KEGG   PATHWAY: bna00290
Entry
bna00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Brassica napus (rape)
Class
Metabolism; Amino acid metabolism
Pathway map
bna00290  Valine, leucine and isoleucine biosynthesis
bna00290

Module
bna_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bna00290]
bna_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bna00290]
bna_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bna00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Brassica napus (rape) [GN:bna]
Gene
106349704  threonine dehydratase biosynthetic, chloroplastic [KO:K01754] [EC:4.3.1.19]
106346190  threonine dehydratase biosynthetic, chloroplastic-like [KO:K01754] [EC:4.3.1.19]
106439173  threonine dehydratase biosynthetic, chloroplastic-like [KO:K01754] [EC:4.3.1.19]
106427957  threonine dehydratase biosynthetic, chloroplastic-like [KO:K01754] [EC:4.3.1.19]
106388975  threonine dehydratase biosynthetic, chloroplastic [KO:K01754] [EC:4.3.1.19]
106410269  threonine dehydratase biosynthetic, chloroplastic [KO:K01754] [EC:4.3.1.19]
106433150  3-isopropylmalate dehydratase large subunit, chloroplastic [KO:K01703] [EC:4.2.1.33 4.2.1.35]
106426997  3-isopropylmalate dehydratase large subunit, chloroplastic-like [KO:K01703] [EC:4.2.1.33 4.2.1.35]
106381416  3-isopropylmalate dehydratase large subunit, chloroplastic isoform X1 [KO:K01703] [EC:4.2.1.33 4.2.1.35]
106388413  3-isopropylmalate dehydratase large subunit, chloroplastic-like [KO:K01703] [EC:4.2.1.33 4.2.1.35]
106434492  3-isopropylmalate dehydratase small subunit 3 [KO:K01704] [EC:4.2.1.33 4.2.1.35]
106421017  3-isopropylmalate dehydratase small subunit 3-like [KO:K01704] [EC:4.2.1.33 4.2.1.35]
111203943  3-isopropylmalate dehydrogenase 2, chloroplastic-like [KO:K00052] [EC:1.1.1.85]
106398379  3-isopropylmalate dehydrogenase, chloroplastic [KO:K00052] [EC:1.1.1.85]
106354840  3-isopropylmalate dehydrogenase, chloroplastic-like [KO:K00052] [EC:1.1.1.85]
106398388  3-isopropylmalate dehydrogenase 2, chloroplastic-like [KO:K00052] [EC:1.1.1.85]
106398399  3-isopropylmalate dehydrogenase, chloroplastic-like [KO:K00052] [EC:1.1.1.85]
106430755  3-isopropylmalate dehydrogenase, chloroplastic-like [KO:K00052] [EC:1.1.1.85]
111197702  3-isopropylmalate dehydrogenase, chloroplastic [KO:K00052] [EC:1.1.1.85]
111203603  uncharacterized protein LOC111203603 [KO:K00052] [EC:1.1.1.85]
106350897  acetolactate synthase 3, chloroplastic-like [KO:K01652] [EC:2.2.1.6]
106353715  acetolactate synthase 1, chloroplastic [KO:K01652] [EC:2.2.1.6]
106353716  acetolactate synthase 3, chloroplastic [KO:K01652] [EC:2.2.1.6]
106366633  acetolactate synthase 1, chloroplastic [KO:K01652] [EC:2.2.1.6]
106366634  acetolactate synthase 1, chloroplastic [KO:K01652] [EC:2.2.1.6]
106408144  acetolactate synthase 3, chloroplastic-like [KO:K01652] [EC:2.2.1.6]
106354460  acetolactate synthase small subunit 1, chloroplastic [KO:K01653] [EC:2.2.1.6]
106355986  acetolactate synthase small subunit 1, chloroplastic-like [KO:K01653] [EC:2.2.1.6]
106363577  acetolactate synthase small subunit 1, chloroplastic isoform X1 [KO:K01653] [EC:2.2.1.6]
106448770  acetolactate synthase small subunit 2, chloroplastic-like [KO:K01653] [EC:2.2.1.6]
106430039  acetolactate synthase small subunit 2, chloroplastic-like [KO:K01653] [EC:2.2.1.6]
106447002  acetolactate synthase small subunit 2, chloroplastic isoform X1 [KO:K01653] [EC:2.2.1.6]
106437715  acetolactate synthase small subunit 2, chloroplastic-like [KO:K01653] [EC:2.2.1.6]
106451340  acetolactate synthase small subunit 2, chloroplastic-like [KO:K01653] [EC:2.2.1.6]
106387990  acetolactate synthase small subunit 2, chloroplastic-like [KO:K01653] [EC:2.2.1.6]
106380488  acetolactate synthase small subunit 2, chloroplastic [KO:K01653] [EC:2.2.1.6]
106353183  ketol-acid reductoisomerase, chloroplastic [KO:K00053] [EC:1.1.1.86]
106368280  ketol-acid reductoisomerase, chloroplastic-like isoform X2 [KO:K00053] [EC:1.1.1.86]
106368142  ketol-acid reductoisomerase, chloroplastic-like [KO:K00053] [EC:1.1.1.86]
106428249  ketol-acid reductoisomerase, chloroplastic-like [KO:K00053] [EC:1.1.1.86]
106396158  ketol-acid reductoisomerase, chloroplastic-like [KO:K00053] [EC:1.1.1.86]
106415217  ketol-acid reductoisomerase, chloroplastic-like [KO:K00053] [EC:1.1.1.86]
106452467  dihydroxy-acid dehydratase, chloroplastic [KO:K01687] [EC:4.2.1.9]
106451505  dihydroxy-acid dehydratase, chloroplastic [KO:K01687] [EC:4.2.1.9]
106450576  dihydroxy-acid dehydratase, chloroplastic-like isoform X1 [KO:K01687] [EC:4.2.1.9]
106432460  dihydroxy-acid dehydratase, chloroplastic-like [KO:K01687] [EC:4.2.1.9]
106347397  branched-chain-amino-acid aminotransferase 3, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
106360576  branched-chain-amino-acid aminotransferase 3, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
106346160  branched-chain-amino-acid aminotransferase 6 [KO:K00826] [EC:2.6.1.42]
106362399  branched-chain-amino-acid aminotransferase 1, mitochondrial-like isoform X1 [KO:K00826] [EC:2.6.1.42]
106362401  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
106346218  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
106346221  branched-chain-amino-acid aminotransferase 1, mitochondrial-like isoform X1 [KO:K00826] [EC:2.6.1.42]
106350617  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
106350639  branched-chain-amino-acid aminotransferase 1, mitochondrial isoform X1 [KO:K00826] [EC:2.6.1.42]
106439120  branched-chain-amino-acid aminotransferase 6 [KO:K00826] [EC:2.6.1.42]
106410712  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
106443896  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
106453117  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
106453118  branched-chain-amino-acid aminotransferase 1, mitochondrial-like isoform X1 [KO:K00826] [EC:2.6.1.42]
106380604  branched-chain-amino-acid aminotransferase 3, chloroplastic isoform X1 [KO:K00826] [EC:2.6.1.42]
106442104  branched-chain-amino-acid aminotransferase 6-like [KO:K00826] [EC:2.6.1.42]
106385095  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
106418519  branched-chain-amino-acid aminotransferase 3, chloroplastic [KO:K00826] [EC:2.6.1.42]
106407480  branched-chain-amino-acid aminotransferase 1, mitochondrial-like isoform X1 [KO:K00826] [EC:2.6.1.42]
106419827  branched-chain-amino-acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
106346910  2-isopropylmalate synthase 1, chloroplastic-like [KO:K01649] [EC:2.3.3.13]
106369058  2-isopropylmalate synthase 1, chloroplastic-like [KO:K01649] [EC:2.3.3.13]
106436775  2-isopropylmalate synthase 1, chloroplastic-like [KO:K01649] [EC:2.3.3.13]
106427153  2-isopropylmalate synthase 1, chloroplastic [KO:K01649] [EC:2.3.3.13]
106421092  3-isopropylmalate dehydratase small subunit 1 [KO:K21359] [EC:4.2.1.33 4.2.1.170]
106434491  3-isopropylmalate dehydratase small subunit 1 [KO:K21359] [EC:4.2.1.33 4.2.1.170]
106388301  LOW QUALITY PROTEIN: 3-isopropylmalate dehydratase small subunit 1 [KO:K21359] [EC:4.2.1.33 4.2.1.170]
106367226  3-isopropylmalate dehydrogenase 3, chloroplastic [KO:K21360] [EC:1.1.1.85 1.1.1.-]
106379685  3-isopropylmalate dehydrogenase 3, chloroplastic isoform X1 [KO:K21360] [EC:1.1.1.85 1.1.1.-]
106429911  3-isopropylmalate dehydrogenase 3, chloroplastic isoform X1 [KO:K21360] [EC:1.1.1.85 1.1.1.-]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
bna00260  Glycine, serine and threonine metabolism
bna00280  Valine, leucine and isoleucine degradation
bna00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

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