Oncorhynchus mykiss (rainbow trout): 110522969 Help Entry 110522969         CDS       T07259                                  Symbol obscna Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism omy  Oncorhynchus mykiss (rainbow trout) Pathway omy04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:omy00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     110522969 (obscna)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:omy01001]     110522969 (obscna)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:omy04131]     110522969 (obscna) Enzymes [BR:omy01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      110522969 (obscna) Protein kinases [BR:omy01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    110522969 (obscna) Membrane trafficking [BR:omy04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     110522969 (obscna) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Ig_4 Izumo-Ig SOS1_NGEF_PH V-set_CD47 RhoGEF C2-set_2 Kdo PH ABC1 fn3 Kinase-like IQ_SEC7_PH IQ RIO1 PH_19 RHG20_PH DUF919 APH Motif Other DBs NCBI-GeneID:  110522969 NCBI-ProteinID:  XP_036834945 LinkDB All DBs Position 5:54083355..54168958 Genome browser AA seq 6640 aa AA seqDB search MGDKSGSKVAAAKNQIHLRVVKGLEDVDVREREGCTFEVTLNLSYIAGTWTKDGVRLQAK PTCRIAAHKNKHTLTFTRVTVGDTGLFSFQTDGTQNWIQTSGQLTVIARDIQIVKELEDE EVTERQSVTFLCEVNCEDVDGRWYSDNTRIKHGDNVKIRHEGKTHTMCFKSVRPANAGEI KFTADRVSCYATLTVKELPVQIVKPLRVKIAMYKHKGLLECQVSRANALVRWFKNRSEIQ PSKKHQIVSDDVYRQLHIDDVASSDEDTYTCDAGDDKTSCQLLVEEQAISIVQGLRSVEV TEPREALFQVETSLRAGRPPKWTLDGEVLMDGPELSIDRQGTLHTLCFISTDSSMTGPVQ FNAGKSRSTAQLTVKERPLKVVQPMPDVEAKENSSVTLRCQFAPSPRVVRWYRGRTALQT SSKYSMRTEKNQAELTIQGLKETDTGQYSCMAGGSKSTAKVDVQRLKIVRHLEHVKVEED SNATFTCELNYVVANVQWLLNDNHLNANTVTRIQNMGTIHSLTIKNLRPQESRVTFKAGL LTESTSLKVKEKPAVFLRSLEDMSGEEEGKVCLQCETSKEMATPVWRKDGTVLDSSDKYE LLMFGKSLTLIIHSLSKDDAGHYSCDLGTSQTKAKVTVHDIHITIAQRMKTVSVLEGESC SFECILSHDVIDEPSWTLNGRLVISNSRIQIVNKGRKYKMTIRDATVTEAGDVIFFIKDL SCRTMLFVKEKPVHVFRDMMSIKATPGENAELSCEITKPEAFIRWLKNGHQIRHSPPKYE ISVEDHLVRLVITNTCIRDSGEYCCEADGIATRAKLEVRELQHTFARELRDTRAEEKSKV MLECETRLPAKRVTWLKGMAELRAGRKYVMKQKGVVLYLTISCLEKVDTDVYTCDVGTMQ SRALLTVHGQKVLILDELEDVECLENDTVMFRCRICPSDYVGVKWYLDETLLYTNELNEI QVIPGGYHSLTFKQLARKDSGTISFEAGDKRSYASLLVRERRPTITKALEDCEAIEGGGL VLVCITSKPCHILWYKDGCLMWISSRYHVSRSGNEARLTIREVSNSDAGVYECSAGSVST KAVVTVKAIPAEFTQPLQSMEVKEGEDVTLSCEFSLPGVAFHWKRGLETLRAGERYLMKQ KRSFISLTITGPKPQDSGDYTCQCRDHRTTASLTVHAIPISFTQQLKNVQAEEGNSLTLR CELSKPGVPVEWRKGEELLKNGVKFQIRKRETILEVQIWKTVPEDSGVYSCECADQKTTA TVKISALPVTFKQKLRNVHVEEGNNLVLHCELSKPGVPVEWMRGGEELLNNGERFQIRQR ELVNELKIIDAKPEDSNIYTCVCGNVETTAGVTVTAIPITFKQKLRNLQTEEGNTISLHC ELSKAGVPVEWRLGGERILQNGDKYQIKQTDSALELLIREALPEDSGVYSCVCRDKKTKA TVKVIAVPATFKVGLKNQEAPEEGSITLHCELSKAGVSVEWRRGETELSQDLSGGKYQMK LEGKIAEMTITNVKPEDIGKYSCVTGDQKTTAEVKVQALPVMFTQEVQNVVIKEGDSGEF WCELSKPGDPVDWRRGRVLLKSGDKYEMRQEGRITKLLIHNVEERDAGKYTCKSRDAKST AELTVTGPPPTFKEQLRNVEVEEGKTVTLHCELSKAAASVEWKRGAKLLTNVAKYQMRKK DLLVELKIIDANLEDSGVYACVCGEQKTTATVTIKARPVTFIEELRNVQVEEGNTVTLRC ELSKPGMSVEWRRGTALLQNGEKYQMKQKDATLELVIRKTLAEDSGVYSCVLEDQQTFAT IIITAIPATFKQTLKNQEALEEGSVTLRCELSKSGVSVVWLKGEELLREGERHQMKQEGR TVEMVIRNAVLQDAGEYSCVTACNVKTTADIKVRALPVMFTQEVQDMVIKEGDSGEFWCE LSKPGDPVDWRRGRVILKSGDKYEMRQEGRITKLLIHNVEERDAGKYTCKSRDAQSTAEL TVTAPPVTFKVKLKNQEVEEENSVTLFCELSKPGLTAEWRKGEELLKNGVKYQIKKREAT MELTIRNAVLEDTGFYSCVYAEAKTTATVNITPIPVTFKMGLKNQEASEGGIVTLRCELS KAGVPVEWWKGEEEVSPGGRYQMKLEGKIAELHIKNIQPEDVGEYSCIFEDQKTTAEVNV RGTVCYCCLAVILCLLDMKCSFTKKQRVDVWTSPATAPKCYRIRNKQEVNAIALSRNKTI PAASVFFEKELESNVVMEGKSMVLSCEVSSATVPVTWKKDACLVTDGERFIVKKKGPVHT LEIEKLSLEDAGEYSCITRGKKTTAMLVVKERVKILSGLKDMKVTAGQDAVFVCELSHAE VSEGEWWLGSSPLQKNEMNQMSFEGHQHCLVLTMTTPEETGTVAFVVGEERTSAQLLVVP KPKVHIEKKPQDIDIMEGETATLSCTTSDLITPVTWRRNSMPLLNGDKYETRKKGKLNLL LIHETEPEDSGIYSCDTGDMQSGANLTVNELPPYFEEELQCVEAEEGGTAFLFCELSKPG VPIQWRKGRLPLRPNRKYQMKQDGCVFQLHILELKSEDSGSYSCQAGCVETTASVSVKVK VLIEKKPQDTVIMEGETATLSCTTSDLTTPVTWRRNNITILNGDKYENRKEGKLNLLLIH NVDPDDSGLYSCDTGDMQSSAKLTVTELAPCFEEELQAVEAEEGGTAFLSCELSKPGVPV QWSKGRLPLRPNRKYQMKQDGCVFQLHILELKSEDSGSYSCQAGCVETTASVSVKVKVLI EKKPQDTVIMEGETATLSCTTSDLTTPVTWRRNNITILNGDKYENRKEGKLNLLLIHNVD PDDSGLYSCDTGDMQSSAKLTVTELAPCFEEELQAVEAEEGGTAFLSCELSKPGVPVQWS KGRLPLRPNRKYQMKQDGCVFQLHILELKSEDSGSYSCQAGCVETTASVSVKVKVLIEKK PQDTVIMEGETATLSCTTSDLTTPVTWRRNNITILNGDKYENRKEGKLNLLLIHNVDPDD SGLYSCDTGDMQSSAKLTVTELAPCFEEELQAVEAEEGGTAFLSCELSKPGVPVQWSKGR LPLRPNRKYQMKQDGCVFQLHILELKSEDSGSYSCQAGCVETTASVSVKVKVLIEKKPQD TVIMEGETATLSCTTSDLTTPVTWRRNNITILNGDKYENRKEGKLNLLLIHNVDPDDSGL YSCDTGDMQSSANLTVTELPPYFEEELQAVEAEEGETAFLSCELSKPGVPVQWRKGRLPL RPNRKYQMKQDGCVFQLHILELKSEDSGSYSCQADGVETTTSVSVKVKVLIEKKPRDTVI MEGETATLSCTTSDLTTPVTWRRNNMPLLNGDKYENRKEGKLNLLLIHNVDPDDSGIYSC DTGDMQSSVNLTVTELPPYFEEELQAVEVEEGGTACLSCELSKPGVPVQWKKGRLPLRPN RKYQLKQDDCVFQLHILELKPEDSGSYTCQAGGVKTTASVAVKPLPAKTEPPKTMPPTKA PTKAASPTPPPGPKKQGMIWASIVGSEKDLEPEAGTVVDLHEKQSVRSIGKETKVDQQEK QQVKQTVRAMVRDTEEKKPLKSMVKEIEVDHMVKQPVPPARRASIMSDTGIDQVVKQPVP LVRQESIMSDTGIDQVVKQPVPLVRQASIMSDTGIDQVVKQPVPPVRRPSIMSYTGVDEV RKQPVPPVRQASVVSDAGIDQVVKQPVPPVRRASIVSDVGVDEVRKQPVPPVRQASVVSD AGIEQVVKQPVPPARRASVVSVSDTGVDEVRKQPVPPVRRASVVSDAGIEQVVRKQPVPP ARRASVVSVSDTGVDEVRKQPVPPVRRASVVSDAGLDEVRKQPVPPVRRASVVSDAGIEQ VVRKQPVPPVRRASIVSDAGLDEVRKQPVPPVRRASVVSDAGIEQVVRKQPVPPVRRASI VSDVGVEEVMKQPVPAAIRASVVSVSDPGVDEVRKQPVPPVRRASVVSVSDTGVDKVKKQ PVPPARRASVVSVSDTGVDEVRKQPVPPARRASVVLVSDTGVDEVRKQPVPPVRRASVVS VSDTGVDEVRKQPVPTVRRASVVSDAGIDQVVKQPVPPARRSSIVSDAGVDQIVRSKKKM DIEIDHQEKQPVKSMVKETEIEQRNQQPVRSTVQETEKPKMVEDDNQLHISEDESFTEAH TQVTVNQKTSKPVVAVAGVPKGLQMTRQVDEIALDSVEDEHEMLEAAIKIQAAFKGYKTR KDMRPIFKQVFKNQSAETNGTIQLECKVEGKLNAVRWLKNSQEVIGDQRHRMNTSEDGVC TLVIINMSAIDTGVYTCEVVNTFGVSSYNGNITVGEPQMPPSSTQRPAAPSQPSTPSVHP VLASIGPLQPVQTSTPGKETVDSVECEGISLWQTYNLTKEDPRMTLQERRRASLIAASSM SSPSDYDTAPDFIEPADIIPKDHPREKEAIKSQDQLSNKEDEEQKVTSQPPRRFKAKVPD AMLRTPSPKHYHAHTPAALTGSGSESDCDEDRIETFDIYVARANCSPQQGGNKESFVLKE GQYVEVLDSVHPEKWLVRTKPSKTTSSRQGWVSPAYLEKKRKETFPQMRTPQQELDVPWS TGENYRRTLSQLIQGLIDGEEEFVKEMKEFMSHHLHHLDTSTRVPISIINQKETIFRNIK DIMALHERSILPCLSECSTDDDVAMRLVKHAVDFEKYLQYMVGQSQAEACVTDKTIQQYF KQNTETHPEHPETAVLDVITFLQRPVERIQTYQALLKELIKNKAKCAKSCLLLEDAFSMV SCLPWRSDNLHQVSLIENYPAPLTALGEPVRQGPFTVWEESPEIKTSSRGHQRQVFLFKD CVLLCKLKRDPGMNSDTYAFKNKMKLNDVEVKETVGGEEKSWGLWHEHRGSVRRYTLQGR SAVLKLSWLKDLRELQQLSSLTASSPPEFEVLLADCTTKIGQTIKLACKVTGTPKPVVSW FQDGLALEDGPHHIITADRAGTCCLIMDGVTPEDSGQYLCYASSSVGHASTLAKIVVDAP PRFLTRLQSACLLEGEDIKFSCSTHSTPLPRVSWFKDGRELTDQRKYHIESDARSGILTL TIMNPGETDLGQYKCELWNKLGSAKSKAEMCSAFAQVMDSEPDQPQAILIQDSDSEGWST AMVKQWLQTDFHPTSVVKMLFQPGYPQPAEGSQEERDPSARGHVEAPQFPTELEERPELE EELYVPEAIEEMPTAPPSIQVPVEDLCVEPGQSATFTIIITGRPTPEIQWYKDGEELLAT ENVEVVQNGARCSLTVLCPESEDGGIYTCWAYNDLGHTSCQARLTVEEGPLESQEREVEL GKRRKLLSVYDVHEEIGRGTFGVVKRVTHRRTGEGFAAKFLPLRSSTRTRAFQERDLLSR LAHPRVACLLDFFSTRRTLVLVTEACSSRGLLDHLLSKGSVSEREVQMYIQQILEGVGHI HSMNILHLDINPDNILMVFPPREEIKICDFGFCQEMDTSRHQYSQFGTPEFVAPEIIHQD PVTIASDIWSIGVVAYLCLMCRCPFMGETDRATLMRVGEGTLNWDAPDLTYRSTGAQGFL RTVLQPDPVKRPTAFECLGHKWFQGEHEDETDDINTRALKVFISRRKWQRSLTCLGSVLI LKPIPELLDAPLRETSITAPRDPHEPSSTSMSSGSSSEYDEADAWDFFHHCTTADEDEDE EEEEFDPLMERARIPEPFAKLKLEEEEEGTMEEEDEEEEEEEMGGQMSVLERSLSRQSIG SSDASQQPTPQRERRVSRESSPSLYLSEGDDGSASGSEGGCIARSSLIRSTFYNSSAQLS PMSARHMTLRDKFQAKKQERGRKPLRRSLSSRLNEPLIEYVEDEGETNIGQRRGSLQSSM LKSCSFDSGVSLSHNAPPQRRSKSLDEYSRRSPGSAKRREEESALNLKEDFTDKEEEEKS LDIPPLQVRGRRGSVAVAPKQLTARLQELCAKSPHAGPEKSLRPEEEAGNLAGSQYSLAE SLILEHGSEGSSRLDSCEGLSHGYPAATQRGRAGDEYDDQEEPLITMSPCSLLQGSEAVE ANKEPQCRSGQLQIPPRRTTHPNQNSTARNNGKVEKTILPVKPSPSLSFKAPERPSRSSD TEARLQRHSSTPALQAKPPTGKSPRMSPKVGLMNLLRRQSWAGHSYSQLEGTEQGPTLGE LEPKTPTMSLRKKMRASASSLTKLFTKSSSKEDLTKGGPIVKGSSPAPPEQKASAGLESA KKKSTLFSFRIPKIPAFKKNKEMLIHLTRPDVHQLEAGGFLLVWRPVQSSDPVVYCVQYS TDGGEWKLLCEEVTDSCYVVKDLLRGAGYVFRVGCITKKGAGPFSDPSPPVVMATHPKET HIPLIQTEYPGSKGSGSRGQPSHKTYSFLAEINRGRFSVVTQCQDGQSQQLFAAKITPYR PENRALVLREYQLLKKLNHPHLVQLHTAYITPHCLVLIQELCAGRELLYNLTERDLYAEL HVAELLAQILSAVDYLHSRRVVHLDLKSDNMLVTDRNVLKIVDLGSAQSFTPGQTLNIED IPGQEKETPSSASPQTTGRNRMADGAPEILDGQGVGPETDIWAIGVLAFIMLSADSPFHS DLNWERDRNIRKGKIQFGRCYPGLSEGAINFIKNTLSIKAWERPSAAECLQNPWVRGERA PSKHRDSILCFSTDKLQAFLTEREVKRDQVRTKLQGPFFQ NT seq 19923 nt NT seq  +upstreamnt  +downstreamnt atgggagacaagtctgggagcaaagtagctgctgcaaagaaccagatccatctccgggta gtgaaggggctggaggatgtggatgtgcgtgagagggagggctgcacgttcgaggtgacc ctcaacctgtcctacatagcgggcacgtggaccaaggacggggtcaggctacaagccaag cccacctgtcgcatcgctgcccataagaataaacacactctcaccttcacccgggtcacc gtaggagacactggcctattctccttccagactgatgggacccaaaactggatccaaacc tcaggccaactcactgtcatagccagagacatacagattgtgaaggagttggaagacgag gaagtgactgagaggcagagtgtgaccttcctgtgcgaagtcaactgtgaggacgtggac gggcgttggtacagcgacaacaccaggatcaaacacggagacaacgtcaagatcaggcac gagggtaaaactcacaccatgtgcttcaagtctgtaaggccagcaaacgctggggagatc aaattcactgcagacagggtctcctgctatgcaactctcacggtaaaagagctgcctgtg cagatagtgaagcctctgagagtgaagattgctatgtacaaacacaaaggactgctggag tgccaggtgtccagggccaacgccctggtcaggtggttcaagaacaggagtgagatccaa cccagcaagaagcaccagattgttagcgacgatgtctacaggcagctgcacattgatgac gtggcctcgtcagacgaggacacctacacctgtgatgctggcgatgacaagacctcctgc caactactagtggaggagcaggcgatcagcatagtgcaggggctaaggtctgtggaggtg accgagcccagggaggccctgttccaggtggagaccagcctgagggcagggaggccccca aagtggaccctggacggagaggtcctgatggacgggcctgaactgagcatagaccggcag ggcacactgcacaccctctgcttcatcagcacggacagctctatgaccggccctgtgcag ttcaacgccgggaagagccgctccaccgcacagctcaccgtgaaggaacgccctctgaaa gtggtccagcccatgccagacgtggaggctaaagagaacagctcggtcacactgaggtgt cagtttgccccctcccccagggtggtgcgctggtacaggggccgcactgccctgcagaca tccagcaagtacagcatgaggacggagaagaaccaggcagagctgaccatccagggcctc aaggagaccgacactggccagtacagctgcatggctggagggtcaaagagcacagccaag gtcgatgtgcaaaggctgaagatcgtaaggcacctggagcacgtgaaggtggaagaggat agcaacgccacattcacatgtgaactcaactacgtggtagccaatgtgcagtggcttctg aacgacaaccacctcaacgccaacactgttaccaggattcagaacatgggcaccattcac agcctcaccatcaaaaatctccgcccacaggagagcagggtgaccttcaaggctggcctt ctcacagagtccacctccctcaaggtcaaagaaaaaccagcagtgttcctcaggtctcta gaagacatgtcaggggaggaggaggggaaggtgtgtctgcagtgtgagacctctaaggaa atggccacccccgtctggaggaaggatggtacggtcctggacagcagtgacaaatatgag ctgctcatgtttgggaagtccttaacgctcatcatccatagtctgagtaaggatgatgca ggccactacagctgtgacttgggcaccagccagaccaaggccaaggtcactgtacatgac attcacatcaccatcgcccagcgtatgaagactgtctctgttctggagggcgagagctgc agtttcgagtgcatcctctctcacgatgtcatcgacgagccctcctggaccctgaacggt cgacttgtgatcagcaacagccgcatccagatcgtaaacaagggtcgcaaatacaagatg accatcagagacgcaactgtgactgaagccggggacgtaatcttcttcatcaaagacctc agctgcaggaccatgctgtttgtcaaagagaagccagtgcatgtgttcagggacatgatg agcattaaagccaccccaggggagaacgctgagctgagctgtgagatcaccaagcctgag gccttcatccgctggctgaagaatggccatcagatcaggcacagcccccccaagtacgag atcagtgtggaggaccacctggtacggctggttatcacgaacacctgcatcagagactct ggggagtactgctgtgaggctgacggcattgccacccgggccaagctggaggtcagagag ctgcagcacacatttgctcgggagctgcgggacacacgggccgaggagaagagcaaggtg atgctggagtgcgagacgagactgccggccaagcgggtgacctggctgaagggcatggca gagctccgggcgggtaggaagtatgtgatgaagcagaagggagtggtcctctatctcacc atcagctgcctggagaaggttgacaccgacgtgtacacctgcgatgttggcaccatgcag agccgggcgctactgaccgtgcatggtcagaaggtgttgattttggacgagctggaggat gttgagtgtctggagaatgacacagtgatgttcaggtgtcgtatctgtcccagcgattat gttggggtcaagtggtacctggatgagaccttactgtacaccaatgagctgaatgagatc caagtgatcccggggggctaccacagcctcacgttcaaacaactggctcgtaaagactcg ggcaccatctcctttgaggcaggcgacaagaggtcctacgcctcgctgcttgttagagag agacgtcccaccatcaccaaagcattggaggactgtgaggccattgagggaggcggtttg gtgctggtgtgtatcacctctaagccatgccacatcctgtggtacaaagatggctgcctg atgtggatttcctcgaggtaccacgtcagtcgctcaggtaacgaggccaggctgaccatc agggaggtcagtaacagcgatgctggggtgtacgagtgcagcgctgggtcggtcagcacc aaggctgtcgtcactgtaaaagccattccagctgagttcacccagccgctgcagagcatg gaggtaaaggagggggaggatgtgaccctttcctgtgagttctccctgccgggggttgcg ttccactggaagaggggcttggagaccctcagagctggagagaggtacctgatgaagcag aagaggtccttcatctctttgaccatcactggcccgaagcctcaggactcaggagattac acctgtcagtgccgagaccacagaaccacagccagcctcacagtccacgccatccccatc tccttcacacaacagttgaaaaatgttcaggccgaggagggcaacagtttaacgttgcgc tgtgagctttctaaaccaggagtccctgtggagtggaggaaaggggaggagctgttaaag aatggagtgaagtttcagataaggaagagagagaccatattggaggttcagatatggaaa actgtgcctgaagacagtggagtctacagctgtgagtgtgcggaccaaaagaccacagcc accgtcaaaatcagcgccctgcctgttaccttcaaacaaaagctgaggaacgtgcatgtt gaagaggggaacaatttggtgttacactgtgagctctctaaaccaggagtccctgtagaa tggatgaggggaggagaggagctgctgaacaatggagagaggtttcagataagacagaga gagttggtgaatgaactgaagataatagatgccaaacctgaagacagcaatatctacacc tgtgtttgtggcaatgtggaaaccacggccggtgttacagtcacagcaattcccatcact ttcaagcaaaagctgaggaacctgcagactgaggaagggaacaccatctcgctgcactgt gagctgtctaaagcaggggtgccagtggagtggagattgggaggagagaggatactgcag aatggagacaaataccagatcaagcagacagactcagcactggaactcctcatcagggag gctctgccagaggacagtggagtctacagctgtgtgtgtcgagacaagaagaccaaggcc actgtcaaagtcattgctgtacctgccaccttcaaagtgggtctgaagaaccaggaggcc ccagaggagggcagcataaccctgcactgtgagctgtctaaggctggggtctcagtggag tggagaaggggggagacagaactgtcccaagacctgtctggaggaaagtaccagatgaaa ctggaggggaaaatagccgagatgaccattaccaatgtcaaaccggaggacatagggaag tacagctgtgtcactggagaccagaagaccaccgctgaagttaaagtgcaggctctccct gtaatgttcacacaagaggtccagaacgtggtgatcaaagagggggacagtggggagttc tggtgtgagctctccaagcctggtgacccagtggactggaggaggggcagagtcctcctg aagtctggagacaaatatgagatgaggcaggagggacgcatcactaaactgctcatccat aacgtggaggagagggatgctgggaaatacacctgtaagagtcgagatgccaagtcaact gctgaactgaccgtgacgggcccaccccccactttcaaagaacagctgaggaacgtggaa gttgaggagggtaagactgtgacgctacactgtgaactgtctaaagcagcagcctcagtt gagtggaagaggggagcaaagctgttgacgaatgtagccaagtaccagatgaggaagaaa gatttactggtggaattgaagattatcgacgcgaatctggaggacagtggggtctacgcc tgtgtttgtggtgaacaaaagaccacagccactgttacaataaaggctcgcccggtcaca tttatagaagagttgaggaacgttcaggttgaggagggcaacactgtgacgttgcgctgc gagctctccaaaccagggatgtcggttgaatggaggagaggaacagctcttctgcagaac ggagagaagtaccagatgaagcagaaagatgcaacgttggagctggtcatcaggaaaacc ttggccgaggacagtggtgtctacagctgcgtgttggaagaccagcaaaccttcgccacc atcattatcactgccatcccagccactttcaaacagacgttgaaaaaccaagaggctcta gaagagggaagcgtgacgttgcgctgtgagctgtctaaatcgggggtctctgtggtgtgg ctgaagggagaggagctgctgagggaaggtgagcggcaccagatgaagcaggagggcagg accgtggagatggtcatcaggaatgcagtccttcaggatgctggggagtacagctgtgtc acagcctgcaacgtcaagacgacagctgatatcaaagttagggctctccctgtaatgttc acacaagaggtccaggacatggtgatcaaagagggggacagtggggagttctggtgtgag ctctccaagcctggtgacccagtggactggaggaggggcagagtcatcctgaagtctgga gacaaatatgagatgaggcaggagggacgcatcactaaactgctcatccataacgtggag gagagggatgctgggaaatacacctgtaagagtcgagatgcccagtcaactgctgaactg accgtgacggctcctcccgtcacgttcaaggtgaagttgaagaaccaggaagtcgaggag gagaacagcgtgacgttattctgcgagctctctaaaccaggactgacggcagagtggaga aaaggagaggagctgctgaagaacggagtaaagtaccagataaagaagagagaggcaacg atggaactgacaataaggaatgcagtgctcgaggacaccggattctacagctgtgtttac gcagaagccaaaaccaccgccactgtcaacatcacccccattcctgtcaccttcaagatg ggtcttaaaaaccaggaggcctcagaggggggcatcgtgaccttgcgctgtgaactgtct aaagctggggtaccggtggagtggtggaaaggggaggaggaggtgagccctggaggaagg taccagatgaagctggagggaaagatagcagagttgcacattaaaaacatccagccagag gacgtgggggagtacagctgtatattcgaagatcagaaaaccactgctgaagtcaacgtg agaggtacagtatgttactgttgtctggctgtcattttgtgtttgttggacatgaaatgc tcatttaccaagaaacaaagagttgatgtatggacctccccagcaactgcaccaaagtgt tatagaatacgcaataagcaagaggtcaatgcaattgctctctctaggaataaaacaata cctgctgcctcagtgttctttgagaaggagctggagagcaatgtggtgatggaggggaag tccatggtcctctcctgtgaggtctccagtgccactgtccccgtcacctggaagaaggat gcctgcctggtcacagatggggagaggttcattgtaaaaaagaaaggtcccgttcacacc ctggagatcgagaagctgagtctggaggatgccggggagtacagctgcatcactagggga aagaagaccacagccatgctggttgtgaaagagcgtgtgaaaatattgtccggactgaag gacatgaaagtcacagccgggcaggacgcagtgtttgtgtgtgagctgtcccacgctgag gtgagtgaaggcgagtggtggctgggctccagcccactgcagaagaacgaaatgaaccag atgagctttgagggccaccagcactgcctggtcttgaccatgaccaccccggaggagacc gggaccgtggccttcgtggttggggaggagagaacctctgcccaactgctagttgtcccc aaacccaaagtacacattgagaagaagccccaggacattgacatcatggaaggggagaca gccaccttatcctgtacgacctctgacctcattacccctgtcacatggagaaggaacagc atgcccctcctgaacggagacaagtatgagacgcgtaagaagggcaagctcaacctcctg ctcatccatgagacggaaccagaggactctgggatatactcctgtgacactggagacatg cagagcggtgccaatctgacggtcaatgagctaccaccgtacttcgaggaggagctgcag tgtgtggaggctgaggaagggggcacagcctttctgttttgtgagctgtctaagcccgga gtcccaatccagtggaggaaaggccggctgcctctccggcccaacaggaagtaccagatg aagcaggacggctgcgtgtttcagctacacatcctggagctgaagtccgaggacagtggc agctactcgtgccaggcaggctgtgtggagaccaccgcctctgtgtctgtgaaagttaaa gtactcattgagaagaagccccaggacaccgtcatcatggaaggagagactgccacctta tcctgtacgacctctgacctcactacccctgtcacatggagacgcaacaacatcaccata ctgaacggagacaagtatgagaaccgtaaggagggcaagctcaacctgcttctcatccac aatgtggacccagatgactctgggctatactcctgtgatactggagacatgcagagcagc gccaaactgactgtcacagagctggcaccatgctttgaagaagagctgcaggctgtggag gctgaggaaggaggcacggccttcctttcctgtgagctgtctaagcccggagtcccagtc cagtggagtaagggccggctgcctctcaggcccaacaggaagtaccagatgaaacaggac ggctgcgtgtttcagctacacatcctggagctgaagtccgaggacagtggcagctactcg tgccaggcaggctgtgtggagaccaccgcctctgtgtctgtgaaagttaaagtactcatt gagaagaagccccaggacaccgtcatcatggaaggagagactgccaccttatcctgtacg acctctgacctcactacccctgtcacatggagacgcaacaacatcaccatactgaacgga gacaagtatgagaaccgtaaggagggcaagctcaacctgcttctcatccacaatgtggac ccagatgactctgggctatactcctgtgatactggagacatgcagagcagcgccaaactg actgtcacagagctggcaccatgctttgaagaagagctgcaggctgtggaggctgaggaa ggaggcacggccttcctttcctgtgagctgtctaagcccggagtcccagtccagtggagt aagggccggctgcctctcaggcccaacaggaagtaccagatgaaacaggacggctgcgtg tttcagctacacatcctggagctgaagtccgaggacagtggcagctactcgtgccaggca ggctgtgtggagaccaccgcctctgtgtctgtgaaagttaaagtactcattgagaagaag ccccaggacaccgtcatcatggaaggagagactgccaccttatcctgtacgacctctgac ctcactacccctgtcacatggagacgcaacaacatcaccatactgaacggagacaagtat gagaaccgtaaggagggcaagctcaacctgcttctcatccacaatgtggacccagatgac tctgggctatactcctgtgatactggagacatgcagagcagcgccaaactgactgtcaca gagctggcaccatgctttgaagaagagctgcaggctgtggaggctgaggaaggaggcacg gccttcctttcctgtgagctgtctaagcccggagtcccagtccagtggagtaagggccgg ctgcctctcaggcccaacaggaagtaccagatgaaacaggacggctgcgtgtttcagcta cacatcctggagctgaagtccgaggacagtggcagctactcgtgccaggcaggctgtgtg gagaccaccgcctctgtgtctgtgaaagttaaagtactcattgagaagaagccccaggac accgtcatcatggaaggagagacggccaccttatcctgtacgacctctgacctcactacc cctgtcacatggagacgcaacaacatcaccatactgaacggagacaagtatgagaaccgt aaggagggcaagctcaacctgcttctcatccacaatgtggacccagatgactctgggcta tactcctgtgatactggagacatgcagagcagcgccaatctgactgtcacagagctgcct ccatactttgaggaggagctccaggctgtggaggctgaggaaggggaaacggccttcctg tcctgtgagctgtctaagcctggagtcccagtccagtggaggaagggccggctgcctctc aggcccaacaggaagtaccagatgaagcaggacggctgtgtgtttcagctacacatcctg gagctgaagtccgaggacagtggcagctactcctgccaggcagatggcgtggagaccacc acctctgtgtctgtgaaagttaaagtactcattgagaagaagcctcgggacaccgtcatc atggaaggcgagacggccaccttatcctgtacgacctctgacctcactacccctgtcaca tggagacgcaacaacatgcccctactgaacggagacaagtatgagaaccgtaaggagggc aagctcaacctgcttctcatccacaatgtggacccagatgactctgggatatactcctgt gacactggagacatgcagagcagcgtcaatctgactgtcacagagctgcctccatacttt gaagaagagctgcaggctgtggaggtagaggaaggaggcacagcctgcctgtcctgtgaa ctgtctaagcctggagtcccagtccagtggaagaagggccggctgcctctcaggcccaac aggaagtaccagctgaagcaggacgactgtgtttttcagctacacatcctggagctgaag ccagaggacagtggcagctacacgtgccaggcaggtggtgtgaagaccacagcctctgtg gcagtaaagcctctcccagccaagactgaacctcccaagacaatgcctcccacaaaggct cccacgaaggctgcctctcccacacctccaccagggccaaagaaacagggcatgatctgg gcatccattgtggggtcagagaaagacctggagcctgaggcagggacagtggtagaccta catgagaaacagtcagtaaggtctataggtaaggagactaaagtagaccagcaggagaaa cagcaagtcaaacagacagtaagagctatggtgagggacacagaggaaaaaaagccattg aagtctatggttaaagagattgaagtagaccacatggtgaaacagccagtgcccccagcg agacgagcatctataatgtcagatactggaatagaccaagtggtgaaacaaccagttcca ctagtgagacaagaatctataatgtcagatactggaatagaccaagtggtgaaacaacca gttccactagtgagacaagcatctataatgtcagatactggaatagaccaagtggtgaaa cagccagttccaccagtgagacgaccatctataatgtcatatactggggtagacgaggtg aggaaacagccagttccaccagtgagacaagcatctgtagtgtcagatgctgggatagac caagtggtgaaacaaccagttccaccagtgagacgagcatctatagtgtcggatgttggg gtagatgaggtgaggaaacagccagttccaccagtgagacaagcatctgtagtgtcagat gctgggatagagcaagtggtgaaacaaccagtaccaccagcgagacgagcgtctgtagtt tcagtttcggatactggggtagatgaggtaagaaaacagccagttccaccagtgagacga gcatctgtagtgtcagatgctgggatagagcaagtggtgaggaaacaaccagttccacca gcgagacgagcatctgtagtttcagtttcagatactggggtagatgaggtaagaaaacag ccagttccaccagtgagacgagcatctgtagtgtcagatgctgggttagacgaggtgagg aaacagccagttccaccagtgagacgagcatctgtagtgtcagatgctgggatagaacaa gtggtgaggaaacagccagttccaccagtgagacgagcatctatagtgtcagatgctggg ttagacgaggtgaggaaacagccagttccaccagtgagacgagcatctgtagtgtcggat gctgggatagagcaagtggtgaggaaacaaccagttccaccagtgagacgagcatctata gtgtcagatgttggggtagaagaggtgatgaaacagccagttccagcagcgatacgagcg tctgtagtttcagtttcggatcctggggtagacgaggtgaggaaacagccagttccacca gtcagacgagcatctgtagtttcagtttcagatactggggtagacaaggtgaagaaacag ccagttccaccagcgagacgagcgtctgtagtttcagtttccgatactggggtagatgag gtgaggaaacagccagttccaccagcgagacgagcgtctgtagttttagtttcggatact ggggtagacgaggtaagaaaacagccagttccaccagtcagacgagcgtctgtagtttca gtttcggatactggggtagatgaggtaagaaaacagccagttccaacagtgagacgagcg tctgtagtttcggatgctggcatagaccaagttgtgaaacagccagtgccaccagcgaga cgatcatctatagtgtccgatgctggggtagatcagatagttagatctaaaaagaagatg gatatagaaatagaccatcaagagaaacagccagtgaagtctatggtgaaggagacagag atagaacagaggaatcaacagccagtaaggtctacagtgcaggagactgaaaaacctaag atggtggaggatgataaccaactccatatctcagaggatgagtccttcacagaggcccac acccaggtaacagtcaaccagaagaccagcaagcctgtagtcgctgttgctggagttccc aaggggctacagatgactcggcaagttgacgagattgcacttgacagtgtcgaggatgaa catgagatgttggaagctgccatcaagatccaggcagctttcaagggatacaagacccgc aaagacatgcggcccatcttcaagcaggtgtttaagaaccagagtgctgagaccaatggt accatccagctggagtgtaaggtggaagggaagctcaacgcagtacgctggctgaagaac agccaggaggtcataggagaccaacgccaccgcatgaacacctcagaggatggcgtctgc acactggtgatcatcaacatgtctgccatagacactggggtctatacctgtgaggtggtt aacacgtttggtgtgtcctcatacaatggtaacattactgtgggtgaacctcaaatgcct ccatcttctacccagaggcccgcagccccatcccagccctccaccccttctgtgcatcca gtcctggcctccattggccctctccagccagtccagacctccacccctgggaaggagact gtggattctgtggagtgcgaggggatctccctgtggcagacctacaatctaaccaaggag gatccccgcatgaccttgcaggagaggaggagggcctcccttattgccgccagctctatg tctagtccctctgactacgatacagctccagatttcatagagcctgctgacataatcccc aaagatcaccccagggaaaaggaagccattaagtcacaggaccagttatccaataaggag gatgaagaacagaaagtgacgtctcaaccacccaggcgttttaaggccaaagtacctgat gccatgttgaggactccatcccccaaacactatcatgcccacacacctgctgctcttaca ggctctggctcggagtcagattgtgacgaggatagaatagagacatttgatatatacgtg gccagagctaactgcagtcctcaacaaggtggcaacaaggagagctttgtgttgaaggag ggtcagtacgtggaggtcttggactctgtccacccggagaagtggctggtccgcaccaag ccctccaagaccacctcctcacgccaaggatgggtctctcctgcatacctggagaaaaag agaaaggagacattcccacaaatgagaacaccacaacaggagcttgatgtaccatggtct acaggggagaactacaggagaaccctaagccaattaatccaggggctgattgatggggag gaagagtttgtgaaggagatgaaggaattcatgtcccaccacctgcaccacttagacacc agcactcgtgtccctatcagcatcatcaaccagaaagaaaccatcttccgcaatataaag gacatcatggctttacacgagagatctattctgccctgtctgagtgagtgttctactgac gatgacgtggccatgcgtctggtcaaacatgcagtggactttgagaagtatctgcagtac atggtgggccaatcacaggcagaggcctgtgtcactgacaagaccatccagcagtacttc aagcaaaacacggaaacacaccctgagcacccggaaactgcagtcctggatgtcatcacc ttcttacagagaccagtggagaggattcagacctaccaggccttgctcaaggaactgatc aagaacaaggctaagtgtgcgaaaagctgtcttctactggaagatgccttctccatggtg tcctgtctgccctggcgctctgacaacctacaccaggtgtctctaattgagaactaccct gccccactcactgcactaggagaacctgttcgccagggtcctttcactgtgtgggaggag tctcccgagatcaagacgtcctccaggggccaccagaggcaggtgttcctcttcaaggac tgtgtcttgctgtgtaagctcaagagagaccctggcatgaactctgacacctacgccttc aagaacaagatgaagctgaatgatgtggaggtgaaggagacggtggggggagaggagaag tcctgggggctgtggcacgagcaccggggctcagtgaggaggtacacactgcagggccgc tccgccgtgctcaagctgtcctggctcaaagacctgagagagctgcagcaactctccagc ctgactgccagcagtccaccagagtttgaagttctcctggctgactgcaccacaaagatc gggcagacaatcaagctggcctgcaaagtcacaggaacacccaaaccagtggtcagctgg ttccaagatggcctggccctagaggatggcccccaccacatcatcactgcagaccgggca ggcacctgctgtctcatcatggatggggtcactcctgaggactctggacagtacttgtgc tacgcttccagctctgtgggccatgctagcacactggccaagatagtggtggatgcaccc cccagattccttaccaggctgcagagtgcatgtctgctggagggagaggacatcaagttt agctgttccacacacagtactcctttaccccgagtcagttggtttaaggatggcagagag ctgacagaccagaggaagtaccacatagagagtgatgcccgcagtgggatcctcacgctc accatcatgaaccctggagagacagacctgggacagtataagtgtgagctgtggaacaag ttgggcagtgccaagagtaaagcagagatgtgctccgcctttgcacaagtgatggacagt gagcctgaccaaccacaggccatcttgatccaagactccgactcagagggctggtccact gccatggtgaagcaatggctgcagacagacttccaccccacctctgttgtcaaaatgctc ttccagcctggataccctcagccagccgagggtagccaagaggaaagggacccttccgcc agaggacacgtggaggctccacagttccccactgagcttgaggagagacctgagcttgag gaggaactttatgttcctgaggccatagaggaaatgccaacagctcctccctccatccag gtgccggtggaggacctgtgtgtggagcctggtcaatcagctaccttcaccatcatcatc acaggaaggcccacccccgagattcagtggtacaaggatggagaggagctgttggccact gagaatgtggaggtggtccagaatggtgcccgctgctctctgactgtgctgtgcccggag agtgaggatggtggcatctacacctgctgggcctataacgacttaggacacacctcctgt caggctcggctgacagtggaggagggtccactggagtcgcaggagagagaggtggagctt gggaagaggaggaagctgctgtctgtgtatgacgtccatgaggagattgggagaggcacg tttggggtggtaaagcgggttacccacaggaggacgggcgagggctttgccgccaagttc ctgcccctgaggagcagtacgaggaccagggcgttccaagagagggacctgctctcccgg ctggcccaccccagggtggcctgtctgctggacttcttctctacacggaggaccctggtc ctggtcaccgaagcctgctcttctcgtggtctccttgatcatttgctgtcgaagggatca gtcagcgagagagaggtgcagatgtacattcagcaaatcctggagggagttggtcacatc cacagcatgaacatcctacatctggacatcaatccggacaatatcctgatggtgtttcca cccagagaggagatcaagatctgtgactttggcttctgtcaggagatggacacttccaga caccagtacagccagtttggcactcctgagtttgtggcccctgagatcatacatcaagac cccgtcactatagcaagtgacatctggtccattggtgttgtggcctatttatgtctgatg tgccgctgtccgttcatgggggagacggaccgggccactctgatgagggtgggggagggg acactgaactgggacgcacccgacctcacctataggagcaccggtgcccagggcttcctc cgcacggtcctgcagccagacccagtaaagcggccaactgcatttgagtgtctggggcac aaatggttccagggtgaacatgaggatgagactgatgatatcaatacaagggctctgaaa gtcttcatctcaaggagaaaatggcagcgttctctgacctgcctgggctcggtgctaatc ctgaagcccatcccagagctgctggatgcccctcttcgggagacctccatcacagcccct cgggacccccatgagcccagcagcacctccatgagcagcggctcctcctctgagtacgac gaggctgatgcctgggacttcttccaccattgcaccacagctgacgaggatgaagacgag gaggaggaagaatttgaccccctcatggagagagccaggatccctgagccctttgccaaa ctgaaattggaggaagaggaggaggggaccatggaggaggaggacgaggaggaggaggag gaggagatgggaggacagatgagcgtgctggagaggagccttagcaggcagtctataggg tcctcggatgcgtcacagcagccgaccccccagagggagaggagggtcagccgagaaagc agcccgtccctatacctctccgagggggatgatggctccgcgtccgggagtgaaggaggc tgcatcgccaggagcagcctgatccgcagcactttctacaacagctccgcgcagctctcg cccatgtccgctcgccacatgaccctcagggacaagttccaggccaagaagcaggagagg ggccgcaagccgctccgcagaagcctctctagccgcctcaacgagcctctcattgagtat gtggaggacgaaggcgagaccaatatcgggcaaaggcgagggtctttgcagtcgtccatg ctcaagtcctgctcctttgacagcggggtcagcctctcgcacaatgcaccaccgcagagg aggagcaagtcgttggacgagtactcccgacgctcaccaggatccgccaaacgtagagaa gaggagagtgctttgaatcttaaggaggatttcactgacaaggaggaagaggagaagagc ttggacattccccctctccaagtgagaggtagaagaggttcagtggcagtggctcccaaa cagcttacggccaggcttcaggaactgtgtgcaaaatcgccccatgctggtccagagaag agcctcaggccagaggaggaggcggggaacctggctggctctcagtactccctggctgag tccctcatcctggagcatggctctgagggctccagcaggctggactcttgtgaggggctg tcccacggctaccctgcagccacacaaagagggagagcaggggatgagtatgatgaccag gaggagcccctgatcacaatgtccccctgctccctgctccaggggtctgaggctgtggaa gctaataaggagccccagtgccggagcggccaacttcagatcccaccgagaaggacaacc caccccaaccagaactcaacggccagaaataatggtaaggtagagaagacgatcctgccg gtgaaacccagccccagcctgtccttcaaggccccagagagaccctcgaggtccagcgac acagaggcacgtctccagaggcactcgtccaccccggccctccaggccaaaccgcccacg gggaagtctcccaggatgtcacccaaggttgggttgatgaatctgttacgtaggcagtcc tgggcggggcattcctactcacaactggagggcacggagcagggacccacgctaggggaa ttggagcccaaaacccccaccatgtcactcaggaaaaagatgagggcatcagcctctagt ctcaccaagctgttcaccaaatcgtccagcaaggaggacttaacgaagggagggccgatt gtaaagggttcctctcctgctccacctgagcaaaaggcgagcgctggcttggagagtgct aaaaagaagtccacattattttcatttagaatacctaaaatacctgcattcaagaagaac aaagagatgctcatccacctgaccaggcctgatgtgcaccagttggaggcaggtggattt ctgctggtatggagaccagtgcagtccagcgacccagtggtttactgtgttcagtacagc acagacggtggggagtggaagctactgtgcgaggaggtgacagacagttgctacgtagtg aaggacttactcagaggagcaggatacgttttcagggttggctgcatcaccaagaagggg gcaggacctttcagtgacccttcaccccctgttgttatggcaacccatcctaaagagacc cacattcccctcatccagaccgagtacccaggatcaaagggcagtgggtcaagaggtcaa cctagccacaagacctacagcttcctcgcagagatcaacaggggtcgtttcagcgtggtg acccagtgtcaggacggccagagccagcagctgtttgctgccaagatcaccccttacagg ccagaaaatagagctctggtgctcagggagtaccagctgcttaagaagctcaaccacccc cacctggtgcagctgcacacggcctacattaccccccactgcctggtgctcatccaggag ctgtgtgctggcagagagctgctctacaacctgactgagagagatctttatgctgaactc catgtggcagagctgctggctcagatcctgagtgctgtggactacctgcacagccgccgc gtcgtccacctggacctcaagtcggacaacatgctggtgacggaccgcaacgtgctgaag atcgtagacctgggctccgctcagtctttcacacccggacagacactcaacatagaggac attccgggacaagagaaagagactccatcgagcgcctctccacagacaacgggcagaaac agaatggcagatggggctccagaaatcctcgacggacaaggagtcggacctgagaccgac atctgggctattggggttttggcttttataatgttgagtgcagatagcccgttccattca gacctcaactgggagagggacagaaacatccggaaggggaagatccagtttggccgctgc taccctggcttgtcagagggagcaatcaacttcataaagaacacactgagcatcaaggcc tgggagagaccctcggcggctgagtgcctccagaacccgtgggtacggggcgagcgggcc ccctccaaacacagagactccatcttgtgtttctccactgacaagctgcaggctttcctc acggagagagaggtgaaacgagaccaggtccgcaccaagctgcaaggcccgttcttccag taa

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