Paenisporosarcina antarctica: E2636_02145
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Entry
E2636_02145 CDS
T05927
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
panc
Paenisporosarcina antarctica
Pathway
panc00300
Lysine biosynthesis
panc00550
Peptidoglycan biosynthesis
panc01100
Metabolic pathways
panc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
panc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
E2636_02145
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
E2636_02145
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
E2636_02145
Enzymes [BR:
panc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
E2636_02145
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PH_39
DUF7623
Motif
Other DBs
NCBI-ProteinID:
QBP40036
UniProt:
A0A4P6ZX14
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Position
418347..419723
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AA seq
458 aa
AA seq
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MKKSLRTIAKWLNIDTLETSDVMVSGVSINTKTIQPGDLFIPFKGDKVNGHQYVDQAFEK
GASATLWQQDEPNPPRNVPILFVEDSEKALQQMARSYRKEHRATFIGITGSNGKTSTKDL
VAGVLAPYFRVQKTAGNFNNNLGLPITILSLDEDTEFAVLEMGMSGYGEIEFLSTLAEPH
YVAITNIGEAHMQDLGSRDGIVKAKFEIVAGLQEGGCLFYDGDEPLLNPFIQQFNLENVT
STIKTISFGANSSNDVYAQSIQATENGSEFDVKGLIEDHFMIPVLGKHQVKNALVAILIA
QKAGLTNKQIHDSLKKSSLTDMRMQVIHAENGSLFINDAYNAAPTSMKAAITFICETTIR
PDKWLVLGDMLELGDDEQIYHEELADQIKSQDFSGVCLYGPRMKWLYEKLQHKFADTHVI
WSEKDYEPIRVTLKTYTTLNSIVLVKGSRGMALENVIK
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
ttgaaaaaatcactacgaacaattgccaaatggctaaacatagatacgttagaaacatca
gatgtaatggtaagtggtgtctcaatcaatacaaaaaccattcaacctggtgacttgttt
atcccctttaaaggagataaagtaaatggtcaccaatatgtagaccaggcctttgaaaaa
ggagcgtctgctactctttggcaacaagatgagccgaatcccccgagaaatgtgccaatt
ctttttgttgaagacagtgaaaaggctctgcaacaaatggctcgttcatatcgcaaagaa
catcgagcgacgttcatcggaattacaggttcaaatggcaagacttctacaaaggattta
gtagcgggtgttctcgctccttatttccgcgttcaaaaaacagcaggtaattttaataat
aatttaggcttacccattaccattttgtctttagatgaagatactgaatttgcagtgctt
gaaatggggatgagtggttatggagaaatcgagtttttatccactctagcagaaccacat
tacgttgctattacaaacattggggaagcgcatatgcaagacttggggtctcgagatgga
attgtaaaggccaagtttgaaatcgttgcaggcttacaagagggaggttgtttattttat
gatggagatgaacccctacttaatccattcatccaacaattcaacctcgagaatgtaact
tctactattaaaacaatttcatttggtgctaacagttcaaatgacgtttacgcgcaatcg
attcaagctacggaaaatggtagtgaatttgatgtgaagggattaattgaagatcatttt
atgattcctgttttaggaaagcatcaagttaaaaatgcattagtcgctattttaattgca
caaaaagcaggcttaaccaacaaacagattcacgactctttgaaaaaatcgtcactaaca
gatatgcgcatgcaagtaatacatgcagaaaatggttcgttatttattaatgatgcgtat
aatgctgctccgacatcaatgaaggctgcaatcactttcatttgtgaaacaaccattcga
ccagataaatggcttgtactcggtgatatgttggagctaggtgatgatgagcaaatttat
catgaagaattggctgatcaaatcaagtcacaagatttctcaggcgtctgtttatatggt
ccgagaatgaaatggttgtatgaaaagttgcaacataagtttgcggacactcatgtgatt
tggtcagaaaaagactatgaaccgattcgagttactttaaaaacctatactactttaaac
tccatcgttttagtaaaaggctctcgcgggatggcacttgaaaacgttataaagtaa
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