KEGG   Oryctolagus cuniculus (rabbit): 100348648
Entry
100348648         CDS       T03373                                 
Symbol
PTPN6
Name
(RefSeq) protein tyrosine phosphatase, non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04520  Adherens junction
ocu04630  JAK-STAT signaling pathway
ocu04650  Natural killer cell mediated cytotoxicity
ocu04660  T cell receptor signaling pathway
ocu04662  B cell receptor signaling pathway
ocu05140  Leishmaniasis
ocu05205  Proteoglycans in cancer
ocu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100348648 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100348648 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100348648 (PTPN6)
   04660 T cell receptor signaling pathway
    100348648 (PTPN6)
   04662 B cell receptor signaling pathway
    100348648 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100348648 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100348648 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    100348648 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ocu01009]
    100348648 (PTPN6)
Enzymes [BR:ocu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     100348648 (PTPN6)
Protein phosphatases and associated proteins [BR:ocu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    100348648 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase PolyA_pol_arg_C
Other DBs
NCBI-GeneID: 100348648
NCBI-ProteinID: XP_008257988
Ensembl: ENSOCUG00000003599
LinkDB
Position
8:32944741..32964164
AA seq 566 aa
MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQLKSGPGSPLRVTHIKVMCEGGRYTV
GGPDTFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIESRVLELNKKKESED
SAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPG
SDYINANYVKNQLLGPDENTKTYIASQGCLEATVNDFWQMAWQENTRVIVMTTREVEKGR
NKCVPYWPELGTQRVYGLYSVSNCREHDTAEYKLRTLQVSPLDNGNLVREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGQESEYGN
ITYPPAMKNAHAKASRTSSKHKEGCV
NT seq 1701 nt   +upstreamnt  +downstreamnt
atgctgtcccgtgggtggttccaccgggacctcagtgggctggacgcagagaccctgctc
aagggccgaggcgtccatggcagcttcctggctcggcccagtcgcaagaaccagggagac
ttctccctgtctgtcagggtcggggaccaggtgacccacattcggatccagaactctggg
gatttctacgacctgtatggaggggagaagttcgccacgctgacggagctggtggagtac
tacacacagcagcagggcgtgctgcaggaccgtgacggcaccatcatccacctcaagtac
ccgctcaactgctccgaccccactagcgagagatggtaccacggccacatgtctggaggg
caggcagagacgctgctgcaggccaagggcgagccctggacgtttctggtgcgtgagagt
ctcagccagcctggagattttgtgctgtcggtgctcagcgaccagctcaagagtggccct
ggctccccgctcagggtcacccacatcaaggtcatgtgcgagggtggacgctacacggtg
ggcggtcccgacacctttgacagcctcacggacctggtggagcatttcaagaagacgggg
attgaggaggcctctggcgccttcgtctatctgcggcagccatactacgccacacgggtg
aacgcagccgacattgagagccgggtcttggagctgaacaagaagaaggagtcggaggac
tcggccaaagctggcttttgggaggagtttgagagcctgcagaagcaggaggtaaagaac
ttgcaccagcggctggaagggcagcggccagagaacaagagcaagaaccgctacaagaac
attctcccctttgaccacagccgagtgatcctacagggcagggacagtaacatccctggg
tccgactacatcaatgccaactatgtcaagaaccagctgctaggccccgatgagaacact
aagacctacatcgccagccagggctgtctggaggccacggtcaatgacttctggcagatg
gcctggcaggagaacacccgtgtcatcgtcatgaccacccgcgaggtggagaaaggccgg
aacaagtgtgtcccctactggcccgagttgggcacccagcgtgtctatggactctactcc
gtgagcaactgcagggagcacgacacggcagagtacaagctgcgcaccttacaggtctcc
ccactggacaacgggaacctagttcgggagatctggcactaccagtacttgagctggcct
gaccacggggtgcccagcgagcccgggggtgtcctcagcttcctggaccagatcaaccag
cgacaggaaagtctgcctcacgcaggccccatcatcgtgcactgcagcgcaggcatcggc
cgcacagggaccatcattgtcatcgacatgctcatggagagcatctccaccaaggggctg
gactgtgacattgacatccagaagaccatccagatggtgcgggcacagcgctcgggcatg
gtgcagacagaggcgcagtacaagttcatctatgtggccatcgcccagttcatcgaaacc
accaagaagaagctggaagtcatgcagtcccagaagggccaggagtcggagtatgggaac
atcacctacccccccgccatgaagaatgcccatgccaaggcctcccgcacatcctccaag
cacaaggagggatgtgtatga

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