Prionailurus bengalensis (leopard cat): 122478869
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Entry
122478869 CDS
T07574
Symbol
KDR
Name
(RefSeq) vascular endothelial growth factor receptor 2
KO
K05098
kinase insert domain protein receptor [EC:
2.7.10.1
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg01521
EGFR tyrosine kinase inhibitor resistance
pbg04010
MAPK signaling pathway
pbg04014
Ras signaling pathway
pbg04015
Rap1 signaling pathway
pbg04020
Calcium signaling pathway
pbg04151
PI3K-Akt signaling pathway
pbg04370
VEGF signaling pathway
pbg04510
Focal adhesion
pbg04517
IgSF CAM signaling
pbg05205
Proteoglycans in cancer
pbg05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122478869 (KDR)
04014 Ras signaling pathway
122478869 (KDR)
04015 Rap1 signaling pathway
122478869 (KDR)
04370 VEGF signaling pathway
122478869 (KDR)
04020 Calcium signaling pathway
122478869 (KDR)
04151 PI3K-Akt signaling pathway
122478869 (KDR)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
122478869 (KDR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122478869 (KDR)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
122478869 (KDR)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
122478869 (KDR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122478869 (KDR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122478869 (KDR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pbg04090
]
122478869 (KDR)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122478869 (KDR)
Protein kinases [BR:
pbg01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
122478869 (KDR)
CD molecules [BR:
pbg04090
]
Proteins
122478869 (KDR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
VEGFR1-3_N_Ig-like
Ig_3
I-set
Pkinase
Ig_2
ig
VEGFR-1-like_Ig-like
Ig_VEGFR-1-like_5th
V-set
VEGFR-2_TMD
C2-set_2
Ig_4
Ig_PDGFR_d4
Haspin_kinase
BppU_N
ABC1
Motif
Other DBs
NCBI-GeneID:
122478869
NCBI-ProteinID:
XP_043428557
LinkDB
All DBs
Position
B1:162126657..162173357
Genome browser
AA seq
1356 aa
AA seq
DB search
MESKALLAVVLWFCVETGAASVGLPSVSLDPPRLSIQKDILTIMANTTLQITCRGQRDLD
WLWPNNQSGSEKRVEVTDCSDSFFCKTLTIPKVIGNDTGAYKCFYQDTDVASVIYVYVQD
YRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWD
SKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYKIYDVVLSPPHGVELSVGE
RLVLNCTARTELNVGIDFNWEYPSLKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRS
DQGWYTCAASSGLMTKRNSTFVRVHEKPFVAFGSGMESLVEAIVGDRVRVPVKYLGYPPP
EIKWYKNGRPIESNHTIKVGHVLTIMEVSEKDTGNYTVILTNPISKEKQSHVVSLVVNVP
PQIGEKSLISPVDSYQYGTTQTLTCTVYAVPPPHHIRWYWQLEEECAYRPAQAVLMTNPY
TCKEWRNVDDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKAGRGE
RVISFHVTRGPEITLQPGTQPTEQERVSLWCTADRTTFENLTWYKAGSQALPVHVGELRT
PICKNLDALWKMNATTFSNGTSDTLILELQNASLQDQGDYVCFAQDRKTKKRHCVVRQLM
VLERVAPMITGNLENQTTSIGETIEVSCTTSGNPPPQITWFKDNETLVEDSGIVLKDGNR
NLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIVEGAQEKTNLEVIILVGTAVIAMFFWL
LLVIVLRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPL
GRGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVN
LLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKEYVGEITMDPK
RRLDSITSSQSSASSGFVEEKSLSDVEEEEVSEDLYKNFLTLEHLICYSFQVAKGMEFLA
SRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDR
VYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTML
DCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVS
CMEEEEVCDPKFHYDNTAGISQYLQTSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDS
GMVLASEELKTLEDRTKLAPSFSGLMPSKSKESVASEGSNHTSGYQSGYHSDDTDTTVYS
SEEAELLKLVEIGPQAGSAAQILQPDSGPALGSPPV
NT seq
4071 nt
NT seq
+upstream
nt +downstream
nt
atggagagcaaggcgctcctggccgtcgttctgtggttctgcgtggagaccggggctgcc
tctgtgggtttgcctagtgtttcccttgatccacccagactcagcatacaaaaagacata
cttacaattatggctaatacgactcttcagattacttgcaggggacagagggacttggac
tggctctggcccaacaatcagagtggctctgagaagagagtggaggtgacggactgcagt
gacagcttcttctgtaagacgctcacaattccaaaagtgatcggaaatgatactggagcc
tacaagtgcttctaccaggacactgacgtagcctcggtcatttatgtctatgttcaagat
tacaggtctccatttattgcttctgttagcgaccaacatggcgttgtgtacatcactgag
aacaaaaacaaaactgtcgtgattccatgtcttgggtccatttccaacctcaatgtgtca
ctttgtgcaaggtatccagaaaagaggtttgtccctgatggtaacagaatttcctgggac
agtaagaaaggctttactatccccagctacatgatcagctatgctggcatggtcttctgt
gaagcaaaaattaatgatgaaagttaccagtctattatgtacatagttgtggttgtaggg
tacaagatttatgatgtggttctgagcccccctcatggagttgagctgtctgttggagag
aggctcgtcttaaactgtacagcgaggactgaactaaatgtggggattgacttcaactgg
gaatacccttctttgaagcatcagcataaaaagcttgttaaccgggacctaaaaactcaa
tctgggagtgagatgaagaaatttttgagcaccttgaccatagatggtgtaacccggagt
gaccaagggtggtatacctgtgcggcttccagtgggctgatgaccaagcggaacagcacg
ttcgtcagggtccacgaaaaaccttttgtcgcttttggcagtggcatggaatctttggtg
gaagccatcgtgggagaccgtgtcagagtgcctgtgaagtaccttggttaccctcccccg
gaaataaaatggtataaaaatgggagacccattgagtccaatcacacaataaaagtgggg
catgtactgactattatggaagtgagtgaaaaagatacaggaaattacactgtcatcctt
accaaccccatttcgaaggagaagcagagccacgtggtatctctggtcgtgaatgtcccc
ccccagatcggcgagaaatccctgatctctccggtggattcgtaccagtacggcaccacg
cagacgctgacgtgcacggtctacgcggtccctccgccacatcacatccgctggtactgg
cagctggaggaggagtgtgcctacaggcctgcccaagctgtcttaatgacaaacccatac
acttgtaaagaatggaggaatgtggatgacttccaggggggaaataaaattgaagtcaac
aaaaatcaatttgccctaattgaaggaaaaaacaaaactgtaagtacccttgttatccaa
gcggcaaatgtgtcagctttgtacaaatgtgaagccgtcaacaaagctgggagaggagag
agggttatctccttccacgtgaccaggggccctgaaatcacattgcagcccggcacccag
ccgaccgaacaggaacgggtgtctttgtggtgcactgcagacagaactacatttgagaac
ctcacgtggtacaaggctggctctcaggctctgccagtccacgtgggagagctgcgtaca
cccatctgcaagaacttggatgccctttggaaaatgaatgccaccacgttctctaatggc
acaagcgacactttgatcctggagctccagaacgcatccttgcaggaccaaggagattat
gtgtgctttgctcaggacaggaagaccaagaaaaggcattgtgtggtccgacagctcatg
gttttagaacgtgtggcacccatgatcacaggaaacctggagaatcaaacaacaagcatt
ggtgaaaccatcgaagtttcgtgcaccacgtctgggaatccccctccacagattacgtgg
tttaaagataatgaaacacttgttgaagactcaggtattgtactgaaagatgggaaccgg
aacctaaccatccgcagggtgaggaaggaagatgaaggcctgtatacctgccaggcatgc
agtgttcttgggtgtgcaaaagtggaggcatttttcatcgtagaaggtgcccaggagaag
accaacttggaggtcattattctagtaggcacagcagtgattgccatgttcttctggtta
ttacttgtcatcgttctacggaccgttaagcgggccaatggaggggaactgaagacaggc
tacttgtccatcgttatggatccagatgaactgcccttggatgaacactgtgaacgtttg
ccttatgatgccagcaagtgggaatttcccagagaccggctgaaactaggtaagcccctt
ggccgtggtgcctttggccaagtgatcgaagcagatgcctttggaattgacaagacagcg
acttgcaagacagtggctgtcaaaatgttaaaagaaggagccacacacagtgaacaccga
gccctcatgtctgaactcaagatcctcattcatattggccaccatctcaatgtggtcaat
cttctaggtgcctgtaccaagccaggagggccactcatggtgattgtggaattttgcaag
tttggaaacctgtcaacttacttaaggagcaagagaaatgaatttgtcccctacaagacc
aaaggggcacgatttcgtcaagggaaggaatacgttggggaaatcactatggatccgaaa
cgccgtttggatagtatcacgagtagtcagagctcagccagctctggatttgttgaggag
aaatccctcagtgatgtggaggaagaggaagtttctgaagatctgtacaagaacttcctg
accttggagcatctcatctgttacagcttccaagtggctaagggcatggagtttttggcg
tcacggaagtgtatccacagggacctggcggcacgaaatatcctcttgtcggagaagaac
gtggttaaaatctgtgactttggcttggcccgggatatttataaagatccagattatgtc
agaaaaggagatgctcgcctccctttgaaatggatggccccagaaacaatttttgaccga
gtgtacacaattcagagtgatgtgtggtcttttggtgttttgctctgggaaatattttcc
ttaggtgcttctccataccctggagtaaagattgatgaggaattttgtaggcgattgaaa
gaaggcactagaatgagggcccctgattataccacaccagaaatgtaccagaccatgctt
gactgctggcatggggagcccagtcagagacccacgttttcagagttggtggaacatttg
ggaaatctgttacaagctaatgctcagcaggatggcaaagactatattgttctcccgata
tcagagactttgagcatggaagaggattctggactctctctgcctacctcacctgtttcc
tgtatggaggaagaggaagtgtgtgaccccaaattccattatgacaacacagcaggaatc
agtcagtatctgcagaccagtaagcgaaagagccggcccgtgagtgtaaaaacatttgaa
gatatcccgttggaagaaccagaagtaaaagtaatcccagatgacaaccagacggacagt
ggtatggttcttgcatcagaagagctgaaaaccttggaagacagaaccaaattagctcca
tcttttagtggactgatgcccagcaaaagcaaggagtccgtggcatccgaaggctcaaac
cacacgagtggctaccagtccgggtatcactcggacgacacagacaccactgtgtactcc
agcgaggaggcagaacttttaaagctggtggagattggaccacaagctggcagtgcagcc
cagattctccagcctgactctggacccgcgttgggctctcctcctgtttaa
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