KEGG   PATHWAY: rn00040
Entry
rn00040                     Pathway                                
Name
Pentose and glucuronate interconversions
Class
Metabolism; Carbohydrate metabolism
Pathway map
rn00040  Pentose and glucuronate interconversions
rn00040

Module
M00014  Glucuronate pathway (uronate pathway) [PATH:rn00040]
M00061  D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:rn00040]
M00081  Pectin degradation [PATH:rn00040]
M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:rn00040]
M00630  D-Galacturonate degradation (fungi), D-galacturonate => glycerol [PATH:rn00040]
M00631  D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:rn00040]
Reaction
R00264  2,5-dioxopentanoate:NADP+ 5-oxidoreductase
R00286  UDP-glucose:NAD+ 6-oxidoreductase
R00289  UTP:alpha-D-glucose-1-phosphate uridylyltransferase
R01381  UTP:1-phospho-alpha-D-glucuronate uridylyltransferase
R01383  UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)
R01429  D-xylose:NAD+ 1-oxidoreductase
R01430  D-xylose:NADP+ 1-oxidoreductase
R01431  xylitol:NADP+ oxidoreductase
R01432  D-xylose aldose-ketose-isomerase
R01476  ATP:D-glucuronate 1-phosphotransferase
R01478  beta-D-glucuronoside glucuronosohydrolase
R01481  L-gulonate:NADP+ 6-oxidoreductase
R01482  D-glucuronate aldose-ketose-isomerase
R01524  D-Ribitol-5-phosphate:NAD+ 2-oxidoreductase
R01525  D-Ribitol-5-phosphate:NADP+ 2-oxidoreductase
R01526  ATP:D-ribulose 5-phosphotransferase
R01529  D-Ribulose-5-phosphate 3-epimerase
R01540  D-altronate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)
R01542  2-Dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase
R01577  D-arabinose aldose-ketose-isomerase
R01639  ATP:D-xylulose 5-phosphotransferase
R01758  L-Arabitol:NAD+ 1-oxidoreductase
R01759  L-Arabitol:NADP+ 1-oxidoreductase
R01761  L-Arabinose aldose-ketose-isomerase
R01782  2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase (pyruvate-forming)
R01785  L-xylulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming)
R01892  Ribitol:ferricytochrome-c 2-oxidoreductase
R01895  Ribitol:NAD+ 2-oxidoreductase
R01896  xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming)
R01898  D-lyxose aldose-ketose-isomerase
R01901  ATP:L-xylulose 5-phosphotransferase
R01902  ATP:L-xylulose 1-phosphotransferase
R01903  L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming)
R01904  Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming)
R01905  3-Dehydro-L-gulonate carboxy-lyase
R01906  L-lyxose aldose-ketose-isomerase
R01982  Poly(1,4-alpha-D-galacturonate) galacturonohydrolase
R01983  D-Galacturonate aldose-ketose-isomerase
R02360  poly(1,4-alpha-D-galacturonate) glycanohydrolase
R02361  (1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase
R02362  Pectin pectylhydrolase
R02427  D-xylono-1,5-lactone lactonohydrolase
R02428  D-Xylono-1,4-lactone lactonohydrolase
R02429  D-Xylonate hydro-lyase
R02439  ATP:L-ribulose 5-phosphotransferase
R02441  L-Arabitol:NAD+ 2-oxidoreductase (L-ribulose-forming)
R02454  D-Mannonate:NAD+ 5-oxidoreductase
R02555  D-Altronate:NAD+ 3-oxidoreductase
R02637  3-Dehydro-L-gulonate:NAD+ 2-oxidoreductase
R02639  3-Dehydro-L-gulonate:NADP+ 2-oxidoreductase
R02640  L-Gulonate:NAD+ 3-oxidoreductase
R02921  CTP:D-ribitol-5-phosphate cytidylyltransferase
R03244  L-ribulose-5-phosphate 3-epimerase
R04382  4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate lyase
R04383  5-Dehydro-4-deoxy-D-glucuronate ketol-isomerase
R04515   
R04784   
R05604  D-arabinitol:NAD 4-oxidoreductase
R05606  D-mannonate hydro-lyase
R05831  xylitol:NAD oxidoreductase
R05850  L-ribulose-5-phosphate 4-epimerase
R07125  3-dehydro-L-gulonate-6-phosphate carboxy-lyase
R07127  ATP:3-dehydro-L-gulonate 6-phosphotransferase
R07134  D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming)
R07143  D-arabinitol:NADP+ oxidoreductase
R07144  D-arabinitol:NADP+ oxidoreductase
R07152  xylitol:oxygen oxidoreductase
R07413   
R07676  L-galactonate:NADP+ oxidoreductase
R09186  2-dehydro-3-deoxy-D-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)
R09477  xylitol:NAD+ oxidoreductase
R10532  L-galactonate hydro-lyase (2-dehydro-3-deoxy-L-galactonate-forming)
R10550  2-dehydro-3-deoxy-L-galactonate L-glyceraldehyde-lyase (pyruvate-forming)
R10563  glycerol:NADP+ oxidoreductase (D/L-glyceraldehyde-forming)
R10565  L-galactonate:NAD+ oxidoreductase
R10848  L-gulonate:NAD+ 5-oxidoreductase
R11624  D-tagaturonate 3-epimerase
R11768  2,5-dioxopentanoate:NAD+ 5-oxidoreductase
R12643  D-xylose:NADP+ 1-oxidoreductase (D-xylono-1,4-lactone-forming)
R12695  ATP:D-ribulose 1-phosphotransferase
R12696  D-ribulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming)
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00167  UDP-glucuronate
C00181  D-Xylose
C00191  D-Glucuronate
C00199  D-Ribulose 5-phosphate
C00204  2-Dehydro-3-deoxy-D-gluconate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00266  Glycolaldehyde
C00309  D-Ribulose
C00310  D-Xylulose
C00312  L-Xylulose
C00333  D-Galacturonate
C00379  Xylitol
C00433  2,5-Dioxopentanoate
C00470  Pectate
C00474  Ribitol
C00476  D-Lyxose
C00502  D-Xylonate
C00508  L-Ribulose
C00514  D-Mannonate
C00532  L-Arabitol
C00558  D-Tagaturonate
C00618  3-Dehydro-L-gulonate
C00714  Pectin
C00789  CDP-ribitol
C00800  L-Gulonate
C00817  D-Altronate
C00905  D-Fructuronate
C01068  D-Ribitol 5-phosphate
C01101  L-Ribulose 5-phosphate
C01508  L-Lyxose
C01904  D-Arabitol
C02266  D-Xylonolactone
C02273  Digalacturonate
C02426  L-Glyceraldehyde
C02753  D-Xylono-1,4-lactone
C03033  beta-D-Glucuronoside
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C04053  5-Dehydro-4-deoxy-D-glucuronate
C04349  (4S)-4,6-Dihydroxy-2,5-dioxohexanoate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C06118  4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate
C06441  L-Xylulose 1-phosphate
C14899  3-Dehydro-L-gulonate 6-phosphate
C15930  L-Galactonate
C20680  2-Dehydro-3-deoxy-L-galactonate
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Yew WS, Gerlt JA.
  Title
Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.
  Journal
J Bacteriol 184:302-6 (2002)
DOI:10.1128/JB.184.1.302-306.2002
Reference
  Authors
Yew WS, Akana J, Wise EL, Rayment I, Gerlt JA
  Title
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
  Journal
Biochemistry 44:1807-15 (2005)
DOI:10.1021/bi047815v
Reference
  Authors
Yasueda H, Kawahara Y, Sugimoto S.
  Title
Bacillus subtilis yckG and yckF encode two key enzymes of the ribulose monophosphate pathway used by methylotrophs, and yckH is required for their expression.
  Journal
J Bacteriol 181:7154-60 (1999)
DOI:10.1128/JB.181.23.7154-7160.1999
Reference
  Authors
Ibanez E, Gimenez R, Pedraza T, Baldoma L, Aguilar J, Badia J
  Title
Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose.
  Journal
J Bacteriol 182:4625-7 (2000)
DOI:10.1128/JB.182.16.4625-4627.2000
Reference
  Authors
Orita I, Yurimoto H, Hirai R, Kawarabayasi Y, Sakai Y, Kato N
  Title
The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway.
  Journal
J Bacteriol 187:3636-42 (2005)
DOI:10.1128/JB.187.11.3636-3642.2005
Related
pathway
rn00010  Glycolysis / Gluconeogenesis
rn00020  Citrate cycle (TCA cycle)
rn00030  Pentose phosphate pathway
rn00052  Galactose metabolism
rn00053  Ascorbate and aldarate metabolism
rn00500  Starch and sucrose metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn00561  Glycerolipid metabolism
rn00562  Inositol phosphate metabolism
rn00740  Riboflavin metabolism
KO pathway
ko00040   
LinkDB

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