Otolemur garnettii (small-eared galago): 100959432
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Entry
100959432 CDS
T07855
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00061
Fatty acid biosynthesis
oga00620
Pyruvate metabolism
oga00640
Propanoate metabolism
oga01100
Metabolic pathways
oga04152
AMPK signaling pathway
oga04910
Insulin signaling pathway
oga04920
Adipocytokine signaling pathway
oga04922
Glucagon signaling pathway
oga04931
Insulin resistance
oga04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100959432 (ACACB)
00640 Propanoate metabolism
100959432 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100959432 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100959432 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100959432 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100959432 (ACACB)
04922 Glucagon signaling pathway
100959432 (ACACB)
04920 Adipocytokine signaling pathway
100959432 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100959432 (ACACB)
04931 Insulin resistance
100959432 (ACACB)
Enzymes [BR:
oga01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100959432 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100959432 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100959432 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100959432
NCBI-ProteinID:
XP_012660700
Ensembl:
ENSOGAG00000007444
LinkDB
All DBs
Position
Unknown
AA seq
2458 aa
AA seq
DB search
MVLLLFVSCLIFSCLTFSWLRIWRKMTDSQPVTKSKSEVSSTQSQEPFPASDSFGEPPQK
NGDGSSLPKTPQQAEPVSRRGPKDACQRRNSLPPSHQKPPRNPLSSTDASPSPGLQSNGA
ESEGPEAPDTNGLSSLPQPQGQRARSPSKEDKKQANIKKQLMTNFILGSFDDYSSDEDPG
TGSFRESSRKGSRASLGTVTLEVPLTTGEPDTRIPTMRPSMSGLHLVKRGREHKKLDLHR
DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT
PEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL
PELLCKDGIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTDDDLQQGK
RISVPEDVYEKGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV
QSEIPGSPVFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAP
LAVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL
PAAQLQIAMGVPLHRLKDIRLLYGESPWGVMPISFETPANPPLARGHVIAARITSENPDE
GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA
LKELSIRGDFRTTVEYLINLLETDSFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGAL
NVADAMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGIKYILKVARQSLTMFVLIM
NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP
SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCMVAR
LELDDPSKVHPAEPFMGELPSQQTLPILGEKLHQVFHNVLENLTNVMSGYCLPEPIFSIK
LKEWVQKLMVTLRHPSLPLLELQEIMTSVSGRIPTPVEKAVQRVMAQYASNITSVLCQFP
SQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYLHV
EHHFQQAHYDKCVINLREKFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD
ELTSILNELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCP
ENLKKLILSETTIFDVLPSFFYHTNKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV
VEFQFMLPSSHPNRMAMPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFERFEDFTR
NFDEVISCFANVPKDTPLFSKARTSLYSDDDCKSLREEPIHILNVAIQCADRLEDEALVQ
TLRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL
ELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRAIIRHSDLITKEASFEY
LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGS
RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKELTDPRSGNIMFHSF
GNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYIYDFPEMFRQALFKLWGSPDKYPK
DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG
SFGPREDLLYLRASEMARAEGIPKIYLAANSGARIGMAEEIKHMFQVAWVDPEDPQKGFK
YLYLTPQDFTKISSLNSVHCKHIEEGGESRYVITDIIGKDDGLGVENLKGSGTIAGESSL
AYEEIVTISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL
GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNLSPVPIITPTDPIDREIEFLPSR
APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPIGVIAVE
TRTVELVVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIEDFRREKLPLLIFANWRGF
SGGMKDMYDQVLKFGAYIVDGLRKYTQPILIYIPPYAELRGGSWVVVDATINPLCIEMYA
DKESRGGVLEPEGTVEIKFRKKDLIKSMRRLDPVYKKLVEQLGAPELSEKERKDLDSRLK
AREDMLFPIYHQVAVQFADLHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVR
QEILRASGQLSHVHIQSMLRRWFVESEGAVKAYLWDNNQVVVQWLEQHWQAEDGPHSTIS
ENIRCLKHDSVLKTIRGLVQENPEVAMDCVMYLSQHISPAERAQVAHLLSTLESPAST
NT seq
7377 nt
NT seq
+upstream
nt +downstream
nt
atggtattacttctttttgtatcttgtctgattttctcctgcctgaccttttcctggtta
agaatctggcgcaaaatgacagactcacagccagtcactaagagtaaatcagaagtgagc
tccacccagagccaggagcccttcccagcctcagacagctttggggagccaccgcagaag
aatggcgatggcagctctctgccgaagactccccagcaggcagagccagtctcccgcaga
ggccccaaagatgcctgtcagcggagaaactccttgccaccctcacaccagaagcctcca
agaaaccccctttcttccactgatgcatcaccttccccaggactccaatccaatggcgca
gagagtgaaggcccggaagccccggataccaatggtctgtcctccctaccccagccccag
ggccagcgagctcgatccccctccaaagaagacaagaagcaggcgaacatcaagaagcag
ctgatgaccaacttcatcctgggctcgtttgatgactactcctccgatgaggaccctggt
actggctcatttcgtgagtcttcccggaagggcagccgggccagcctagggacagtgacc
ctggaggtgcctctgaccacgggtgaacctgacacccgcatccctacaatgaggccaagc
atgtctggactccacctagtgaagaggggacgggaacacaagaagctggatctacacaga
gacttcactgtggcttccccagctgagtttgtcacacgctttggaggggatcgggtcatc
gagaaggtgcttattgccaacaatggtattgctgccgtgaagtgcatgcgttccatccgc
aggtgggcctatgagatgttccgcaatgagcgggccatccggtttgtggtcatggtgacc
cctgaggacctcaaggccaatgcagagtacatcaagatggcggatcagtacgtccctgtc
ccaggagggcccaacaacaacaactacgccaatgtagagctgatcgtggacattgccaag
agaatccctgtgcaggcggtgtgggctggctggggccatgcttctgaaaaccccaaactt
ccggagctgctgtgcaaagatggaattgctttcttaggccctcccagtgaggccatgtgg
gccttgggagacaagattgcctccaccatcgtggcccagacgctgcagataccaactctg
ccttggagtggtagtggtctgacagtggagtggacagacgatgatctgcagcaagggaaa
agaatcagtgtcccggaagacgtgtatgaaaagggttgtgtgaaagatgtagacgagggc
ttggaggcagcagaaaaaattggttttccattgatgatcaaagcgtctgaaggtggtgga
gggaaaggaatccggaaggctgagagtgcagaggacttcccgatccttttcagacaggtg
cagagtgagatcccgggctcaccggtctttctcatgaagctggcccagcacgcccgtcac
ctggaggtgcagatcctcgctgaccagtacgggaacgcggtgtctctgtttggccgagac
tgctctatccagcggcggcatcagaagatcattgaggaggcgccggccaccatcgccccg
ctggctgtgttcgagttcatggagcagtgtgctgtccgcctagccaagacggtgggctat
gtgagcgcggggacggttgaatacctctatagccaggacggcagcttccacttcttggag
ctgaatcctcgcctgcaggtggaacatccctgcacagaaatgatcgcggacgtcaacctg
ccggctgcccagctacagatcgccatgggagtcccattgcaccggctgaaggatatccgg
cttctctatggagagtcgccatggggagtgatgcccatttcttttgaaacccctgcaaat
ccccccctcgctcgaggccacgtcattgcagccagaatcaccagcgaaaacccagacgag
gggtttaagccaagttctggcacagtccaagaactgaatttccgcagcagcaagaacgtg
tggggttacttcagcgtggctgctactggaggcttacatgagtttgctgattcccagttt
gggcactgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggct
ctgaaggaactgtccatccgaggtgactttaggaccaccgtggagtatctcattaacctc
ctagagactgacagcttccagaacaacgacattgacaccgggtggttggaccacctcatc
gctgaaaaagtgcaggccgagaagccggatatcatgctcggggtggtgtgtggggccttg
aacgtggccgacgcgatgttcagaacctgcatgacggatttcttacactccctggagagg
ggccaggttcttccggcagattcactgctgaacattgtggatgtggagttaatttatgga
ggcattaagtacattctcaaggtggcccggcaatctctgaccatgtttgtactcatcatg
aacggctgccacatcgagattgatgcccaccggctcaatgacggtgggctgctgctgtcc
tacaacgggaacagctacactacctacatgaaagaagaggtggacagttaccgaattacc
atcggcaacaagacgtgtgtatttgagaaggagaacgatcccacagtcctgagatctccc
tcagctgggaagctgacacagtacacagtggaggatgggggccacgtcgaggctgggagc
agctacgcagagatggaggtgatgaagatgatcatgaccctgaacgtgcaggaaagtggc
cgggtgaagtacattaagcgtcctggggccgtgctggaggcaggctgcatggtggccagg
ctggagcttgacgatccttctaaagtgcacccagctgagccattcatgggagagctgccg
tcccagcagacactgcccatcctcggagagaaactgcaccaggttttccacaatgtccta
gaaaacctgaccaatgtcatgagtggctactgtctgccagagcctatttttagcataaag
ctgaaggagtgggtgcagaagctcatggtgactctgcggcacccctcactgccgctgctg
gagctgcaggagatcatgaccagcgtgtcgggccgtatccctacccccgtggagaaggca
gtccagcgggtgatggcccagtacgccagcaatatcacctcggtgctgtgccagttcccc
agccagcagatagccaccatcctggactgtcacgcggccaccctgcagcggaaggctgac
cgagaggtcttcttcatgaacacgcagagcatcgtacagttggtgcagagataccgcagt
gggacccgcggctacatgaaaacggtggtgttggatctccttagaagatacttgcatgtc
gagcaccatttccaacaagcccactacgacaagtgtgtgatcaacctcagggagaagttc
aagccagacatgtcccaggtgctggactgcatcttctcccacgcacaggtggccaagaag
aaccagctggtgatcatgttgatcgatgagctctgtggcccagacccttccctgtcggat
gagctgacctccatcctcaatgagctcactcagctgagcaaaagcgagcattgcaaggtg
gccctccgagccagacaggtcctgatcgcctcccatctcccctcctatgagctgcgtcac
aaccaggtggagtccatcttcctgtctgccattgacatgtacggccaccagttctgccca
gagaacctcaagaaattaatactttcggaaacgaccatctttgatgtcctgccttcattc
ttctatcacactaacaaagtcgtgtgcatggcgtccttggaggtttatgtgcggaggggc
tacatcgcctatgagttaaacagcctgcagcaccggcagctcccggacggcacgtgcgtg
gtagaattccagttcatgctgccctcttcccacccaaaccggatggccatgcccatcagc
atcaccaaccctgacctgctgaggcacagcacggagctcttcatggacagcggtttctcc
ccactctgccagcgcatgggggccatggtggccttcgagagattcgaggacttcaccagg
aactttgatgaggtcatctcctgctttgccaatgtgcccaaagatacccccctcttcagt
aaggcccgaacctccctgtactccgacgatgactgcaagagcctcagggaagagcccatc
cacattctgaatgtggccatccagtgtgcagaccgcctggaggacgaggcgctggtgcag
accttacggactttcgtgcagtccaagaaaaatattcttgtggattatggactccgaagg
atcacattcctgattgcccaggagaaagaatttcccaagtttttcacattcagagcaaga
gatgagtttgcagaagatcgcatttaccgtcacttggagccggccctggccttccagctg
gagctcagccggatgcgcaacttcgacctgaccgccgtaccctgcgccaaccacaagatg
cacctttacctgggtgcggccaaggtgaaggaaggggcagaagtgacggaccaccggttc
ttcatccgggccatcatcaggcattccgacctgatcacgaaggaggcctccttcgagtac
ctgcagaacgagggagagcggctgctcctggaggccatggacgagctggaggtggccttc
aacaacaccagtgtgcgcaccgactgcaaccacatcttcctcaacttcgtgcccaccgtc
atcatggacccctccaagattgaggagtctgtacgctccatggttatgcgatatggcagc
cgcttgtggaaactccgagtgctacaggctgaggtcaagatcaacatccgccagaccacc
acgggcagtgccgtccccatccgcctgttcatcaccaacgaatcgggctactacctggac
atcagcctgtacaaagagctgaccgacccgagatctggaaacatcatgtttcattccttt
ggcaacaaacaagggccccagcacgggatgctgatcaatactccctatgtcaccaaggat
ctgcttcaggccaagcgattccaggcccagtccttggggaccacctacatctatgacttc
ccagagatgttccggcaggccctctttaaactgtggggctccccagacaagtacccgaaa
gacatcctgacgtacacggaattagtactggactctcagggccagctggtggagatgaac
cgacttcctggtggaaacgaggtgggcatggtggccttcaaaatgcggttcaagacccag
gagtatccggaagggcgggatgtgattgtcatcggcaatgacatcaccttccgcattggc
tcctttggcccacgggaggaccttctgtacctgagggcatctgagatggcccgggcagag
ggcatccctaaaatctacctggcagccaacagtggggcccgcatcggcatggcagaggag
atcaaacacatgttccaggtggcttgggtggacccagaagacccccaaaaaggatttaag
tacctgtacctgactccccaagacttcaccaaaatcagctccctgaactccgtccactgt
aaacacatcgaggaaggaggagaatccaggtacgtcatcacggatatcattgggaaggac
gatggcctgggcgtggagaatctgaagggctcgggcaccattgctggggagtcctccttg
gcttatgaagagattgtcaccattagcttggtgacttgccgagcccttgggatcggagcc
tacttggtgaggctgggccagcgagtgatccaggtggaaaactcccacatcatcctcaca
ggagcaagtgctctcaacaaggtcctgggaagagaggtctacacgtccaacaaccagctg
gggggcgtgcagatcatgcattacaatggtgtctcccacatcaccgtgccagatgacttc
gagggcgtctataccatcctagagtggctgtcctatatgccaaaggataatctcagccca
gtccctatcatcacacccactgaccccattgacagagaaattgaattcctcccatccaga
gctccctacgatccccggtggatgcttgcaggaaggcctcacccaactttgaagggaacc
tggcagagtggattcttcgaccatggcagcttcaaggaaatcatggcaccctgggcccag
accgtggtgacaggacgagcaaggctgggcgggatccccattggagtgatcgctgtagag
acccggacagtggaattggtggtccctgcagaccctgccaacctggattctgaagccaag
ataatccagcaggcgggccaggtgtggttcccagactccgcctacaaaaccgcccaggcc
atagaggacttcaggagggaaaagctgccccttctgatctttgccaactggaggggcttc
tctgggggtatgaaagacatgtatgaccaggtgctgaagtttggcgcctacatagtggat
ggcctcaggaagtacacacagcctatcctgatctacatcccaccctacgcagagctccgg
ggaggctcctgggtggtcgtcgatgccaccatcaaccccctatgcatagaaatgtacgcc
gacaaagagagcaggggaggtgttttggagccagagggaacagtggagattaagttccga
aagaaagacctgatcaagtccatgagaaggctcgacccagtttacaagaagctcgtggaa
cagctgggggcgccggagctctcagagaaggagcgcaaggacctggacagccggctgaag
gctcgcgaggacatgctgttccccatctaccaccaggtggcggtgcagttcgccgacctc
cacgacacacccggccggatgctggagaagggtgtcatctctgacatcctggagtggaag
acggcacgcaccttcctgtactggcgtctgcgccggctcctcctggaggaccaggtccgg
caggagatcctgcgggccagcggccagctgagccatgtgcacatccagtccatgctgcgc
cgctggtttgtggagtcggagggtgccgtcaaggcctacctgtgggacaacaaccaggtg
gtggtgcagtggctggagcagcactggcaggcggaggatggcccgcactccaccatcagt
gagaacatcaggtgcctgaagcacgactccgtcctcaagaccatccgaggcctagtccaa
gaaaaccctgaggtggccatggactgcgtgatgtatctgagccagcacatcagcccagcc
gagcgggcccaggttgctcacctgctgtctaccctggagagcccagcctccacctga
DBGET
integrated database retrieval system
