KEGG   PATHWAY: rn00363
Entry
rn00363                     Pathway                                

Name
Bisphenol degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
rn00363  Bisphenol degradation
rn00363

Other DBs
UMBBD: tbp2 bpa hap bpf
Reaction
R01305  2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving)
R06876   
R06877   
R06878   
R06879   
R06880   
R06881   
R06882   
R06883   
R06884   
R06885   
R06886   
R06887   
R06888   
R06889   
R06890   
R06891   
R06892  (4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming)
R06893  aryl-ester hydrolase
R09102   
R09103   
R09104   
R09105   
Compound
C00156  4-Hydroxybenzoate
C00530  Hydroquinone
C00633  4-Hydroxybenzaldehyde
C10700  4'-Hydroxyacetophenone
C13620  Tetrabromobisphenol A
C13621  Tribromobisphenol A
C13622  Dibromobisphenol A
C13623  Monobromobisphenol A
C13624  Bisphenol A
C13625  4-Methyl-2,4-bis-(p-hydroxyphenyl)pent-1-ene
C13626  5-Hydroxybisphenol A
C13628  4,5-Bisphenol-o-quinone
C13629  1,2-Bis(4-hydroxyphenyl)-2-propanol
C13631  2,2-Bis(4-hydroxyphenyl)-1-propanol
C13632  4,4'-Dihydroxy-alpha-methylstilbene
C13633  2,2-Bis(4-hydroxyphenyl)-propanoic acid
C13634  2,3-Bis(4-hydroxyphenyl)-1,2-propanediol
C13635  4-Hydroxyphenacyl alcohol
C13636  4-Hydroxyphenyl acetate
C13637  4-Ethylphenol
C13638  1-(4'-Hydroxyphenyl)ethanol
C14220  4,4'-Dihydroxybenzophenone
C14298  Bis(4-hydroxyphenyl)methane
C18215  Bis(4-hydroxyphenyl)methanol
C18216  4-Hydroxyphenyl-4-hydroxybenzoate
Reference
  Authors
Kitamura S, Suzuki T, Sanoh S, Kohta R, Jinno N, Sugihara K, Yoshihara S, Fujimoto N, Watanabe H, Ohta S.
  Title
Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds.
  Journal
Toxicol Sci 84:249-59 (2005)
DOI:10.1093/toxsci/kfi074
Reference
PMID:9607780
  Authors
Steinmetz R, Mitchner NA, Grant A, Allen DL, Bigsby RM, Ben-Jonathan N.
  Title
The xenoestrogen bisphenol A induces growth, differentiation, and c-fos gene expression in the female reproductive tract.
  Journal
Endocrinology 139:2741-7 (1998)
DOI:10.1210/endo.139.6.6027
Reference
  Authors
Elsby R, Maggs JL, Ashby J, Park BK.
  Title
Comparison of the modulatory effects of human and rat liver microsomal metabolism on the estrogenicity of bisphenol A: implications for extrapolation to humans.
  Journal
J Pharmacol Exp Ther 297:103-13 (2001)
Reference
  Authors
Ronen Z, Abeliovich A.
  Title
Anaerobic-aerobic process for microbial degradation of tetrabromobisphenol A.
  Journal
Appl Environ Microbiol 66:2372-7 (2000)
DOI:10.1128/AEM.66.6.2372-2377.2000
Reference
  Authors
Eriksson J, Rahm S, Green N, Bergman A, Jakobsson E.
  Title
Photochemical transformations of tetrabromobisphenol A and related phenols in water.
  Journal
Chemosphere 54:117-26 (2004)
DOI:10.1016/S0045-6535(03)00704-5
Reference
  Authors
Ike M, Chen MY, Jin CS, Fujita M.
  Title
Acute toxicity, mutagenicity, and estrogenicity of biodegradation products of bisphenol-A.
  Journal
Environ Toxicol 17:457-61 (2002)
DOI:10.1002/tox.10079
Reference
PMID:8031091
  Authors
Jones KH, Trudgill PW, Hopper DJ
  Title
4-Ethylphenol metabolism by Aspergillus fumigatus.
  Journal
Appl Environ Microbiol 60:1978-83 (1994)
DOI:10.1128/AEM.60.6.1978-1983.1994
Reference
  Authors
Inoue D, Hara S, Kashihara M, Murai Y, Danzl E, Sei K, Tsunoi S, Fujita M, Ike M
  Title
Degradation of Bis(4-Hydroxyphenyl)methane (bisphenol F) by Sphingobium yanoikuyae strain FM-2 isolated from river water.
  Journal
Appl Environ Microbiol 74:352-8 (2008)
DOI:10.1128/AEM.01708-07
Related
pathway
rn00361  Chlorocyclohexane and chlorobenzene degradation
rn00362  Benzoate degradation
KO pathway
ko00363   
LinkDB

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