoma
100353706
05211 Renal cell carcinoma
100353706
05215 Prostate cancer
100353706
05213 Endometrial cancer
100353706
05224 Breast cancer
100353706
05222 Small cell lung cancer
100353706
05223 Non-small cell lung cancer
100353706
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100353706
05170 Human immunodeficiency virus 1 infection
100353706
05161 Hepatitis B
100353706
05160 Hepatitis C
100353706
05164 Influenza A
100353706
05162 Measles
100353706
05163 Human cytomegalovirus infection
100353706
05167 Kaposi sarcoma-associated herpesvirus infection
100353706
05169 Epstein-Barr virus infection
100353706
05165 Human papillomavirus infection
100353706
09171 Infectious disease: bacterial
05135 Yersinia infection
100353706
05152 Tuberculosis
100353706
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100353706
05142 Chagas disease
100353706
09164 Neurodegenerative disease
05010 Alzheimer disease
100353706
05017 Spinocerebellar ataxia
100353706
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100353706
05418 Fluid shear stress and atherosclerosis
100353706
05415 Diabetic cardiomyopathy
100353706
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100353706
04932 Non-alcoholic fatty liver disease
100353706
04931 Insulin resistance
100353706
04933 AGE-RAGE signaling pathway in diabetic complications
100353706
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100353706
01524 Platinum drug resistance
100353706
01522 Endocrine resistance
100353706
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocu01001
]
100353706
Enzymes [BR:
ocu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100353706
Protein kinases [BR:
ocu01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100353706
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_20
ABC1
PH_11
Motif
Other DBs
NCBI-GeneID:
100353706
NCBI-ProteinID:
XP_051676760
Ensembl:
ENSOCUG00000015901
LinkDB
All DBs
Position
16:complement(61445896..61751067)
Genome browser
AA seq
479 aa
AA seq
DB search
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGINWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccacgatacttccttttgaagacagatggctcattcataggatataaagag
aaacctcaagatgtggatttaccttaccccctcaacaacttttcagtggcaaagtgccag
ttaatgaaaacagaacgaccaaagccaaacacatttattatcagatgtctccagtggacc
actgtcatagagagaacatttcatgtagatactccagaagaaagggaagaatggacagaa
gctatccaggctgtagcagacagactgcaaaggcaagaagaggagagaatgaattgtagt
ccaacttcacaaattgataatataggggaggaagagatggatgcttctacaactcatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg
aaagtcattttggttcgagagaaggcaagtgggaaatattatgctatgaagattctgaag
aaagaagtcattattgcaaaggatgaagtggcacacactttaacggaaagcagagtatta
aagaacactagacatccctttttaacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatggtggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggcaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggatcacagatgca
gccaccatgaagacattttgtggcacaccagaatatctggcaccagaggtgttagaagac
aatgactatggccgagcagtagactggtggggtctcggggttgtcatgtatgaaatgatg
tgtgggaggttgccgttctacaaccaggaccatgagaaactttttgaactgatactaatg
gaagacattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggaggaccagacgatgcaaaagaaattatg
agacatagtttcttttctggaataaactggcaagatgtatatgataaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagataccagatactttgatgaagaatttaca
gctcagactattacaataacgccacctgagaaatatgatgaggatggtatggactgcatg
gacaatgagaggcggccgcatttccctcagttttcctactctgcaagtggacgggaataa
Oryctolagus cuniculus (rabbit): 127486116
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Entry
127486116 CDS
T03373
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase isoform X1
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu01521
EGFR tyrosine kinase inhibitor resistance
ocu01522
Endocrine resistance
ocu01524
Platinum drug resistance
ocu04010
MAPK signaling pathway
ocu04012
ErbB signaling pathway
ocu04014
Ras signaling pathway
ocu04015
Rap1 signaling pathway
ocu04022
cGMP-PKG signaling pathway
ocu04024
cAMP signaling pathway
ocu04062
Chemokine signaling pathway
ocu04066
HIF-1 signaling pathway
ocu04068
FoxO signaling pathway
ocu04071
Sphingolipid signaling pathway
ocu04072
Phospholipase D signaling pathway
ocu04140
Autophagy - animal
ocu04150
mTOR signaling pathway
ocu04151
PI3K-Akt signaling pathway
ocu04152
AMPK signaling pathway
ocu04210
Apoptosis
ocu04211
Longevity regulating pathway
ocu04213
Longevity regulating pathway - multiple species
ocu04218
Cellular senescence
ocu04261
Adrenergic signaling in cardiomyocytes
ocu04370
VEGF signaling pathway
ocu04371
Apelin signaling pathway
ocu04380
Osteoclast differentiation
ocu04510
Focal adhesion
ocu04550
Signaling pathways regulating pluripotency of stem cells
ocu04611
Platelet activation
ocu04613
Neutrophil extracellular trap formation
ocu04620
Toll-like receptor signaling pathway
ocu04625
C-type lectin receptor signaling pathway
ocu04630
JAK-STAT signaling pathway
ocu04660
T cell receptor signaling pathway
ocu04662
B cell receptor signaling pathway
ocu04664
Fc epsilon RI signaling pathway
ocu04666
Fc gamma R-mediated phagocytosis
ocu04668
TNF signaling pathway
ocu04722
Neurotrophin signaling pathway
ocu04725
Cholinergic synapse
ocu04728
Dopaminergic synapse
ocu04810
Regulation of actin cytoskeleton
ocu04910
Insulin signaling pathway
ocu04914
Progesterone-mediated oocyte maturation
ocu04915
Estrogen signaling pathway
ocu04917
Prolactin signaling pathway
ocu04919
Thyroid hormone signaling pathway
ocu04920
Adipocytokine signaling pathway
ocu04922
Glucagon signaling pathway
ocu04923
Regulation of lipolysis in adipocytes
ocu04926
Relaxin signaling pathway
ocu04929
GnRH secretion
ocu04931
Insulin resistance
ocu04932
Non-alcoholic fatty liver disease
ocu04933
AGE-RAGE signaling pathway in diabetic complications
ocu04935
Growth hormone synthesis, secretion and action
ocu04936
Alcoholic liver disease
ocu04973
Carbohydrate digestion and absorption
ocu05010
Alzheimer disease
ocu05017
Spinocerebellar ataxia
ocu05132
Salmonella infection
ocu05135
Yersinia infection
ocu05142
Chagas disease
ocu05145
Toxoplasmosis
ocu05152
Tuberculosis
ocu05160
Hepatitis C
ocu05161
Hepatitis B
ocu05162
Measles
ocu05163
Human cytomegalovirus infection
ocu05164
Influenza A
ocu05165
Human papillomavirus infection
ocu05166
Human T-cell leukemia virus 1 infection
ocu05167
Kaposi sarcoma-associated herpesvirus infection
ocu05168
Herpes simplex virus 1 infection
ocu05169
Epstein-Barr virus infection
ocu05170
Human immunodeficiency virus 1 infection
ocu05200
Pathways in cancer
ocu05205
Proteoglycans in cancer
ocu05207
Chemical carcinogenesis - receptor activation
ocu05208
Chemical carcinogenesis - reactive oxygen species
ocu05210
Colorectal cancer
ocu05211
Renal cell carcinoma
ocu05212
Pancreatic cancer
ocu05213
Endometrial cancer
ocu05214
Glioma
ocu05215
Prostate cancer
ocu05218
Melanoma
ocu05220
Chronic myeloid leukemia
ocu05221
Acute myeloid leukemia
ocu05222
Small cell lung cancer
ocu05223
Non-small cell lung cancer
ocu05224
Breast cancer
ocu05225
Hepatocellular carcinoma
ocu05226
Gastric cancer
ocu05230
Central carbon metabolism in cancer
ocu05231
Choline metabolism in cancer
ocu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ocu05415
Diabetic cardiomyopathy
ocu05417
Lipid and atherosclerosis
ocu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
127486116
04015 Rap1 signaling pathway
127486116
04630 JAK-STAT signaling pathway
127486116
04668 TNF signaling pathway
127486116
04066 HIF-1 signaling pathway
127486116
04068 FoxO signaling pathway
127486116
04072 Phospholipase D signaling pathway
127486116
04071 Sphingolipid signaling pathway
127486116
04024 cAMP signaling pathway
127486116
04022 cGMP-PKG signaling pathway
127486116
04151 PI3K-Akt signaling pathway
127486116
04152 AMPK signaling pathway
127486116
04150 mTOR signaling pathway
127486116
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
127486116
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
127486116
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
127486116
04613 Neutrophil extracellular trap formation
127486116
04620 Toll-like receptor signaling pathway
127486116
04660 T cell receptor signaling pathway
127486116
04662 B cell receptor signaling pathway
127486116
04664 Fc epsilon RI signaling pathway
127486116
04666 Fc gamma R-mediated phagocytosis
127486116
04062 Chemokine signaling pathway
127486116
09152 Endocrine system
04922 Glucagon signaling pathway
127486116
04923 Regulation of lipolysis in adipocytes
127486116
04929 GnRH secretion
127486116
04915 Estrogen signaling pathway
127486116
04917 Prolactin signaling pathway
127486116
04926 Relaxin signaling pathway
127486116
04935 Growth hormone synthesis, secretion and action
127486116
04919 Thyroid hormone signaling pathway
127486116
09154 Digestive system
04973 Carbohydrate digestion and absorption
127486116
09156 Nervous system
04725 Cholinergic synapse
127486116
04728 Dopaminergic synapse
127486116
04722 Neurotrophin signaling pathway
127486116
09158 Development and regeneration
04380 Osteoclast differentiation
127486116
09149 Aging
04211 Longevity regulating pathway
127486116
04213 Longevity regulating pathway - multiple species
127486116
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
127486116
05205 Proteoglycans in cancer
127486116
05207 Chemical carcinogenesis - receptor activation
127486116
05208 Chemical carcinogenesis - reactive oxygen species
127486116
05230 Central carbon metabolism in cancer
127486116
05231 Choline metabolism in cancer
127486116
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
127486116
09162 Cancer: specific types
05210 Colorectal cancer
127486116
05212 Pancreatic cancer
127486116
05225 Hepatocellular carcinoma
127486116
05226 Gastric cancer
127486116
05214 Glioma
127486116
05221 Acute myeloid leukemia
127486116
05220 Chronic myeloid leukemia
127486116
05218 Melanoma
127486116
05211 Renal cell carcinoma
127486116
05215 Prostate cancer
127486116
05213 Endometrial cancer
127486116
05224 Breast cancer
127486116
05222 Small cell lung cancer
127486116
05223 Non-small cell lung cancer
127486116
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
127486116
05170 Human immunodeficiency virus 1 infection
127486116
05161 Hepatitis B
127486116
05160 Hepatitis C
127486116
05164 Influenza A
127486116
05162 Measles
127486116
05163 Human cytomegalovirus infection
127486116
05167 Kaposi sarcoma-associated herpesvirus infection
127486116
05169 Epstein-Barr virus infection
127486116
05165 Human papillomavirus infection
127486116
09171 Infectious disease: bacterial
05135 Yersinia infection
127486116
05152 Tuberculosis
127486116
09174 Infectious disease: parasitic
05145 Toxoplasmosis
127486116
05142 Chagas disease
127486116
09164 Neurodegenerative disease
05010 Alzheimer disease
127486116
05017 Spinocerebellar ataxia
127486116
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
127486116
05418 Fluid shear stress and atherosclerosis
127486116
05415 Diabetic cardiomyopathy
127486116
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
127486116
04932 Non-alcoholic fatty liver disease
127486116
04931 Insulin resistance
127486116
04933 AGE-RAGE signaling pathway in diabetic complications
127486116
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
127486116
01524 Platinum drug resistance
127486116
01522 Endocrine resistance
127486116
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocu01001
]
127486116
Enzymes [BR:
ocu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
127486116
Protein kinases [BR:
ocu01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
127486116
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_20
PH_11
Motif
Other DBs
NCBI-GeneID:
127486116
NCBI-ProteinID:
XP_051685791
LinkDB
All DBs
Position
Unknown
AA seq
487 aa
AA seq
DB search
MNAVSIVKEGWLHKRGEYIKTWRPRYFLLKTDGTFIGYKERPQDVEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEDTMDF
RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEERARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIRITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKALLAGLLKKDPKQRLGGGSEDAKEIMRHRFFSGIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQVPCPCPADDSMECVDSERRPHFPQFS
YSASGTA
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgaacgccgtgagcatcgtgaaggagggctggctgcacaagcgaggggagtacatcaag
acctggcggccacgctacttcctcctcaagactgatggcaccttcatcggctacaaggag
cggccacaggacgtggagcagcgcgagtccccactcaacaacttctctgtggcacaatgc
cagctgatgaagacggagcggccgcggcccaacaccttcatcatccgctgcctgcagtgg
accacggtcatcgagcgcaccttccacgtggagacccccgaggagcgggaggagtggacg
actgccatccagacggtggccgacgggctcaagaagcaggaggaggacacgatggacttc
cggtcagggtctcccagtgacaactcgggggccgaggagatggaggtgtccctggccaag
cccaagcatcgtgtgaccatgaacgagtttgagtacctgaagctgctgggcaagggcacc
tttgggaaggtgatcctggtgaaggagaaggccacgggccgctactacgccatgaagatc
ctgaagaaagaggtcatcgtggccaaggatgaggtggcgcacacgctcacggagaaccgc
gtgctgcagaactccaggcaccccttcctcacggccctcaagtactctttccagacgcat
gaccgcctctgctttgtcatggagtacgccaacgggggcgagctcttcttccacctgtcc
cgcgagcgcgtcttctccgaggagcgggcccgcttctacggcgccgagatcgtgtcggcg
ctggactacctgcactcggagaagaacgtggtgtaccgcgacctcaagctggagaacctc
atgctggacaaggacgggcacatcaggatcacggacttcgggctgtgcaaggagggcatc
aaggacggcgccaccatgaagaccttctgcgggacgcccgagtacctggcccctgaggtg
ctggaggacaacgactacggccgggcggtggactggtgggggctgggcgtggtcatgtac
gagatgatgtgcggccgcctgcccttctacaaccaggaccacgagaagctgttcgagctc
atcctcatggaggagatccgcttcccgcgcacgctgggccccgaggccaaggccctgctc
gccgggctgctcaagaaggaccccaagcagcggctcggcgggggctccgaggacgccaag
gagatcatgcggcaccgcttcttctccggcatcgtgtggcaggacgtgtatgagaagaag
ctgagcccgcccttcaagcctcaagtcacctccgagacggacaccaggtattttgacgag
gagttcacggcccagatgatcaccatcacgccgcctgaccaagtgccctgtccctgcccc
gcagatgacagcatggagtgcgtggacagcgagcgcaggccgcacttcccccagttctcc
tactcggccagcggcacggcctga
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integrated database retrieval system