Orcinus orca (killer whale): 101270317
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Entry
101270317 CDS
T05247
Symbol
PDE3B
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform X1
KO
K13296
cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:
3.1.4.17
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00230
Purine metabolism
oor01100
Metabolic pathways
oor04022
cGMP-PKG signaling pathway
oor04024
cAMP signaling pathway
oor04371
Apelin signaling pathway
oor04910
Insulin signaling pathway
oor04914
Progesterone-mediated oocyte maturation
oor04922
Glucagon signaling pathway
oor04923
Regulation of lipolysis in adipocytes
oor04924
Renin secretion
oor05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101270317 (PDE3B)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
101270317 (PDE3B)
04024 cAMP signaling pathway
101270317 (PDE3B)
04022 cGMP-PKG signaling pathway
101270317 (PDE3B)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101270317 (PDE3B)
04922 Glucagon signaling pathway
101270317 (PDE3B)
04923 Regulation of lipolysis in adipocytes
101270317 (PDE3B)
04914 Progesterone-mediated oocyte maturation
101270317 (PDE3B)
04924 Renin secretion
101270317 (PDE3B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
101270317 (PDE3B)
Enzymes [BR:
oor01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
101270317 (PDE3B)
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GFIT
Motif
Pfam:
PDEase_I
DUF1129
Motif
Other DBs
NCBI-GeneID:
101270317
NCBI-ProteinID:
XP_012391975
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Position
8:complement(41085046..41263708)
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AA seq
1120 aa
AA seq
DB search
MRRDERDAKAMRYPQPPDGAGSPLESLRNGYVKGCVSPLRQDPPRGFFFHLCRFCNVELL
LPPLPASPQQPRRGSPFSRARLSLGALAAFVLALLLGSGPESWAVGAARLRTLLSVCSHS
LSPLFSIACAFFFLTCFLTRTKRDPGPGRSGGGSWWLLALPACCYLGDFLVGQWGSWSWG
DGDAGARAPHTTPAVAGRLFLVLSCVGLLTLAQPGRLRHSILVLLFSGFVWWVSFTSLGA
LPPALRPLLSCLVGGVGCLLALGLDHFFQIREAPHHPRLSSTAEEKVPVIRPRRRSSCVS
FGETSASYYGSCRMFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGSGVDLSVLNEA
RNMVSDLLVDPTLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYHCSEIEDPADK
GDRKLHKGLNSRNSLSTPQLRRSSGTSGLPPIDQTSPRWERNNGKRSHQEFGVLSQGCYL
NGPFSSNPLTIPKQRSSSVSLTHHIGLRRAGTLPGLNSPSHGPMSAGSPTNRSPIEFPDT
ADFLTKPSVILHRSLSNAPNSPDFYQQLRNSDSNLCNSCGHQILKYASASEPEAGTDCHR
EKSGDEDNTVFSKASFNLTEAQQEVETENRDCRKLLWEGDNHLKEEAQNEEQPNIEQEAS
RDLILIEDYDSLIENMGNWNFQIFELVENMGEKSGRILSQVMYTLFQDTGLLEIFKIPTL
QFMNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPIPGLQQIHNDHGAGNETDSNGR
INPGRIAYISSRSCCIPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNA
PQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLNLDNVQFKRFRFLVIEAILATDLKKH
FDFLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPTKVRDLHLKWTEGIVNE
FYEQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWIEAEE
DDDTESCYDEEDGEELDTEDEEIEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIE
EEEKYKADGNKLQVENSSLPQGDEIQVIEEADEEEERQLE
NT seq
3363 nt
NT seq
+upstream
nt +downstream
nt
atgaggagggacgagcgagacgccaaagccatgcggtacccgcagccgccggacggggcc
ggctcgcccctcgagagtctgaggaacggctacgtgaagggctgtgtgagccccctgcgg
caggaccccccgcgcggcttcttcttccacctctgccgcttctgcaacgtggagctgttg
ctgccgccgctgccggcctccccccagcagccgcggcgcggctctcccttctcccgggcg
cgcctctcgctgggcgccctggccgcctttgtcctcgccctgctgctcggctcgggaccc
gagagctgggctgtcggggccgcccggctgcggaccctgctgagcgtctgttcgcacagc
ctcagccccctcttcagcatcgcctgtgccttcttcttcctcacctgcttcctgacccgg
accaagcgggaccccgggccgggccggagcggtggcggctcctggtggctgctggcgctg
cccgcctgctgttacctgggggacttcttggtggggcagtgggggtcttggtcttggggg
gacggagacgctggggcccgggccccgcacacgaccccggcggtggccggtaggctgttc
ttggtgctgagctgcgtgggattgctgacgctcgcgcagccggggaggctccggcacagc
atcctggtgctgctcttctccggcttcgtctggtgggtgtccttcaccagcctcggggcg
ctgcctccagccctccggccgctgctgtcctgcctggtggggggcgtcggctgcctgctg
gccctggggctggatcacttcttccaaatcagggaagctccccatcatcctcggttgtcc
agtaccgcggaggaaaaagtgcctgtgatcagaccccggaggaggtccagctgcgtgtcg
ttcggagaaacttcagccagttactatggcagttgcagaatgttcaggagaccttcattg
ccttgcatttcgagagaacagatgattctttgggattgggacttaaagcagtggtataaa
cctcactatcagaattctggaggtggaagtggagttgatctttcggtgctaaatgaggct
cgtaatatggtgtcagatcttctggttgacccaacccttcccccacaagtcatttcttcc
ctccggagtatcagtagcttgatgggtgctttctctggctcctgtaggccaaagattaat
cctctcacaccatttcctggattttatcactgctctgaaatagaggacccagccgacaaa
ggagatagaaaacttcacaaggggctaaacagtaggaatagtttatcaaccccacagctg
agaaggagctcgggaacctcaggtctgccacctattgaccagacttctccaaggtgggaa
cgcaataatggcaaaaggtctcaccaagaatttggcgttttaagtcaaggatgctatcta
aatggaccttttagttcaaatccactgacaatcccgaagcaaaggtcatcttctgtatcg
ttaacccaccatataggtctaagaagagctggtactttacccggcctgaattctcccagt
catggaccaatgtctgctggctctccaactaaccgatcgcctatagaatttcctgacact
gctgattttcttactaagccaagtgttattttacacagatctctgagcaatgcacccaat
tcaccagatttttatcagcaacttagaaattctgatagcaatttatgtaacagctgtgga
catcaaatattgaaatatgcttcagcatctgaaccagaggctggtacagactgccacagg
gaaaagtcaggtgatgaagacaataccgttttctcaaaagcatcattcaaccttacggaa
gctcaacaagaagtggaaacagagaacagagactgcagaaaattactttgggaaggtgat
aatcacctaaaagaagaggcacagaatgaagagcaaccaaatattgaacaagaagcatca
cgggacctgattttaatagaagattatgactcattaatagaaaatatgggtaactggaat
tttcaaatttttgaacttgtagaaaacatgggagagaaatcaggaaggatcctcagtcag
gttatgtataccctatttcaagacactggcttattggagatatttaaaattcctactcta
caattcatgaactactttcgtgcattagaaaatggttatcgagacattccttatcacaat
cgtatacatgccacagatgtcctacatgctgtttggtatctgacaacacggccaattcct
ggtttacagcagatccacaatgatcatggagcgggaaatgaaacagattctaacggtaga
attaaccctgggcgaattgcttacatttcttcgaggagttgctgtattccagatgagagc
tatggctgcctgtcttcaaacattcctgcactggaattgatggctctgtacgtggcagct
gccatgcatgattacgaccacccagggcggacaaatgcatttctagtggctacaaatgcc
cctcaggcagttttgtacaacgacagatctgttctggaaaatcatcacgctgcatcagcc
tggaatctgtatctttctcgtccagagtacaacttccttcttaatcttgataatgtgcaa
ttcaagcgctttcgttttttagtcattgaagcaatccttgccacagatcttaaaaagcat
tttgatttccttgctgaattcaatgccaaggccaatgatgtaaacagtaatggtatagaa
tggagtaatgaaaatgatcgcctgttagtatgccaggtgtgcatcaaactggcagacata
aatggcccaacaaaagttcgagacttgcatttgaaatggacagaaggcattgtcaatgaa
ttttatgagcagggagatgaagaagcaaatcttggtttgcccatcagtcccttcatggat
cgttcttctcctcaactagcaaaactccaggaatcttttatcactcacatagtgggtccc
ctgtgtaactcctatgacgctgctggtttgctaccgggtcagtggatagaagcagaagag
gatgatgatactgaaagttgttatgatgaagaagatggtgaagaattagatacagaggat
gaagaaatagaagacaacctaaatcctaaaccacaaagaaggaaaggcagacggcgaata
ttttgtcagctaatgcaccatctcaccgaaaaccacaagatatggaaggaaatcatagag
gaagaagagaaatataaagctgatgggaataaactacaggtggagaattcttccttacct
caaggagatgagattcaggtcattgaagaagcagatgaagaggaagagagacagttggaa
taa
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