KEGG   Oryctolagus cuniculus (rabbit): 100343571
Entry
100343571         CDS       T03373                                 
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 7 isoform X1
  KO
K04427  mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04064  NF-kappa B signaling pathway
ocu04140  Autophagy - animal
ocu04152  AMPK signaling pathway
ocu04310  Wnt signaling pathway
ocu04380  Osteoclast differentiation
ocu04520  Adherens junction
ocu04613  Neutrophil extracellular trap formation
ocu04620  Toll-like receptor signaling pathway
ocu04621  NOD-like receptor signaling pathway
ocu04622  RIG-I-like receptor signaling pathway
ocu04657  IL-17 signaling pathway
ocu04660  T cell receptor signaling pathway
ocu04668  TNF signaling pathway
ocu04936  Alcoholic liver disease
ocu05132  Salmonella infection
ocu05135  Yersinia infection
ocu05140  Leishmaniasis
ocu05145  Toxoplasmosis
ocu05161  Hepatitis B
ocu05162  Measles
ocu05168  Herpes simplex virus 1 infection
ocu05169  Epstein-Barr virus infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05171  Coronavirus disease - COVID-19
ocu05417  Lipid and atherosclerosis
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    100343571
   04064 NF-kappa B signaling pathway
    100343571
   04668 TNF signaling pathway
    100343571
   04152 AMPK signaling pathway
    100343571
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100343571
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100343571
   04620 Toll-like receptor signaling pathway
    100343571
   04660 T cell receptor signaling pathway
    100343571
   04657 IL-17 signaling pathway
    100343571
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100343571
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100343571
   05161 Hepatitis B
    100343571
   05171 Coronavirus disease - COVID-19
    100343571
   05162 Measles
    100343571
   05169 Epstein-Barr virus infection
    100343571
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100343571
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100343571
   05140 Leishmaniasis
    100343571
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100343571
   05418 Fluid shear stress and atherosclerosis
    100343571
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100343571
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100343571
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     100343571
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: TKL group
  MLK family
   100343571
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase APH DUF3939
Other DBs
NCBI-GeneID: 100343571
NCBI-ProteinID: XP_002714630
Ensembl: ENSOCUG00000001698
UniProt: G1SFY3
LinkDB
Position
12:78385962..78464574
AA seq 606 aa
MSTASAASSSSSSSTSEMIEAPTQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNVEQVSATNDTIKRLESKLLKNQAKQQ
SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATAAYSKPKRGHRKTASFGN
ILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPARSHP
WTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEI
ALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQ
KRQGTS
NT seq 1821 nt   +upstreamnt  +downstreamnt
atgtctacagcctctgccgcctcctcctcctcttcgtcttcgaccagtgagatgatcgaa
gcccctacccaggtccttaactttgaggagatcgactacaaggagatcgaggtggaagag
gttgttggaagaggagcctttggagtggtttgcaaagctaaatggagagcaaaagatgtt
gctattaaacaaatagaaagtgaatctgagaggaaagcatttattgtggagcttcggcag
ttgtctcgggtgaaccatcccaatattgtaaagctatatggagcctgcttaaatccagta
tgtcttgtgatggaatatgctgaagggggctctttatataatgtgctgcatggtgctgaa
ccattgccttattatactgctgcccacgcaatgagttggtgtttacagtgttcccaagga
gtggcttaccttcacagcatgcaacccaaagctctaattcacagggacctgaaaccacca
aatttgctgctggttgcaggggggactgttctaaaaatctgtgattttggtacagcctgt
gacattcagacacacatgaccaataacaaggggagtgctgcatggatggcacctgaagtt
tttgaaggtagcaattacagtgaaaaatgtgacgtcttcagctggggcattatcctttgg
gaagtgataacacgtcggaaaccttttgatgaaattggtgggccggctttccgaatcatg
tgggctgttcataatggtactcgaccaccactgatcaaaaatttacctaagcccattgag
agcctgatgactcgttgttggtctaaagacccttctcagcgcccttccatggaggaaatt
gtgaaaataatgactcacttgatgcggtacttcccaggagcagatgagccattgcagtat
ccttgtcagtattcagatgaaggacagagtaattctgccaccagtacaggttcattcatg
gatatcgcttctacaaataccagtaataaaagtgacactaacgtggaacaagtttctgcc
acaaatgatactattaaacgcctagaatctaaattgttgaaaaatcaagccaagcaacag
agtgaatccggacgtttgagcttgggagcctcccgtggaagcagtgtggaaagcttgccc
ccaacctctgagggcaaaaggatgagtgctgacatgtctgaaatagaagctaggattgct
gcgaccgcagcatattccaagcctaaacgaggccaccgtaaaactgcttcatttggcaac
attctggatgtccctgagatcgtcatatcaggcaacggacagccaagacgtagatccatt
caagacttgactgttactggaacagaacctggtcaggtgagcagtaggtcatccagtcct
agtgtcagaatgatcactacctcaggaccaacctcagaaaagccggctcgaagtcatcca
tggacccctgatgattccacagataccaatggatcagataactccatccctatggcctat
cttacactggatcaccaactacagcctctagcaccatgcccaaactccaaagaatctatg
gcagtgtttgaacaacattgtaaaatggcacaagaatatatgaaagttcaaacagaaatt
gcattgttattacagagaaagcaggaactagttgcagaattggaccaggatgaaaaggac
cagcaaaatacatctcgactggtacaggaacataaaaagcttttagatgaaaacaaaagc
ctttctacttactaccagcaatgcaaaaaacagctagaggtcatcagaagtcagcagcaa
aaacgacaaggcacttcatga

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