KEGG   PATHWAY: osa00591
Entry
osa00591                    Pathway                                
Name
Linoleic acid metabolism - Oryza sativa japonica (Japanese rice) (RefSeq)
Class
Metabolism; Lipid metabolism
Pathway map
osa00591  Linoleic acid metabolism
osa00591

Other DBs
GO: 0043651
Organism
Oryza sativa japonica (Japanese rice) (RefSeq) [GN:osa]
Gene
4333862  phospholipase A2 homolog 3 [KO:K01047] [EC:3.1.1.4]
4334536  triacylglycerol lipase SDP1 [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
4327023  triacylglycerol lipase SDP1 [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
4333823  probable linoleate 9S-lipoxygenase 4 isoform X1 [KO:K15718] [EC:1.13.11.58]
4350766  putative linoleate 9S-lipoxygenase 3 [KO:K15718] [EC:1.13.11.58]
4334049  linoleate 9S-lipoxygenase 2 [KO:K15718] [EC:1.13.11.58]
4333818  linoleate 9S-lipoxygenase 1 [KO:K15718] [EC:1.13.11.58]
4333821  putative linoleate 9S-lipoxygenase 3 [KO:K15718] [EC:1.13.11.58]
4331824  probable lipoxygenase 6 [KO:K00454] [EC:1.13.11.12]
4328603  lipoxygenase 2.3, chloroplastic [KO:K00454] [EC:1.13.11.12]
4338358  linoleate 9S-lipoxygenase 6 [KO:K00454] [EC:1.13.11.12]
4345993  lipoxygenase 7, chloroplastic [KO:K00454] [EC:1.13.11.12]
4345994  probable lipoxygenase 8, chloroplastic [KO:K00454] [EC:1.13.11.12]
4352505  lipoxygenase 2.1, chloroplastic isoform X1 [KO:K00454] [EC:1.13.11.12]
4352509  lipoxygenase 2.1, chloroplastic [KO:K00454] [EC:1.13.11.12]
9267158  putative lipoxygenase 5 [KO:K00454] [EC:1.13.11.12]
Compound
C00157  Phosphatidylcholine
C00219  Arachidonate
C01595  Linoleate
C03242  Dihomo-gamma-linolenate
C04056  Rumenic acid
C04717  (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoic acid
C06426  (6Z,9Z,12Z)-Octadecatrienoic acid
C07289  Crepenynate
C07338  (9Z,12Z)-(11S)-11-Hydroperoxyoctadeca-9,12-dienoic acid
C07354  (7S,8S)-DiHODE
C14762  13(S)-HODE
C14765  13-OxoODE
C14766  9-OxoODE
C14767  9(S)-HODE
C14825  9(10)-EpOME
C14826  12(13)-EpOME
C14827  9(S)-HPODE
C14828  9,10-DHOME
C14829  12,13-DHOME
C14831  8(R)-HPODE
C14832  12,13-Epoxy-9-hydroxy-10-octadecenoate
C14833  9,12,13-TriHOME
C14834  9,10-Epoxy-13-hydroxy-11-octadecenoate
C14835  9,10,13-TriHOME
C14836  9,10-12,13-Diepoxyoctadecanoate
C14837  9,10-Dihydroxy-12,13-epoxyoctadecanoate
C19937  (8E,10R,12Z)-10-Hydroperoxy-8,12-octadecadienoate
C20186  5S,8R-DiHODE
Reference
  Authors
Nowak G, Grant DF, Moran JH.
  Title
Linoleic acid epoxide promotes the maintenance of mitochondrial function and active Na+ transport following hypoxia.
  Journal
Toxicol Lett 147:161-75 (2004)
DOI:10.1016/j.toxlet.2003.11.002
Reference
  Authors
Shureiqi I, Jiang W, Zuo X, Wu Y, Stimmel JB, Leesnitzer LM, Morris JS, Fan HZ, Fischer SM, Lippman SM.
  Title
The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells.
  Journal
Proc Natl Acad Sci U S A 100:9968-73 (2003)
DOI:10.1073/pnas.1631086100
Reference
  Authors
Spiteller G.
  Title
Do changes in the cell membrane structure induce the generation of lipid peroxidation products which serve as first signalling molecules in cell to cell communication?
  Journal
Prostaglandins Leukot Essent Fatty Acids 67:151-62 (2002)
DOI:10.1054/plef.2002.0413
Reference
  Authors
Jude AR, Little JM, Bull AW, Podgorski I, Radominska-Pandya A.
  Title
13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases.
  Journal
Drug Metab Dispos 29:652-5 (2001)
Reference
PMID:9694817
  Authors
Su C, Sahlin M, Oliw EH.
  Title
A protein radical and ferryl intermediates are generated by linoleate diol synthase, a ferric hemeprotein with dioxygenase and hydroperoxide isomerase activities.
  Journal
J Biol Chem 273:20744-51 (1998)
DOI:10.1074/jbc.273.33.20744
Reference
PMID:1634517
  Authors
Brodowsky ID, Hamberg M, Oliw EH.
  Title
A linoleic acid (8R)-dioxygenase and hydroperoxide isomerase of the fungus Gaeumannomyces graminis. Biosynthesis of (8R)-hydroxylinoleic acid and (7S,8S)-dihydroxylinoleic acid from (8R)-hydroperoxylinoleic acid.
  Journal
J Biol Chem 267:14738-45 (1992)
Reference
  Authors
Hamberg M, Hamberg G.
  Title
Peroxygenase-Catalyzed Fatty Acid Epoxidation in Cereal Seeds (Sequential Oxidation of Linoleic Acid into 9(S),12(S),13(S)-Trihydroxy-10(E)-Octadecenoic Acid).
  Journal
Plant Physiol 110:807-815 (1996)
DOI:10.1104/pp.110.3.807
Reference
PMID:8765137
  Authors
Moghaddam M, Motoba K, Borhan B, Pinot F, Hammock BD.
  Title
Novel metabolic pathways for linoleic and arachidonic acid metabolism.
  Journal
Biochim Biophys Acta 1290:327-39 (1996)
DOI:10.1016/0304-4165(96)00037-2
Related
pathway
osa00590  Arachidonic acid metabolism
KO pathway
ko00591   
LinkDB

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