KEGG   PATHWAY: soe00965
Entry
soe00965                    Pathway                                
Name
Betalain biosynthesis - Spinacia oleracea (spinach)
Description
Betalains are water-soluble nitrogen-containing pigments that are present in plants belonging to the order Caryophyllales (such as cactus and amaranth families) and in higher fungi. They contain betalamic acid as the chromophore and are classified into two types: betacyanins and betaxanthins. Betacyanins contain a cyclo-DOPA residue and exhibit red/violet coloration, while betaxanthins contain different amino acids or amino side chains and exhibit a yellow/orange coloration. The condensation of betalamic acid with amino acids (including cyclo-DOPA or amines) in plants is a spontaneous reaction, not an enzyme-catalyzed reaction.
Class
Metabolism; Biosynthesis of other secondary metabolites
Pathway map
soe00965  Betalain biosynthesis
soe00965

Module
soe_M00961  Betacyanin biosynthesis, L-tyrosine => amaranthin [PATH:soe00965]
Organism
Spinacia oleracea (spinach) [GN:soe]
Gene
110786796  cytochrome P450 76AD1 [KO:K26037] [EC:1.14.-.-]
110786794  cytochrome P450 76AD1-like [KO:K26037] [EC:1.14.-.-]
110788024  cytochrome P450 76AD1-like [KO:K26037] [EC:1.14.-.-]
110779367  cytochrome P450 76AD1-like [KO:K26037] [EC:1.14.-.-]
110792889  cytochrome P450 76AD1-like [KO:K26037] [EC:1.14.-.-]
110779509  cytochrome P450 76AD1-like [KO:K26037] [EC:1.14.-.-]
110792903  cytochrome P450 76AD1-like [KO:K26037] [EC:1.14.-.-]
110788013  cytochrome P450 76AD1-like [KO:K26037] [EC:1.14.-.-]
110800072  4,5-DOPA dioxygenase extradiol 1-like [KO:K15777] [EC:1.13.11.-]
110786745  4,5-DOPA dioxygenase extradiol 1-like [KO:K15777] [EC:1.13.11.-]
110786746  4,5-DOPA dioxygenase extradiol 1-like [KO:K15777] [EC:1.13.11.-]
110775816  4,5-DOPA dioxygenase extradiol-like [KO:K15777] [EC:1.13.11.-]
110775828  4,5-DOPA dioxygenase extradiol [KO:K15777] [EC:1.13.11.-]
110775831  extradiol ring-cleavage dioxygenase-like [KO:K15777] [EC:1.13.11.-]
110797809  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
110797808  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
110778374  tyrosine decarboxylase 1 isoform X1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
110802302  tyrosine/DOPA decarboxylase 1-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
110787615  UDP-glycosyltransferase 92A1-like [KO:K15776] [EC:2.4.1.-]
110802367  scopoletin glucosyltransferase-like [KO:K15774] [EC:2.4.1.-]
110790831  scopoletin glucosyltransferase-like [KO:K15774] [EC:2.4.1.-]
110790835  scopoletin glucosyltransferase-like [KO:K15774] [EC:2.4.1.-]
110790832  scopoletin glucosyltransferase-like [KO:K15774] [EC:2.4.1.-]
110779263  scopoletin glucosyltransferase-like [KO:K15774] [EC:2.4.1.-]
110793183  scopoletin glucosyltransferase-like [KO:K15774] [EC:2.4.1.-]
110790833  scopoletin glucosyltransferase-like [KO:K15774] [EC:2.4.1.-]
110778564  UDP-glycosyltransferase 79B30-like [KO:K26038] [EC:2.4.1.-]
110784983  UDP-glycosyltransferase 79B30-like [KO:K26038] [EC:2.4.1.-]
110784981  UDP-glycosyltransferase 79B30-like [KO:K26038] [EC:2.4.1.-]
110804497  UDP-glycosyltransferase 79B30-like [KO:K26038] [EC:2.4.1.-]
110778064  anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase-like [KO:K26038] [EC:2.4.1.-]
110800421  anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase-like [KO:K26038] [EC:2.4.1.-]
110786383  UDP-glycosyltransferase 79B30-like [KO:K26038] [EC:2.4.1.-]
110778581  UDP-glycosyltransferase 79B30-like [KO:K26038] [EC:2.4.1.-]
110778543  anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase-like [KO:K26038] [EC:2.4.1.-]
110781882  anthocyanidin 3-O-glucosyltransferase 2-like [KO:K15775] [EC:2.4.1.-]
110784281  anthocyanidin 3-O-glucosyltransferase 2-like [KO:K15775] [EC:2.4.1.-]
Compound
C00082  L-Tyrosine
C00355  3,4-Dihydroxy-L-phenylalanine
C03758  Dopamine
C05587  3-Methoxytyramine
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C08537  Amaranthin
C08538  Betalamic acid
C08539  Betanidin
C08540  Betanin
C08542  Celosianin II
C08543  Dopaxanthin
C08544  Gomphrenin-I
C08552  Lampranthin II
C08557  Miraxanthin-V
C08565  Portulacaxanthin II
C17751  cyclo-Dopa 5-O-glucoside
C17752  cyclo-Dopa-glucuronylglucoside
C17753  Dopaxanthin quinone
C17754  3-Methoxytyramine-betaxanthin
C17755  Dopamine quinone
C17756  2-Descarboxy-cyclo-dopa
C17757  2-Descarboxy-betanidin
C17758  4,5-seco-Dopa
Reference
  Authors
Gandia-Herrero F, Escribano J, Garcia-Carmona F
  Title
Betaxanthins as substrates for tyrosinase. An approach to the role of tyrosinase in the biosynthetic pathway of betalains.
  Journal
Plant Physiol 138:421-32 (2005)
DOI:10.1104/pp.104.057992
Reference
  Authors
Sasaki N, Abe Y, Wada K, Koda T, Goda Y, Adachi T, Ozeki Y
  Title
Amaranthin in feather cockscombs is synthesized via glucuronylation at the cyclo-DOPA glucoside step in the betacyanin biosynthetic pathway.
  Journal
J Plant Res 118:439-42 (2005)
DOI:10.1007/s10265-005-0237-z
Reference
  Authors
Strack D, Vogt T, Schliemann W
  Title
Recent advances in betalain research.
  Journal
Phytochemistry 62:247-69 (2003)
DOI:10.1016/S0031-9422(02)00564-2
Reference
  Authors
Vogt T
  Title
Substrate specificity and sequence analysis define a polyphyletic origin of betanidin 5- and 6-O-glucosyltransferase from Dorotheanthus bellidiformis.
  Journal
Planta 214:492-5 (2002)
DOI:10.1007/s00425-001-0685-1
Related
pathway
soe00400  Phenylalanine, tyrosine and tryptophan biosynthesis
KO pathway
ko00965   
LinkDB

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