Oryctolagus cuniculus (rabbit): 100351640 Help Entry 100351640         CDS       T03373                                  Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu04072   Phospholipase D signaling pathway ocu04115   p53 signaling pathway ocu04140   Autophagy - animal ocu04150   mTOR signaling pathway ocu04151   PI3K-Akt signaling pathway ocu04152   AMPK signaling pathway ocu04211   Longevity regulating pathway ocu04218   Cellular senescence ocu04714   Thermogenesis ocu04910   Insulin signaling pathway ocu04919   Thyroid hormone signaling pathway ocu05163   Human cytomegalovirus infection ocu05165   Human papillomavirus infection ocu05168   Herpes simplex virus 1 infection ocu05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ocu00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     100351640    04151 PI3K-Akt signaling pathway     100351640    04152 AMPK signaling pathway     100351640    04150 mTOR signaling pathway     100351640  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100351640  09150 Organismal Systems   09152 Endocrine system    04919 Thyroid hormone signaling pathway     100351640   09149 Aging    04211 Longevity regulating pathway     100351640   09159 Environmental adaptation    04714 Thermogenesis     100351640  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100351640   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     100351640    05165 Human papillomavirus infection     100351640  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:ocu01009]     100351640 Protein phosphatases and associated proteins [BR:ocu01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      100351640 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  100351640 NCBI-ProteinID:  XP_051695480 LinkDB All DBs Position Unknown AA seq 1809 aa AA seqDB search MAKPTSKDSGLKEKFKILLGLGTPRPSPRSAEGRQTEFVITAEILRELSVDCGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLRAIVQGQGEHLGALR ALFFRVIKDYPSNEDLHERLEVFKALTDNGRHIAYLEEELAEFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCIRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAVYNMCRLMEDRTYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEVVLSVSRLIKKYRKELQAVTWDL LLDIVERLLQQLQSLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLVSYRAQSIHPAKDGWIQNLQLLMERFFRNETRSAVRIKVLDVLSFVLLINRQFY EEELINTVVISQLSHIPEDNDHQVRKLATQLLVDLAEGCHTHHFNSLLDVIEKVTARSLS PPPELDERGAAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYETLVSHLQLHYKH NYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCLCDYIEPERSSEKKAS GPLSPPTGPPGPAHAGPAVRLGYLPYSLLFGLLLQCLKQETDWKVLKLVLSKLPESLRYK VLVFTSPCSLDQLSSALCSMLSGPKTLERLRGTPEGFCRTDLHLAVVPVLTALISYHNYL DKSKQREMVYCLEQGLIHRCAGQCVVALAVCSVEMPDIIIKALPVLVVKLTHISATASMA VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLMSFDDTPEKDSFRARSTSLNERPKSLRIARAPRPGLAHS PPVDECKGSPAAEAFRCRSVSVSEHGVRRIQTSLTSASLGSADENSMAQADDNLKNLHLE LTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLL GLDSGELQGGGPELSSDPGVHLRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG ALDPPTSHFPGSPSAPGTQAAPAAKPDRASAGTQGPAQERTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST ARPPPLPRSNTVASLSSLCPSSCQGKLHRSISWADSAVVLEEGGAGEASGLAEPPELEDQ GHCGRAGAYSRSSSASSQEEKLHAEDLAAGGVPIERAVSSAGGRPSVDLSFQPSQPLSKS SSSPELQTLQDILGDPGDKVDVGRLSPEAKARSQSGLLDGDGAAWAAADEEPQGLGPAQP EGALASGSPRSPGGLRPRGYTISDSAPSRRGRRADRVERDTFKSRAAATNAEKVAGINPS FVFLQLYHSPFFGDDSNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELA ILSNEHGSYRYAEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFH IATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIRGQFNFVHVIITPLDYEC NLVSLQCRKDMEGLVDTSMAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKW IARLRHIKRLRQRIREAAQYSNSSLPVLHTHTPAHAKAPAQAPAEPAPPYETGQRKRLLS SVDDFTEFV NT seq 5430 nt NT seq  +upstreamnt  +downstreamnt atggccaagccgacgagcaaggactccggcctcaaggagaagttcaagatactgctgggg ctggggaccccgaggccgagccccaggtccgcggagggcaggcagaccgagttcgtcatc accgccgagatcctgagggagctgagtgtcgactgtggcctcaacaatcgcatccgggtc atagggcagatctgcgaagtcgccaagacgaagaagttcgaagagcacgccgtggaagcc ctgtggaaggccgtggctgacctgctgcagccagagcggcctccggaagcccggcacgcg gtgctggccctgctgagagccatcgtgcaggggcagggggagcacttgggggccctcaga gccctgttcttcagggtcatcaaggattacccctccaacgaggacctgcacgagaggctg gaggtgttcaaggcactcacggacaacgggagacacatcgcctacctggaggaggagctg gccgagtttgtgctgcagtggatggacgtgggcttgtcctcggagttcctcctcgtgctg gtgaacttggtcaagttcaacagctgttacctggacgaatacatcgcctccatggttcac atgatctgcctgctctgcatccggacggcgtcctctgtcgacatagaggtctccctgcag gtgctggacgccgtggtctgctacaactgcctgccggccgagagcctcccactgttcatc gtcaccctgtgccgcactgtgaacgtcaaggagctctgtgagccctgctggaagctgatg cgcaacctcctgggcacccacctgggccacagcgccgtctacaacatgtgccgtctcatg gaggacagaacctacatggaggacgccccactgctgcgaggggctgtgttctttgtgggc atggccctctggggagcccaccgcctctactcgctcaagaactcgccgacgtctgtcctg ccgtccttttacgaggccatgacctgtcccaatgaggtggtgtcctatgaggtcgtcctg tccgtaagcaggctcatcaagaagtacaggaaggagctgcaggccgtgacgtgggacctt ctgctggacatcgttgagcgcctgctgcagcagctccagagcctggacagcccggagctc aggaccatcgtccacgaccttctgaccacggtggaggagctgtgtgaccagaatgagttc catggctcccaggagagatacttcgagctggtggagagatgtgcagaccagagacccgag tcctccctcttgaatttagtctcctacagagctcagtcaattcacccagcaaaggacggc tggattcagaacctgcagctgctgatggagcggttcttcaggaacgagacccgcagtgcc gtgcgcatcaaggtgctggacgtgctgtccttcgtgctgctcatcaacaggcagttctac gaggaggagctgatcaacacggtggtcatctcccagctctcccacatccccgaggataac gaccaccaggtccggaagctggccacccagctgctggtggacctggccgaaggctgccac actcaccacttcaacagcctgctggacgtcattgagaaagtgacggcccgctccctctct ccacctcctgagctggacgagaggggcgcggctgcctactcggcctccctggaggacgtg aagactgcggtcctggggctcctggtcatccttcagaccaagctgtacaccctgccggcc agccacgccactcgtgtgtacgagacgctcgtcagccacctgcagctgcactacaagcac aactacaccctgcccatcgccagcagcatccggctgcaggcattcgacttcctgctgctg ctgcgcgccgactccctgcaccgcctgggcctgcccaacaaggatggggtggtgcggttc agcccgtactgcctctgcgactacatcgagccggagcggagctctgagaagaaggccagc ggccccctttcccctcccaccgggccgcctggccctgcacacgcaggccccgctgtgcgg cttggctacctgccctactccctgctcttcggcctcctcctgcagtgcctgaagcaggag acggactggaaggtgctgaagctggtgctcagcaagctgcccgagtctctgcgctataag gtgctcgtcttcacctccccctgcagcctcgaccagctgtcttccgcgctctgctccatg ctttcaggcccaaagaccctggagcggctccggggcactccagaaggcttctgcaggacc gacctgcacctggctgtggtcccagtgctcacggcgttgatctcctaccataactacctg gacaagagcaagcagcgggagatggtgtactgcctggagcaagggctgatccaccgctgt gccggccagtgcgtggtggccctggccgtgtgcagcgtggagatgcccgacatcatcatc aaggccctgcccgtcctggtggtgaagctcacgcacatctccgccacagccagcatggcc gtcccactgctggagttcctgtccactctggcccggctgccgcacctctacaggaacttc gccgcagagcagtacgccagcgtgttcgccatctcgctgccctacaccaacccctccaag ttcaaccagtacatcgtgtgcctggcccaccacgtgatcgccatgtggttcatcaggtgt cgcctgcccttccgcaaggacttcgtcccctacatcaccaagggcctgcgctccaatgtg ctgatgtcttttgatgacacccctgagaaggacagcttcagagcgcggagcaccagcctc aacgagcggcccaaaagtctgaggatagcccgagcccccagaccaggcttggcccactct ccacccgtggacgagtgcaaggggagccccgccgccgaggccttccggtgccgcagcgtc agtgtgtctgaacatggggtccgcaggatccagacgtcgctcaccagcgccagcctgggg tccgcagatgagaactccatggcccaggctgacgacaacttgaaaaacctccacctggag ctcacagaaacctgcctggacatgatggcccgatacgtgttctccaacttcacggccgtg cccaagaggtcccccgtcggagagttcctcctggccggcggcaggaccaaaacctggctg gtggggaacaagctcgtcacggtgacgacaagcgtggggactgggacccggtccctgctg ggcctggattccggggagctgcagggcggcggcccagagttgagctctgaccctggcgtg cacttgagacagacaaaggaggcaccggccaagctggagtcccaggccgggcagcaggtg tcccgtggggcccgggaccgcgtccgttccatgtcgggaggccacggccttcgggtcggt gccctggacccaccgacctcccacttccccggcagcccgtctgctccgggaacacaggct gcgccagctgcgaagcctgacagggcctcagcaggcacccagggcccagcacaggagagg acgaacctggccgcctacgtgcctctgctgacccagggctgggctgagatcttggtccgc aggcccacagggaacacaagctggctgatgagcctggagaacccgctgagccccttctcg tccgacatcaacaacatgcccctgcaggagctgtccaacgccctcatggcggccgagcgc ttcaaggagcatcgcgacaccgccctgtacaagtcgctgtccgtgccggccgccagcaca gccaggccccctcctctccctcgctctaacacagtggcctctctgtcctccctgtgcccg tccagctgccaggggaagctgcacaggagcatttcctgggcagactcggcagtggtgctg gaggagggcggtgcaggagaggcctccgggctggcggagcccccagagctggaggaccag gggcactgcgggcgtgccggtgcctacagcaggtcgtcttcagcatctagccaggaggag aagctgcacgcggaggatctggctgctgggggcgtccccatcgagcgggccgtgtcctct gcgggcggccggccctcggtggacctgtccttccagccctcgcagcccctgagcaagtcc agttcctcccctgagctgcagaccctgcaggacatcctgggggaccctggggacaaggtg gacgtgggccggctcagtcctgaggccaaggcccggtcacagtcggggcttctggatgga gacggtgctgcctgggcagctgctgacgaggagccccagggcctgggcccagcgcagcct gagggtgccctggcctccggctcaccccgctcgcccggcggcctccggccccgaggatac accatctccgattccgccccgtcgcgcaggggccggcgggcagacagggtggagagggac accttcaagagcagagccgcggccaccaacgccgagaaagtagccggcatcaaccccagc ttcgtgttcctgcagctctaccactcgcccttctttggcgacgactccaacaagcccatc ctgctgcccaacgagtccttcgagcgctcggtgcagctcctggaccagattccgtcctac gacacgcacaagatcgccgtgctgtatgtgggagagggccagagcaacagcgagctggcc atcctgtccaacgagcacggctcctaccggtacgcggagttcctgacggggctcggcaag ctcatcgaactcaaggactgccagcccgacaaggtgtacctgggcggcctggacgtgtgc ggcgaggacggccagttcacctactgctggcacgacgacatcatgcaagccgtcttccac atcgccaccctgatgcccaccaaggacgtggacaagcaccgctgtgacaagaagcgccac ctgggcaacgacttcgtctccatcgtctacaacgactctggcgaggacttcaagctgggc accatcagaggccagttcaactttgtgcacgtgatcatcacgccactggactacgagtgc aaccttgtgtccctgcagtgcaggaaggacatggaaggcctggtggacaccagcatggcc aagatcgtgtctgaccgcaacctcccgttcgtggcccgccagatggccctgcatgcgaac atggcctcgcaggtgcaccacagccgctccaaccccaccgacatctacccctccaagtgg atcgcccggctgcggcacatcaagcggcttcgccagcggatccgcgaggcggcccagtac tccaactccagcctgccggtgctgcacacgcacacgcccgcccacgccaaggccccagcc caggccccggccgagccggcgcccccctacgagacgggccagcgcaagcgcctcctctcc tccgtggatgacttcacggagttcgtgtga

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