KEGG   PATHWAY: bacb01054
Entry
bacb01054                   Pathway                                
Name
Nonribosomal peptide structures - Bacillus sp. BH072
Class
Metabolism; Metabolism of terpenoids and polyketides
Pathway map
bacb01054  Nonribosomal peptide structures
bacb01054

Organism
Bacillus sp. BH072 [GN:bacb]
Gene
OY17_04495  peptide synthetase [KO:K15654]
OY17_04500  peptide synthetase [KO:K15655]
OY17_04505  peptide synthetase [KO:K15656]
OY17_12225  peptide synthetase [KO:K15661]
OY17_12220  peptide synthetase [KO:K15662]
OY17_12215  peptide synthetase [KO:K15663]
OY17_12355  peptide synthetase [KO:K15666]
OY17_12350  peptide synthetase [KO:K15667]
OY17_12345  ATP-dependent isoleucine adenylase [KO:K15668]
OY17_12365  peptide synthetase [KO:K15664]
OY17_12360  peptide synthetase [KO:K15665]
Compound
C00065  L-Serine
C01540  Viomycin
C01895  Bleomycin B2
C05371  Microcystin LR
C11218  Gramicidin S
C11615  Pristinamycin IA
C12030  Mycosubtilin
C12041  Tyrocidine
C12042  Fengycin
C12043  Surfactin
C12265  Lichenysin D
C12266  Iturin A
C12267  Bacillomycin D
C12268  Syringomycin
C15482  Bacitracin A
C18618  Aminomalonyl-[acp]
C22668  Colibactin
Reference
PMID:9864322
  Authors
Konz D, Doekel S, Marahiel MA.
  Title
Molecular and biochemical characterization of the protein template controlling biosynthesis of the lipopeptide lichenysin.
  Journal
J Bacteriol 181:133-40 (1999)
DOI:10.1128/JB.181.1.133-140.1999
Reference
  Authors
Moyne AL, Cleveland TE, Tuzun S.
  Title
Molecular characterization and analysis of the operon encoding the antifungal lipopeptide bacillomycin D.
  Journal
FEMS Microbiol Lett 234:43-9 (2004)
DOI:10.1016/j.femsle.2004.03.011
Reference
PMID:9830033
  Authors
Guenzi E, Galli G, Grgurina I, Gross DC, Grandi G.
  Title
Characterization of the syringomycin synthetase gene cluster. A link between prokaryotic and eukaryotic peptide synthetases.
  Journal
J Biol Chem 273:32857-63 (1998)
DOI:10.1074/jbc.273.49.32857
Reference
PMID:9303382
  Authors
de Crecy-Lagard V, Saurin W, Thibaut D, Gil P, Naudin L, Crouzet J, Blanc V
  Title
Streptogramin B biosynthesis in Streptomyces pristinaespiralis and Streptomyces virginiae: molecular characterization of the last structural peptide synthetase gene.
  Journal
Antimicrob Agents Chemother 41:1904-9 (1997)
DOI:10.1128/AAC.41.9.1904
Reference
  Authors
Du L, Sanchez C, Chen M, Edwards DJ, Shen B.
  Title
The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase.
  Journal
Chem Biol 7:623-42 (2000)
DOI:10.1016/S1074-5521(00)00011-9
Reference
  Authors
Rouhiainen L, Vakkilainen T, Siemer BL, Buikema W, Haselkorn R, Sivonen K
  Title
Genes coding for hepatotoxic heptapeptides (microcystins) in the cyanobacterium Anabaena strain 90.
  Journal
Appl Environ Microbiol 70:686-92 (2004)
DOI:10.1128/AEM.70.2.686-692.2004
Reference
  Authors
Trauger JW, Kohli RM, Mootz HD, Marahiel MA, Walsh CT.
  Title
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase.
  Journal
Nature 407:215-8 (2000)
DOI:10.1038/35025116
KO pathway
ko01054   
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