Oryctolagus cuniculus (rabbit): 100357346
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Entry
100357346 CDS
T03373
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu04140
Autophagy - animal
ocu04141
Protein processing in endoplasmic reticulum
ocu04210
Apoptosis
ocu04932
Non-alcoholic fatty liver disease
ocu05010
Alzheimer disease
ocu05012
Parkinson disease
ocu05014
Amyotrophic lateral sclerosis
ocu05016
Huntington disease
ocu05017
Spinocerebellar ataxia
ocu05022
Pathways of neurodegeneration - multiple diseases
ocu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100357346
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100357346
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100357346
05012 Parkinson disease
100357346
05014 Amyotrophic lateral sclerosis
100357346
05016 Huntington disease
100357346
05017 Spinocerebellar ataxia
100357346
05022 Pathways of neurodegeneration - multiple diseases
100357346
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100357346
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100357346
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocu01001
]
100357346
Enzymes [BR:
ocu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100357346
Protein kinases [BR:
ocu01001
]
Serine/threonine kinases: Other
IRE family
100357346
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
100357346
NCBI-ProteinID:
XP_008269931
Ensembl:
ENSOCUG00000012090
UniProt:
G1T2L4
LinkDB
All DBs
Position
19:complement(46427568..46522337)
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AA seq
975 aa
AA seq
DB search
MPARRLLLFLALLLPSSGIFGSSSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYGSPVVAFYVWQREGLRKV
MHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINMVDQTSENTPTTVSP
DVEEKLARAPAKAEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLNMHQQQQLQHQQFQ
KELEKIQLLQQQQLPFPPPGDVTQDADLLDACSPYSESSGTSSPSTSPRASNHSLHSSGS
ASRAGASLSLEPDDEDEEASMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRNVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFFHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGKIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCFHPEKHEDVVARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSIRDLLR
AMRNKKHHYRELPPEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMELCSQERLFQPYYS
HEPPELRPPVTPDAL
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggttgctgctgttcctggcgctgctgctgcccagctctgggatattt
ggaagttccagcacagtgacacttcctgaaaccttgttgtttgtatcgaccctggatgga
agtttgcatgctgtcagcaagaggacaggctcaatcaagtggactttaaaggaagatcca
gtcctgcaggtcccaacacatgtggaagagcctgcattcctcccagatcctaatgatggc
agcctgtatacacttggaggcaagaataatgaaggcctgacaaaacttccctttacaatc
ccggagttggtacaggcatccccgtgccgaagttccgacggcatcctttacatgggtaaa
aagcaggacatctggtacgtcatcgatctcctgaccggggaaaagcagcagactttgtca
tcggcctttgcagacagtctctgtccatcaacttcacttctgtatcttgggcgaacagaa
tataccatcaccatgtatgacaccaaaaccagagagctccggtggaacgccacctacttt
gactacgcagcctcacttcctgaagatgacatggactacaagatgtcccactttgtgtcc
aatggcgatgggctcgtggtgaccgtcgacagtgaatctggagacgtcctgtggatccaa
aactatggctcccctgtggtggccttctatgtgtggcagcgggagggtctgcggaaggtg
atgcacatcaacgtggccgtggagaccctgcgctacctgaccttcatgtctggggaggtg
gggcgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctg
acgcccactctgtatgttgggaaatactcaaccagcctctacgcctccccgtcaatggta
catgaaggggttgctgtcgtgccccgaggcagcactcttcctttgctggaaggcccccag
accgatggtgtcaccataggggacaaaggggagtgtgtgatcacgcccagcacggacctc
aagtttgaccccggactcaaagggaaaaacaaacttaactacttgaggaattactggctt
ctgataggacaccatgaaaccccactgtctgcctctaccaagatgctggagagattcccc
aacaatctgcccaaacatcgggaaaatgtgattcctgctgattctgagaaaaagagcttt
gaggaagttatcaacatggttgaccagacttcagagaacacaccgaccaccgtgtctcca
gacgtggaagagaaactggctcgtgcccctgccaaggccgaggcccctgtggactccatg
ctcaaggacatggccaccatcatcctgagcacctttctactgatcggctgggtggccttc
atcatcacataccccctgaacatgcatcagcagcagcagctccagcaccagcagttccag
aaggagctggagaagatccagctcctgcagcagcagcagctgcccttccccccacccgga
gacgtgacgcaggacgctgacctcctggacgcctgcagcccatactcggagagctcgggc
accagcagccccagcacgtcccccagggcctccaaccactcactgcactccagcggctct
gcctccagggctggggccagcctctccctggagccggatgatgaggatgaggaagccagc
atggtgatggttgggaagatttcattctgtcctaaagacgtcctgggccacggagctgag
ggcacaattgtgtaccggggcatgtttgacaaccgcaacgtggccgtgaagaggatcctc
cctgagtgtttcagcttcgccgaccgtgaggtgcagctgctgcgagaatcagacgagcat
ccgaacgtgatccgctacttctgcacggagagggaccggcagttccagtacatcgccatc
gagctgtgcgcggccaccctgcaggagtatgtggagcagaaggacttcttccaccttggc
ctggagcccatcaccttgctgcagcagaccacctcgggcctggcgcacctccactcgctc
aacattgttcacagagacctgaaaccccacaacattctcctctccatgcccaatgcacat
ggcaagattaaggctatgatctctgacttcggcctctgtaagaagctggcagtgggcagg
cacagcttcagccgccgttctggggtgcccggcacagagggctggatcgccccggagatg
ctgagtgaagactgcaaggagaaccctacctacacagtggacatcttctctgcgggctgc
gtcttttactacgtcatctctgagggcagtcacccgtttggcaagtccctgcagcggcag
gccaacatcctcctgggtgcctacagccttgactgcttccacccagagaagcacgaggat
gtcgttgcccgggagctgatagagaagatgatcgccatggaccctcagaagcgcccctcg
gcgaagcacgtgctcaaacacccgttcttctggagcctggagaagcagctccagttcttt
caggatgtgagtgaccggatagaaaaggagtccctggacggcccgatagtgaggcagctg
gagcgaggcgggagagctgtggtgaagatggactggcgggagaacatcaccgtcccgctg
cagacagatctgcgtaaattcagaacctataaaggtggctccatcagagacctcctccga
gccatgagaaacaagaagcaccactaccgggagctcccgccggaggtgcgcgagacgctg
ggctccctccccgacgacttcgtgcgctacttcacgtcccgcttcccccacctcctctca
cacacttaccgggccatggagctctgcagccaggagagactcttccagccctactactcc
catgagcccccggagctccggcccccagtgactccggacgccctctga
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