KEGG   PATHWAY: bsu00230
Entry
bsu00230                    Pathway                                
Name
Purine metabolism - Bacillus subtilis subsp. subtilis 168
Class
Metabolism; Nucleotide metabolism
Pathway map
bsu00230  Purine metabolism
bsu00230

Module
bsu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bsu00230]
bsu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bsu00230]
bsu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bsu00230]
bsu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bsu00230]
bsu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bsu00230]
Other DBs
GO: 0006163 0042278
Organism
Bacillus subtilis subsp. subtilis 168 [GN:bsu]
Gene
BSU23610  nudF; adp-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BSU23500  drm; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
BSU09310  pgcA; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BSU00510  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BSU06490  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BSU06530  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BSU06510  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BSU02230  purT; phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
BSU06480  purL; phosphoribosylformylglycinamidine synthase [KO:K23269] [EC:6.3.5.3]
BSU06460  purS; hypothetical protein [KO:K23264] [EC:6.3.5.3]
BSU06470  purQ; phosphoribosylformylglycinamidine synthase [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BSU06500  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BSU06430  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
BSU06420  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
BSU06450  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BSU06440  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BSU06520  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BSU27610  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BSU23490  pupG; purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
BSU19630  deoD; purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
BSU15370  ylmD; laccase domain protein YlmD [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BSU00680  hprT; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BSU00090  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BSU22730  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BSU28360  ysnA; non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
BSU22070  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
BSU32470  pucE; xanthine dehydrogenase subunit E [KO:K00087] [EC:1.17.1.4]
BSU32490  pucC; xanthine dehydrogenase subunit C [KO:K00087] [EC:1.17.1.4]
BSU32510  pucA; xanthine dehydrogenase subunit A [KO:K00087] [EC:1.17.1.4]
BSU32480  pucD; xanthine dehydrogenase subunit D [KO:K00087] [EC:1.17.1.4]
BSU06360  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
BSU32130  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
BSU13170  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BSU15680  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BSU17380  nrdE; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BSU20060  nrdEB; ribonucleoside-diphosphate reductase NrdEB subunit alpha [KO:K00525] [EC:1.17.4.1]
BSU17390  nrdF; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BSU20040  nrdF; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BSU00150  dgk; deoxyguanosine kinase [KO:K15518] [EC:2.7.1.113]
BSU27600  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BSU11600  yjbM; GTP pyrophosphokinase YjbM [KO:K07816] [EC:2.7.6.5]
BSU38480  ywaC; GTP pyrophosphokinase YwaC [KO:K07816] [EC:2.7.6.5]
BSU40420  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BSU00140  dck; deoxyadenosine/deoxycytidine kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
BSU14520  adeC; adenine deaminase [KO:K01486] [EC:3.5.4.2]
BSU06560  yerA; adenine deaminase YerA [KO:K01486] [EC:3.5.4.2]
BSU07840  yfkN; nucleotide phosphoesterase [KO:K08693] [EC:3.1.4.16 3.1.3.6 3.1.3.5]
BSU16970  ymdB; hypothetical protein [KO:K09769] [EC:3.1.4.16]
BSU01370  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BSU15600  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
BSU10910  yisZ; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
BSU10920  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
BSU15590  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
BSU32450  pucL; urate oxidase with peroxide reductase N-terminal domain [KO:K16838] [EC:1.7.3.3 4.1.1.97]
BSU32460  pucM; 5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BSU32410  pucH; allantoinase [KO:K01466] [EC:3.5.2.5]
BSU32530  yurH; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
BSU32520  pucG; purine catabolism protein PucG [KO:K00839] [EC:2.6.1.112]
BSU36640  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BSU36650  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
BSU36660  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bsu00030  Pentose phosphate pathway
bsu00220  Arginine biosynthesis
bsu00250  Alanine, aspartate and glutamate metabolism
bsu00260  Glycine, serine and threonine metabolism
bsu00340  Histidine metabolism
bsu00630  Glyoxylate and dicarboxylate metabolism
bsu00730  Thiamine metabolism
bsu00740  Riboflavin metabolism
bsu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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