Oncorhynchus mykiss (rainbow trout): 110529177 Help Entry 110529177         CDS       T07259                                  Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism omy  Oncorhynchus mykiss (rainbow trout) Pathway omy04020   Calcium signaling pathway omy04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:omy00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     110529177    04020 Calcium signaling pathway     110529177  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:omy04040]     110529177 Ion channels [BR:omy04040]  Voltage-gated cation channels   Ryanodine receptor    110529177 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 EF-hand_1 Motif Other DBs NCBI-GeneID:  110529177 NCBI-ProteinID:  XP_036840550 LinkDB All DBs Position 8:complement(8010070..8255412) Genome browser AA seq 4891 aa AA seqDB search MAEGGEGEDDIQFLRTDDEVVLQSVATIQKENRKFCLSVEGLGNRLCFLEPTSEAKYVPP DLCICCFILEQSLSVRALQEMLAHTVPNNEGKADHEQWAAQGGGHRTLLYGHAILLRHSF SGMYLTCLKTSRSLTDKLSFDVGLQEHSIGEACWWTIHPASKQRSEGEKVRIGDDLILVS VSTERYLHLSISNGSFQVDASFMQTLWNVQPTRSGSNVAVGFLCGGHVMRLCHGHDESLT IPGSEASEMEQRIVNYEMGKGTSKARSLWRLEPLRIGWSGSHIRYGQAFRLRHLSTGHYL ALTEEQGLVLQEREKSDTKSTAFCFRATKEKIESGTKNRDIEGMGVAEIKYGDSACFVMH VATGLWLSYQTPDAKASRIGPLKRRACLHAEGHMDDGLTLQRCQHEEARAVRIIRNTTVL FSHFIKGLDSIGRDKNVAVSLPNFDEVLQTLDDLIEYFKQPDSELEHEEKQTLLRSLIKR QDLFKEEGMLTLLVMCIDRLNLYNSAAHFGEHAGEEAGAAWKSILNLLYQLLASLIKGNR NNCTQFSRNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHG RNHKILDVLCSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGVAE GSAQYKKWYFELMIDQVDHYVTSEPSHLRVGWASTKGYAPYPGAGEGWGGNGVGDDLYSY SFDGLYLWSGRIPRAVASINQHLLNNDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTD GFFFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMRVEAVKEYKRDHG GVRDLLGTTQILSQASFIPTPVDTSQIVLPPHLDNVRDRLAENIHELWGMNKIELGWSYG KVRDDNKRQHPCLVDFTKLPETESNYNLQMSSETLKTLLALGCHVTQTNINAEEDLKKVK LPKDYVMCNGYKPTPLQLSEVKLTAGQEVLVDKLAENAHNVWAKDRVKQGWTYGIQQDVK SRRNPRLVPYALLDERTKKSNRDSLREAIRTLVGYGYDIDPPDQESCHIVERQSIETIRF FRVEQTYAVKTGKWYFEFEALTGGDMRVGWARPGCRSDFDLGMDDQAYVFDGYKGRRMHM GARFFGQSWNKGDVVGCMINMEDKSMVFTLNGELIITNKGSELCFVDFETEDGFIPVCCL AQSEIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNIPKDHSH IEVTRIDGTVDNPPCLKVTHKTFGTQQSNSDMMYCRLSMPVELHAPHVNPDESQKLSQPP KEDDYGSITTYYHSVRVFAGQDPSSVWVGWVTPDYHYHSKHFSLNKTRTVTVTLGDERGR VHESVRRSNCYMVCAGDVVGSSHSSSRSNIDLEIGCFVDLATGFLSFTANGKELATTYEL ESNSKLFPAVFVRPTSTNLFQFEFVKIKDAMPLSSAIFKSEQRNPVPQCPPRLDVQTIVA VLWSRMPNTFLTVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDILELSEVESLRKF HYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLMSIHLET AKEARLMMNNEFIIPVTDETRSIKLFPDESKRHSLPGVDLSTSLKPRLNFSPLSFITTKK QQHLYSPQIPLGILKEKAISMLTEAVQGGGSHIRDPVGGSVEYQFVPILKLIGTLLIMGV LTSEEVRLILLLIDPNVFGDPEDEEAKVEEVEAAAGGGEKEEVSSNEVKAVEAGEEETKE VKMSVKGLLEKTLPESVKRQMCELLHYFCDCELKQRIEAIVSFSDSFVSKLQYNQKFRYN ELMLALNMSAAVTAKKTKEFRSPPQEQINILLNFAAGEDCPCPEEIQEDLYSFHDELRLH CGIPVEEEEEEEDTSIKGRLLAMLYKIKGPPKKLEEEPTEQEQAAPTNLKELISQTMASW AQECSIQDPELVRVMFSLLRRQYDGIGALLRAMRKSYTISAVSVQDCVNLLASLGQIRSL LSVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAF PKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAASSVMD NNSLALALEEPDLEKVVTYLAGCGLQSCAMLLAKGYPDIGWNPIEGERYLSFLRFAVFSN GESVEENSNTVVKLLIRRPECFGPALRGEGGNGLLAAMLEAIKISEDPVLDLPSTAEGEP TGSGEEEEEEVVHTGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPTS DLVGIISIPLKMPIVNKDGSVTEPDMSASFCPDHKAPMVLFLDRVYGVEEQSFLLHLLEV GFLPDLRASASLDTDVLSTTETALAMNRYIGSALLPLLTRCAGHFSGTEHYAALIDSTLH TIYRLSKGRSLTKAQRDSIEECLLAICKHLRPSMMQQLLRRLVFDVPLLTEYCKMPLRLL TEHYEQSWKYYCLPSGLGSSGMASEEELLLTKKLFWGIFDSLSAKKFDSDLFKTGMACLS ATAGALPPDYVDASPGATLEKQASVDAHGNFDPKPINTANISLPEKLDYIANKFAEHSHV KWSSEKVTAGWKMGESVDDKAKTHPLLKPYKSLSEKERETYRWPVKESLKSMLAMGWNME RTKEGEAMFIEKQSKISESTQDNDNEFILEPPLDLNNITLSRELQGMVEVVAENYHNIWA KKKKTELNSKGGGSHPLLVPYDTLTAKEKYRDREKAQDLFKFLQINGYIITRDLKDMEQD SSSMEKRFAYTFLKRILKYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLID MYFKNHSMYFLSSPSKNLSSSGYASNKEKEMITSLFCKMAALVRHRISLFGSDSAVMVSC LHILAHSLDTRTVMKSGSEMVKAGVRTLFENAAEDLEKTLEMLKLGKFSQSRSQMKGLTQ NITYATTALLPILTALFEHVTMHNFGVYLLVDDVQLSCYRIVTCLYSLGTGKHIFIERHL PALGECLATLVGAMPVAFLEPDLNAHNPLSVFNTKTPRERAILSMPDSVEEMCPEMPRLD RLLKDINDISESGARYTEMPQVIEVILPMLCNYLSYWWEKGTENSAPHTACCTTVCSNHL SIILGNILKILNNNLGIDDAPWMKRIAVYSQPIICKAAADLLRSHFLPTLEKLRKKTVKV VAEEELLKADIKGDTQEAELLVLDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKRPDAQSN ELFTMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGESRTKMSKSGGDQDRKHKKR RGELYSVQTSLIVAALKKMLPIGLNMCTPGDQELISLAKMRYSLKDTDDEVKDHLRENLH LQDKSDDLAVQWQMNLYKDVVVESEERTDPEQTVDRVQSISAAVFHLEQVEQPLRLKKCV FQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFVLGYVRLWIETEEYSFEEKLVQDLAK TPMKIVEEEEEEEVEIKPDPLHQLILHFSHNALTERSFLEEDPLYIAYADMMAKSCAEDE EEEEEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKL GISILNGGNVLVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVT DEGSIGSERGSKVLTNDDFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTLTVNIIISTVD YLLRLQESISDFYWYYSGKDIIDEAGQVNFSKALAVAKQIFNSLTEYIQGPCIGNQQSLA HSRLWDAVVGFLHVFANMQMKLSQDSCQIELLKELMDLQQDMVVMMLSLLEGNVVNGTIG KQMVDTLVESSSNVEMILKFFDMFLKIKDLTTSDNFREYDPENKGVISKKDFQKSMENQK QYTQSEIEFLLSCTEADENDMFNYEEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDPRLA TFLEPAESVLNYFEPYLGRIEIMGGGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDV VNEGGESEKMEMFVNFCEDTIFEMQLASQISEPDVVERQEEEEEEVHNLLEELAEEEENS ELEASSAFTMACISAKKKISNFRQMLTFKILKKQFKKTKKLSLKEMTVGFFSFFWTLFTG FFKGIYSLIFGFFHLIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVLEMEKAE VGDSVSGGTDQAIKPSDKAEQDILMQMINPTPKKGEGLKHVDPGLGDVSETPEPTATVEK KKAVKETKESEPEKADTEKKEKEDKAKEEEPKEEVAQEKPAPKSRNGQSKDAPTSFFASF FAGLEIYQAKMLNTLARNFYNMRFLALFVAFAINFILLFYRVTADEDDSWTSSDDDDEGG EEYFVLEESTGYMAPTLCFLAVFHTALSVLCLIGYYFLKVPLVVFKREKGIARLLEFEGL YITEQPADDDITGQWDRLVINTPSFPNNYWDKFIKRKVINKYGDLYGAERIAELLGLDKS ALDFDPTQETVVEAASLVSWLSSIDTKYHIWKMGVVLTDNSFLYLIWYATMSILGHYNNF FFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSE DEDAPDMKCDDMMTCYLFLLYILLSAICSSSISCSVLSVPPVYPAQCYLFLLYILLSAIC SSSISCSVLSVPPVYPAQCYLLLLYILLSAICSSSISCSVLSVPPVYPAQCYLLLLYILL SAICSSSISCSVLSVPPVYPAQCYLFLLYILLSAICSSCISCSVLSAPPVYPAQCYLILC SSCISCSVLYVPPVYPAQCYLFLQYILLSAI NT seq 14676 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggagaggatgatatccagttcttacgaactgatgatgaggtg gtgcttcaaagtgtcgccaccatccagaaagagaatcgcaagttttgtctgtccgtggag ggactcggtaatcgactatgcttcctggaacctacctctgaggctaagtatgttcctcct gacctgtgtatctgctgtttcatcctggagcagtccctgtctgtccgggccctgcaggag atgttggctcacacggtgcctaacaacgaagggaaagcggaccatgaacagtgggcggcc caggggggtggacaccggaccctgctctatggtcacgccatcctcctacgtcactccttc agtggaatgtacctgacctgcttgaagacgtcgagatcgttgacagacaaactgtcgttt gacgtgggattacaagaacattcaataggtgaggcatgttggtggaccatccatcctgcg tccaagcagaggtcagagggagagaaggtccgtatcggagacgacctaatcctggtcagc gtgtccacagagaggtacctgcacctgtccatctctaacggtagtttccaggtggacgcc tcctttatgcagactctgtggaacgtccagcctacccggtcaggaagtaacgtggctgta ggattcctgtgtggtggtcacgtgatgcgtctgtgtcacggacatgatgagagtctgacc atacctggatcagaggccagcgagatggagcagaggatagtgaactatgaaatgggaaaa ggaacgtccaaggcccgctccctctggaggctggagcccctcaggattggctggagcggc agccacattcgctatgggcaggcgttccgtctgcgtcacctgtctaccggtcactacctg gcgctgaccgaagagcagggtctggtcctacaggagagagagaagtccgataccaagtcc actgctttctgcttcagggctaccaaggaaaagattgagtctggtacgaagaaccgggac attgaaggcatgggagtagcagagatcaagtacggagactcagcctgcttcgtcatgcac gtggctacagggctgtggttgtcctaccagacgcctgatgctaaagcctcccgtatagga cccctcaagagaagggcctgtctgcatgctgagggtcacatggatgacggtctgaccctt cagcgttgtcaacacgaggaggcacgggctgtacgcatcatcaggaacaccacagtcctc ttcagccacttcatcaagggtctggacagtattggaagggataagaacgtggcggtgtct ctgcctaactttgacgaggtgttgcagacgctggatgatctgattgagtatttcaaacag cccgactcagagctggaacatgaggagaaacagactctgctgagatctctcatcaaacga caggacctcttcaaagaggagggcatgctgaccctgctggtgatgtgcatcgaccggctc aacctgtacaacagcgctgctcactttggagagcatgctggggaagaggctggggcggca tggaagagcatcctcaacctcctctaccaactactggcctctctgatcaaagggaacaga aacaactgcacccagttctccaggaacctggactggctggtcagcaagctggagagactg gagtcctcatcaggtatcctggaggttctccactgcatcctgatagagtctcctgaagct ctgaacatcatccagagaggacacatcaagtccatcatctccctgctctacaaacacgga cgcaaccacaagatcctggacgtcctgtgttctctgtgtgtgtgtaacggggtggctgtg agagccaatcagaacctcatctgtgatcacctgcttcccaagagagacctgctcctgcag acacgattggtcaatgatgttcagagtatgaggcccaacatcttcctaggagtggcggag ggttcagcccagtataagaagtggtactttgagctgatgatcgaccaggtggaccactat gtgaccagtgagccatctcacctgcgtgtgggatgggcctccactaagggttacgccccc tacccgggggctggagagggctgggggggcaatggggtgggggatgacctctactcatac agctttgacggactctacctgtggtcaggccgtatcccccgggcagtggcctccatcaac caacacctgttgaacaacgatgacgtggtgagctgttgtctggacctgggcgctccttcc atgtccttcaggatcaacggccagccagtacagggcatgtttgaagacttcaacacagac ggattcttcttccctgtggtcagcttctcagccggggtcaaggtgcgtttcctgttgggt ggtcgtcatggtgactttaagttcctgcccccggcgggttactccccgtgttacgaggcg ctgctccccaaggagaagatgagggtggaggctgtgaaggagtacaagagggatcatgga ggggtcagggacctactggggacaacacagatcctctcccaggcctcattcatccccaca cctgtagacaccagccagattgttctgcctcctcacctggacaacgtgcgggacagactt gcagagaacatccatgaactgtggggcatgaacaagatcgaactgggctggtcctatggc aaggttcgagatgacaacaagaggcagcacccttgcctggtggatttcaccaagctgcct gaaacagagagcaactataacctgcagatgtctagtgaaactctcaagaccctgttggca ctgggatgtcatgtgacacagactaacattaacgccgaggaagatctgaagaaagtcaaa ctgcccaaggactatgtgatgtgtaacggttacaagccaacgccactgcagctgtctgag gtgaaactgacggctggtcaggaggtcctggtagataaactggcggagaacgctcacaac gtgtgggccaaggacagggtcaaacaaggatggacgtacggcatccagcaggatgtgaag agcaggcgtaaccctcgcctggtgccttacgctctgctagacgagagaaccaagaagtct aacagagacagtctgagggaggccatcaggaccctggtgggatacggctatgacatcgac cccccagaccaagagtcctgtcatatcgtggagaggcagagcattgagacgatccggttc ttccgcgtagagcagacgtatgcagtgaagacagggaagtggtactttgagtttgaggcc ctgaccggaggggacatgagggttggctgggctagaccaggctgtaggtcagactttgac ctgggaatggacgaccaggcctacgtcttcgatggatacaagggtcgtcgaatgcacatg ggtgcacgtttcttcggccagtcatggaacaaaggagacgtggtgggttgcatgatcaac atggaggacaagtctatggtcttcaccctcaacggagaactaatcatcactaacaaggga tccgagctctgcttcgtcgacttcgagacagaggatggcttcatcccagtgtgttgtctg gcccagtctgagattggccgtatgaacctggggaaggacgccagcacctttaagtactac accatgtgtggcctgcaggagggcttcgaacccttcgccgtcaacatgaacagagaggtc accatgtggttcagcaaacgcctgcctaccttcgtcaacatccccaaggaccacagccac atcgaggtgacacggatagatgggacagtggacaaccctccgtgcctgaaggtgacacac aagacgtttgggacccagcagagcaacagtgacatgatgtactgcagactgagcatgcct gtagagctccacgctcctcatgtcaatcctgacgagtctcagaaactcagtcagccccca aaagaagatgattatggcagcattacaacatactatcactcagtgagggtgtttgctggc caggacccgtcgtcagtgtgggttggctgggtaacccctgactaccattaccatagcaaa cacttcagcctcaacaagacacgcacggttaccgtaaccctgggagacgagaggggacga gtccacgagagtgttcggaggagtaactgctacatggtgtgtgctggagatgttgtcggc tcctcccactcctcatcccggtctaacatcgacctggagattggctgttttgttgaccta gcaacaggctttctctccttcacagccaatggcaaggagctggccacaacctacgagttg gagtccaacagcaagctgttccctgctgtgtttgtgcgtcccaccagcaccaacctcttc cagtttgagtttgtcaagatcaaggacgccatgcccctgtcgtcagccatctttaagagt gaacaacgtaaccctgtgccccagtgtccaccacgtctggacgttcagaccatcgtagcg gtgctgtggagccgtatgcccaacaccttcctcaccgtggagaccgccagggtctcagag agacacggctgggtggtgcagtgtctggagccactgcagatgatggctgttcatatacct gaggaaaacaggtgtctggacatcctggagctatcggaggtagagagtctgaggaagttc cactaccacaccctgaagctctactgtgccctctgcgcattgggcaacacccgcgtggca cacgccctctgctcccacctcgaccaatcgcagctgctttacaccatcgacaaccaatac ctgtccggcatgctgagagagggcttctataatgtacttatgagcatccacctggagaca gcgaaagaggctcgtctgatgatgaacaacgagtttattatccctgtgaccgatgagacg cgctccatcaagctgttccctgacgagtccaagagacactctctacccggggtagacctc agcacctcgctgaaaccacgtctcaacttctcccctctctccttcatcacaaccaagaaa cagcagcacctctacagcccccagatccccctgggcatcctgaaggagaaggccatcagt atgctgactgaggcagtgcagggaggaggcagtcacatcagagacccagtagggggcagt gtggagtaccagtttgtccccatcctcaagctgattgggaccctgctcatcatgggggta ctcaccagcgaggaggtgaggctgatcctgcttctcatcgatcccaacgtgttcggggat ccagaagatgaggaggcgaaggtggaggaggtggaggcagcagcaggaggaggagagaag gaggaagtgagcagcaacgaggtgaaggccgtggaggctggtgaggaggaaaccaaggag gtcaaaatgtctgtcaagggactgctggagaagacactgcctgagtctgtcaaacgacag atgtgtgagctgctgcattacttctgtgactgtgagttgaagcagcgtatcgaggccatc gtgtccttctcagacagcttcgtgtccaagctgcagtacaaccagaagttcaggtacaat gagttgatgttggccctcaacatgtctgctgctgtcaccgccaagaagaccaaggagttc agatcccctcctcaggagcagatcaacatcctgttgaactttgctgctggggaggactgt ccctgtcctgaagagattcaggaagacctctacagcttccatgatgagctgagactgcac tgtggcatcccggtggaggaggaggaggaggaggaagacacgtctataaagggtcgtctg ctggccatgctctataagatcaagggaccgcccaagaaactagaggaggaacctacagag caggaacaagctgctcccaccaatctgaaggagttgatcagccagaccatggctagctgg gctcaggagtgcagcatccaggacccagagctggttcgtgtgatgttcagcctgctgaga cgtcagtacgacggcatcggagcgctgctcagggccatgaggaagagttacaccatctct gctgtgtcagtacaggactgtgtcaacctcctggcctctctgggccagatcagatcactg ctgtctgtacgcatggggaaagaagaggagaaactcatgatcgacggactgggtgacatc atgaacaacaaggtgttctaccagcaccccaacctgatgagggttctggggatgcacgag actgtcatggaggtgatggtcaacgtgctgggaggagacaagtcacaggagatagcgttt ccaaagatggttgccagttgctgtcggttcctgtgttacttctgtcgtatcagccgacag aaccagaaggccatgttcgaccatctgagttatctactggagaacagttccgtcggactt gcctccccagccatgaggggttccactcccctggacgtagcagcgtcttcagtgatggac aataacagcctggccctcgctctggaggagcctgaccttgagaaggtggtgacctacttg gcaggttgtgggctgcagagctgtgccatgctgctggctaaaggataccctgacattggc tggaaccccatagaaggagagagatatctgtctttcctccgcttcgctgtcttcagcaac ggtgagagtgtggaggagaactctaacacggtggtgaagctgctgatcaggcgtccggag tgttttggtcccgctctgaggggagaggggggcaacggcctgctggcggccatgttggaa gccattaagatatcagaggaccctgttctggacctgccctctacagctgaaggagaacct actgggtctggtgaggaggaagaggaagaagtggtccatactgggaacgccatcatgtcc ttctactctgcactcattgacctgctgggacgctgcgctcctgagatgcatctgatcaac aagggtaaaggtgaggccttgcgtatccgtgccatcctgcgctccctggttcctacttca gacctggttggcatcatcagtattccactcaagatgcccatcgtcaataaagatggtagt gtgacagagccagacatgtcggctagtttctgtccggaccacaaggccccaatggtgttg ttcctggatcgtgtgtacggcgtggaggaacagagcttcctgctacacctgttggaagtg ggcttcctgcctgacctccgtgcctccgcttccctggacacggatgtgctaagcaccaca gagacagctctggccatgaacaggtacatcggttcggccctgcttcccctgctgaccagg tgtgctggccacttctcgggcacggagcactacgcggcgctcatcgactctaccctccac actatctatcggctgtccaagggccgctccctcaccaaggcccagagagactctatcgag gagtgtctgcttgccatctgcaaacacctgcgcccttccatgatgcaacagctgctgaga cgtctggtgttcgatgttcccctgctgacagagtactgcaagatgcccctcaggctgttg actgaacactatgagcagagctggaagtactactgtcttccctcgggtctggggagctcc ggcatggcctcagaggaagaactgttgctcaccaagaaactcttctggggaatattcgac tccctctcagcgaagaagtttgactctgacctgttcaagactggcatggcctgtctgagt gctaccgctggggcgttgccacctgactatgtggatgccagccctggtgccaccttggag aagcaggcgtctgtggatgcacacggcaacttcgaccccaaacccatcaacactgccaat atctcccttccagagaaactggactacattgccaacaagtttgcagagcattcccacgtc aagtggtcctcagagaaggtgacagcgggttggaaaatgggagagagtgtggatgacaag gctaaaactcacccactgttgaagccgtataaatccctcagtgagaaggagagggaaaca taccgttggccagtgaaggagtctttaaagagcatgctggcaatgggttggaacatggag aggaccaaagagggggaggccatgttcatcgagaaacaaagcaagatctccgagtccact caggacaacgataatgaattcatcctggaaccacccttggacctgaacaatattactcta tccagagagttgcaggggatggtggaggttgtagcagagaactaccacaacatctgggcc aagaagaagaagactgagctgaacagtaaaggaggagggagccacccgttgctggtgccc tatgacaccctgacagccaaggagaagtacagagacagggagaaggcccaggatctcttt aagttcctgcagatcaatggatatatcatcaccagagacctgaaagacatggagcaggac tcgtcgtccatggagaagaggtttgcctacacgttcctcaagaggattctgaagtatgtg gactcagctcaggagttcattgctcacctggaggccatggccaccagtggaaagacagac aaatcaccccacgatcaggaaataaaattctttgctaaggtgctgctacctctcatagac atgtactttaagaaccacagcatgtacttcctgtcctcgcccagtaagaacctgagcagc agtggctacgcctctaacaaagagaaggagatgatcactagcctgttctgtaagatggca gctcttgtcagacacaggatttccctctttgggagcgactcggctgttatggtgagctgt ctacacatcctggctcattccctggacacaaggacagtgatgaagtcaggctcagaaatg gtgaaggctggggtcaggacgttatttgagaacgcagcggaggacctagagaagaccctg gaaatgctgaagctggggaagttcagccagtcccggagccagatgaagggcttgacccag aacatcacctacgccaccaccgctctgctgcccatcctcacagctctgttcgaacatgtc accatgcataactttggagtctacctgctggtggatgatgtccagctgtcgtgctatcgc atcgtgacctgtctctactcactgggcacggggaaacacatcttcatagagaggcaccta ccagccctaggggagtgtctggccaccctggtaggagccatgcctgtagctttcctggag cctgatcttaacgctcacaaccccctgtctgtcttcaacaccaagacaccgcgagagagg gccatcttgagtatgcctgactctgtggaggagatgtgtccagagatgcctcgtctggat cgcctgctgaaggacatcaacgacatctcagagtctggagctcgctacacagagatgcca caggtgattgaggtgatcctgcccatgttgtgtaactacctgtcctactggtgggagaaa ggaacagagaactctgctccacacacagcctgctgcaccaccgtgtgctccaaccacctc agcatcatcctggggaacatcctgaagatcctcaacaacaacctgggcatcgacgacgct ccctggatgaagcggatcgcagtctactctcagccaatcatctgcaaggctgctgcggac ctactgaggagtcacttcctgcccactctagagaaactcaggaagaagacagtgaaggtg gtggcagaggaggaactgctgaaggctgacattaaaggagacactcaggaagctgagctt ctcgtcctggatgagtttgctgtcctctgtagagacctgtacgccttctacccaatgctc atccgctatgtggacaacaacagatccagatggttgaagaggcctgatgctcagtccaac gagctcttcaccatggtggctgagatcttcatcctctggtgcaaatcacacaacttcaaa agggaagagcagaactttgtggttcagaatgaaatcaacaacctgtctttcctgactgga gaaagtagaaccaagatgtccaagtcaggtggtgaccaggataggaagcacaagaagcgg cgtggagagttatactctgtccagacctctctgatcgtagccgcactgaagaagatgctg cccatcggactcaacatgtgcaccccaggagaccaggagctcatctcattagccaagatg cgatacagtctgaaagacaccgacgatgaggtgaaggatcacttgcgtgagaaccttcat cttcaggacaagtctgatgacctggctgtgcagtggcagatgaacctgtataaggatgtg gtggtggagagtgaggaacgtacagacccagaacaaactgtggacagagtacagagcatc tctgctgcagtcttccacctggagcaggtggagcagcctctgaggttgaagaagtgtgtg tttcagaagctactgtccaaacagcgtaaacgcgccgtggtggcctgcttccgtatggct cctctttacaacctccccaggcatcgttctattaacctcttcgtgttgggctatgtgaga ctatggatagagacagaggagtactcctttgaggagaagctagtgcaggacctggcaaaa accccgatgaagatcgtggaggaggaggaagaggaggaggttgagattaagccagaccct cttcatcagcttatccttcacttcagccacaatgccctgacagagagaagtttcttggaa gaagatccgctgtatattgcatatgcagacatgatggcaaagagttgtgcagaggatgaa gaggaggaagaggaggaagaggggaaagagaagacatttgaggaaaaggaaatggagaag cagaagatcttgtaccagcaggccagactacacgcccgcggggctgctgagatggtgcta cagatgatcagcgccagtaaaggtcgactaggtcctatggtgacctgtaccctcaaactg ggcatctccatcctcaacggaggcaacgtgctggtccagcagaaaatgctggattacctg aaagagaaaagagacgcaggctttttcaagagtttgtcaggcctcatgcagtcctgcagt gtcctggacttgaatgcctttgagagacagaacaaagcggaaggtctggggatggtgaca gatgaaggctccatcggcagtgagcggggttccaaagttctgacgaatgatgacttcacc aaagatctcttccggtttttgcaactgctctgtgaggggcacaatggggatttccaaaac ttcctgagaacacaaacaggaaacacgttgactgtcaacattatcatcagcacagtggac tacctgctgcgccttcaggaatctatcagtgacttctactggtattattctgggaaagac attatcgacgaggcagggcaggtcaacttctccaaagccttagctgtcgcgaagcagatc ttcaactcactcactgagtacatccaggggccatgtattgggaaccagcagagtctggcc cacagcagactgtgggatgcagtggtgggattcctgcatgtgtttgccaacatgcagatg aagctgtcccaggactcgtgtcagattgagctgctcaaggagttgatggatcttcagcaa gacatggtggtgatgatgctgtcactgctcgagggcaacgtggtgaatggaacgattgga aagcagatggtagacactctggtggagtcctccagcaacgtcgagatgatcctcaagttc ttcgacatgttcctcaagatcaaggacctgaccacctctgacaacttcagagagtacgac cccgagaacaagggggtcatctccaaaaaagatttccagaagtccatggagaaccagaag cagtacacccagtcggagattgagttcctcctctcctgcaccgaggccgacgaaaacgac atgttcaactacgaggagtttgtggagcggttccacgagccggccaaagacatcggcttc aacgtagccgtgctgctcaccaacctctctgagcacatgcctcacgatccccgtttggcc acattcctggaaccagctgagagcgtgctgaactacttcgaaccgtacctgggccgcatc gagatcatgggcggagggaagcgcatcgagagggtctattttgagatcagcgagtccagt cgtacacaatgggagaagccacaggtcaaagagtccaagagacagttcatctttgatgtg gtcaacgaggggggagaaagcgagaagatggagatgtttgtgaacttctgcgaagacacc atctttgagatgcagctggcatctcagatctcggagcccgacgtggtggagcgccaggaa gaggaagaggaggaggtgcacaacttgttagaagagcttgcagaggaagaggagaatagc gagctggaagcttcctcggctttcaccatggcctgcatctccgccaagaagaagatctcc aacttcagacagatgctgaccttcaagatcctcaagaagcagttcaagaagaccaagaag ctgagcttgaaggagatgaccgttgggttcttctccttcttctggacgctcttcacaggg ttcttcaaggggatctacagtctcatcttcggattcttccacctcatctggtcgtccatg ttcggaggcgggctcgtcgaaggagccaagaacatgaaggtgacagacatcttgggtaac atgcccgaccccacccagtttggtatccacggcgatgtgttggagatggagaaggccgag gttggtgattctgtgtcgggcgggacagaccaggccatcaaaccgtcagacaaggcagag caggacatcttaatgcagatgattaatcccacaccaaagaaaggggaagggttaaaacac gttgatcctggactgggagacgtctctgagactcctgagcccaccgccactgtggagaag aagaaggctgttaaagaaactaaagagtcggaaccagagaaagcagacacagagaagaag gagaaggaagacaaggccaaggaggaggagcctaaagaggaagtggctcaagagaagccc gcccccaagtccagaaacggccaatcaaaggatgctcctacttccttctttgccagcttc tttgctgggctggagatctaccaggccaagatgctgaacacgttggctcggaacttctac aacatgcgtttcctggctctgtttgtggcgtttgccatcaacttcattctactgttctac agggtgactgctgatgaggatgactcctggactagttctgatgatgatgatgaaggtggt gaggagtactttgtcctggaggagagtacaggctacatggctcctacactgtgtttcctt gctgtgttccacaccgccctctctgtcctctgtttgattggctactactttctcaaggtg cctctggtggtgtttaagcgagagaaagggatcgccaggctcttggagtttgaaggtctc tacatcacagagcagccggcagacgatgacatcacaggacagtgggaccgcctcgtcatc aacacaccgtccttccccaataattactgggacaagtttatcaaacgaaaggtcattaat aagtatggagacctgtacggagctgagcggatagctgagctgttgggtctggataagagc gccctggacttcgaccctactcaggagaccgtggtggaggcggcttctcttgtatcctgg ttgagctctatcgacaccaagtaccacatctggaaaatgggagtggtgctgactgacaac tcgttcctgtacctgatctggtacgccaccatgtccatcctggggcactataacaacttc ttcttcgctgcccatctgctggacatcgccatgggcttcaagaccctccggaccatcctg tcttccgtcactcacaacggaaaacagttggtgctgaccgtaggtctgttggcggtggtg gtgtatctgtatactgtggtggccttcaacttcttcaggaagttctacaacaagagcgag gacgaggacgcacctgatatgaagtgtgacgacatgatgacttgctatctgttcctcctg tatatcctgctcagtgctatctgttcctccagtatatcctgctcagtgctatctgttcct cctgtatatcctgctcagtgctatctgttcctcctgtatatcctgctcagtgctatctgt tcctccagtatatcctgctcagtgctatctgttcctcctgtatatcctgctcagtgctat ctgctcctcctgtatatcctgctcagtgctatctgttcctccagtatatcctgctcagtg ctatctgttcctcctgtatatcctgctcagtgctatctgctcctcctgtatatcctgctc agtgctatctgttcctccagtatatcctgctcagtgctatctgttcctcctgtatatcct gctcagtgctatctgttcctcctgtatatcctgctcagtgctatctgctcctcctgtata tcctgctcagtgctatctgctcctcctgtatatcctgctcagtgctatctgatcctctgt tcctcctgtatatcctgctcagtgctatatgttcctcctgtatatcctgctcagtgctat ctgttcctccagtatatcctgctcagtgctatctga

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