KEGG   Orcinus orca (killer whale): 101286888
Entry
101286888         CDS       T05247                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X7
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04010  MAPK signaling pathway
oor04020  Calcium signaling pathway
oor04022  cGMP-PKG signaling pathway
oor04114  Oocyte meiosis
oor04218  Cellular senescence
oor04310  Wnt signaling pathway
oor04360  Axon guidance
oor04370  VEGF signaling pathway
oor04380  Osteoclast differentiation
oor04625  C-type lectin receptor signaling pathway
oor04650  Natural killer cell mediated cytotoxicity
oor04658  Th1 and Th2 cell differentiation
oor04659  Th17 cell differentiation
oor04660  T cell receptor signaling pathway
oor04662  B cell receptor signaling pathway
oor04720  Long-term potentiation
oor04724  Glutamatergic synapse
oor04728  Dopaminergic synapse
oor04921  Oxytocin signaling pathway
oor04922  Glucagon signaling pathway
oor04924  Renin secretion
oor05010  Alzheimer disease
oor05014  Amyotrophic lateral sclerosis
oor05020  Prion disease
oor05022  Pathways of neurodegeneration - multiple diseases
oor05031  Amphetamine addiction
oor05152  Tuberculosis
oor05163  Human cytomegalovirus infection
oor05166  Human T-cell leukemia virus 1 infection
oor05167  Kaposi sarcoma-associated herpesvirus infection
oor05170  Human immunodeficiency virus 1 infection
oor05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oor05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101286888 (PPP3CB)
   04310 Wnt signaling pathway
    101286888 (PPP3CB)
   04370 VEGF signaling pathway
    101286888 (PPP3CB)
   04020 Calcium signaling pathway
    101286888 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    101286888 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101286888 (PPP3CB)
   04218 Cellular senescence
    101286888 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101286888 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    101286888 (PPP3CB)
   04660 T cell receptor signaling pathway
    101286888 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    101286888 (PPP3CB)
   04659 Th17 cell differentiation
    101286888 (PPP3CB)
   04662 B cell receptor signaling pathway
    101286888 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    101286888 (PPP3CB)
   04921 Oxytocin signaling pathway
    101286888 (PPP3CB)
   04924 Renin secretion
    101286888 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    101286888 (PPP3CB)
   04728 Dopaminergic synapse
    101286888 (PPP3CB)
   04720 Long-term potentiation
    101286888 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    101286888 (PPP3CB)
   04380 Osteoclast differentiation
    101286888 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101286888 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101286888 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    101286888 (PPP3CB)
   05163 Human cytomegalovirus infection
    101286888 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101286888 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    101286888 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101286888 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    101286888 (PPP3CB)
   05020 Prion disease
    101286888 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    101286888 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    101286888 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101286888 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:oor01009]
    101286888 (PPP3CB)
Enzymes [BR:oor01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     101286888 (PPP3CB)
Protein phosphatases and associated proteins [BR:oor01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     101286888 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 101286888
NCBI-ProteinID: XP_012389656
LinkDB
Position
14:complement(31400049..31449953)
AA seq 525 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSF
EEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHGAQ
NT seq 1578 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgagtcgtcaaagctgtccctttccccccaacgcatcgcttgacatct
gaagaagtttttgatatggatgggatacccagggttgatgttttgaagaaccacttagta
aaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggtgctgccatt
cttcggagagagaaaaccatgatagaagtagaggctccaattacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggtcctgaagattctatacccaagcacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagcctgcctcttgctgcactttta
aaccaacaatttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgcta
tggtctgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacaatttaactgttctccacatccttactggttgcccaattttatggatgtcttcaca
tggtctttaccatttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaacttatgactgaaggagaagaccagtttgatgtaggttcagctgca
gcccggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagggtcttc
tctgttctcagggaggagagtgaaagtgtgctgacactcaagggcctgactcccacaggg
atgttgcctagtggagtgttagctggaggacggcagaccctgcaaagtgccacagttgag
gctattgaggctgaaaaagcaatacgaggattctctccaccacatagaatctgcagtttt
gaagaggcaaagggtttggataggatcaatgagagaatgccaccccggaaagatgctgta
cagcaagatggtttcaattctctgaacaccgcacatgccactgagaaccacgggactggc
aaccatggtgcccagtga

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