KEGG   Pteropus alecto (black flying fox): 102888822
Entry
102888822         CDS       T02993                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale04010  MAPK signaling pathway
pale04015  Rap1 signaling pathway
pale04218  Cellular senescence
pale04380  Osteoclast differentiation
pale04620  Toll-like receptor signaling pathway
pale04664  Fc epsilon RI signaling pathway
pale04668  TNF signaling pathway
pale04750  Inflammatory mediator regulation of TRP channels
pale04912  GnRH signaling pathway
pale04935  Growth hormone synthesis, secretion and action
pale04936  Alcoholic liver disease
pale05014  Amyotrophic lateral sclerosis
pale05022  Pathways of neurodegeneration - multiple diseases
pale05132  Salmonella infection
pale05135  Yersinia infection
pale05145  Toxoplasmosis
pale05161  Hepatitis B
pale05163  Human cytomegalovirus infection
pale05167  Kaposi sarcoma-associated herpesvirus infection
pale05169  Epstein-Barr virus infection
pale05170  Human immunodeficiency virus 1 infection
pale05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pale05417  Lipid and atherosclerosis
pale05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pale00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102888822 (MAP2K6)
   04015 Rap1 signaling pathway
    102888822 (MAP2K6)
   04668 TNF signaling pathway
    102888822 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    102888822 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102888822 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    102888822 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102888822 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    102888822 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102888822 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102888822 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102888822 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102888822 (MAP2K6)
   05161 Hepatitis B
    102888822 (MAP2K6)
   05163 Human cytomegalovirus infection
    102888822 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102888822 (MAP2K6)
   05169 Epstein-Barr virus infection
    102888822 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102888822 (MAP2K6)
   05135 Yersinia infection
    102888822 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102888822 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102888822 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    102888822 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102888822 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    102888822 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102888822 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pale01001]
    102888822 (MAP2K6)
Enzymes [BR:pale01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102888822 (MAP2K6)
Protein kinases [BR:pale01001]
 Serine/threonine kinases: STE group
  STE7 family
   102888822 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 102888822
NCBI-ProteinID: XP_006912331
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLIIGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaggaagcattt
gaacagcctcagaccagttccacgccacctcgagatttagactccaaagcgtgcatttct
attggaaatcagaactttgaggtgaaggcggatgacctggaacctataatggagctggga
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacggtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtccttttacggtcaccttttatggcgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacatcgctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcatcgagatgtc
aagccttccaacgtgctgatcaatactctgggccaggtgaagatgtgcgattttggaatc
agtggctacctggtagactccgtcgctaaaacgattgatgcaggatgcaaaccatacatg
gcccctgagagaataaacccagagctcaaccagaagggctacagcgtgaagtctgacatt
tggagtctgggcataacgatgattgagttggccatccttcggtttccctacgattcatgg
ggaactccctttcagcagctcaaacaagtagtagaggagccgtcgccacagctcccagca
gacaagttctccgaagagttcgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggccaacgtatccagagcttatgcaacatccatttttcaccctacatgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattattggagactaa

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