KEGG PATHWAY: rn00363

PATHWAY: rn00363

Entry

rn00363                     Pathway

Name

Bisphenol degradation

Class

Metabolism; Xenobiotics biodegradation and metabolism

Pathway map

rn00363

Bisphenol degradation

Other DBs

UMBBD:

tbp2 bpa hap bpf

Reaction

R01305

2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving)

R06876

R06877

R06878

R06879

R06880

R06881

R06882

R06883

R06884

R06885

R06886

R06887

R06888

R06889

R06890

R06891

R06892

(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming)

R06893

aryl-ester hydrolase

R09102

R09103

R09104

R09105

Compound

C00156

4-Hydroxybenzoate

C00530

Hydroquinone

C00633

4-Hydroxybenzaldehyde

C10700

4'-Hydroxyacetophenone

C13620

Tetrabromobisphenol A

C13621

Tribromobisphenol A

C13622

Dibromobisphenol A

C13623

Monobromobisphenol A

C13624

Bisphenol A

C13625

4-Methyl-2,4-bis-(p-hydroxyphenyl)pent-1-ene

C13626

5-Hydroxybisphenol A

C13628

4,5-Bisphenol-o-quinone

C13629

1,2-Bis(4-hydroxyphenyl)-2-propanol

C13631

2,2-Bis(4-hydroxyphenyl)-1-propanol

C13632

4,4'-Dihydroxy-alpha-methylstilbene

C13633

2,2-Bis(4-hydroxyphenyl)-propanoic acid

C13634

2,3-Bis(4-hydroxyphenyl)-1,2-propanediol

C13635

4-Hydroxyphenacyl alcohol

C13636

4-Hydroxyphenyl acetate

C13637

4-Ethylphenol

C13638

1-(4'-Hydroxyphenyl)ethanol

C14220

4,4'-Dihydroxybenzophenone

C14298

Bis(4-hydroxyphenyl)methane

C18215

Bis(4-hydroxyphenyl)methanol

C18216

4-Hydroxyphenyl-4-hydroxybenzoate

Reference

PMID:15635150

Authors

Kitamura S, Suzuki T, Sanoh S, Kohta R, Jinno N, Sugihara K, Yoshihara S, Fujimoto N, Watanabe H, Ohta S.

Title

Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds.

Journal

Toxicol Sci 84:249-59 (2005)
DOI:10.1093/toxsci/kfi074

Reference

PMID:9607780

Authors

Steinmetz R, Mitchner NA, Grant A, Allen DL, Bigsby RM, Ben-Jonathan N.

Title

The xenoestrogen bisphenol A induces growth, differentiation, and c-fos gene expression in the female reproductive tract.

Journal

Endocrinology 139:2741-7 (1998)
DOI:10.1210/endo.139.6.6027

Reference

PMID:11259533

Authors

Elsby R, Maggs JL, Ashby J, Park BK.

Title

Comparison of the modulatory effects of human and rat liver microsomal metabolism on the estrogenicity of bisphenol A: implications for extrapolation to humans.

Journal

J Pharmacol Exp Ther 297:103-13 (2001)

Reference

PMID:10831413

Authors

Ronen Z, Abeliovich A.

Title

Anaerobic-aerobic process for microbial degradation of tetrabromobisphenol A.

Journal

Appl Environ Microbiol 66:2372-7 (2000)
DOI:10.1128/AEM.66.6.2372-2377.2000

Reference

PMID:14559264

Authors

Eriksson J, Rahm S, Green N, Bergman A, Jakobsson E.

Title

Photochemical transformations of tetrabromobisphenol A and related phenols in water.

Journal

Chemosphere 54:117-26 (2004)
DOI:10.1016/S0045-6535(03)00704-5

Reference

PMID:12242676

Authors

Ike M, Chen MY, Jin CS, Fujita M.

Title

Acute toxicity, mutagenicity, and estrogenicity of biodegradation products of bisphenol-A.

Journal

Environ Toxicol 17:457-61 (2002)
DOI:10.1002/tox.10079

Reference

PMID:8031091

Authors

Jones KH, Trudgill PW, Hopper DJ

Title

4-Ethylphenol metabolism by Aspergillus fumigatus.

Journal

Appl Environ Microbiol 60:1978-83 (1994)
DOI:10.1128/AEM.60.6.1978-1983.1994

Reference

PMID:18024680

Authors

Inoue D, Hara S, Kashihara M, Murai Y, Danzl E, Sei K, Tsunoi S, Fujita M, Ike M

Title

Degradation of Bis(4-Hydroxyphenyl)methane (bisphenol F) by Sphingobium yanoikuyae strain FM-2 isolated from river water.

Journal

Appl Environ Microbiol 74:352-8 (2008)
DOI:10.1128/AEM.01708-07

Related
pathway

rn00361

Chlorocyclohexane and chlorobenzene degradation

rn00362

Benzoate degradation

KO pathway

ko00363

LinkDB

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