KEGG   Ochotona princeps (American pika): 101536661
Entry
101536661         CDS       T07609                                 
Symbol
CAD
Name
(RefSeq) CAD protein isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
opi  Ochotona princeps (American pika)
Pathway
opi00220  Arginine biosynthesis
opi00240  Pyrimidine metabolism
opi00250  Alanine, aspartate and glutamate metabolism
opi01100  Metabolic pathways
opi01240  Biosynthesis of cofactors
Module
opi_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:opi00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    101536661 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    101536661 (CAD)
   00220 Arginine biosynthesis
    101536661 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:opi01002]
    101536661 (CAD)
Enzymes [BR:opi01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     101536661 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     101536661 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     101536661 (CAD)
Peptidases and inhibitors [BR:opi01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   101536661 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   101536661 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp Dala_Dala_lig_C MGS ATPgrasp_Ter Amidohydro_1 DHOase ATP-grasp_3 GARS_A Peptidase_C26
Other DBs
NCBI-GeneID: 101536661
NCBI-ProteinID: XP_004582728
LinkDB
Position
2:20551658..20572815
AA seq 2225 aa
MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPQDEVDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSAACTLHEWLQQHGIPGLQGVD
TRELTKKLREQGSLLGKLVQDGTEPATLPFLDPNARPLVPEVSIKTPQVFNAGGSPRILA
LDCGLKYNQIRCLCRRGAEVTVVPWDTAVDRQEYDGLFLSNGPGDPASYPSVVSTLGRVL
SEPNPRPVFGICLGHQLLALAVGAKTYKMRYGNRGHNQPCLLVDSGRCFLTSQNHGFAVE
TDSLPAGWAPLFTNANDRSNEGIVHESLPFFSVQFHPEHKAGPSDMELLFDVFLETVKES
VAGKPGGQTVRERLAECLCPPGTPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAASSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASNKEELSALVAPAFAHTSQVLVDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQALG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIALPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVERLYQLTRIDRWFLHRM
KRIITHAQLLEQHRGQPLPPDLLHQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGSSHDLTFQTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESAHQFCQS
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGLVVAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIQAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEKVEPVGLMAGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVACFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LEQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMV
CAMPNTRPPITDAPALALAQKLAEAGARCDYTLFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPAHLPIVAHAERQSVAAVLMVAQLTQRPVHICHVARKEE
ILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVI
DCFASDHAPHTLEEKKGPSPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
HLPPQEDTYVEVDLEHEWTVPSHMPFSKARWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGVVPQLQPSAPASNEITTTPERPRRGVPGLPDSRFHLPPRIHRASD
PGLPAEEPKEKSSRKATEPELMGTPDGSCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHS
LVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGSVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLRMPPNVWDFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYES
CFGQFIITPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq 6678 nt   +upstreamnt  +downstreamnt
atggcggccctggtgttggaagatgggtcggtcctgcggggccagccctttggggcagct
gtgtcgactgccggggaagtggtgtttcagactggcatggtcggctatcccgaggccctc
accgacccctcctataaagctcagatcttggtgctgacataccccctgatcggcaactat
ggcatccctcaggacgaggtggatgagttcggcctcagcaagtggtttgagtcctccggg
atccacgtagcaggactggtggtgggagagtgctgccccacgcccagccactggagtgct
gcctgcaccctgcatgagtggcttcagcaacacggcattccaggcttgcaaggagtggac
actcgggagctgaccaagaagttacgagaacaagggtctctgctggggaagctggtgcag
gatgggacggagcctgcaaccctgccgtttttggaccccaatgcccgccccctggtccca
gaggtgtccatcaagaccccgcaggtattcaatgctggaggaagccctcggattctagct
ttggactgtggtctcaagtataatcagatccgctgcctctgccggcgtggggctgaggtc
accgtggtgccctgggacacggcagtggacagacaggagtacgacggtctcttcctaagt
aatggcccaggcgacccagcctcctaccccagcgtggtgtctacactgggccgtgtgtta
tctgaaccaaacccacgacctgtcttcgggatctgcctgggacaccagctcctggccctt
gccgttggggccaagacttacaagatgaggtatggaaaccgagggcataaccagccctgc
ttgctggtggactctgggcgctgcttcctgacctcccagaaccatggctttgccgtggag
acagactcgctgccagcaggctgggcacccctcttcaccaacgccaacgatcggtccaac
gaaggcattgtgcacgagagccttcccttcttcagcgtccagtttcacccagagcacaag
gctggcccttctgacatggagctactcttcgatgtcttcctggaaactgtgaaagagtcc
gtagctgggaagcctgggggccaaacagtccgtgagcggctggctgagtgcctctgtccc
cctgggacgcccatcccaggctctggccttccgcctccacgtaaggtgctaatcctgggc
tcagggggcctctccattggccaggcaggagagtttgactactcgggctcccaggcgatt
aaggccctgaaagaggagaacatccagaccttgctgatcaaccccaacatcgccacggtg
cagacctcacaggggctggccgacaaggtctacttccttcccattacacctcactatgtc
acgcaggtgatccggaatgagcggccagatggcgtgttattgacctttggtggccagaca
gctctgaactgcggtgtggagctgaccaaggctggggtgctggctcggtatggagtccgg
gtcctgggcacacctgtggagaccattgagctaaccgaggaccgccgggcctttgcagcc
agaatggcggagattggggagcatgtggcccccagtgaggcggcaagctccctggaacag
gcccaggcagctgctgagcggctggggtaccctgtactggttcgggcagcctttgccctg
ggcggcctgggctctggctttgcttccaataaggaggagctctctgctcttgtggccccg
gcttttgcccacactagccaagtgctagtggacaaatccctgaagggatggaaggagatc
gagtatgaagtagtgagagacgcctatggcaactgtgtcacggtatgtaacatggagaac
ttagacccactgggcatccacactggtgagtccatcgtggtggccccgagccagaccctg
aatgacagggagtaccagctgctgcggcagacggcaatcaaggtgacccaagccctgggc
atcgttggggaatgcaacgtgcagtatgccttgaacccagagtctgagcagtattatatc
atcgaagtgaatgccagactgtctcgcagctctgccctggccagtaaggccacaggctac
ccgttggcctacgtcgcagccaagctggccttaggcattgccctgcctgagctcaggaac
tccgtgacagggggcacggcagcctttgagcccagcctggattactgtgtggtcaagatt
ccccgctgggacctaagcaagttcctgcgtgtgagcaccaagattgggagctgcatgaag
agtgtgggtgaagtcatgggcattggacgttcgtttgaggaggccttccagaaagccctg
cgcatggtggatgagaactgcgtgggctttgatcacaccgtaaagccggtcagcgatatg
gagctggagacgccgactgacaagcggatctttgtggtggcagccgccctatgggctggc
tactcagtagagcgcctctaccagctcacccgcatcgaccgctggttcctgcaccggatg
aagcgcatcataacgcacgcccagctgctggagcagcaccgcgggcaacctctgcctcca
gacctgctgcatcaggccaagtgcctcggcttctcagacaagcagattgccctggcagtt
ctgagcacagagctggctgtgcgcaagctgcgccaggagctgggaatctgcccagcagtg
aagcagatcgatacagttgcagctgagtggccagcacagacaaactacctgtacctgacc
tactggggcagtagccatgacctcaccttccagacgcctcatgttctggtcctcggctcc
ggcgtctaccgcatcggctccagtgttgagtttgactggtgtgccgtaggctgtatccag
cagctgcggaagatggggtacaagaccatcatggtgaactacaacccagagaccgtcagc
accgactatgacatgtgcgaccgactctacttcgatgagatctccttcgaggtggtgatg
gacatctatgaactggaaaaccctgaaggtgtgatcctgtccatgggtgggcagctgccc
aacaacatggccatggctttgcaccggcagcagtgccgggtgctgggcacctcccctgaa
gccatcgattctgctgagaaccggttcaagttctcccggctcctggataccatcggtatc
agccagccccagtggcgggaactcagtgacctcgagtctgctcaccagttctgtcagtct
gtggggtacccctgcgtagtccgcccctcctatgtcctgagtggtgctgccatgaatgtg
gcctacaccgatggggacctggagcgcttcctgagcagtgcggcagctgtctccaaggag
caccccgtggtcatctccaagttcattcaggaggctaaggagatcgacgtggatgctgtg
gcctgtgacgggttggtggttgccattgccatttctgagcacgtggagaatgcaggtgtg
cactccggcgatgccacactggtgacacccccacaggacatcacacccaaaactcttgag
cggatccaggccattgtacatgctgtggggcaggagctgcaggtcacaggccccttcaac
ctgcagctcattgccaaggacgaccaactgaaggtcattgagtgcaacgtgcgcgtctcc
cgctccttccccttcgtctctaagacactgggtgtggatctggtggccttggccacgcgg
gtcatcatgggagaaaaggtggagcctgtggggctcatggctggctccggagtcgtgggg
gtaaaggtacctcagttctccttctctcgtttggcgggtgcagacgtagtattgggtgta
gaaatgaccagtaccggggaggtcgcctgcttcggtgagagccgttgtgaagcctacctc
aaggccatgctaagcactggcttcaagatcccaaagaagaacatcttgctcaccatcggg
agctacaagaacaaaagcgagctgctgccaactgtgcggctgctggaaagtctgggctac
agcctctatgccagcctgggcactgctgacttctacacagagcacggtgtcaaggtaaca
gctgtggactggcacttcgaggaggctgtggacggggagtgccccccacagcgaagcatc
ctggagcagctggctgagaaccactttgagctggtaatcaacctgtccatgcgcggggct
ggtggccggcgcctctcttccttcgtcaccaagggttaccgcacccggcgcctggctgcc
gacttctccgtgcccctcatcatcgacatcaaatgtaccaagctcttcgtagaggctctg
ggccagatcgggcctgcccctcctctgaaggtgcatgtggactgtatgacctcccagaaa
cttgtgcgcctacccgggctgatcgacgtccatgtgcacctgcgtgagccaggggggaca
cacaaggaggactttgcctctggcacagcagctgccctggccgggggcatcaccatggtg
tgcgccatgccaaatacccgtccccccatcactgatgcccctgccttggcgctggcccag
aagctggccgaggctggcgcccgctgtgactacacacttttccttggagcctcgtctgaa
aacgcagggactctgggtgccgtggccgggtcggccgcagggctgaagctctaccttaac
gagactttctctgagctgcggctggacagtgtggcacagtggatggagcactttgagaca
tggcctgcccacctccccattgtggcccatgctgagcggcagagtgtcgctgctgtcctc
atggtggctcagctgacccagcgccccgtacacatctgtcacgtggcgcgcaaggaggag
atcctgctcatcaaagctgcaaaggcacgagggctgccagtgacctgtgaggtggcacct
caccacttattcttgagccacgatgacctggaacgcctggggcctgggaagggcgaggtc
cggcctgagcttggctcccgccaagatgtggaggcgctctgggagaacatggccgtcatt
gactgctttgcctctgaccacgccccccacaccctggaggagaagaaagggcccagccct
ccacctggcttcccagggctagagaccatgctgccgctgctgctgacagccgtaagcgag
ggccggctcagcctggatgacctgctgcagcggctgcaccacaaccctcggaggatcttt
cacctgcctccccaggaggacacctacgtggaggtggatctggagcatgagtggacagtg
cccagccacatgcccttctccaaagcccgctggactccctttgaagggcagaaggtgaaa
ggcaccgtgcgccgggtggtcctgcgaggggaagtggcctacattgatgggcaggtgctg
gtgcctcctggctatgggcaggatgtccgcaagtggccacaaggggttgtcccccagctc
cagccttcagccccagcttccaatgagataaccacgacaccggagcggccccggcggggc
gtcccaggccttcctgacagccgtttccacctgcctccccggatccacagagcctctgat
ccgggtctgccagctgaggaacccaaggagaagtcctctcggaaagcgactgagcccgag
ctgatgggaacccccgatggcagctgctaccctccaccaccagtgcctagacaggcatca
ccccagaacctggggacccctggcctgctgcatccacagacctcacccctgctgcactcg
ctggtgggccagcatatcctgtccgtcaagcagttcaccaaggatcagatgtctcacctg
ttcaatgttgcgcacaccctgaggatgatggtgcagaaggagcggagcctggacatcctc
aaggggaaggtcatggcttccatgttctatgaggtgagcacgcggaccagcagctccttt
gcagcagccatggcccggctagggggctcagtgctcagcttctctgaggccacgtcctcc
gtacagaagggggagtcgctggcagactcagtgcagaccatgagctgctacgctgacgtt
gtggtgcttcggcacccccagcctggcgctgtggagctggcggccaagcactgccggaga
ccagtaatcaacgcaggggatggggtcggtgagcaccccacacaggccctactggacatc
ttcaccattcgggaggagctgggcaccgtcaacggcatgacgatcaccatggtgggggac
ctgaagcacgggcgcacggtgcactcgctcgcttgcctgctcacccagtaccgcgtcagc
ctgcgctacgtggcgcctcccagcctacgcatgccacccaacgtgtgggacttcgtggcc
tcccgtggcaccaagcaggaggagtttgagagcatcgaggaggcactgcctgacactgat
gtgctctacatgacccggatccagaaggagcggttcggttccacccaagagtatgaatct
tgctttggtcagttcatcatcactccccacatcatgacccgagccaagaagaagatggtg
gtgatgcaccccatgccccgagtcaacgagatcagcgtggaggtggactcagatccccgg
gctgcctacttccgccaggctgagaacggcatgtacatccgcatggctctgttggccacc
gtgctgggccgtttctag

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